Basic Information

Gene Symbol
RREB1
Assembly
GCA_005876895.1
Location
VCKU01000095.1:10394756-10400838[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.025 2 8.9 0.8 1 21 181 201 181 203 0.93
2 11 0.00017 0.014 15.7 0.2 1 23 213 235 213 235 0.98
3 11 0.44 36 5.0 3.8 2 19 408 425 408 427 0.97
4 11 0.028 2.3 8.7 0.0 1 23 572 594 572 594 0.97
5 11 8.6e-06 0.0007 19.8 0.7 1 23 604 626 604 626 0.99
6 11 0.00058 0.047 14.1 2.0 1 23 632 655 632 655 0.97
7 11 0.0021 0.17 12.3 2.0 1 23 889 912 889 912 0.95
8 11 6e-05 0.0049 17.1 0.3 2 23 1314 1335 1313 1335 0.97
9 11 0.1 8.3 7.0 6.3 1 23 1341 1364 1341 1364 0.97
10 11 0.0084 0.68 10.4 0.6 3 23 1565 1585 1563 1585 0.95
11 11 0.00093 0.076 13.4 4.8 1 23 1591 1613 1591 1613 0.99

Sequence Information

Coding Sequence
ATGCTGGcaacacagcaacagcagcagcagcagccaccccAGCCACACAGCAGTGCCACCGCCGCCTCCGTCACACAGGCTGCGATGGAGCGCCAGCGACGCGAGTCCACCACATCGGAGTCCTCGCTGGAGCATCTCGACCTCGGCCGCACACCAAAGAAgctgagcagcagcagcggcccACAGCCCACATCGACGCCGCACGACACGGCCACAGCGTCGGCGGTGGTGTCAGCGTCGCGCAAGCGGAAGCTGCGccagcaccaacagcagcagcagcaggatctGCTCAGcgacgacgaggaggaggaggaggagctgcgTCCGCTGGAGGAGACGATGGCAGTGCAACGGCCGCGCCACAAGCAGCGACGGAACGGTCCCGCCTCCGCGGCGGCGGCCAGCGCCAGCATCGTGATGGACTACAGTGCCGGCGATGCCAGTTCGCTGCGCAAGAAGTTCCGGCTGAACCGCAGCGGCGCCAATGGAGATCTCTCAGACGGCGAGTCCGGCATCGGGGCTGGCGACGAGCACATGAAGTACCTCTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACCAACCACATCAGGTGCCACAACTACGCCAACGGCGACACCGAGAATTACACCTGCCGCATCTGCTCCAAGGTGCTCTCCTCGGCCTCATCGCTAGACAGACACGTGCTGGTGCACACGGGCGAGCGTCCTGCCCACAGCCACACCCATAGCCATGGGAGTAGTCACgcccgctcccgctcccgcgCCCACGCTCACACccacatcaacaacaacaacaatcccCATAAGGCGAACAACAACCACAAggagatgcagcagcagcagcagcagatccaGGAGCGGATCAAGCAGCGTCGCCCCAAGACCAccatcaacaacaacatcatcgACGATGGCTCCCACGCGGAGGAGGACGAAGAGGAGCGTGACGATcgggagggggagggggaggaggagcaCCACGATCCGGACACCGAAGATGATGTGGCCATGCCCCTCTCCATTACGAGCACCCCGGATGTGGCCACCCTGCTGGCCGGAGTCAATGCATCCTCGCGGGCTGCCTCGCGCTCCCGCTCACCCTCGCCGGCCATGCCCCTGCTGAGCTGCCCCGCCTGTGGGGCCTCCGACTTTGATTCGCTGCCAGGGCTGTGCGCCCACCTGGACGCCCGACACTCGGACATACCCGCCAAGTGCCGCGACTGCGACGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCGCACTGCTGCCGCGGCCTGGTGGGGGTGGATCTGCCGCCGCTCCTGGGGGCCAGCAGCTCACCGCTGCACCAGGGCGAGGATGAGGACGACGAGGATGCCGAGGACGAGGCCAGGACCGAGCGGGAGGCCGAACAGCACGGGGACTTCTTCCAGCAGCTGTACCTCAAGAGCAAGgcagccgctgccgctgtcgcCGGGGCATCCAGCTCCTCGCCCCCGTCCCCCATCAAGCACGAGCCGGCGGACAGCAAGGACCTGGCTGACATCCAGAGCATCCTCAACATGACCAGCTCCAGCTGCACCTCCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAGTACAGCCTCGACGGCCGCGaccaggaggaggaggcccAAGATGTCTTCACCTCGGAGTTCCGCCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGTGCGGCCGTGTTCCCCAATCTGCGCGCCCTCAAGGGCCACAACCGGGTGCATCTCGGCTCCGTTGGCCCCTCCGGCCCGTTCCGTTGCAACATGTGTCCGTATGCCGTCTGCGACAAGGCCGCCCTCGTCCGCCACATGCGCACCCACAACGGGGACCGACCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGGCATCTGCGCAATCGTCACGGCAAGACCAGTCGCGAGGACGTGAAGCGGGCCATCGTCTACCATCCGGCGGAGGACGCCAGCTGCGAGGACAGCAAGTCGCGCCTGGGGCTCGGCGATGATCTGGCCGATCTGAGCTTCCGCTCGGTGTCGCCGCccccaccgccgccgccggcCCCCACCAGTGCTCCGATTGCCGAGGGCTCACAGCTGAAGCACATGCTCCTGGGAGAGCCGTCGCCGCCATTGCATACCCCCCCAGtggccgctgctgcttctgtggCCGGACCACCATCCAAGATCCAGGTGAAGAGCCTCGACCAGCTGGTGGACAAGAAACAGCCTGCCGCTGGCCCTGCCCTCGACTTTAGCATGGATGTGCTGGATCTCAGCAAGAAGCCCAACACTGGAGGATCAGCCTCGgcctctgcctccgcctccgcctctgcctcGTCGGCCCCCTCAACGCAGCTGTTCCGCAACCTGATGTTCCAGACACAGACGCCGGGCTTTCCCTTCTTCGGATTCATGGCCCCGCCTCCACCACAGGGCAGTGCCGAGAAGCCGCCGCAGCTGAGTCCGCCCACGCGGATGGGGGCCCTGCCCCTGCCGATGCCAGTGGGCGTGCCTGTTCCGTCTGGCGGCCCCGTCAAGATGGTCATCAAGAACGGAGTGCTGATGCCCAAACAGAAGCAGCGCCGCTACCGCACCGAACGGCCCTTCGCCTGTGAGCACTGCTCGGCCCGCTTCACCCTGCGCTCCAACATGGAGCGCCACgtgaagcagcagcatcccCAGTTCTATGCCCAGCGCCAGCGGAGCGGACACCACGTGATGCGCGGACGCGGTGCCTCCAACGCCGCAGCGGCCGTGgccgcagccgccgccgcagcgGCAGCCATGAGCCAGGGCGGATCCGGAGCGGGCCATGTGCACGCCCATGCCCCCATCTCGGAGCAGGTGAAGTACGCCATCCTGGCGCAACAGCTGAAGTCGCACAAGAACACGGATCTGCTGCAGCAGGCTCTGGCACACGGATCCAGCAGCGTGGCCGGTGGCAATCAACTCCTGCACTTTGGCTATGGCCCGCCCCAGGCGCAGTCGCACTCCCAGTCACAGTCCCACAACCACACCCaatcccactcccactccctctccctctcccagTCGCAGTCGAGTAGCCATGGCCATGCTCAGTCCAGTTCTGGCTCCCATCTGCCGCATCTGGTGAATGGGATCCACAATGGGAGCAATGGGAACAACGGCCAGGCGAGTGCCATCGATGACGACGAGCCCAAGCTGATCATTGACGAGGATGAGGATGGCGAGGGCGACGTGGAGGAGTTCGACGAGgacgatgaggaggaggaggatgagcCCGAGGACGAGGAcccggagccagagccaatGGAGGAGCCGGAACAGGTGCACGACGAGGAGCCAGAGGACGAGGATCTGGAGCTGCCCAAGCCCCTGGAGCACATCTCACAGCCCAGTGCTGCAGCGGCCAATGAGGCGGCCAAGAAGATGGCCGAGACAATTCTCGAGCAGGCCATCAAGGCGGGCAAGGCCAcacccactgccactggcacgCCCATGAGCACGCGCACGCCGTCACCCAGTCCGGAGCCCACGAACAACGCCATGGCAGAGCCGAGTCCCCCGAATCCCACCATGAAGTCGATGATCGCCCAGGCCGAGTCGGTGGCCAAGTCTCTGAAGGAGGTCGCCAGCTCTCCGTTCAAGGACGAGTCGCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCAGCCAGATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGATGAGGAGGGTCTCGTGGCCTCCGGCAGCGCCAGCGAGAGCAACAATTCTGGAACGGAGGACgtcaccagcagcagctccggCAGCGAGCCGAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAATCGCGTCTCGTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGACGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCACTGCTCTTCACCACCAAGAGCAACTGTGACCGCCATCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTGGAGGAGATCGAGCTCGAGGAGCAGCGTCGTCGCCAGGAGGCGGAGAGGGAGCGCGAACGTGAGCGGGAGCtggaactggagctggagcgGGAGCGCGAGAAGGAGCGGGAGCGCGAACGAGAACTGGAGCGGGAGCGCGAGCGCGAGAAGGAACGTCTGGTGCTCATCCAGAAGCTGGCGGCTCAGATGAATGCCGCCGCAgcggccgctgctgctgcctcggCTACCGATGCCGGCGCTGGCGGAGATCTGCCGTACAAGTGCCACCTGTGCGAGGGCTCCTTTGCCGAGCGTCTGCACTGCCTCGAGCACATCAAGCAGACGCATGCCCACGAGTTTGCCCTGCTGCTGGCCAAGGGAGCCATCGAGCCGGAGTCCCGAGCCGGGGAGTCCAACCACCAGCAGCTgctccaacagcagcagagcacCCCGGGCGCCGGTTCCGACGATGAGGCgagtggcggtggcggtgcaCGCGGTGCCTCTGGCAAATATCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGTCTGCGCCGCTTCTGGTCCACTGAGGACCTGCGCCGGCACATGCGCACCCATTCCGGGGAGCGGCCGTTCCAGTGCGAGATCTGCCTCCGCAAGTTCACCCTCAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGCGGACGCGCCCACAACGGCGACAATGCCGGCTCCGACTGCTCCGACGACGAGCAGGTCGCCACTCCGCCATCCACCCCAGGACCCACTCCGGCCACCCccaccaccaacaacaacaacagttgccagaacaacaacaacaacaacaacaataacagcaGCAATACCAACGCCAATGCAAAGATGGGGCTGCGTCTGCCGAAGCTGCACGAGCTGCTGGACAAGTCGAGCGAGTGGCGGGCCAGCCGGCTGGGCGAGCACAAGGAGAACATCGGCGAGGCGGCAACACCGTCAGCCGCGGCGGTGGCCAGCTCCGATCTGATCGGAAATCTACTGGGCATCAGCGACCAGGGCATACTCAACAAGCTGCTCTCATCCGCCGACGAGGCGGCCAAGTTCCTGGGCGTGGACAACAAGTAG
Protein Sequence
MLATQQQQQQQPPQPHSSATAASVTQAAMERQRRESTTSESSLEHLDLGRTPKKLSSSSGPQPTSTPHDTATASAVVSASRKRKLRQHQQQQQQDLLSDDEEEEEELRPLEETMAVQRPRHKQRRNGPASAAAASASIVMDYSAGDASSLRKKFRLNRSGANGDLSDGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENYTCRICSKVLSSASSLDRHVLVHTGERPAHSHTHSHGSSHARSRSRAHAHTHINNNNNPHKANNNHKEMQQQQQQIQERIKQRRPKTTINNNIIDDGSHAEEDEEERDDREGEGEEEHHDPDTEDDVAMPLSITSTPDVATLLAGVNASSRAASRSRSPSPAMPLLSCPACGASDFDSLPGLCAHLDARHSDIPAKCRDCDVIFASHRQLQAHCCRGLVGVDLPPLLGASSSPLHQGEDEDDEDAEDEARTEREAEQHGDFFQQLYLKSKAAAAAVAGASSSSPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDQEEEAQDVFTSEFRRMKLRGEFPCKLCAAVFPNLRALKGHNRVHLGSVGPSGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEDSKSRLGLGDDLADLSFRSVSPPPPPPPAPTSAPIAEGSQLKHMLLGEPSPPLHTPPVAAAASVAGPPSKIQVKSLDQLVDKKQPAAGPALDFSMDVLDLSKKPNTGGSASASASASASASSAPSTQLFRNLMFQTQTPGFPFFGFMAPPPPQGSAEKPPQLSPPTRMGALPLPMPVGVPVPSGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAVAAAAAAAAAMSQGGSGAGHVHAHAPISEQVKYAILAQQLKSHKNTDLLQQALAHGSSSVAGGNQLLHFGYGPPQAQSHSQSQSHNHTQSHSHSLSLSQSQSSSHGHAQSSSGSHLPHLVNGIHNGSNGNNGQASAIDDDEPKLIIDEDEDGEGDVEEFDEDDEEEEDEPEDEDPEPEPMEEPEQVHDEEPEDEDLELPKPLEHISQPSAAAANEAAKKMAETILEQAIKAGKATPTATGTPMSTRTPSPSPEPTNNAMAEPSPPNPTMKSMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSSQMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERERELELELEREREKERERERELEREREREKERLVLIQKLAAQMNAAAAAAAAASATDAGAGGDLPYKCHLCEGSFAERLHCLEHIKQTHAHEFALLLAKGAIEPESRAGESNHQQLLQQQQSTPGAGSDDEASGGGGARGASGKYPDYSNRKVICAFCLRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRAHNGDNAGSDCSDDEQVATPPSTPGPTPATPTTNNNNSCQNNNNNNNNNSSNTNANAKMGLRLPKLHELLDKSSEWRASRLGEHKENIGEAATPSAAAVASSDLIGNLLGISDQGILNKLLSSADEAAKFLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00474019;
90% Identity
-
80% Identity
-