Dgua003078.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila guanche
Gene Symbol
RREB1
Assembly
GCA_900245975.1
Location
NW:8353381-8364266[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.031 1.8 8.7 0.8 1 21 251 271 251 273 0.93
2 12 0.00022 0.013 15.5 0.2 1 23 283 305 283 305 0.98
3 12 7e-05 0.0042 17.0 7.3 1 23 311 333 311 333 0.98
4 12 2.5 1.5e+02 2.7 3.6 2 19 580 597 580 599 0.97
5 12 0.035 2.1 8.5 0.0 1 23 751 773 751 773 0.97
6 12 1.1e-05 0.00063 19.6 0.7 1 23 783 805 783 805 0.99
7 12 0.00072 0.043 13.9 2.0 1 23 811 834 811 834 0.97
8 12 0.0026 0.15 12.1 2.0 1 23 1126 1149 1126 1149 0.95
9 12 7.5e-05 0.0044 16.9 0.3 2 23 1557 1578 1556 1578 0.97
10 12 0.13 7.4 6.8 6.3 1 23 1584 1607 1584 1607 0.97
11 12 0.01 0.62 10.2 0.6 3 23 1812 1832 1810 1832 0.95
12 12 0.0012 0.069 13.2 4.8 1 23 1838 1860 1838 1860 0.99

Sequence Information

Coding Sequence
ATGTTGGCAGcagcccagcaacagcaaccgcagcagccaacccagcagccacacagcacGGCCACGgtcagcgccagcgccagcgccagtgccACTCAGTCAGCAATGGAGCGTCAGCGCCGCGAGTCCACCACATCGGAGTCCTCGCTGGAGCATCTCGACCTCGGTCGCACACCAAAgaagctgagcagcagcagcggcccaCAGCCCACATCGACGCCACACGACACGGCCCCGGCATCGTCGCGCAAGCGCAAGCTGcgacagcaccaacaacagcatcagcagcagcagcagcaggatctgCTTAgtgacgacgaggaggaggaggaggggccACGCGCACTGGAGGAGACGGTGGCTGTGCAGCGGCCGCGCCACAAGCAGCGACGCAATGCTGCCTCCAGCGCGGCGGCCAGCGCCAGCATCGTGATGGACTACAGTGCCGGCGACGCCAGTTCGCTGCGCAAGAAGTTCCGACTGAACCGCAGCGCCGCTGCCGCTAACGGCGACCTCTCGGAGTCCGGATTCGTGGACgccagcagctacagcagcagtcaTGCAGCCGCGGCCGCCGTCTCTGCTGCAGCGCAGCAGGCGTCGAatgcctccagcagcagcagcagcaatagcagcggtagtggcagcggcagcggtagcggcagcggcagctcggGCGCCTCTTCGCCGGagggcctgtgcctgtccaGCGGCGAGTCCGGCATCGGGGCCGGCGACGAGCACATGAAGTACCTCTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACCAACCACATCAGGTGCCACAACTACGCCAACGGCGACACCGAGAACTACACGTGTCGCATCTGCTCGAAGGTGCTCTCTTCGGCCTCGTCGCTGGACAGACACGTGCTGGTGCACACTGGCGAGCGTCCGTTCAACTGCCGCTACTGCCACCTGACCTTCACCACCAACGGCAACATGCACCGCCACATGCGCACCCACAAGCAGCACCAGTCGACGTCGCAGCAGAGCGCCTCtctgtcgcagtcgcagtcacagtcacagtcgcagcagcagcgacgcctctcccagcagcagcagcaacagcagcagcagcagcagcagcagcagcagctgtcactGGGTGGGCATACGGGACGTGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCCACGGATGTGTCCAGTGCACACAGCCATGCCCACAGCCATGGGAGCAGCaacgcccacacccacgcccacaccaacaacaacaacaccaacagcaacaacaacaacaacaataatccTCACAAGGcgaacaacaaccacaaggagctgcagcagatcaAGCAGCGTCGCCCCAAGACcaccatcaacaacaacaacatcatcgACGATGGCTGCCAGGCAGGagcggagcaggaggagcaggtgaaggagctgcaactgcagctggagctggagctggaggagcccAAGATGAAGGAGGAGCATCTAGATCCAGACACCGATGAGGATATGGCCATGCCGCTATCCATTACGAGCACCCCGGATGTGGCCACCCTGCTGGCCGGAGTCAATGCATCCTCGCGGGCTGCCTCGCgctcccgctccagctccagctcccccGCCCCGGCCATGCCCCTGCTGAGCTGCCCCGCGTGCGGCGCCTCCGACTTTGAAACGCTGCCGGGGCTGTGCGCCCACCTGGATGCCCGCCACTCGGACATACCCGCCAAGTGCCGCGAGTGCGAGGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCGCACTGCTGCCGCGGCCTGGCGGGCGTGGATCTGCCGCCCCTGCTGGGCGCCAGCAGCTCCCCGCTGCACCATGGCGAAGGGGAgaatgaggaggaggacgaggacgaggccaGGACCGAGCGCGAGGCGGAGCAGGAGTTTTTCCAGCAGCTGTACCTCAAGGGcaaggcagccgccgccgccgccgctgccgctgccgcagccgcagctgccgccggGGCATCCACCTCAGCGCCGCCGTCGCCCATCAAGCACGAGCCGGCGGACAGCAAGGATCTGGCCGACATCCAGAGCATCCTGAACAtgaccagctccagctgcacctCCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAGTACAGCCTCGACGGGCGCgaccaggaggaggaggcccaGGACGTCTTCACCTCCGAGTTCCGGCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCGCCGCCGTTTTCCCCAACCTGCGCGCCCTCAAGGGCCACAACCGGGTGCATCTCGGCTCCGTCGGCCCCTCCGGCCCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCCGCCCTCGTGCGCCACATGCGCACCCACAACGGGGATCGGCCCTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGGCATCTGCGCAACCGGCACGGCAAGACCAGCCGCGAGGACGTGAAGCGGGCCATCGTCTACCATCCGGCAGAGGACGCCAGCTGCGAGGACGGCAAGTCGCGGCTAGGCCTCGGCGACGATCTGGCCGATCTGAGCTTCCGCTCCGTCTccccaccaccgccgccgccgcccccgCCCACTGTGCCGATCGCCGAGGGCGGCTCCCAGCTGAAGCACATGCTCCTGGGAGAGCCCACAGCTGTCGCCGCAGGGAGCGCTGCTGTCGCCGGGCCACCATCCAAGATCCAGGTGAAGAGCCTCGACCAGCTGGTGGACAAGAAGCAGCCTCCATCcgcaggcggcagcggcacagccCTGGACTTTAGCATGGATGTGCTGGATCTCAGCAAGAAGCCAACAGCGGGCGGAGCCTCCggttccgcttccgcttctggcacagccacagcgacacCCTCAACAGTGCCGGAACTGTCCGCCGtcctggagcagcagcagcagcagcagcagcaacttctgctcgcccagcagcagttcttcggaggagcagcagcagcagcaggaggaggagctgcagctggagcaggtGGAGCAGGCGATGCCGCCTCCCAGTACATGCAGCAGCTGTTCCGCAACCTCATGTTCCAGTCACAGACGCCGGGCTTCCCGTTCTTTGGGTTCATGGCCCCGCCGCCGCCTCAGGGCAATGCCGagaagcagccgccgcagctgaGTCCTCCGTCGCGCATGGGCAgcatgccgctgccgctgccgctgccgatgccgatgccggtGGGCGTGCCCGTGCCGCCCGGCGGCCCCGTCAAGATGGTCATCAAGAACGGAGTGCTGATgcccaagcagaagcagcgccgCTACCGCACCGAGCGGCCCTTCGCCTGCGAGCACTGCTCCGCGCGCTTCACCCTGCGCTCGAACATGGAGCGGCAcgtgaagcagcagcatccccagTTCTATGCCCAGCGACAGCGCAGCGGACACCACGTGATGCGCGGACGCGGTGCGTCCAATGCCGCGGCAGCTGtggccgcagccgctgccgcagcggcagccatgAGCCAGGGCGGCTCGGGGGCGGGCCATGTCCACGGCCATGCCCCCATCTCGGAGCAGGTGAAGTACGCCATCCTGGCGCAGCAGCTGAAGGCGCACAAGAACACggatctgctgcagcaggcgctggCCCATGGCTCCAGCAGCGTGGCCGGTGCCAATCCCCTCCTGCAGCACTTTGGCTACGCCCCACCACCCTCGCACTTGCAcccacactcccactcccactccaactcccactcccactcccactcgcactcCCATTCAcactcgcagtcgcagtcccacgGCCACGCCCAGTCGTCCGGCTCGTCGCATCTGGTGAATGGCATCCACAATGGGATTGGCCCAGCGGCGGCGAGCGccatcgatgatgatgagccgAAGCTGATCAttgacgaggatgaggatgtcGAGGGGGATGTGGAGGAgttcgacgacgacgacgacgaagaggaggaggaggaggaggatgagcacgaggacgaggagccggaggagccagagccaatgGATGAGTCGGAGCAGGCGCAGGACGAGCcgaaagaggaggagcaggagccgccCAAGAAGCCCCTGGAGCagtcggcatcggcatcggcagccCCTGAGGCGGCCAAGAAGATGGCCGACACCATCCTCGAGCAGGCCATCAAGGCGGGCAAGGCGGGCAAGTCGGCGACGCCCACTGCCaggccctcgccctcgcccttgCCCTCACCCTCAGCCTCACCCGCGGCATCGCCGATCGAGATCAATGCAATGCCAGAGCCGAGTCCACCGAATCCCACAATGAAGTCCATGATCGCCCAGGCCGAGGCGGTGGCCAAGTCGCTGAAGGAGGTGGCCAGCTCGCCGTTCAAGGACGAGTCACAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAAcgccaccagcagccagaTGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTCGTGGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACGGAGGAcgtcaccagcagcagctccggcaGCGAGCCGAAGAAGAAGTCCGCCTACAGCCTGGCGCCCAACCGCGTCTCCTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGACGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACCAAGAGCAACTGCGACCGCCACCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATTCCCGTGCCCAAGTCCGTCGAGGAGatcgagctggaggagcagcgtcGCCGCCAGGAGGCAGAGCGCGAACGGGAGCGCGAGCGCGAGCGGGAGCTCGagctggagcgggagcgggagcgcgagaagcagctggagctggagcaggagctggagcgggagcGCGAAAAGGAGCGCCTGCTGCTCATCCAGAAGCTGGCGGCACAAATGaatgccgctgcagctgccgcagctgcagcctcGGCCACTGCCACGGGCGATGCTGGCGCTGGCGGAGATCTGCCGTACAAGTGCCATCTGTGCGAGGGATCGTTCGCCGAGCGGCTGCACTGCCTCGAGCACATCAAGCAGTCGCACGCCCACGACTTTGCCCTGCTCCTGGCCAAGGGAGCCATCGAGCCGGAGGCAGGCACTGCCCGTCCGAGTGAgtccaaccagcagcagcagcagcagcagcagagcactcCGGGTGCCGGCTCCGACGATGAGGCGAGTGGCGGAGGGGCGCGCGGTGGCTCTGGCAAGTATCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCCTGCGCCGCTTCTGGTCCACCGAGGACCTGCGCCGCCACATGCGCACCCACTCCGGCGAGCGGCCGTTCCAGTGCGAGATTTGCCTGCGGAAGTTCACCCTGAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGCGGACGCGCCCACAACGGGGACAATCCGGGGTCCGACTGCTCCGACGATGAGCAGGTCGCCACTCCGCCACCCACCCCGGGACCCGCTCCGGCCTCAGCCacccccaacaacaacaatagctgccagaacaacaacaacaacaacagcaacaacagcaacagcaacagcaacagcacgaACGGCAAGCTGGGTCTGCGCCTGCCGAAGCTGCACGAGCTGCTGGACAAGTCGagcgagtggcgagtggccAGCCGGCTGGGGGAGCACAAGGAGAACATCGGCGAGGCAGCGACGCCGCTGCCGTCAGTGGCCGCCTCGGTGGCCAGCTCCGATCTGATCGGCAACCTGCTGGGCATCAGCGACCAGGGCATCCTGAACAAGCTGCTCTCCTCCGCCGACGAGGCGGCCAAGCTCCTGGGAGTGGAGAACAAGTAG
Protein Sequence
MLAAAQQQQPQQPTQQPHSTATVSASASASATQSAMERQRRESTTSESSLEHLDLGRTPKKLSSSSGPQPTSTPHDTAPASSRKRKLRQHQQQHQQQQQQDLLSDDEEEEEGPRALEETVAVQRPRHKQRRNAASSAAASASIVMDYSAGDASSLRKKFRLNRSAAAANGDLSESGFVDASSYSSSHAAAAAVSAAAQQASNASSSSSSNSSGSGSGSGSGSGSSGASSPEGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENYTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQSTSQQSASLSQSQSQSQSQQQRRLSQQQQQQQQQQQQQQQLSLGGHTGRAESYESDASCSTDVSSAHSHAHSHGSSNAHTHAHTNNNNTNSNNNNNNNPHKANNNHKELQQIKQRRPKTTINNNNIIDDGCQAGAEQEEQVKELQLQLELELEEPKMKEEHLDPDTDEDMAMPLSITSTPDVATLLAGVNASSRAASRSRSSSSSPAPAMPLLSCPACGASDFETLPGLCAHLDARHSDIPAKCRECEVIFASHRQLQAHCCRGLAGVDLPPLLGASSSPLHHGEGENEEEDEDEARTEREAEQEFFQQLYLKGKAAAAAAAAAAAAAAAAGASTSAPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDQEEEAQDVFTSEFRRMKLRGEFPCKLCAAVFPNLRALKGHNRVHLGSVGPSGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEDGKSRLGLGDDLADLSFRSVSPPPPPPPPPTVPIAEGGSQLKHMLLGEPTAVAAGSAAVAGPPSKIQVKSLDQLVDKKQPPSAGGSGTALDFSMDVLDLSKKPTAGGASGSASASGTATATPSTVPELSAVLEQQQQQQQQLLLAQQQFFGGAAAAAGGGAAAGAGGAGDAASQYMQQLFRNLMFQSQTPGFPFFGFMAPPPPQGNAEKQPPQLSPPSRMGSMPLPLPLPMPMPVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAVAAAAAAAAAMSQGGSGAGHVHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGANPLLQHFGYAPPPSHLHPHSHSHSNSHSHSHSHSHSHSQSQSHGHAQSSGSSHLVNGIHNGIGPAAASAIDDDEPKLIIDEDEDVEGDVEEFDDDDDEEEEEEEDEHEDEEPEEPEPMDESEQAQDEPKEEEQEPPKKPLEQSASASAAPEAAKKMADTILEQAIKAGKAGKSATPTARPSPSPLPSPSASPAASPIEINAMPEPSPPNPTMKSMIAQAEAVAKSLKEVASSPFKDESQDLVPVAKLVDNATSSQMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERERERELELEREREREKQLELEQELEREREKERLLLIQKLAAQMNAAAAAAAAASATATGDAGAGGDLPYKCHLCEGSFAERLHCLEHIKQSHAHDFALLLAKGAIEPEAGTARPSESNQQQQQQQQSTPGAGSDDEASGGGARGGSGKYPDYSNRKVICAFCLRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRAHNGDNPGSDCSDDEQVATPPPTPGPAPASATPNNNNSCQNNNNNNSNNSNSNSNSTNGKLGLRLPKLHELLDKSSEWRVASRLGEHKENIGEAATPLPSVAASVASSDLIGNLLGISDQGILNKLLSSADEAAKLLGVENK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00474019;
90% Identity
-
80% Identity
-