Dmen021166.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Diarsia mendica
Gene Symbol
-
Assembly
GCA_949316265.1
Location
OX438897.1:7974037-7982703[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 0.013 1.8 10.8 1.6 3 23 743 764 742 764 0.96
2 23 0.036 5 9.4 0.6 1 22 1158 1179 1158 1179 0.95
3 23 9.9 1.4e+03 1.7 0.4 1 22 1221 1242 1221 1244 0.82
4 23 0.0046 0.65 12.2 4.0 2 22 1254 1274 1253 1274 0.93
5 23 0.52 73 5.7 0.1 3 23 1283 1304 1281 1304 0.90
6 23 0.023 3.3 10.0 0.2 3 23 1325 1346 1323 1346 0.96
7 23 0.0044 0.61 12.2 2.5 1 23 1352 1375 1352 1375 0.95
8 23 0.17 23 7.3 0.0 1 23 1401 1424 1401 1424 0.90
9 23 0.055 7.7 8.8 3.3 1 23 1429 1451 1429 1451 0.97
10 23 0.011 1.5 11.0 0.1 1 23 1457 1480 1457 1480 0.95
11 23 0.012 1.7 10.9 1.1 1 23 1493 1515 1493 1515 0.97
12 23 0.00024 0.033 16.2 1.8 1 23 1567 1590 1567 1590 0.97
13 23 0.00017 0.023 16.7 0.9 1 23 1650 1673 1650 1673 0.96
14 23 0.0027 0.37 12.9 2.0 2 23 1700 1722 1699 1722 0.95
15 23 0.052 7.3 8.9 0.1 2 23 1728 1750 1727 1750 0.94
16 23 0.013 1.8 10.7 0.2 1 21 1794 1814 1794 1815 0.95
17 23 0.00056 0.078 15.1 1.0 1 23 1825 1847 1825 1847 0.93
18 23 0.00015 0.021 16.9 0.3 2 23 1940 1962 1940 1962 0.93
19 23 5.2e-07 7.3e-05 24.6 1.4 3 23 1969 1989 1968 1989 0.98
20 23 0.029 4.1 9.7 0.3 1 23 2007 2029 2007 2030 0.95
21 23 0.25 34 6.8 0.0 1 23 2053 2075 2053 2075 0.97
22 23 0.037 5.1 9.4 0.6 1 23 2081 2104 2081 2104 0.95
23 23 0.00034 0.047 15.7 0.4 1 23 2112 2135 2112 2135 0.96

Sequence Information

Coding Sequence
ATGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGACTCGGAACCTCCCGTCCTCGCTTTGAAAATCAAGGACTGTGTGTCTGTACAGATAAACGAAAATGACGACCTGCCCACCAATGTCTGCAGGAAATGCATGGACAATGTCAATAACTGGCATGTTTTTAAAAATGTATGTGAAAGGACACAAAACAAACTACTGTCTCTAAAAGATGGCAACCAACTAGAAGAGGTGAAAATAAAAAGTGAACCACTGTCTGATGAGGCTTATGATGATGGAGTGGCCATTGATGGCTCATATCCTGTCATTGAGAATGCGGGCTATTCAAACAAAGTGCAACCTGAAGGTCCCCCAATCTTGGCTTCACTGGGGCTCACACCAAGAAGTGATAAGAAATGTGTGGACCCACGAATGGATTGGCACCGGGTCCATGCAATTTTGGACATGGTTCAAGACAATGAGGTGATTGACTCTCTGCAGACAAGGGAAGAGTGTGATGTTTTGCAGCATTCTGACCATGACTCAGATACTGAAGCCGAACTCCAAACAGAAATTGATGACAGTTATGTTAATAGCAAAAGCGGATATATttgcaaaaacaaacaagttatgTCAAAAGTTCCACAACTATCAACTTCTGTAAATAATGCCAGAGTAAAAGAAGCTTTCAAACTCAGGAAACGCAAATCAGAAGTTCGTAAACATTGTTCACGGCCTAAAAATGCGTGGCAGTTGTTATTCACTGATGACCTACTGGAGTTAATTGTTGCTTCTACAAATGACAATATTGTGACAAATGGGAAAAGTTTCACGGAGTCAACGAGCGTCAGCGAAATTAAAACGCTTATTGGTATTCTGTATCTACACGGCATAATGCGGCCGACGCATCAGAATTGTAGCGACCTTTGGAACAGTGAATGTGGTGTTCCTTGCGTCAGAAATATCATGAAATACGAAAGGTTCAAATTCCTGCTTCATAACATGAGCTTCGACAAAGAGGACGACAACAGCATTATACAGTTTGACATAATGAAGCGTATGCGTAAAGTATTCGAAATCTTCGCCATGAATTGCAGAACATCTTACGAGATCGAGAATGTCGCGGTTATTGATGAGATCATCGTGCCAGTTTACGGACCTTGCCCATTTCGATACGACATTGATAAGAAACCGCTGAAGAGAGGCTTAAAGGTGGTATTGCTGGTTGATTCATCCACATTCTATGTGAGCAATTTAGACGTCATCACTGACCTCTACTTCGGTGCCAAGGATATAACGAAAAAAATGGTTCAGCATTTGGCTGGTACTGGCAGAACTATTGTTATGGACAGTTGGTTCACTTCTTCTTCACTGATGGATACCCTTAAAAATGAGTATCAGTTGTATTCTATCGCAGCCTTGAACCCGAACAGTGATATGATTCCGCCACTCTTCCTGTCTCAGTACAGGAAATGTCGAACATTCATGTCTGGATTTATTGATCACGAAGTATCACTGACATCGTATGTCAATACTGAGGGGAAATCCGTAAATGTATTAACCAATGAGCCTAGATATTACAGGAAAGGTCATATAAATCATACTACAGTTGTTTCTGTGTATAAGAAGAATCAGTCTGCGGTAGAAGTTGTGGATGTTCTGATGAATTACTACACTACAATGCAACACACAAATGATTGgacattgtccttattttttaCTTTGCTAAACATTGCATCTGTTAACGCTCAAGTACTGTGGTGTTCTCAAAACTCGAATGTTACGCAGCGTCGCTTATTTATCAAAGATTTGGCTCTAAGCTTACTGGAACAGGATGAAGAAAGAATCTTAATTTCTCCAATACACGATTTAGAAGAAAGACAAAAGAAATTTTCTATTGTGCGCAGTAATGCCCAACCATATTACAAGAATAGGAGAAGGTGCAAGATATGTGTGAAAACAACGAAACGAGACAGAAGAACCAGACAGTACTGTGTAAAGTGCGGAACATTTATTTGTAAAGAGCATGCTGGTGCGGAGAGTGAGAACAATGAAGAAGACGAGGAAGAAAGTAGCGAACCTGCACAAAATTGTCAGAAAATGCCCCACATGCCCGAGGTGTCTATCACGGTCATGAGGCCTACTGGTGAGACCCTGCACGCTCGCCAAGGTATTCACCAACTCGCTTCGAAACTGTGCCTCGTCTGCGGCCGCTCCTACAGGTACTCTCACAACGCACGCAGACATGAACTTACCTCTCACAGCTTCGACAGATATACAAACAAAATTACTCCTAAAAAAACCCTCAGTCATCTACAACCCAAACTGAGACCGAACCCATTCAACCCCAAAGCACGGATGATGCCGAATCCTATTAGTCATAAGATGCAGTTCATGAACAAGAACATGTCAACAAAAATAATGCCCATAAACAAAGTTATAACGCCACAGAAACCCATTCCAATAAAGACGTCGTCAAAGACACAACATAATTTGCCTTATCCTCTACGCATTAAAGCactcaaagatttacaaattaaGAAGAAGGAGCCTCAAATTCTTAAGACTTTATTAACCACTAAACCTGAAGTTCTGGTCTCAGAACCAGAAATTCTAAATTCTGGGCCTGAAAGTCCCGAAACTTTGATATCTGAGCCTGAAATTGCATCTTTTCAAGTTGAAACTATCCTTACGGAACCGGATGCCGATGCATACGATGATCTACAGCAAGGCGACGAAGAAGCCGATGAAGAAATGCAgaacaatcaaaatcaaaactatgACACTGTTGATATGGACTCTGAGAACGAAATAGAGATTGCTCGTCAGCAAAGCAGTGAACACGACGGCGACGAAAATGCCGATGGGGACGAGAATATGGACCATGATGACGACAATAACATGGAAGGCGGTCAGAGCGACAAcgagaaagatgccaatgacgATACAGCCGACAGTCACGAGAACTTAGAAGAAGATAGTGTTGATATTAAACCTGAAGACCAAATGAAGGAAGAAGACGGCCAAGAGGAGGGAGAACACGAAGAAGAAGTAGAAATGAATCATAATGATAACGAAGAAGAAGACGATGATGACTTGCCTATATCTATAGCGCCCGTAGTGGAAATAAGTGAGGGATTGCAAGGCGATTCGTTCAACAGTGAAGTCATGGAGGAAGAGGAGGAGCTCGACGAAACTGTAGATCCCAATGATCCCAGTGATCCTAATGATCCCAATGACACCGTTCAAGAGGAAGAGCAGGTTAAAGAACTTGACCCTGACAAAACGTATGTTACGAAAACCCAAAGAGACTTCATCAAAAAATTCCGTGATATCATTCAGCAAATCAACACTAAACGTTGTTTATGTTGTGATCGAGAACATCCGCGCAGAAAAGCTGTTATACAACACTTGCAGAAAAACGGACACAAGGTACCAAAACACACATGCTACAATTGTGTCATCACATTCAGTCATATTGGCGCACTACTCAGCCATATGAGGTCGAACTCTTGCACCAATCTGTGGAAGATTATTTACAATGAAAATGGCATTACGGACGACCAGGTTCTTGAAGATGAGCCGAAAGAAGTCAAGGTTGCTTACAAAGATATTTTCAATGCCAGGTCATATGCTTGCAAACTCTGCCCAGCTAAATTCCAACTGAAACAGTTTATAATGAAGCATGTTTTGGATACCCATGAGGATGGACAGTCAAGGATACCACTCTGTTGTGTCCACTGCCGCGCTAGATTCAAAGATAAGAGTTTACTAAAGAAACATATCCGTAAAGGGGATTGTACAGTTTATATTGCTTGCGATTTGTGCTCAGAAACGTTCGGGAACATGCAGAACTTCAACGACCATGCGCTAGCAATCCACGCCGGCAGTTTCGATCAGTCGGATAATCAAAGCAAATGTGTTGACGGTCGACCTACAGACTGTCCCTTGTGTGGAAAGAAAAACAGCAGCTATCCGAATTTAGTGAAACATTTGAAGATTATACATGCTGAGGAAAAACCTCACTACTGCCAGCATTGCGACGCCAAATACGAACAAGCTACTGATCTGAACAAGCACATTTACATGGAGCATTCTGACAGAACACTAGGCATGCCGCCTGCTGAACCGGATATGTCCATAGTGAAGGAGGAAGCTGAGGAGTACCACTACTCCTGCACGGAATGTAATGCCATATTCGAAACTGTTGATGCGTGGACTGATCACCAAGTCGCTGAACATAACCAAGTTGCCCACCACTGTGATCAGTGTGAGAGAAAATTCCTTCGTCCTTCCGAGCTAGCAGAGCACAAGAACACTCATTTGAGGGTTAAGTTTTATCCTTGTAGTGTATGTCCGAACTCTTACAGCACTCCACAGAAACTGTCTGAGCATGTGCAACAGGCACATCCAGGAGTTGGCGCGGTCGCGGCGGGAGAGTCAGAATTCTTCTGCGACATGTGTATCAGAGCATTCAAGAGCCGCCAAGCTTACTCAAATCATATGCGTATTCACTCGAAAGTACCTACTACTAACAGGAAACCGGCTCCAATCAAGGGGGAGGGGGGATTCGCACCTCAAATTATCGGGAAACCAATCAAGCAGTATCCTATGGTTCAACCAGGTTTTGTATCATTTAAATCTAATTACAACATCCCTAACGCTCCATATTCTTGTGACATTTGTGGTAAAGGATTCATGCATAAGAAAAATATATGGAAACACAAGAAAGTTTTACATGCTGATATTTTAGTCGATAGACATGATAGTGAAGAGAACACTATGCAAGCTTCCACAGAAGAGGATGAATTTAACCCTGATGAGAACGGTGCCACTCTCTCGACGCCACAATTTAATAGTTTTAACTTTATGAACTTACCGAACAATGCTCAACAATCAACACCAGAACCATTGCCATACTCGTGTGAGTTATGTGGCAAACGGTTCCCGCTTAAAAACAGTTTATGGAAACACAAACGCGCAAAACACGGTATTGTAAACCCTAGCACTAGTGGTAACAACGATACGTCCACGCCTTCCGCCAGCGGAGAAAGCAGTAGTCGATCTAGCTGCACTATATGCAGAATATCATTTTCAGATAAGAAATCTTACTATCGCCATCGAAAGAATGTCCACAAATCTACCGTTCAAATGTGCAAAATATGTGGCAAACCGCTAAGTTCAACTTTGGAATTATACGAGCACTTGAAAGCTGCTCATGCAAGGGAGTTACTGGGCTATAACGCTAACCAAGGCTCCAGTAAATCACAAGATATGTCACTAGACATGGAACCAGATTATGAAAATGATCAGGAGTCTATCGACCCCAGCGTTGATTACCAAGCGCGGTATCCGTGTGATACTTGTGGCAAACAGTTTGTTGGTTTGCTAGCTTTGCAAAACCACCAGTGCATCAATCAGATATCATCACAGCCACAGACGTTTGACTGCGAGATTTGTCACAAGAGTTACACTTCAATATCTGCGCTAAAAAGCCATCGTGGGTGGCATTTACGTTCACCCGATGGAAAAGCTGCCGCCAACAATTCTGGCCTGTGGATGCCTCAGCACAAAGTTACTAGCAAGATAAGCAAACATGAGGTTGTGGACGCGTCTCAACTGGCTAAGGTCACACACACCCCCACTCCCCCACCTGTAACTGCTACCGTAGCCAAAAGAAGACTACCGCCAGAGGTCGAAGTGACAGTCGTAAACCCGAACAAGAAACTGCGCTCAGACGACTCGGTGGACTTGGATATGCAAAGTACTGGTGCCATCGAGGATAGGTACTGTACGATTTGCGATAAGGAATTCACAAAACGAGCGGCGTACCAGCGCCACATGGATGAGGTACATCAACCGAACTCAGTGTTTTGCCCGGTCTGCGATAAGAGCTTTACAAGAAAGTCCACATTGCTCATTCACATGAAAAAACATTATGAGAGTGGTGAGGGCAGTTCTTCTGCTACAGGTCAAGGAGACGATGATTACTCCTGTGATCTGTGTGGAGCTCAGTATGACAATGATCAGGCATTGAGGGCGCACCGAGCGCGGCACCACGGAGAAGACGAAGAGTCGGCCGAAGAGAGTGACGACGGAAATGTTCCTATTGCTCCTCCCGGTGAATTCACCTGTGCGCAATGTGGCGATGGCGTCGCCACTCCCAGGGACCTCATCGCCCATCGCACAATGCACGCTACTCCCACCAAATTCTTCTGTAACATATGTAAAGTGTACTTCGCTCGGGCGCTCGATCTCTCGTCGCACACTCGGGCGCGACACGCTGACAACGAAAAGGTATTCTTCCCGTGTGCCATGTGCGACAGGTTTTACATGAACAAGAAGAGCTTACAGCGGCACATTGAGATGGCTCACTGA
Protein Sequence
MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLALKIKDCVSVQINENDDLPTNVCRKCMDNVNNWHVFKNVCERTQNKLLSLKDGNQLEEVKIKSEPLSDEAYDDGVAIDGSYPVIENAGYSNKVQPEGPPILASLGLTPRSDKKCVDPRMDWHRVHAILDMVQDNEVIDSLQTREECDVLQHSDHDSDTEAELQTEIDDSYVNSKSGYICKNKQVMSKVPQLSTSVNNARVKEAFKLRKRKSEVRKHCSRPKNAWQLLFTDDLLELIVASTNDNIVTNGKSFTESTSVSEIKTLIGILYLHGIMRPTHQNCSDLWNSECGVPCVRNIMKYERFKFLLHNMSFDKEDDNSIIQFDIMKRMRKVFEIFAMNCRTSYEIENVAVIDEIIVPVYGPCPFRYDIDKKPLKRGLKVVLLVDSSTFYVSNLDVITDLYFGAKDITKKMVQHLAGTGRTIVMDSWFTSSSLMDTLKNEYQLYSIAALNPNSDMIPPLFLSQYRKCRTFMSGFIDHEVSLTSYVNTEGKSVNVLTNEPRYYRKGHINHTTVVSVYKKNQSAVEVVDVLMNYYTTMQHTNDWTLSLFFTLLNIASVNAQVLWCSQNSNVTQRRLFIKDLALSLLEQDEERILISPIHDLEERQKKFSIVRSNAQPYYKNRRRCKICVKTTKRDRRTRQYCVKCGTFICKEHAGAESENNEEDEEESSEPAQNCQKMPHMPEVSITVMRPTGETLHARQGIHQLASKLCLVCGRSYRYSHNARRHELTSHSFDRYTNKITPKKTLSHLQPKLRPNPFNPKARMMPNPISHKMQFMNKNMSTKIMPINKVITPQKPIPIKTSSKTQHNLPYPLRIKALKDLQIKKKEPQILKTLLTTKPEVLVSEPEILNSGPESPETLISEPEIASFQVETILTEPDADAYDDLQQGDEEADEEMQNNQNQNYDTVDMDSENEIEIARQQSSEHDGDENADGDENMDHDDDNNMEGGQSDNEKDANDDTADSHENLEEDSVDIKPEDQMKEEDGQEEGEHEEEVEMNHNDNEEEDDDDLPISIAPVVEISEGLQGDSFNSEVMEEEEELDETVDPNDPSDPNDPNDTVQEEEQVKELDPDKTYVTKTQRDFIKKFRDIIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFSHIGALLSHMRSNSCTNLWKIIYNENGITDDQVLEDEPKEVKVAYKDIFNARSYACKLCPAKFQLKQFIMKHVLDTHEDGQSRIPLCCVHCRARFKDKSLLKKHIRKGDCTVYIACDLCSETFGNMQNFNDHALAIHAGSFDQSDNQSKCVDGRPTDCPLCGKKNSSYPNLVKHLKIIHAEEKPHYCQHCDAKYEQATDLNKHIYMEHSDRTLGMPPAEPDMSIVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCERKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQAHPGVGAVAAGESEFFCDMCIRAFKSRQAYSNHMRIHSKVPTTNRKPAPIKGEGGFAPQIIGKPIKQYPMVQPGFVSFKSNYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILVDRHDSEENTMQASTEEDEFNPDENGATLSTPQFNSFNFMNLPNNAQQSTPEPLPYSCELCGKRFPLKNSLWKHKRAKHGIVNPSTSGNNDTSTPSASGESSSRSSCTICRISFSDKKSYYRHRKNVHKSTVQMCKICGKPLSSTLELYEHLKAAHARELLGYNANQGSSKSQDMSLDMEPDYENDQESIDPSVDYQARYPCDTCGKQFVGLLALQNHQCINQISSQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKISKHEVVDASQLAKVTHTPTPPPVTATVAKRRLPPEVEVTVVNPNKKLRSDDSVDLDMQSTGAIEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYESGEGSSSATGQGDDDYSCDLCGAQYDNDQALRAHRARHHGEDEESAEESDDGNVPIAPPGEFTCAQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00017541;
90% Identity
iTF_01534161; iTF_00375560; iTF_00449482; iTF_00374457; iTF_00810312; iTF_00809383; iTF_01285754; iTF_01247362; iTF_00302371; iTF_00042854; iTF_00785384; iTF_00726700; iTF_01535148; iTF_00928913; iTF_01533268; iTF_00120758; iTF_00685687; iTF_00043771; iTF_01085628;
80% Identity
-