Basic Information

Insect: Pyrrhia umbra
Gene Symbol: Zfa
Assembly: GCA_963891755.1
Location: OY982923.1:11101740-11110531[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.0059 0.51 11.7 1.0 3 23 743 764 742 764 0.96

2 23 0.25 22 6.6 0.3 1 22 1159 1180 1159 1180 0.95

3 23 9.1 8e+02 1.7 0.4 1 22 1222 1243 1222 1245 0.82

4 23 0.02 1.7 10.1 4.8 2 22 1255 1275 1254 1275 0.93

5 23 2.5 2.2e+02 3.5 0.1 3 23 1284 1305 1282 1305 0.89

6 23 0.021 1.9 10.0 0.2 3 23 1326 1347 1324 1347 0.96

7 23 0.0045 0.4 12.1 3.5 1 23 1353 1376 1353 1376 0.95

8 23 0.15 13 7.3 0.0 1 23 1402 1425 1402 1425 0.90

9 23 0.023 2 9.9 3.4 1 23 1430 1452 1430 1452 0.97

10 23 0.011 0.92 10.9 0.2 1 23 1458 1481 1458 1481 0.95

11 23 0.0028 0.25 12.7 1.3 1 23 1494 1516 1494 1516 0.97

12 23 0.00022 0.019 16.2 1.8 1 23 1566 1589 1566 1589 0.97

13 23 0.0022 0.19 13.1 1.3 1 23 1649 1672 1649 1672 0.96

14 23 0.0029 0.25 12.7 2.1 2 23 1699 1721 1698 1721 0.95

15 23 0.048 4.2 8.9 0.1 2 23 1727 1749 1726 1749 0.94

16 23 0.012 1.1 10.7 0.2 1 21 1793 1813 1793 1814 0.95

17 23 0.00051 0.045 15.1 1.0 1 23 1824 1846 1824 1846 0.93

18 23 0.00014 0.012 16.9 0.3 2 23 1939 1961 1939 1961 0.93

19 23 4.8e-07 4.2e-05 24.6 1.4 3 23 1968 1988 1967 1988 0.98

20 23 0.036 3.2 9.3 0.4 1 23 2006 2028 2006 2029 0.95

21 23 0.23 20 6.8 0.0 1 23 2052 2074 2052 2074 0.97

22 23 0.034 2.9 9.4 0.6 1 23 2080 2103 2080 2103 0.95

23 23 0.00031 0.027 15.8 0.4 1 23 2111 2134 2111 2134 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.0059	0.51	11.7	1.0	3	23	743	764	742	764	0.96
2	23	0.25	22	6.6	0.3	1	22	1159	1180	1159	1180	0.95
3	23	9.1	8e+02	1.7	0.4	1	22	1222	1243	1222	1245	0.82
4	23	0.02	1.7	10.1	4.8	2	22	1255	1275	1254	1275	0.93
5	23	2.5	2.2e+02	3.5	0.1	3	23	1284	1305	1282	1305	0.89
6	23	0.021	1.9	10.0	0.2	3	23	1326	1347	1324	1347	0.96
7	23	0.0045	0.4	12.1	3.5	1	23	1353	1376	1353	1376	0.95
8	23	0.15	13	7.3	0.0	1	23	1402	1425	1402	1425	0.90
9	23	0.023	2	9.9	3.4	1	23	1430	1452	1430	1452	0.97
10	23	0.011	0.92	10.9	0.2	1	23	1458	1481	1458	1481	0.95
11	23	0.0028	0.25	12.7	1.3	1	23	1494	1516	1494	1516	0.97
12	23	0.00022	0.019	16.2	1.8	1	23	1566	1589	1566	1589	0.97
13	23	0.0022	0.19	13.1	1.3	1	23	1649	1672	1649	1672	0.96
14	23	0.0029	0.25	12.7	2.1	2	23	1699	1721	1698	1721	0.95
15	23	0.048	4.2	8.9	0.1	2	23	1727	1749	1726	1749	0.94
16	23	0.012	1.1	10.7	0.2	1	21	1793	1813	1793	1814	0.95
17	23	0.00051	0.045	15.1	1.0	1	23	1824	1846	1824	1846	0.93
18	23	0.00014	0.012	16.9	0.3	2	23	1939	1961	1939	1961	0.93
19	23	4.8e-07	4.2e-05	24.6	1.4	3	23	1968	1988	1967	1988	0.98
20	23	0.036	3.2	9.3	0.4	1	23	2006	2028	2006	2029	0.95
21	23	0.23	20	6.8	0.0	1	23	2052	2074	2052	2074	0.97
22	23	0.034	2.9	9.4	0.6	1	23	2080	2103	2080	2103	0.95
23	23	0.00031	0.027	15.8	0.4	1	23	2111	2134	2111	2134	0.96

Sequence Information

Coding Sequence: ATGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGACTCGGAACCTCCCGTCCTCGCTTCTAAAATCAAGGATTGTGTGTCCGTACAGATAAACGAAAATGACGACCTGCCCACAAATGTCTGCAGGAAATGCATGGACAATGTCAATAACTGgcatgtatttaaaaatgtatgtgaaagGACACAAAACAAACTACAGTCTCTAAAAGATGGCAGCCAACTAGAAGAGGTGAAAATAAAAAGTGAACCACTATCTGATGAGGCTTATGATGATGGAGTGGTCATTGATGGCTCATATCCTGTCATTGAGaaTGCCGGCTTGTCAAACAAAGTACAACCTGAAGGTCCCCCAATCTTGGCTTCATTGGGGCTCACACCAAGAAGTGATAAGAAATGTGTGGATCCTCGAATGGATTGGCATCGGGTCCATGCAATTTTGGACATGGTTCAAGACAATGAGGTGATTGATTCTCTGCAGATGAAGGAAGAGTGTGATGTTTTGCAGCATTCTGACCATGACTCTGACACAGAAGCTGAACTCCAACCAgagattgatgatgattttattgattgcaaaaGCGGTTAcatatgcaaaaataaaaaagtcatatcAAAAGTCCCAAAACTATCACCTTCTGTAAATAATGCCAGAGTGAAAGAAGCTTTCAAACTCAGAAAACGTAAATCAGAAGTCCGTAAACATTGTGCACGACCTAAAAATGCGTGGCAGTTGTTATTCACCGATGACCTACTAGAATTGATAGTCGCCTCAACTAATGAAAATATTGTGACTAATGGGAAAAGTTTTACAGAATCAACTAGCGTCAGCGAAATTAAAACGCTTATCGGTATTCTGTATTTGCATGGCATTATGCGGCCGACGCATCAGAAATGTGCTGACCTTTGGAACAGTGAATGTGGTATTCCTTGCGTTAGAAATGTCATGAAATACGAAAGGTTTAAATACTTGCTTCAAAACATCAGCTTCGATAAAGAGGACGACGACAGCATTATACAGTTTGACATAATGAAGCGTATgcgtaaagtatttgaaatctTCGCCATGAATTGCAGAACATCTCACGAGATCGAGAATATCGCGGTTATTGATGAGATCATCGTGCCAGTTTACGGACCTTGCCCATTTCGATACGAAATTGATAAGAAACCATTGAAGCGGGGTATAAAAATGGTACTGCTGGTTGATTCATCTACATTCTATATGAGCAATTTGGACGTCATAACTGATCCTTATTTTGGCGCTGAGGAGATTACGAAAAAGTTAGTTCAACATTTAGCGGGATCTGGCCGATCAATCGTAATGGACAGTTGGTTTACATCTTCCCCATTGATTGATTGCCTTAGAAATGAGTACCAGTTATTCTCTATTGCAGCCTTGAATCCAAACAGTGATATGATACCACCACTATTTCTTTCACAGTATAGGAAATGTCGAACATTCATGTCTGGATTTATTGATCATGAAGTATCAATGACTTCTTATGTCAATACAGAAGGGAAATCAGTGAATGTATTGACTAACGAGCCTAGATATTATAGGAAAGGTCATATAAATCATACTACAGTTGTATCCATCTACAAGAAGAATCAGTCGGCTGTAGAAGTAGTTGATGTGCTCATGAATTATTACACTACGATGCAACACACAAATGATTGGACTTTGTCTTTATTCTTTACACTACTGAACATAGCCTCGGTCAATGCTCAAGTACTGTGGTGCTCTCAAAATTCGAATGTAACGCAGCGACGATTATTTATCAAAGACTTGGCTTTGAGCTTACTTGAGCCAGATGATGAAAGACTTTTAATATCACCAATACAGGATTTGGATGAGAGGAAAAACAAATTCCCTCTTTTGCAGAGTAATGTCCAACCATATTACAAGAATAGGAGGAGATGCAAAATATGTGTGAAAACAACGAAACGCGATAGGAGAACTAAGCAGTTCTGCATAAAGTGTGGTCAATTTATCTGTAAAGAGCATTCTGGTGCGGAGAGTGAAAACAATGAAGAAGACGAGGAAGAAGTCAATGAGCCTGCACAAAAATTCCCGAAAATGCCCCATATGCCGGAGGTTTCCATTACGGTCATGAGGCCTACAGGTGAAACCTTGCACGCTCGACAGGGTATCCACCAGCTCGCCTCTAAGGACTGCCTCGTCTGCGGACGATCGTACAGGTACTCACACAACGCTCGCAGACATGAACTTACCGCTCACAGCTTCGACAgatatacaaacaaaatcacgCCCAAGAAAACTCTCACTCATCTTCAACCAAAACTCAGACCGAACCCATTCAACCCCAAAGCACGGATGATGCCGAATCCTATTAGTCATAAGATGCAATTCTTGAATAAGAACATCCCAGCGAAAATTATGCCcataaacaaagttgtaacgcCACAGAAACCCATTCCAATCAAAACGTCAAAGACATCGCAAAATAACTTACCTTATCCTCTACGCATTAAAGCactcaaagatttacaaataaagaaaaaggaACCTCAGATCCTTAAGACTTTGCTGACCTCTAAACCTGAAGTACTGGTATCGGAACCTGAAATCCTAAATTCTGGTCCTGAAAGTCCTGAAACATTGATATCCGAACCTGAAATTGCGTCTTTTCAAGTCGAAGCCATTCTGACTGAACCCGACGCTGATGCATACGATCCTCAGCAAGGTGACGAAGAAGCTGATGAAGAAATGCAAAACAATCAAAATCAACACTATGACACTGTTGATATGGAGTCAGATAACGAAATCGAGATTGCTCGTCAGCAAGGTATTGAACAAGAAGGTGACGAAAATGCCGATGGCGAAGAAAATGTCGACCAGTGTGATGACGATAATAACATGGAAGGCGTCCAAAGCGATAACGAGAAAGATGGCAACGAGGATACTGCAGAAAGTCAAGAAAATATCGAAGAAGATGATAGTGTTGATATTAAAGCTGAAGGTGAAATGAAGGATGACGAGGCCCTGGAGGAAAGAGAGCCCGAAGAGGGAGAACACGAAGAGGGAGAGCATGAAGAAATCGAAATGAATCATAACGAAGGTGAGGAAGAAGACGACGATGACCTTCCAATGACATTGGCGCCAGTAGTCGAAATAAATGAGGGCTTGCAAACAAATTCGTTTAACAGCGAAGTTAATGAAGAAGAAGAGGAACTTGACGAAACTGCTGATCCTAATGATACCGTCGATGACGAGGAGCAGGTTAAAGAACTTGACCCCGACAAAACTTATGTAACAAAAACCCAAAGAGACTTCATACAAAAGTACCGTGACGTCATTCAACAAATCAACACAAAGCGATGTCTGTGTTGTGACCGGGAACATCCGCGAAGGAAAGCTGTCATACAGCACTTGCAGAAAAACGGGCACAAGGTACCAAAACACACTTGTTATAATTGTGTCATCACATTCGGCCATATTGGTGCACTACTCAGCCATATGAGATCGAATTCTTGCACCAATTTGTGGAAGATTATCTATAATGAAAATGGCATTACTGATGATTTAGTTCTCGAAGATGAGCCAAAGGAGGTTAAAGTTCAatacaaagatatttttaacgCCAGATCTTACGCATGCAAGCTCTGCCCAGCTAAGTTTCAACTAAAACAGTTCATTATGAAACATGTTTTGGATACACATGAAGATGGACAGTCAAGAGTGCCCCTCTGTTGTGTTCACTGCCGTTCTAGGTTCAAAGATAAAAGTTTACTGAAGAAACACATTCGTAAAGGCGAATGTACTGTATATATTGCTTGCGATTTGTGCACAGAAAAGTTCGGGAATATGCAAGACTTCAATGATCACGCTTTAGCTATTCACGCTGGCAGTTTCGATCAGTCGGATAATCAGAGCAAATGTGTTGACGGTCGACCAACTGATTGTCCTTTGTGCGGTAAGAAAAACAGCAGCTATCCGAATTTAGTGAAACATTTGAAGATTATACACAGCGAGGAGAAACCTCATTACTGCCAGCATTGTGATTCTAAATTCGAACAAGCTACTGATCTGAACAAACACATTTACATGGAGCATTCTGACAGAACATTAGGCATGTCAACCACTGAACCAGATATGTCCATTGTGAAGGAAGAAGCTGAGGAGTATCATTATTCGTGTACGGAGTGTAATGCCATATTCGAAACTGTCGACGCGTGGACTGATCATCAAGTCGCCGAACATAACCAAGTAGCTCACCACTGTGACCAGTGTGAGAAGAAATTCCTTCGACCCTCAGAGCTCGCGGAGCACAAGAACACTCATTTGAGGGTTAAATTCTATCCTTGCAGTGTCTGCCCCAACTCTTATAGCACACCACAGAAGCTGTCTGAGCACGTGCAGCAGTCACATCCAGGAATAGGCGCTGTCGCAGCAACTGAATCTGAATTCTTCTGCGATATTTGCATCAGATCATTCAAAAGTCGCCAAGCGTACTCCAACCATATGCGTATTCATGCTAAAATACCAACTACTAATAGGAAACCAGGCGTAATAAAAGGCGGATTTGCACCACAAATTATTGGAAAGCCTATTAAACAGTATCCTGTGGTACAACCTGGTTTTGTGTCATTTAAACCCAATTATAACATCCCCAACGCTCCATACTCGTGTGACATTTGTGGCAAAGGATTCATGCACAAGAAGAATATATGGAAACATAAGAAAGTATTGCATGCAGACATTTTAGTTGACAGACATGATAGTGAAGAGAACACCATGCAGGCTTCGACTGAAGAGGAAGAATTCAACCCTGACGAGAACGGTGCCGTTCTCTCGACGCCgcaatttaatagttttaactTTTCAAACTTCCCAAACAATGTACAACAAACGACACCAGAAACAATGCCTTACTCGTGTGAATTGTGTTCCAAACGGTTCCCGCTTAGGACTAGCTTGTGGAAACACAAGCGCGCTAAACATGGAATTGTAAACCCCAGCACAAGTGGTAACAATGATACATCGACGCCGTCGGCTAGCGGCGAAGGAAGTAGTAGGTCTAGTTGCACTATATGTAGGATCACATTTTCTGACAAGAAATCTTACTACCGCCACCGAAAGAATGTCCACAAATCCACCGTTCAAATGTGCAAAATATGTGGCAAACCTCTAAGTTCAACCTTGGAATTGTACGAGCATCTGAAGGCTGCTCACGCAAGGGAATTGCTGGGTTATAACGCTAACCAAGGTTCAAGTAAATCTCAAGATATGACACAAGAGATGGAACCCGACTACGAAAATGATCTGGAGTCTGTTGATCCCAGCGTGGATTATCAAGCGAGGTACCCATGCGATACATGTGGCAAACAATTTGTTGGTTTGCTTGCTTTGCAGAACCACCAGTGTATCAATCAGATACAATCACAACCACAAACATTCGACTGCGAGATTTGCCACAAGAGTTACACTTCAATATCTGCACTTAAAAGCCATCGTGGTTGGCATTTGCGTTCTCCCGATGGAAAAGCAGCCGCTAATAATTCTGGGCTTTGGATGCCTCAGCACAAAGTTACTAGCAAGATAAGCAAACATGAAGTCGTGGACGCGTCGCAACTCGCTAAGGTCACACATACTCCTGCTCCCCCACCTGTCACCGCTACCGTAGCGAAAAGAAGACTACCGCCAGAGGTCGAAGTAACAGTTGTAAATCCAAACAAGAAATTACGCTCTGACGATTCCGTCGACATGGATCTGCAAAATTCTGGTGCGATCGAGGATAGGTACTGTACGATTTGCGATAAAGAATTTACAAAACGAGCGGCGTATCAACGCCACATGGACGAGGTGCACCAACCGAACTCTGTGTTTTGCCCGGTCTGTGATAAGAGTTTTACGAGGAAGTCCACATTGCTCATACACATGAAGAAACACTACGAGAGCGGTGAGGGCAGTTCCTCTGCTACTGGTCAAGGGGACGATGATTTCTCATGTGATTTGTGCGGCGCTCAGTATGACAATGATCAAGCGTTGAGGGCGCACCGAGCGAGGCACCACGGGGAAGACGAAGAGTCAGCAGAAGAGAGTGACGATGGAAACGTTCCTATAGCTCCTCCTGGTGAGTTCACGTGTGCGCAGTGCGGCGACGGCGTCGCTACTCCCAGAGACCTCATCGCCCACCGCACAATGCATGCTACCCCCACCAAATTCTTCTGTAACATATGCAAAGTGTACTTCGCTCGGGCGCTCGACCTCTCCTCGCACACTCGGGCGCGACACGCCGACAACGAAAAGGTATTCTTCCCGTGTGCCATGTGCGACAGGTTCTACATGAACAAGAAGAGTTTACAGCGGCACATCGAAATGGCTCACTGA
Protein Sequence: MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLASKIKDCVSVQINENDDLPTNVCRKCMDNVNNWHVFKNVCERTQNKLQSLKDGSQLEEVKIKSEPLSDEAYDDGVVIDGSYPVIENAGLSNKVQPEGPPILASLGLTPRSDKKCVDPRMDWHRVHAILDMVQDNEVIDSLQMKEECDVLQHSDHDSDTEAELQPEIDDDFIDCKSGYICKNKKVISKVPKLSPSVNNARVKEAFKLRKRKSEVRKHCARPKNAWQLLFTDDLLELIVASTNENIVTNGKSFTESTSVSEIKTLIGILYLHGIMRPTHQKCADLWNSECGIPCVRNVMKYERFKYLLQNISFDKEDDDSIIQFDIMKRMRKVFEIFAMNCRTSHEIENIAVIDEIIVPVYGPCPFRYEIDKKPLKRGIKMVLLVDSSTFYMSNLDVITDPYFGAEEITKKLVQHLAGSGRSIVMDSWFTSSPLIDCLRNEYQLFSIAALNPNSDMIPPLFLSQYRKCRTFMSGFIDHEVSMTSYVNTEGKSVNVLTNEPRYYRKGHINHTTVVSIYKKNQSAVEVVDVLMNYYTTMQHTNDWTLSLFFTLLNIASVNAQVLWCSQNSNVTQRRLFIKDLALSLLEPDDERLLISPIQDLDERKNKFPLLQSNVQPYYKNRRRCKICVKTTKRDRRTKQFCIKCGQFICKEHSGAESENNEEDEEEVNEPAQKFPKMPHMPEVSITVMRPTGETLHARQGIHQLASKDCLVCGRSYRYSHNARRHELTAHSFDRYTNKITPKKTLTHLQPKLRPNPFNPKARMMPNPISHKMQFLNKNIPAKIMPINKVVTPQKPIPIKTSKTSQNNLPYPLRIKALKDLQIKKKEPQILKTLLTSKPEVLVSEPEILNSGPESPETLISEPEIASFQVEAILTEPDADAYDPQQGDEEADEEMQNNQNQHYDTVDMESDNEIEIARQQGIEQEGDENADGEENVDQCDDDNNMEGVQSDNEKDGNEDTAESQENIEEDDSVDIKAEGEMKDDEALEEREPEEGEHEEGEHEEIEMNHNEGEEEDDDDLPMTLAPVVEINEGLQTNSFNSEVNEEEEELDETADPNDTVDDEEQVKELDPDKTYVTKTQRDFIQKYRDVIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFGHIGALLSHMRSNSCTNLWKIIYNENGITDDLVLEDEPKEVKVQYKDIFNARSYACKLCPAKFQLKQFIMKHVLDTHEDGQSRVPLCCVHCRSRFKDKSLLKKHIRKGECTVYIACDLCTEKFGNMQDFNDHALAIHAGSFDQSDNQSKCVDGRPTDCPLCGKKNSSYPNLVKHLKIIHSEEKPHYCQHCDSKFEQATDLNKHIYMEHSDRTLGMSTTEPDMSIVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQSHPGIGAVAATESEFFCDICIRSFKSRQAYSNHMRIHAKIPTTNRKPGVIKGGFAPQIIGKPIKQYPVVQPGFVSFKPNYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILVDRHDSEENTMQASTEEEEFNPDENGAVLSTPQFNSFNFSNFPNNVQQTTPETMPYSCELCSKRFPLRTSLWKHKRAKHGIVNPSTSGNNDTSTPSASGEGSSRSSCTICRITFSDKKSYYRHRKNVHKSTVQMCKICGKPLSSTLELYEHLKAAHARELLGYNANQGSSKSQDMTQEMEPDYENDLESVDPSVDYQARYPCDTCGKQFVGLLALQNHQCINQIQSQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKISKHEVVDASQLAKVTHTPAPPPVTATVAKRRLPPEVEVTVVNPNKKLRSDDSVDMDLQNSGAIEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYESGEGSSSATGQGDDDFSCDLCGAQYDNDQALRAHRARHHGEDEESAEESDDGNVPIAPPGEFTCAQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00017541;
90% Identity: iTF_00447463;
80% Identity: -