Basic Information

Insect: Hoplodrina ambigua
Gene Symbol: Zfa
Assembly: GCA_949774945.1
Location: OX458971.1:5143619-5152129[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.0074 0.55 11.4 1.1 3 23 646 667 645 667 0.96

2 23 0.24 18 6.7 0.3 1 22 1055 1076 1055 1076 0.95

3 23 8.5 6.3e+02 1.8 0.4 1 22 1118 1139 1118 1141 0.82

4 23 0.019 1.4 10.1 4.8 2 22 1151 1171 1150 1171 0.93

5 23 0.4 29 6.0 0.1 3 23 1180 1201 1178 1201 0.89

6 23 0.037 2.8 9.2 0.2 3 23 1222 1243 1220 1243 0.95

7 23 0.0042 0.31 12.2 2.4 1 23 1249 1272 1249 1272 0.95

8 23 0.14 11 7.4 0.0 1 23 1298 1321 1298 1321 0.90

9 23 0.021 1.6 9.9 3.4 1 23 1326 1348 1326 1348 0.97

10 23 0.0098 0.73 11.0 0.2 1 23 1354 1377 1354 1377 0.95

11 23 0.0046 0.34 12.1 0.8 1 23 1390 1412 1390 1412 0.97

12 23 0.0002 0.015 16.3 1.8 1 23 1462 1485 1462 1485 0.97

13 23 0.00012 0.009 17.0 0.9 1 23 1545 1568 1545 1568 0.96

14 23 0.0027 0.2 12.8 2.1 2 23 1595 1617 1594 1617 0.95

15 23 0.045 3.3 8.9 0.1 2 23 1623 1645 1622 1645 0.94

16 23 0.011 0.84 10.8 0.2 1 21 1689 1709 1689 1710 0.95

17 23 0.00048 0.035 15.1 1.0 1 23 1720 1742 1720 1742 0.93

18 23 0.00013 0.0094 16.9 0.3 2 23 1834 1856 1834 1856 0.93

19 23 4.5e-07 3.3e-05 24.7 1.4 3 23 1863 1883 1862 1883 0.98

20 23 0.034 2.5 9.3 0.4 1 23 1901 1923 1901 1924 0.95

21 23 0.21 16 6.8 0.0 1 23 1947 1969 1947 1969 0.97

22 23 0.031 2.3 9.4 0.6 1 23 1975 1998 1975 1998 0.95

23 23 0.00029 0.021 15.8 0.4 1 23 2006 2029 2006 2029 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.0074	0.55	11.4	1.1	3	23	646	667	645	667	0.96
2	23	0.24	18	6.7	0.3	1	22	1055	1076	1055	1076	0.95
3	23	8.5	6.3e+02	1.8	0.4	1	22	1118	1139	1118	1141	0.82
4	23	0.019	1.4	10.1	4.8	2	22	1151	1171	1150	1171	0.93
5	23	0.4	29	6.0	0.1	3	23	1180	1201	1178	1201	0.89
6	23	0.037	2.8	9.2	0.2	3	23	1222	1243	1220	1243	0.95
7	23	0.0042	0.31	12.2	2.4	1	23	1249	1272	1249	1272	0.95
8	23	0.14	11	7.4	0.0	1	23	1298	1321	1298	1321	0.90
9	23	0.021	1.6	9.9	3.4	1	23	1326	1348	1326	1348	0.97
10	23	0.0098	0.73	11.0	0.2	1	23	1354	1377	1354	1377	0.95
11	23	0.0046	0.34	12.1	0.8	1	23	1390	1412	1390	1412	0.97
12	23	0.0002	0.015	16.3	1.8	1	23	1462	1485	1462	1485	0.97
13	23	0.00012	0.009	17.0	0.9	1	23	1545	1568	1545	1568	0.96
14	23	0.0027	0.2	12.8	2.1	2	23	1595	1617	1594	1617	0.95
15	23	0.045	3.3	8.9	0.1	2	23	1623	1645	1622	1645	0.94
16	23	0.011	0.84	10.8	0.2	1	21	1689	1709	1689	1710	0.95
17	23	0.00048	0.035	15.1	1.0	1	23	1720	1742	1720	1742	0.93
18	23	0.00013	0.0094	16.9	0.3	2	23	1834	1856	1834	1856	0.93
19	23	4.5e-07	3.3e-05	24.7	1.4	3	23	1863	1883	1862	1883	0.98
20	23	0.034	2.5	9.3	0.4	1	23	1901	1923	1901	1924	0.95
21	23	0.21	16	6.8	0.0	1	23	1947	1969	1947	1969	0.97
22	23	0.031	2.3	9.4	0.6	1	23	1975	1998	1975	1998	0.95
23	23	0.00029	0.021	15.8	0.4	1	23	2006	2029	2006	2029	0.96

Sequence Information

Coding Sequence: atGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCCATTTTTCCTACCACCAGTTCGGATGACTCGGAACCTCCCGTCCTCGCTTTGAAAATCAAGGATTGTGTGTCCGTACAGATAAACGAAAATGATGACCTGCCCACTAATGTCTGCAGGAAATGTATGGACAATGTCAACAACTggcatgtttttaaaaatgtatgtgaaAGGACACAAAACAAACTACTGTCTTTAAAAGATGGCAGCCAACTAGAAGAGgtgaaaataaaaagtgaaCCACTATCTGATGAGGCTTATGATGATGGAGTGGTCATTGATGGCTCATATCCTGTCATTGAGAATGCTGGCTTTTCAAACAAAGTGCAACCTGAAGGTCCCCCAATCTTGGCTTCATTGGGGCTCACACCAAGAAGTGATAAGAAATGTGTGGATCCGCGAATGGATTGGCATCGGGTCCATGCAATTTTGGACATGGTTCAAGACAATGAGGTGATTGACTCCCTACAGACAAAGGAAGAGTGTGACGTATTGCAACATTCGGACCATGATTCAGACACAGAAGCGGAACTCCAACCAGAAATTGATGATTGTTATGTTGATTGCAAAAGTGGTTAcatatgcaaaaataaaaaagtcttttCAAAGGTTCCGAAACAATCTACTTCTGTACAGATTGCCAGACTCAAAGAAGCCTCCAAACTCAGGAAACGTAAATCTGATGTTCGTAAACATTGCTCACGTCCTAAAAACGCGTGGCAGTTGTTATTCACCGATGACCTACTAGAATTGATTGTTGCTTCCACTAATGACAACATTGTGACAAATGGGAAAAGTTTCACGGACTCAACAAGCGTCAGCGAAATTAAAACGCTTATCGGTATTCTGTATCTGCATGGCATAATGCGGCCGACGCATCAGCAATGTAGTGACCTTTGGAACAGTGAATGTGGTGTTCCCTGCGTCAGAAAGGTCATGAAATACGAAAGGTTCAAATTCTTGCTTCAAAACATCAGCTTTGATAAGGAGGACGATGACAGCATAATACAGTTTGACATTATGAAGCGTATGCGTAAAGTATTCGAAATCTTCGCCATGAATTGCAGAACATCTCACGAGATCGAGAATGTCGCAGTTATTGATGAGATCATTGTGCCAGTTTACGGACCTTGCCCATTCCGATACGACATTGATAAGAAACCGCTGAAGCGGGGAATAAAGATGGTACTACTGGTTGATTCATCCACATTCTATATGAGCAATTTAGATGTCATTACTGATCCCTATTTTGGCGCCGAAGAGATTACGAAGAAGTTGGTGCAGCATTTAGCTGGGACTGGCAGATCTATTGTTATGGACAGCTGGTATACATCTTCCACATTGATTGATAGCCTTAAAAATGAGTACCAGTTATTTTCTATTGCAGCTTTGAACCCAAACAGTGATATGATTCCACCTCTATTCCTATCTCAATACCGAAAATGTCGAACATTCATGTCTGCATTTATTGATGATGAAGTATCATTGACATCTTATGTCAATGCTGAGGGGAAATCAGTGAATGTATTGACAAATGAACCTAGATATTACAGAAAAGGTCATATAAACCATACTACAGTTGTGTCGGTGTACAAAAAGAATCAGTCTGCCGTAGAAATTATAGATGTACTCATGAATTATTACACGACAATGCAACACAGTAACGATTGGACACTGTCCCTATTCTTTACGTTGTTGAATATTGCCTCTGGTGCGGAgagtgaaaacaatgaagaagACGAGGAAGAAATGAATGAGCCTGCACAAAATTTCCCAAAAATGCCCCACATGCCTGAAGTGTCCATCACGGTCATGAGGCCTACTGGTGAAACTCTGCATGCACGTCAAGGTATTCACCAACTCGCCTCCAAGCTGTGCCTCGTCTGCGGCCGCTCTTACAGGTACTCTCACAACGCTCGCAGACATGAACTTACCGCTCATAGTTTCGATagatatacaaacaaaattactccTAAAAAAACCCTCAATCATCTACAACCCAAACTCAGACCGAACCCATTCAACCCCAAAGCACGGATGATGCCGAATCCTATTAGTCATAAGATGCAGTTCATGAACAAGAACATCTCAGCAAAAATTATGCCCATGAACAAAATTATAACGCCACAGAAACCCATTCCAATAAAGACGTCAAAGACGACACAAAATAATTTGCCTTATCCTCTACGCATTAAAGCACTCAAAGatttacaaataaagaaaaaggagCCTCAAATTCTAAAGACTTTGTTAACCTCCAAACCTGAAGTTTTGGTGTCGGAACCAGAAATTCTCAATTCCGGGCCTGAAAGTCCAGAAACATTGATTTCTGAGCCTGAAATTGCGTCTTTTCAAGTCGAAGCCATTCTTACGGAACCCGACGCTGACGCATACGATGATCCACAGCAAGGCGATGAAGAAATTGATGAGGATATGCAgaacaatcaaagtcaaaactatGACACGGTCGATATGGATTCTGAGAACGAAATAGAGATTGCTCGTCAGCAAGGCGATGAAAATGAAGGCGAGGAACATGCTGATGGGGATGAGAATATCGatcatgatgatgataataatatggaaGGCGGTCAGAGCGATAACGAGAAAGATGTCAATGACGATACAGCAGAAAGTCAAGAGAACATGGAAGAGGAAGATAGCGTTGACATTAAAGCTGAAAGTGAAATTAAAGATGAAGAGGAGGACCAAGAGGACAGAGATAATGAAGAAATTGAGATGAATCATAACGAAAACGAAGAAGAAGACGATGATGACCTTCCGATATCATTAGCGCCAGTCGTCGAAATAAACGAGGGATTGCAAGCTAACTCGTTTAACAGCGAAGTCAATGAAGACGACGAGGAACTTGACGAAACTAACGATGGTGATACTAACGAAACCCTTGACGAAGAGGAGCAGGTCAAAGAACTTGACCCTGACAAAACATATGTTACAAAAACCCAAAGAGACTTCATCCAAAAATATCGTGACATCATTCAGCAGATCAACACCAAACGTTGTTTATGTTGTGATCGAGAACATCCGCGCAGAAAAGCTGTTATACAACACTTGCAGAAAAACGGACACAAGGTACCAAAACACACGTGTTATAATTGTGTCATCACGTTCGGACATATTGGCGCTCTACTCAGCCACATGAGGTCGAATTCCTGCACTAATTTGTGGAAGATTATTTACAATGAAAATGGCATTACTGATGACTTAGTTCTCGAAGACGAGCCGAAAGAGGTCAAGGTTGCGTACAAAGATATTTTCAATGCCAGGTCATACGCTTGTAAGCTCTGTCCAGCTAAATTCCAACTGAAACAGTTTATAATGAAACATGTTCTAGATACTCATGAGGATGGACAATCAAGGGTACCTCTCTGTTGTGTCCACTGCCGCTCTAGGTTCAAAGATAAGAGCTTACTCAAGAAACACATTCGTAAAGGTGATTGTACAGTTTATATTGCTTGCGATTTGTGTTCAGAAAAGTTCAGAAACGTGCAGGACTTTAATGACCATGCGTTAGCCATCCACGCAGGCAGTTTCGATCAGTCAGATAATCAAAGCAAATGTGTTGACGGTCGTCCCACAGACTGTCCTTTGTGTGGAAAGAAAAACAGTAGCTATCCGAATTTAGTGAAACATTTGAAGTTAATACATGCAGAGGAGAAACCTCATTACTGTCAGCACTGCGACGCTAAATACGAACAAGCTACCGAATTGAACAAACACATTTACATGGAGCATTCTGACAGAACATTAGGCATGCCTCCCACCGAACCTGATATGTCCATTGTGAAGGAAGAAGCGGAGGAGTACCATTACTCCTGTACGGAATGTAATGCCATATTTGAAACTGTCGATGCGTGGACTGATCATCAGGTCGCCGAACACAATCAAGTGGCCCACCACTGTGACCAGTGTGAAAAGAAATTCCTTCGTCCTTCAGAGCTGGCGGAGCATAAGAACACTCACTTAAGGGTTAAGTTTTATCCTTGCAGTGTGTGCCCCAACTCTTACAGCACTCCACAGAAACTGTCTGAGCATGTGCAGCAGTCACATCCAGGGATCGGCGCAGTCGCGGCAACTGAGTCGGAGTTCTTCTGCGACATCTGCATTAGAGCATTCAAAAGTCGCCAAGCTTACTCAAACCATATGCGTATTCACGCTAAAGTTCCTACCACTAACAGGAAACCAGCTGTCGGTAAAGAAGGTTTCGCGCCTCAAGTTATAGGAAAACCCATCAAACAGTATCCTATGGTACAACCTGGTTTTGTATCATTTAAACCTAATTACAACATCCCTAATGCTCCATATTCTTGTGACATTTGTGGAAAAGGATtcatgcacaagaaaaatatatggaaaCATAAGAAAGTGTTGCATGCCGATATTTTAGTCGATAGACATGATAGTGAGGAGAATACTATGCAAGCTTCCACAGAAGAGGAGGAATTCAACCCAGATGAGAACGGAGCAGTTCTGTCAACGCCACAATTTAATAGTTTTAACTTTACCAACTTCCCGAACAATGCTCAACCGACGACACCAGAAACAATGCCTTATTCGTGCGAGTTATGTGGCAAACGGTTCCCGCTTAAGACCAGTTTATGGAAACATAAACGCGCTAAACATGGAATTGTAAACCCTGGCAGCAGTGGTAGTAATGACACATCCACGCCATCCGCTAGCGGGGAAAGCAGTAGTAGATCTAGCTGCACTATATGTAGAATCACATTTTCAGATAAGAAATCTTACTATCGCCATCGAAAGAATGTCCATAAATCTACAGTTCAAATGTGCAAAATCTGTGGAAAACCTCTAAGTTCAACTTTGGAGTTATACGAGCATTTAAAAGCCGCTCATGCAAGGGAATTGCTGGGTTATAACGCTAACCAGGGCTCCAGTAAATCACAAGATATGTCGCAAGAGATGGAACCCGATTATGAAAATGATCAGGAGTCTGTTGACCCCAGCGTCGATTACCAAGCGCGCTACCCATGCGATACATGTGGCAAACAATTTGTCGGTTTGCTAGCATTGCAGAACCACCAATGCATCAACCAGATTCCCGCACAACCACAGACGTTTGACTGCGAAATTTGTCACAAGAGCTACACTTCAATATCTGCGCTAAAGAGCCATCGAGGGTGGCATTTACGTTCGCCAGATGGAAAAGCAGCCGCTAATAATTCAGGTCTTTGGATGCCTCAGCACAAAGTTACTAGCAAGATAAGTAAACATGAAGTTATTGACCCGTCGCAACTAGCTAAGGTCACACATACTCCCACTCCCCCTCCTGTCAGTGCTAGCGCAGCGAAAAGAAGACTGCCGCCGGAGGTCGAAGTAACCGTCGTAAATCCAAACAAGAAATTGCGTTCGGACGACTCTGTGGACTTGGATCAAAGTTCTGGTGCATTAGAGGATAGGTATTGTACGATTTGTGACAAGGAATTTACCAAACGAGCGGCGTATCAGCGCCACATGGACGAAGTGCATCAACCGAACTCTGTGTTTTGCCCAGTTTGTGATAAGAGTTTCACTAGGAAGTCCACATTGCTTATTCACATGAAGAAACACTATGAGAGTGGTGAGGGTAGTTCCTCCGCCACAGGTCAAGGGGATGATGATTTCTCGTGTGATTTGTGTGGCGCTCAGTACGACAACGATCAGGCGTTGAGGGCGCACCGAGCGAGGCATCACGGGGAAGAGGAAGAGTCGGCAGAAGAGAGTGACGACGGTAATGTCCCTGTGGCTCCGCCCGGTGAATTCACATGTGCGCAATGTGGCGATGGTGTCGCTACACCGAGGGACCTCATCGCCCATCGCACAATGCACGCTACTCCCACCAAATTTTTCTGTAACATATGTAAAGTGTACTTCGCTCGGGCGCTCGACCTCTCGTCGCACACCCGGGCGCGACACGCTGACAACGAAAAGGTGTTCTTCCCGTGTGCCATGTGCGACAGATTTTACATGAACAAGAAGAGTTTACAGCGGCACATCGAGATGGCTCACTGA
Protein Sequence: MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLALKIKDCVSVQINENDDLPTNVCRKCMDNVNNWHVFKNVCERTQNKLLSLKDGSQLEEVKIKSEPLSDEAYDDGVVIDGSYPVIENAGFSNKVQPEGPPILASLGLTPRSDKKCVDPRMDWHRVHAILDMVQDNEVIDSLQTKEECDVLQHSDHDSDTEAELQPEIDDCYVDCKSGYICKNKKVFSKVPKQSTSVQIARLKEASKLRKRKSDVRKHCSRPKNAWQLLFTDDLLELIVASTNDNIVTNGKSFTDSTSVSEIKTLIGILYLHGIMRPTHQQCSDLWNSECGVPCVRKVMKYERFKFLLQNISFDKEDDDSIIQFDIMKRMRKVFEIFAMNCRTSHEIENVAVIDEIIVPVYGPCPFRYDIDKKPLKRGIKMVLLVDSSTFYMSNLDVITDPYFGAEEITKKLVQHLAGTGRSIVMDSWYTSSTLIDSLKNEYQLFSIAALNPNSDMIPPLFLSQYRKCRTFMSAFIDDEVSLTSYVNAEGKSVNVLTNEPRYYRKGHINHTTVVSVYKKNQSAVEIIDVLMNYYTTMQHSNDWTLSLFFTLLNIASGAESENNEEDEEEMNEPAQNFPKMPHMPEVSITVMRPTGETLHARQGIHQLASKLCLVCGRSYRYSHNARRHELTAHSFDRYTNKITPKKTLNHLQPKLRPNPFNPKARMMPNPISHKMQFMNKNISAKIMPMNKIITPQKPIPIKTSKTTQNNLPYPLRIKALKDLQIKKKEPQILKTLLTSKPEVLVSEPEILNSGPESPETLISEPEIASFQVEAILTEPDADAYDDPQQGDEEIDEDMQNNQSQNYDTVDMDSENEIEIARQQGDENEGEEHADGDENIDHDDDNNMEGGQSDNEKDVNDDTAESQENMEEEDSVDIKAESEIKDEEEDQEDRDNEEIEMNHNENEEEDDDDLPISLAPVVEINEGLQANSFNSEVNEDDEELDETNDGDTNETLDEEEQVKELDPDKTYVTKTQRDFIQKYRDIIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFGHIGALLSHMRSNSCTNLWKIIYNENGITDDLVLEDEPKEVKVAYKDIFNARSYACKLCPAKFQLKQFIMKHVLDTHEDGQSRVPLCCVHCRSRFKDKSLLKKHIRKGDCTVYIACDLCSEKFRNVQDFNDHALAIHAGSFDQSDNQSKCVDGRPTDCPLCGKKNSSYPNLVKHLKLIHAEEKPHYCQHCDAKYEQATELNKHIYMEHSDRTLGMPPTEPDMSIVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQSHPGIGAVAATESEFFCDICIRAFKSRQAYSNHMRIHAKVPTTNRKPAVGKEGFAPQVIGKPIKQYPMVQPGFVSFKPNYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILVDRHDSEENTMQASTEEEEFNPDENGAVLSTPQFNSFNFTNFPNNAQPTTPETMPYSCELCGKRFPLKTSLWKHKRAKHGIVNPGSSGSNDTSTPSASGESSSRSSCTICRITFSDKKSYYRHRKNVHKSTVQMCKICGKPLSSTLELYEHLKAAHARELLGYNANQGSSKSQDMSQEMEPDYENDQESVDPSVDYQARYPCDTCGKQFVGLLALQNHQCINQIPAQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKISKHEVIDPSQLAKVTHTPTPPPVSASAAKRRLPPEVEVTVVNPNKKLRSDDSVDLDQSSGALEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYESGEGSSSATGQGDDDFSCDLCGAQYDNDQALRAHRARHHGEEEESAEESDDGNVPVAPPGEFTCAQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00017541;
90% Identity: iTF_00447463;
80% Identity: -