Basic Information

Insect: Hoplodrina blanda
Gene Symbol: Zfa
Assembly: GCA_949316365.1
Location: OX438584.1:12009138-12017751[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.008 0.56 11.3 1.1 3 23 745 766 744 766 0.96

2 23 0.26 18 6.6 0.3 1 22 1154 1175 1154 1175 0.95

3 23 9.2 6.4e+02 1.7 0.4 1 22 1217 1238 1217 1240 0.82

4 23 0.02 1.4 10.1 4.8 2 22 1250 1270 1249 1270 0.93

5 23 0.15 10 7.3 0.1 3 23 1279 1300 1277 1300 0.90

6 23 0.02 1.4 10.1 0.2 3 23 1321 1342 1319 1342 0.96

7 23 0.0045 0.31 12.1 2.4 1 23 1348 1371 1348 1371 0.95

8 23 0.15 11 7.3 0.0 1 23 1397 1420 1397 1420 0.90

9 23 0.023 1.6 9.9 3.4 1 23 1425 1447 1425 1447 0.97

10 23 0.011 0.74 10.9 0.2 1 23 1453 1476 1453 1476 0.95

11 23 0.005 0.35 12.0 0.8 1 23 1489 1511 1489 1511 0.97

12 23 0.00022 0.015 16.2 1.8 1 23 1561 1584 1561 1584 0.97

13 23 0.00013 0.0092 16.9 0.9 1 23 1644 1667 1644 1667 0.96

14 23 0.0029 0.2 12.7 2.1 2 23 1694 1716 1693 1716 0.95

15 23 0.049 3.4 8.9 0.1 2 23 1722 1744 1721 1744 0.94

16 23 0.012 0.85 10.8 0.2 1 21 1788 1808 1788 1809 0.95

17 23 0.00052 0.036 15.1 1.0 1 23 1819 1841 1819 1841 0.93

18 23 0.00014 0.0096 16.9 0.3 2 23 1933 1955 1933 1955 0.93

19 23 4.9e-07 3.4e-05 24.6 1.4 3 23 1962 1982 1961 1982 0.98

20 23 0.037 2.6 9.3 0.4 1 23 2000 2022 2000 2023 0.95

21 23 0.23 16 6.8 0.0 1 23 2046 2068 2046 2068 0.97

22 23 0.034 2.4 9.4 0.6 1 23 2074 2097 2074 2097 0.95

23 23 0.00031 0.022 15.8 0.4 1 23 2105 2128 2105 2128 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.008	0.56	11.3	1.1	3	23	745	766	744	766	0.96
2	23	0.26	18	6.6	0.3	1	22	1154	1175	1154	1175	0.95
3	23	9.2	6.4e+02	1.7	0.4	1	22	1217	1238	1217	1240	0.82
4	23	0.02	1.4	10.1	4.8	2	22	1250	1270	1249	1270	0.93
5	23	0.15	10	7.3	0.1	3	23	1279	1300	1277	1300	0.90
6	23	0.02	1.4	10.1	0.2	3	23	1321	1342	1319	1342	0.96
7	23	0.0045	0.31	12.1	2.4	1	23	1348	1371	1348	1371	0.95
8	23	0.15	11	7.3	0.0	1	23	1397	1420	1397	1420	0.90
9	23	0.023	1.6	9.9	3.4	1	23	1425	1447	1425	1447	0.97
10	23	0.011	0.74	10.9	0.2	1	23	1453	1476	1453	1476	0.95
11	23	0.005	0.35	12.0	0.8	1	23	1489	1511	1489	1511	0.97
12	23	0.00022	0.015	16.2	1.8	1	23	1561	1584	1561	1584	0.97
13	23	0.00013	0.0092	16.9	0.9	1	23	1644	1667	1644	1667	0.96
14	23	0.0029	0.2	12.7	2.1	2	23	1694	1716	1693	1716	0.95
15	23	0.049	3.4	8.9	0.1	2	23	1722	1744	1721	1744	0.94
16	23	0.012	0.85	10.8	0.2	1	21	1788	1808	1788	1809	0.95
17	23	0.00052	0.036	15.1	1.0	1	23	1819	1841	1819	1841	0.93
18	23	0.00014	0.0096	16.9	0.3	2	23	1933	1955	1933	1955	0.93
19	23	4.9e-07	3.4e-05	24.6	1.4	3	23	1962	1982	1961	1982	0.98
20	23	0.037	2.6	9.3	0.4	1	23	2000	2022	2000	2023	0.95
21	23	0.23	16	6.8	0.0	1	23	2046	2068	2046	2068	0.97
22	23	0.034	2.4	9.4	0.6	1	23	2074	2097	2074	2097	0.95
23	23	0.00031	0.022	15.8	0.4	1	23	2105	2128	2105	2128	0.96

Sequence Information

Coding Sequence: ATGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGACTCGGAACCTCCCGTCCTCGCTTTGAAAATCAAGGATTGTGTGTCCGTACAGATAAACGAAAATGATGACCTGCCCACTAATGTCTGCAGGAAATGTATGGACAATGTCAATAACTggcatgtttttaaaaatgtatgtgaAAGGACACAAAACAAACTACTGTCTCTAAAAGATGGCAGCCAACTAGAAGAGgtgaaaataaaaagtgaaCCACTATCTGATGAGGCTTATGATGATGGAGTGGTCATTGATGGCTCATATCCTGTCATTGAGAATGCTGGCTTTTCAAACAAAGTGCAACCTGAAGGTCCCCCAATCTTGGCTTCATTGGGGCTCACACCAAGAAGTGATAAGAAATGTGTGGATCCGCGAATGGATTGGCATCGGGTCCATGCAATTTTGGACATGGTTCAAGACAATGAGGTGATTGACTCCCTACAGACAAAGGAAGAGAGTGATGTATTGCAACATTCGGACCATGATTCAGAAACAGAAGCCGAACTCCAACCAGAAATTGATGATTGTTATGTTGATTGCAAAAGCGGTTAcatatgcaaaaataaaaaagtcttttCGAAGATTCCGAAACAATCTACTTCTGTACATATTGCCAGACTCAAAGAAGCCTCCAAACTCAGGAAACGTAAATCTGATGTTCGTAAACATTGTTCACGACCTAAAAACGCGTGGCAGTTGTTATTCACCGATGACCTACTAGAATTGATTGTTGCTTCCACTAATGACAACATTGTGACAAATGGGAAAAGTTTCACGGACTCAACAAGCGTCAGCGAAATTAAAACGCTTATCGGTATTCTGTATCTGCATGGCATAATGCGGCCGACGCATCAGCAGTGTAGTGACCTTTGGAACAGTGAATGTGGTGTTCCTTGCGTCAGAAAGATCATGAAATACGAAAGGTTCAAATTCTTGCTTCAAAACATCAGCTTTGATAAGGAGGACGATGACAGCATAATACAGTTCGACATTATGAAGCGTATGCGTAAAGTATTCGAAATCTTCGCCATGAATTGTAGAACATCTCACGAGATCGAGAATGTCGCAGTTATTGATGAGATCATCGTGCCAGTTTACGGACCTTGCCCATTCCGATACGATATTGATAAGAAACCGCTGAAGCGGGGAATAAAAATGGTACTACTGGTTGATTCATCCACATTCTATATGAGCAATTTAGATGTCATTACTGATCCTTATTTTGGCGCCGAAGAGATAACGAAGAAGTTGGTGCAGCATTTAGCTGGAACTGGCAGATCTATTGTTATGGACAGCTGGTATACATCTTCCACATTGATTGATAGCCTTAAAAATGAGTACCAGTTATTTTCTATTGCAGCTTTGAACCCAAACAGTGATATGATTCCACCTCTGTTCTTATCTCAATACAGAAAATATCGAACATTCATGTCTGCATTTATTGATGATGAAGTATCATTGACATCTTATGTCAATGCTGAGGGGAAATCAGTAAATGTATTGACAAATGAGCCTAGATATTATAGAAAAGGTCATATAAACCATACTACAGTTGTGTCGGTGTACAAGAAGAATCAGTCAGCCGTAGAAATTACAGATGTTCTCATGAATTATTACACGACAATGCAACACACTAACGATTGGACACTGTCCCTATTCTTTACGTTGCTGAATATTGCCTCTGTAAATGCTCAAGTGCTGTGGTGCTCTCAAAACTCGAATGTTACTCAACGTCGCCTATTTATTAAAGATTTAGCGTTAAGCTTACTAGAACCACATGAAGAAAGAATGTTAATATCTCCGATACTTGATTTAGAAGAAAGGAAAAACAAATTTTCTATAGTACGCAGTAATGCACAACCATATTATAAGAATAGGAGAAGGTGTAAAATATGTGTGAAAACAACGAAACGCGATAGGAGAACAAGACAGTTCTGTGTTAAGTGCGGCACATTTATTTGCAAAGAGCATGCAGTCAGTGGTGCGGAGAGTGAAAATAATGAAGAAGACGAGGAAGAAATGAATGAACCTGCACAAAATTTCCCGAAAATGCCCCACATGCCTGAAGTGTCCATCACGGTCATGAGGCCTACTGGTGAAACTCTGCATGCACGTCAAGGTATTCACCAACTCGCCTCCAAGCTGTGCCTCGTCTGCGGCCGCTCTTACAGGTACTCTCACAACGCTCGCAGACATGAACTTACCGCTCATAGTTTCGATagatatacaaacaaaattactcCTAAAAAAACCCTCAATCATCTACAACCCAAACTCAGACCGAATCCATTTAACCCCAAAGCACGGATGATGCCGAATCCTATTAGTCATAAGATGCAGTTCTTGAACAAGAACATCTCAGCAAAAATTATGCCCATGAACAAAATTATAACGCCACAGAAACCCATTCCAATAAAGACGTCAAAGACGACACAAAATAATTTGCCTTATCCCCTACGCATTAAAGCACTCAAAGAtttacaaataaagaaaaaggaGCCTCAAATTCTAAAGACTTTGTTAACCTCCAAACCTGAAGTTTTGGTGTCAGAACCAGAAATTCTTAATTCTGGGCCTGAAAGTCCAGAAACATTGATTTCTGAGCCTGAAATTGCGTCTTTTCAAGTCGAAGCTATTCTTACGGAACCCGACGCTGACGCATACGATGATCCACAGCAAGGCGATGAAGAAGTTGATGAGGATATGCAgaacaatcaaagtcaaaactatGACACGGTCGATATGGATTCTGAGAACGAAATAGAGATTGCTCGTCAGCAAGGGGATGAAAATGAAGGCGAGGAAAATGCTGATGTGGATGAGAATATCGATCACGACgatgataataatatggaaGGCGGTCAGAGCGATAACGAGAAAGATGTCAATGACGATACAGCAGAAAGTCAAGAGAACATGGAAGAGGAAGATAGCGTTGACATTAAAGCTGAAAGTGAAATAAAAGATGAAGAGGAGGACCAAGAGGACAGAGATAATGAAGAAATTGAGATGAATCATAACGAAAACGAAGAAGAAGACGATGATGACCTTCCAATATCATTAGCGCCAGTCGTCGAAATAAACGAGGGATTGCAAGCAAACTCGTTTAACAGCGAAGTCAATGAAGACGATGAGGAACTTGACGAAACTAACGATGGTGATACTAACGAAACCCTCGAAGACGAGGAGCAGGTCAAAGAACTTGACCCTGACAAAACATATGTTACAAAAACCCAAAGAGACTTCATCCAAAAATATCGCGACATCATTCAGCAGATCAACACCAAACGTTGTTTATGTTGTGATCGAGAACATCCGCGCAGAAAAGCTGTTATACAACACTTGCAGAAAAACGGACACAAGGTACCAAAACACACGTGTTATAATTGTGTCATCACGTTCGGACATATTGGCGCTCTACTCAGCCACATGAGGTCGAATTCCTGCACTAATTTGTGGAAGATTATTTACAATGAAAATGGCATTACTGATGATTTAGTTCTCGAAGATGAGCCGAAAGAGGTCAAGGTTGCGTACAAAGATATTTTCAATGCCAGGTCATACGCTTGTAAGCTCTGTCCAGCTAAATTCCAACTGAAACAGTTTATTATGAAACATGTTTTGGATACTCATGAAGATGGACAGTCAAGGGTACCTCTCTGTTGTGTCCACTGCCGCTCTAGGTTCAAAGATAAGAGCTTACTCAAGAAACACATTCGTAAAGGTGATTGTACAGTTTATATTGCTTGCGATTTATGTTCAGAAAAGTTCAGAAACTTGCAGGACTTTAATGACCATGCGTTAGCCATCCACGCTGGCAGTTTCGATCAGTCAGATAATCAAAGCAAATGTGTTGACGGTCGGCCCACTGACTGTCCTTTGTGCGGAAAGAAAAACAGTAGCTATCCGAATTTAGTGAAACATTTGAAGGTAATACATGCAGAGGAGAAACCTCACTACTGTCAGCACTGCGACGCTAAATACGAACAAGCTACTGAATTGAACAAACACATTTACATGGAGCATTCTGACAGAACATTAGGTATGCCGCCCACTGAACCTGATATGTCCATTGTGAAGGAAGAAGCGGAGGAGTACCATTACTCCTGTACGGAATGTAATGCCATATTCGAAACTGTCGATGCGTGGACTGATCATCAAGTCGCCGAACACAACCAAGTGGCCCACCACTGTGATCAGTGTGAGAAGAAATTCCTTCGTCCTTCAGAGCTGGCGGAGCATAAGAACACTCACTTAAGGGTTAAGTTTTATCCTTGCAGTGTGTGCCCCAACTCTTACAGCACTCCACAGAAACTGTCTGAGCATGTGCAGCAGTCACATCCAGGGATCGGCGCAGTCGCGGCAACTGAGTCGGAGTTCTTCTGCGACATCTGCATTAGAGCATTCAAAAGTCGCCAAGCTTACTCAAATCATATGCGTATTCACGCTAAAGTTCCTACCACTAACAGGAAACCAGGTGTCGTTAAAGAAGGTTTCGCGCCTCAAGTTATAGGAAAACCCATCAAACAGTATCCTATGGTACAACCTGGTTTTGTATCATTTAAACCTAATTACAACATCCCTAACGCTCCATATTCTTGTGACATTTGTGGCAAAGGATTCATGCAcaagaaaaatatatggaaaCACAAGAAAGTGTTGCATGCCGATATTTTAGTCGATAGACATGATAGTGAAGAGAATACTATGCAAGCTTCCACAGAAGAGGAGGAATTCAACCCAGATGAGAACGGTGCCGTTCTGACAACGCCACAATTTAAtagttttaactttacgaaCTTCCCGAACAATGCTCAACCAACGACACCAGAAACAATGCCTTATTCGTGTGAGTTATGTGGCAAACGGTTCCCACTTAAGACCAGTTTATGGAAACATAAACGCGCTAAACATGGAATTGTAAACCCTGGCAGCAGTGGTAGCAATGACACATCCACGCCATCTGCTAGCGGGGAAAGCAGTAGTAGATCTAGCTGCACTATATGTAGAATCACATTTTCAGATAAGAAATCTTATTATCGCCATCGAAAGAATGTCCACAAATCTACAGTTCAAATGTGCAAAATCTGTGGAAAACCCCTGAGTTCAACTTTGGAGTTATACGAGCACTTAAAAGCCGCTCATGCAAGGGAATTACTGGGTTACAACGCTAACCAGGGCTCCAGTAAATCACAGGATATGTCCCAAGAGATGGAACCCGATTATGAAAATGATCAGGAATCTGTCGACCCCAGCGTCGATTACCAAGCGCGCTACCCGTGCGATACTTGTGGCAAACAGTTTGTTGGATTGCTAGCGTTGCAGAACCACCAATGCATCAATCAGATTCCAGCACAACCACAGACGTTTGACTGCGAGATTTGTCATAAGAGCTACACCTCAATATCTGCGCTAAAGAGCCATAGAGGGTGGCATTTACGTTCCCCCGATGGAAAAGCAGCCGCCAATAATTCAGGCCTTTGGATGCCACAGCACAAAGTTACTAGCAAGATAAGCAAACATGAAGTTGTCGACCCGTCACAACTAGCTAAGGTCACACATACTCCCACTCCCCCTCCTGTCAGCGCTACCGCAGCGAAAAGAAGACTGCCACCGGAGGTCGAAGTAACCGTCGTAAATCCAAACAAGAAATTGCGCTCAGACGACTCTGTGGACTTGGATCAAAGTTCTGGTGCATTAGAGGATAGGTACTGTACGATTTGTGACAAGGAATTTACCAAACGAGCAGCGTATCAGCGCCACATGGACGAAGTACATCAACCGAACTCTGTGTTTTGCCCAGTTTGTGATAAGAGTTTCACTAGGAAGTCCACATTGCTTATTCACATGAAGAAACACTATGAGAGTGGTGAGGGTAGTTCCTCCGCCACAGGTCAAGGGGATGATGATTTCTCCTGTGATTTGTGTGGTGCTCAGTACGACAACGATCAGGCGTTGAGGGCGCACCGAGCGAGGCATCACGGGGAAGAGGAAGAGTCAGCAGAAGAGAGTGACGACGGTAATGTCCCTGTGGCTCCGCCCGGTGAATTCACATGTGCACAATGTGGTGATGGTGTCGCTACACCGAGGGACCTCATCGCCCATCGCACAATGCATGCTACTCCCACCAAATTTTTCTGTAACATATGTAAAGTGTACTTCGCTCGGGCGCTCGACCTCTCCTCGCACACCCGGGCGCGACACGCTGACAACGAAAAGGTGTTCTTCCCGTGTGCCATGTGCGAcagattttacatgaacaagaAAAGTTTACAGCGGCACATCGAGATGGCTCACTGA
Protein Sequence: MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLALKIKDCVSVQINENDDLPTNVCRKCMDNVNNWHVFKNVCERTQNKLLSLKDGSQLEEVKIKSEPLSDEAYDDGVVIDGSYPVIENAGFSNKVQPEGPPILASLGLTPRSDKKCVDPRMDWHRVHAILDMVQDNEVIDSLQTKEESDVLQHSDHDSETEAELQPEIDDCYVDCKSGYICKNKKVFSKIPKQSTSVHIARLKEASKLRKRKSDVRKHCSRPKNAWQLLFTDDLLELIVASTNDNIVTNGKSFTDSTSVSEIKTLIGILYLHGIMRPTHQQCSDLWNSECGVPCVRKIMKYERFKFLLQNISFDKEDDDSIIQFDIMKRMRKVFEIFAMNCRTSHEIENVAVIDEIIVPVYGPCPFRYDIDKKPLKRGIKMVLLVDSSTFYMSNLDVITDPYFGAEEITKKLVQHLAGTGRSIVMDSWYTSSTLIDSLKNEYQLFSIAALNPNSDMIPPLFLSQYRKYRTFMSAFIDDEVSLTSYVNAEGKSVNVLTNEPRYYRKGHINHTTVVSVYKKNQSAVEITDVLMNYYTTMQHTNDWTLSLFFTLLNIASVNAQVLWCSQNSNVTQRRLFIKDLALSLLEPHEERMLISPILDLEERKNKFSIVRSNAQPYYKNRRRCKICVKTTKRDRRTRQFCVKCGTFICKEHAVSGAESENNEEDEEEMNEPAQNFPKMPHMPEVSITVMRPTGETLHARQGIHQLASKLCLVCGRSYRYSHNARRHELTAHSFDRYTNKITPKKTLNHLQPKLRPNPFNPKARMMPNPISHKMQFLNKNISAKIMPMNKIITPQKPIPIKTSKTTQNNLPYPLRIKALKDLQIKKKEPQILKTLLTSKPEVLVSEPEILNSGPESPETLISEPEIASFQVEAILTEPDADAYDDPQQGDEEVDEDMQNNQSQNYDTVDMDSENEIEIARQQGDENEGEENADVDENIDHDDDNNMEGGQSDNEKDVNDDTAESQENMEEEDSVDIKAESEIKDEEEDQEDRDNEEIEMNHNENEEEDDDDLPISLAPVVEINEGLQANSFNSEVNEDDEELDETNDGDTNETLEDEEQVKELDPDKTYVTKTQRDFIQKYRDIIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFGHIGALLSHMRSNSCTNLWKIIYNENGITDDLVLEDEPKEVKVAYKDIFNARSYACKLCPAKFQLKQFIMKHVLDTHEDGQSRVPLCCVHCRSRFKDKSLLKKHIRKGDCTVYIACDLCSEKFRNLQDFNDHALAIHAGSFDQSDNQSKCVDGRPTDCPLCGKKNSSYPNLVKHLKVIHAEEKPHYCQHCDAKYEQATELNKHIYMEHSDRTLGMPPTEPDMSIVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQSHPGIGAVAATESEFFCDICIRAFKSRQAYSNHMRIHAKVPTTNRKPGVVKEGFAPQVIGKPIKQYPMVQPGFVSFKPNYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILVDRHDSEENTMQASTEEEEFNPDENGAVLTTPQFNSFNFTNFPNNAQPTTPETMPYSCELCGKRFPLKTSLWKHKRAKHGIVNPGSSGSNDTSTPSASGESSSRSSCTICRITFSDKKSYYRHRKNVHKSTVQMCKICGKPLSSTLELYEHLKAAHARELLGYNANQGSSKSQDMSQEMEPDYENDQESVDPSVDYQARYPCDTCGKQFVGLLALQNHQCINQIPAQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKISKHEVVDPSQLAKVTHTPTPPPVSATAAKRRLPPEVEVTVVNPNKKLRSDDSVDLDQSSGALEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYESGEGSSSATGQGDDDFSCDLCGAQYDNDQALRAHRARHHGEEEESAEESDDGNVPVAPPGEFTCAQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00017541;
90% Identity: iTF_00447463;
80% Identity: -