Basic Information

Insect: Cheilosia variabilis
Gene Symbol: -
Assembly: GCA_951230905.1
Location: OX579680.1:29517904-29525559[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 3.9e-05 0.0055 17.9 2.1 1 23 399 421 399 421 0.96

2 18 1e-05 0.0014 19.8 0.4 1 23 427 449 427 449 0.97

3 18 2e-05 0.0027 18.9 0.5 1 23 455 477 455 477 0.98

4 18 1.7e-05 0.0023 19.1 3.1 1 23 483 505 483 505 0.97

5 18 3.8e-05 0.0053 18.0 4.7 1 23 511 533 511 533 0.99

6 18 6.9e-05 0.0097 17.1 5.7 1 23 539 561 539 561 0.97

7 18 1.9e-07 2.7e-05 25.2 4.3 1 23 567 589 567 589 0.98

8 18 1.2e-07 1.7e-05 25.8 2.4 1 23 595 617 595 617 0.97

9 18 0.00016 0.023 16.0 5.7 1 23 623 645 623 645 0.97

10 18 2e-05 0.0029 18.8 6.5 1 23 651 673 651 673 0.98

11 18 3.4e-06 0.00048 21.2 4.5 1 23 679 701 679 701 0.98

12 18 7.9e-06 0.0011 20.1 8.1 1 23 707 729 707 729 0.98

13 18 1.9e-06 0.00027 22.0 7.9 1 23 735 757 735 757 0.98

14 18 7.2e-07 0.0001 23.4 7.7 1 23 763 785 763 785 0.98

15 18 0.00023 0.032 15.5 9.5 1 23 791 814 791 814 0.95

16 18 0.00019 0.027 15.7 0.5 1 23 820 842 820 842 0.97

17 18 0.00085 0.12 13.7 4.4 1 23 852 874 852 874 0.98

18 18 7.1e-06 0.00099 20.2 1.7 1 23 880 903 880 903 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	3.9e-05	0.0055	17.9	2.1	1	23	399	421	399	421	0.96
2	18	1e-05	0.0014	19.8	0.4	1	23	427	449	427	449	0.97
3	18	2e-05	0.0027	18.9	0.5	1	23	455	477	455	477	0.98
4	18	1.7e-05	0.0023	19.1	3.1	1	23	483	505	483	505	0.97
5	18	3.8e-05	0.0053	18.0	4.7	1	23	511	533	511	533	0.99
6	18	6.9e-05	0.0097	17.1	5.7	1	23	539	561	539	561	0.97
7	18	1.9e-07	2.7e-05	25.2	4.3	1	23	567	589	567	589	0.98
8	18	1.2e-07	1.7e-05	25.8	2.4	1	23	595	617	595	617	0.97
9	18	0.00016	0.023	16.0	5.7	1	23	623	645	623	645	0.97
10	18	2e-05	0.0029	18.8	6.5	1	23	651	673	651	673	0.98
11	18	3.4e-06	0.00048	21.2	4.5	1	23	679	701	679	701	0.98
12	18	7.9e-06	0.0011	20.1	8.1	1	23	707	729	707	729	0.98
13	18	1.9e-06	0.00027	22.0	7.9	1	23	735	757	735	757	0.98
14	18	7.2e-07	0.0001	23.4	7.7	1	23	763	785	763	785	0.98
15	18	0.00023	0.032	15.5	9.5	1	23	791	814	791	814	0.95
16	18	0.00019	0.027	15.7	0.5	1	23	820	842	820	842	0.97
17	18	0.00085	0.12	13.7	4.4	1	23	852	874	852	874	0.98
18	18	7.1e-06	0.00099	20.2	1.7	1	23	880	903	880	903	0.96

Sequence Information

Coding Sequence: atgttacaGCAACATGTccagcaacatcaacatcacGAAAACCCTGGTATTGTCGGAGTTATTCAGCCTGTTGGCGGGATCGATTCGGATGTGTccaaacaacagcagcagccgcaTCAGCATCAACTGCAACAACATCACCAGCATCAGCCATCGCTTGTATCAGGTGCCCCACATCTTGGAAAATACTGGGTTGTCACGAATCTATTCCAAGGACCAGGTCAGCCGCCATACAATATTGGTGTAACGCCAACAACCTCAGCAGTTCCTACACTACCGCCTCCAATATCATCTCATTCAAGCGCCTCAGGACCAAAATCAGGAAACTCGAAACAACAGCAAGATCAACAACTAGCTCCAAACTCGCACACACAATCGCCAGCACACATAGTCTCATCCGTCGGTGCAACGTCTCTCCAAATACCCAATCCGATGATTTCGAACGCCTCCTTGAATCAGCAGCAGCTTCCGAATGGCACAATAATTGCCGGACCACGTCATCCGGATTCCCTACACGTCCATGGAACGATGTCCTCCGACGATAATCGACACGTCTCACACGGTATGCAAGACATAAAGGAGGAGAAACCTTTTATAAATGGCAAGCAAAACAATCACATGGCTCATGTGAATCCAGCATCTTCCGTTTCGTCGAAAATGAATTCTGGCAATGGTGGCAACAATCCACAATCGGCCGAACCAGGTGGCGGTGTACAAATGGTAAACAAACTGCAAGCGGGCGGTGAACAACAAGAGCTGGGCACCGGTAAGCCGCCACACGGCGTCGAAATGTACAAAGTCAATATCGAAGATTTGAGTCAATTTCTATCATATCACGAGGTCTTTGGCAAGATCCATGGCGAAGTaataaatcaacagcaaatatcaTCGCACACGGTAACGCATCCTACTACAAATGTATCAACCTCAAATGCTGGTGGCAATACCTCTGTGAGTGGTACTGTTACTGGTTCACTACCTCCACCCCCGCCACCGTCGACAAATGGCAATTCGATAGTGACAACCAACAGCCTTACCAGTTCAGGGACGGGTGCCCAAACAGCTGCGCCGCCAGGTGGTGTACCCACCGCTACCGGCGATCTATTAATGCCCAAAATGGAGAATCAAGGAATGGGCGTCGATCAGAATACCCCACTGTTGGCACCTGACGGCACCCCCATAATGGGCGGCACGCATATCTGTGACATTTGCGgcaaaatgtttcaatttcgCTATCAACTAATTGTGCATCGTCGCTACCACAGTGAACGTAAGCCATTCAATTGCCAAGTATGCGGACAGGGATTTACAACGTCACAAGATCTCACCCGTCACGGCAAGATCCATATTGGTGGGCCAATGTTCACGTGTGTCATCTGCTTCAATGTGTTTGCCAACAACGCCAGTCTGGAACGGCATATGAAACGCCACTCGACCGATAAGCCATTCGCGTGCACCATATGCCAGAAGACATTTGCCCGCAAAGAGCATTTGGACAACCATTTTCGCAGTCATACGGGCGAGACGCCATTCCGTTGTCAGTATTGTGCGAAAACGTTTACGCGAAAGGAACACATGGTGAATCATGTGCGCAAGCATACCGGAGAGACGCCGCATCGTTGCGATATTTGTAAGAAATCTTTTACGCGGAAAGAGCACTATGTAAACCATTACATGTGGCATACAGGTCAGACGCCGCACCAATGTGACATTTGTGGGAAGAAGTACACCCGGAAGGAACATCTAGCCAATCATATGCGCTCCCATACGAACGATACACCATTCCGGTGTGAGATATGTGGCAAGAGTTTCAGCAGAAAGGAGCACTTTACCAACCACATTCTATGGCATACAGGAGAAACCCCTCATCGCTGTGATTTCTGTGCGAAGACGTTCACCAGGAAGGAGCATCTATTAAACCATGTCCGCCAACATACGGGTGAGTCTCCACATCGCTGCACCTATTGCTTGAAGACCTTCACTCGTAAGGAACACCTAGTGAATCACATTCGTCAACACACAGGCGAAACCCCCTTCAAGTGCACGTACTGTACTAAGGCGTTTACACGAAAGGATCACATGGTGAATCACATCCGTCAACATACTGGAGAGTCTCCGCATAAATGCACCTACTGCACGAAAACCTTCACAAGGAAAGAACATCTGACCAATCATGTGCGCCAACATACGGGTGAGTCGCCTCATCGTTGCACCTActgcaaaaaaacatttacacgCAAGGAACACCTAACGAATCACATCCGGTTGCATACAGGCGATTCGCCCCACAAATGCGAATACTGCCAAAAGACGTTCACACGCAAGGAGCATTTGAACAACCACATGCGACAACACTCGAGTGACAATCCGCATTGCTGTAATGTGTGCAACAAACCGTTCACACGCAAGGAACACTTGATCAATCATATGTCACGGTGTCATACAGGCGATCGGCCGTTTGCCTGTGAAACGTGCGGAAAAAGTTTTCCACTAAAAGGTAACTTGCTCTTCCATCAGCGCAGTCACACCAAGGGGCAAGAGTGTGAGCGTCCGTTTTCGTGCGAGAAGTGCCCGAAGAACTTTATTTGCAAAGGTCATCTGGTGTCGCATATGCGTTCGCATTCAGGTGAGAAACCACATGCCTGCACTATGTGCAGTAAGGCATTTGTGGAGAGAGGGAACCTCAAGCGTCACATGAAGATGAACCATCCCGATGCAGTTATGCCACCGCCGCCGACACCAATTCCGGGTATTTTGACGCAAATCAAACAGGAAATCAACCCAATAATAATTCCTCATCAACCTCCAACCATGCACACGATACAGCAAATCACTTCAACTGCAGGCAGCTCAAGTGCAACAAATCCAGTAAATCCGGCCCTTCTGGCACCCGGTCTTGTACCAATGGTAACATCTACAATAACTTCACACCTTAATCAAAAGCAGCAATcccatcaacagcagcagcagcaacaacaacaacaccaacatcAACAGCagttgcagcagcagcagcagcaacaacagcttTTACAGCTCTCCATTCAGCAGGCGGCTCAACATCAGCAGGTTGAACATcggcagcaacaacagcagcagcaacaacaacaacagcagcagcaacagcatcaacagcagcaacaacagcaaagccatcaacaacaccaacaacagcagcagcaacaacaacagcaagctCAGCAACAATCACAACAGCAATCACAGCATCAACAGCCACAACCGCCACCAGTGCCGATAGCTCTCATTGGAGCCGACCCCTCAGCGATAGCACGTGCTGCCATGCAACTACAACATTTGCCAACCAACGTCGAACAACATCCAGTGGTGTACTAG
Protein Sequence: MLQQHVQQHQHHENPGIVGVIQPVGGIDSDVSKQQQQPHQHQLQQHHQHQPSLVSGAPHLGKYWVVTNLFQGPGQPPYNIGVTPTTSAVPTLPPPISSHSSASGPKSGNSKQQQDQQLAPNSHTQSPAHIVSSVGATSLQIPNPMISNASLNQQQLPNGTIIAGPRHPDSLHVHGTMSSDDNRHVSHGMQDIKEEKPFINGKQNNHMAHVNPASSVSSKMNSGNGGNNPQSAEPGGGVQMVNKLQAGGEQQELGTGKPPHGVEMYKVNIEDLSQFLSYHEVFGKIHGEVINQQQISSHTVTHPTTNVSTSNAGGNTSVSGTVTGSLPPPPPPSTNGNSIVTTNSLTSSGTGAQTAAPPGGVPTATGDLLMPKMENQGMGVDQNTPLLAPDGTPIMGGTHICDICGKMFQFRYQLIVHRRYHSERKPFNCQVCGQGFTTSQDLTRHGKIHIGGPMFTCVICFNVFANNASLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDICGKKYTRKEHLANHMRSHTNDTPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCAKTFTRKEHLLNHVRQHTGESPHRCTYCLKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGESPHRCTYCKKTFTRKEHLTNHIRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFACETCGKSFPLKGNLLFHQRSHTKGQECERPFSCEKCPKNFICKGHLVSHMRSHSGEKPHACTMCSKAFVERGNLKRHMKMNHPDAVMPPPPTPIPGILTQIKQEINPIIIPHQPPTMHTIQQITSTAGSSSATNPVNPALLAPGLVPMVTSTITSHLNQKQQSHQQQQQQQQQHQHQQQLQQQQQQQQLLQLSIQQAAQHQQVEHRQQQQQQQQQQQQQQQHQQQQQQQSHQQHQQQQQQQQQQAQQQSQQQSQHQQPQPPPVPIALIGADPSAIARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00426545;
90% Identity: iTF_01300228; iTF_00312007; iTF_00312844; iTF_00313676; iTF_01301072; iTF_00314549; iTF_00311226; iTF_00724954; iTF_01542372; iTF_01522022; iTF_01116586; iTF_01521322; iTF_01044879; iTF_01541589; iTF_00671707;
80% Identity: -