Basic Information

Gene Symbol
-
Assembly
GCA_955612985.1
Location
OY015311.1:122340296-122355324[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 4.8e-05 0.0056 17.8 2.1 1 23 460 482 460 482 0.96
2 18 1.2e-05 0.0015 19.7 0.4 1 23 488 510 488 510 0.97
3 18 2.4e-05 0.0028 18.8 0.5 1 23 516 538 516 538 0.98
4 18 2e-05 0.0024 19.0 3.1 1 23 544 566 544 566 0.97
5 18 4.6e-05 0.0054 17.9 4.7 1 23 572 594 572 594 0.99
6 18 8.4e-05 0.0099 17.0 5.7 1 23 600 622 600 622 0.97
7 18 2.3e-07 2.7e-05 25.1 4.3 1 23 628 650 628 650 0.98
8 18 1.5e-07 1.7e-05 25.7 2.4 1 23 656 678 656 678 0.97
9 18 0.0002 0.023 15.9 5.7 1 23 684 706 684 706 0.97
10 18 2.5e-05 0.0029 18.7 6.5 1 23 712 734 712 734 0.98
11 18 4.2e-06 0.00049 21.2 4.5 1 23 740 762 740 762 0.98
12 18 9.7e-06 0.0011 20.0 8.1 1 23 768 790 768 790 0.98
13 18 2.4e-06 0.00028 21.9 7.9 1 23 796 818 796 818 0.98
14 18 8.8e-07 0.0001 23.3 7.7 1 23 824 846 824 846 0.98
15 18 0.00028 0.032 15.4 9.5 1 23 852 875 852 875 0.95
16 18 0.00023 0.027 15.7 0.5 1 23 881 903 881 903 0.97
17 18 0.001 0.12 13.6 4.4 1 23 913 935 913 935 0.98
18 18 8.6e-06 0.001 20.2 1.7 1 23 941 964 941 964 0.96

Sequence Information

Coding Sequence
ATGAATTCGGATCATACAACAGCTCCTGGCGAGTCGTCATCAAATCCGAATGACTCTCAACAAAGTCGGCATTCGCCGCAGCAGgcccagcaacaacaacaacagcagcagcatcatcagcatcaacaacaacaacaacagcagcaacaactcGCTCACCAGCGCCATCCGCAACAATTGAATGAACAACATGTccagcaacagcaacatcaaCATCACGAAAATCCTGGCATTGTCGGAGTTATTCAGCCTGTTGGCGGGATCGATTCGGATGTATCCAAACAACAGCACCAGCCGCAGCAGCATCAACTACAACAACAGCACCACCATCAGCCATCGCTTGTATCGGGTACCCCACATCTTGGAAAATACTGGGTTGTCACGAATCTATTCCAAGGCCCAGGTCAGCCGCCATACAATATTGGTGTAACGCCAACAACCTCAGCAGTTCCTACACTACCGCCTCCAATATCATCTCATTCAAGCGCCTCAGGACCAAAATCAGGAAACTCGAAACAACAGCAAGATCAACAATTAGCTCCAAACTCGCACACACAATCGCCAGCACATATAGTCTCATCCGTTGGTGCAACATCTCTCCAAATACCCAATCCAATGATCACGAATGCCTCATTGAATCAGCAGCAGCTTCCGAATGGCACCATTATTGCCGGACCACGTCATCCGGATTCCCTACACGTCCATGGAACGATGTCCTCCGACGATAATCGACACGTCTCACACGGTATGCAAGACATAAAGGAGGAGAAACCTTTCATAAATGGCAAGCAAAACAATCACATGGCTCATGTCAATCCAGCATCTTCCGTTTCGTCGAAAATGAATTCTGGCAGTGGTGGCAACAATCCGCAATCGGCGGAACCAGGTGGCGGTGTGCAAATGGTTAATAAACTGCAAGCGGGCGGTGAACAACAAGAGCTGGGCACCGGTAAGCCGCCACACGGTGTCGAAATGTACAAAGTCAATATCGAAGATTTGAGTCAATTTCTATCATATCACGAGGTCTTTGGCAAGATCCATGGCGAAGTAATAAATCAACAACAAATATCATCGCACACGGTAACGCATCCTACTACAAATGTATCAACCTCAAATGCTGGTGGCAATACCTCTGTGAGTGGTACTGTTACCGGCTCACTACCTCCACCCCCGCCACCGTCGACAAATGGCAATTCGATAGTGACAACTAACAGCCTTACCAGTTCAGGGACTGGTGCACAAGCAACAGCGCCGCCAGGTAGTGTCACCACGGCCGCCGGCGATCTATTAATGCCCAAAATGGAGAATCAAGGGATGGGCGTCGATCAGAATACACCACTATTGGCTCCCGATGGCACCCCCATAATGGGCGGTACGCATATCTGTGACATTTGTGGCAAAATGTTCCAATTTCGCTACCAACTAATTGTACATCGTCGCTACCACAGTGAACGTAAGCCATTCAATTGCCAAGTATGCGGACAGGGATTCACAACGTCGCAAGATCTCACCCGCCACGGCAAGATTCATATTGGTGGACCAATGTTCACGTGTGTCATCTGCTTCAATGTGTTTGCCAACAACGCCAGTCTGGAACGGCATATGAAACGCCACTCGACCGATAAGCCATTCGCGTGCACCATATGCCAGAAGACATTTGCCCGCAAAGAGCATTTGGACAACCATTTTCGCAGTCATACGGGCGAGACGCCATTCCGTTGTCAGTATTGTGCGAAAACGTTTACGCGAAAGGAACACATGGTGAATCATGTACGCAAGCATACCGGAGAGACGCCGCATCGTTGCGATATTTGTAAGAAATCTTTTACGCGGAAAGAGCACTATGTAAACCATTACATGTGGCATACAGGTCAGACGCCGCATCAATGTGACATTTGTGGGAAGAAGTACACTCGGAAGGAACATCTAGCCAATCATATGCGCTCCCATACGAACGATACACCATTCCGGTGCGAGATATGTGGCAAGAGTTTCAGCAGAAAGGAACACTTTACCAACCACATTTTATGGCATACAGGAGAAACCCCTCATCGCTGTGATTTCTGTGCGAAGACGTTTACCCGGAAGGAGCATCTCTTAAACCATGTTCGCCAACATACGGGTGAGTCACCACATCGCTGCACCTATTGCTTGAAGACCTTCACTCGTAAGGAACACCTAGTGAATCACATTCGTCAACACACAGGCGAAACCCCCTTCAAGTGCACCTACTGTACTAAGGCGTTTACTCGAAAGGATCACATGGTGAATCACATCCGTCAACATACTGGAGAGTCACCGCATAAATGCACGTATTGCACGAAAACCTTCACAAGGAAAGAACATCTGACCAACCATGTGCGCCAACATACGGGTGAGTCGCCTCATCGTTGCACCTACtgcaaaaaaacatttacacGCAAGGAACACCTAACGAATCACATCCGGTTGCATACAGGCGATTCGCCCCACAAATGCGAATACTGCCAAAAGACGTTTACACGCAAGGAGCACTTGAACAATCACATGCGACAACACTCGAGTGACAATCCACATTGCTGTAATGTGTGCAACAAACCGTTCACACGCAAGGAACACTTGATCAATCATATGTCACGCTGTCATACCGGAGATCGGCCGTTTGCTTGTGAAACATGCGGAAAGAGTTTCCCGCTAAAAGGTAACTTGCTCTTCCATCAGCGCAGTCACACCAAAGGACAAGAGTGTGAGCGTCCGTTTTCGTGCGAGAAATGCCCGAAGAACTTCATTTGCAAAGGTCATCTGGTGTCGCATATGCGTTCGCATTCAGGTGAAAAACCACATGCCTGCACTATGTGTAGTAAGGCATTTGTGGAAAGAGGGAACCTTAAGCGTCACATGAAGATGAATCATCCCGATGCAGTTATGCCACCGCCGCCGACACCAATTCCGGGTATTTTGACGCAAATCAAACAGGAAATCAACCCAATAATAATTCCTCATCAACCTCCAACCATGCACACGATACAGCAAATCACTTCAACTGCAGGCAGCTCAAGTAACGCAACTAATCCAGTAAATCCAGCCCTTCTGGCGCCCGGTCTTGTACCAATGGTAACATCTACAATTACTTCACACATTAATCAAAAGCAGCAATCccatcaacagcagcagcagcaacaccaACATCAGCAGCAAttgcagcaacagcagcagcaacaacaacagctttTACAGCTCTCCATTCAGCAGGCTGCTCAACATCAGCAGGCTGAACAtcgacagcaacaacaacaacaacaacagcaacaacaacagcagcaacaacaacagcagcaacagcatcaacagcagcaacaacagcagagtcatcaacaacaccaacaacaacaacagcagcagcaacagcaagctCAGCAACAATCGCAACAGCAATCACAGCATCAACAGCCACAACCGCCATCAGTGCCGATAGCTCTAATTGGAGCCGATCCCTCAGCGATAGCACGCGCTGCAATGCAATTACAACATTTGCCAACTAACGTCGAACAACATCCAGTCGTGTACTAG
Protein Sequence
MNSDHTTAPGESSSNPNDSQQSRHSPQQAQQQQQQQQHHQHQQQQQQQQQLAHQRHPQQLNEQHVQQQQHQHHENPGIVGVIQPVGGIDSDVSKQQHQPQQHQLQQQHHHQPSLVSGTPHLGKYWVVTNLFQGPGQPPYNIGVTPTTSAVPTLPPPISSHSSASGPKSGNSKQQQDQQLAPNSHTQSPAHIVSSVGATSLQIPNPMITNASLNQQQLPNGTIIAGPRHPDSLHVHGTMSSDDNRHVSHGMQDIKEEKPFINGKQNNHMAHVNPASSVSSKMNSGSGGNNPQSAEPGGGVQMVNKLQAGGEQQELGTGKPPHGVEMYKVNIEDLSQFLSYHEVFGKIHGEVINQQQISSHTVTHPTTNVSTSNAGGNTSVSGTVTGSLPPPPPPSTNGNSIVTTNSLTSSGTGAQATAPPGSVTTAAGDLLMPKMENQGMGVDQNTPLLAPDGTPIMGGTHICDICGKMFQFRYQLIVHRRYHSERKPFNCQVCGQGFTTSQDLTRHGKIHIGGPMFTCVICFNVFANNASLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDICGKKYTRKEHLANHMRSHTNDTPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCAKTFTRKEHLLNHVRQHTGESPHRCTYCLKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGESPHRCTYCKKTFTRKEHLTNHIRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFACETCGKSFPLKGNLLFHQRSHTKGQECERPFSCEKCPKNFICKGHLVSHMRSHSGEKPHACTMCSKAFVERGNLKRHMKMNHPDAVMPPPPTPIPGILTQIKQEINPIIIPHQPPTMHTIQQITSTAGSSSNATNPVNPALLAPGLVPMVTSTITSHINQKQQSHQQQQQQHQHQQQLQQQQQQQQQLLQLSIQQAAQHQQAEHRQQQQQQQQQQQQQQQQQQQQHQQQQQQQSHQQHQQQQQQQQQQAQQQSQQQSQHQQPQPPSVPIALIGADPSAIARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00426545;
90% Identity
iTF_00315368;
80% Identity
-