Alep011664.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Athetis lepigone
Gene Symbol
ham
Assembly
GCA_033675125.1
Location
CM066224.1:7771455-7808711[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.032 3.3 9.5 0.0 2 23 294 316 293 316 0.96
2 9 0.0011 0.12 14.0 0.8 1 23 323 346 323 346 0.93
3 9 2.4e-08 2.5e-06 28.7 0.1 1 23 352 375 352 375 0.96
4 9 2.1e-06 0.00021 22.7 1.7 1 23 381 403 381 403 0.95
5 9 7.3e-05 0.0076 17.8 6.1 1 23 409 431 409 431 0.99
6 9 0.00015 0.015 16.8 0.4 2 21 439 458 438 459 0.94
7 9 1.8e-08 1.8e-06 29.2 0.7 1 23 856 878 856 878 0.98
8 9 6.3e-07 6.6e-05 24.3 1.7 1 23 884 907 884 907 0.97
9 9 2.4e-05 0.0025 19.3 3.2 1 23 913 935 913 935 0.98

Sequence Information

Coding Sequence
ATGAGACAAGAAACAAATACatattgtcatacaaaatatttgtttctttcGCAAGTCGAATCTACGACAGACAACACAGGGCAGTTGCTTAGCCACTGCCCCAATCCTGCAGTCCACGTCAACCAAAGACTAATTCGAGTTATTTTGTCCACAGCAGCAGACAGCCAGGAGTCTGGCAGTCCACCGCCGAGCCCGACTGACTCTGCCACATCTGAATCAGCGCCCACCTTAGTTCACATCAAACAAGAAAACATGCCTCCTGGAACAGATGTTAAAGAGTACTATGGTACTTTAGACTTTGGTCTATCAGACACATATCTAGCCAATAACTTCCCAGAATACGGCCGGGGATACCTTCCCAGACCTCTGGACCATTTAAAATCAGTTAAAAAAGAGGATGGAACGAAGGATGATGATCCCGGGGATAGAGACTTAATTTTACCTAGTGAATTGATGTTTAAAAGTGGCGGGATATTTGCTAGAGTGAATATTGCAAATGGGACCCAGTATGGACCTTTTCTGGGAGTTTTGGAGACTCAGCCGAAGGACCGGCGGTTTGCTTGGGAGgTCCGCGACAAGAATGGCGTCAGTGGCTGGTTGGATGCCACCTCGGAGAAGGGGAACTGGCTGAAACTAGTGCGCTCAACCAACTACCCACATGACGTCAACGTACAACACCTCTTATTGGGAGGGCAGGTATGGTACAAAGTGGTTCGCGAGGTGCCCTCCGGCCAGGAGTTGTTGCTGGGTCCTCGCACTCCCATCTACTTGGAGGACATGCTCTCTCTGGACTCCGTTAGGACGAACCGTCAGTCATCTATCGAGAAGTTTAGTTCTCTGCCGTCAGCTGACGACGAGGAGAGAGAAGACGCAGACGTCCGCTGCAACATCTGCGAACTACCCTTCCCTAACATTGATGTTCTCGATCGTCACTTGATTACGGAGCACGCTCAACCTGCGGCTGCTTTTCACTGCGAACTTTGTAACAGGGCTTACAGTACTCGGGTACTACTCCTGCGACACCGTGCGCTTGCGCATACTGATATCAGAAAGTACCCCTGCGAGAACTGTCCTAAGGTATTTACCGATCCTTCCAACCTGCAGCGCCACATTCGCGCGCAGCACGCTGGTGCCCGCAGTCACGCGTGTCCTGAGTGCGGCAAGACCTTCGCCACCTCCTCCGGCCTGAAGcagcacacacacatacactccAGCGTCAAACCCTTCCAGTGCAAGGTTTGCTTTAAGGCTTACACCCAGTTCTCCAACCTCTGCCGCCACAAGCGGATGCACGTTGCTTGTCGAGCTCTCGTTGAATGCGGAAAATGCGGCCAGTCCTTCACGTCCTACGCCTCTCTTACTAAGCACAAGAGATTTTGTGACACTGCTGCCGCAGCGTCCGTCAATCTTCGAGGACAAATGCCCCAGGGCCTTCCACAAATACCATCACTTCAAAACGTCGGGATGAATAACCCTAATAACACGAACCCGTTTCCGATGTACAGGGGACCCACTCTGCCCCTCCCGTACAATACTTTTGCTCACTATCCGGCGCTGTTCTCTGCCGCCGCTGCAGCTGCTTGCCCTCCCGAGTTCCTTAGCCCACTCCTCTTCAATGTACAAGGAGCAAGACTCGCTATGGAACACGACATGGCTATGTCAAACGCCAATCTAGTATCCAAACAACAGGAAGGCCGCTTATCAGTAAAAAGCATGGACAGCTCAAACTCTTTAGATGATAACAAGAAGCCAAAAGATTTAGATTTCGAAAACAAGAGAGACAGCTACAGTTCGGACAGGGCTACGCCCAATAAGTCGCATAGTCTTTATTCTAAGCAATCACCTCCTTCTGGGGAGGAAGCCACCTCTCAACGCCGACCATCACCAGTGATGCCACTAGCCACGCCAATTGCTCCATTCAATTTCTCAAGAGATGAAATGAAGCGGAAGTCTCCGTTCAACTTCTCCCTAAAGCTCAACAATAATGACATTCAAGGTAACAAGTCTCTATCACCGCTACCTAAAGATTTGTCCAAGAATGTTGTTGAAGATGATAAAATATCCGAATATTCTGATGTTGAGGAAGACACAAAGAAAGATGAGGGTGACCAACCGTTGGACCTATCAGTGTCGAGGAAACAAAACGACAAGGATTCTGAAGCGGAAAATGATGATCGTTCTTTTCGCAACTCCGTTAAATCTTATTCACCTCCTGAAAGCCCAGCTGAGAGGAACAAGACTCCTGAAAATGACACAACAGACGTCGATGTCGAAGGCGTAGAACCTAAAAGGGAGGAATCGCCACCACAGCTTGTATCACCACCATTGGCGTTCCCCATGCCTGTCCACCCACAGCACAGCAACTTAATCGACGCCATGTACCGGCCTAGATTTCCATCATTCCACACTTCCGAATCGATTCTGAACTCATCGCACTCCCCGTATGTACCGAGCCCGTTCAATTTTTTATCCCCACTTCTCGGTACTGATGGAACTGACAGGCAACCAAGCGCGTACGCAAAGTTTCAAGAGCTAAGTGCAGGATCAGGGAAGCTGCGTGATCGGTATGCTTGCAAGTTCTGCGGGAAGGTGTTCCCGCGAAGTGCGAACTTGACTCGTCACTTACGTACCCACACTGGCGAGCAACCTTACAAGTGCAAGTACTGCGAGCGCTCGTTCTCGATCTCCTCGAACCTTCAGCGACACGTGAGGAACATCCACAACAAGGAGAGGCCATTTCGGTGTCCCTTATGTGAGAGGTGTTTCGGGCAGCAGACGAACCTTGATCGTCACTTGAAGAAGCACGAAGCTGAAGGTGGAGATTCGCCTAGTTCTGCGGATACGGAGAGGGAGGATGCGTACTTTGATGATATTCGGTCGTTCATGGGGAAGGTGACGTGTTCCCCGGGGGCCCGGTCCCCAGCGGCCACGCCCCCGCACGGGGCCCACGGAGCTCACAGCGCGCACGGCCCGCGCCCTTCGCTCGCGATCTCCACATAG
Protein Sequence
MRQETNTYCHTKYLFLSQVESTTDNTGQLLSHCPNPAVHVNQRLIRVILSTAADSQESGSPPPSPTDSATSESAPTLVHIKQENMPPGTDVKEYYGTLDFGLSDTYLANNFPEYGRGYLPRPLDHLKSVKKEDGTKDDDPGDRDLILPSELMFKSGGIFARVNIANGTQYGPFLGVLETQPKDRRFAWEVRDKNGVSGWLDATSEKGNWLKLVRSTNYPHDVNVQHLLLGGQVWYKVVREVPSGQELLLGPRTPIYLEDMLSLDSVRTNRQSSIEKFSSLPSADDEEREDADVRCNICELPFPNIDVLDRHLITEHAQPAAAFHCELCNRAYSTRVLLLRHRALAHTDIRKYPCENCPKVFTDPSNLQRHIRAQHAGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCKVCFKAYTQFSNLCRHKRMHVACRALVECGKCGQSFTSYASLTKHKRFCDTAAAASVNLRGQMPQGLPQIPSLQNVGMNNPNNTNPFPMYRGPTLPLPYNTFAHYPALFSAAAAAACPPEFLSPLLFNVQGARLAMEHDMAMSNANLVSKQQEGRLSVKSMDSSNSLDDNKKPKDLDFENKRDSYSSDRATPNKSHSLYSKQSPPSGEEATSQRRPSPVMPLATPIAPFNFSRDEMKRKSPFNFSLKLNNNDIQGNKSLSPLPKDLSKNVVEDDKISEYSDVEEDTKKDEGDQPLDLSVSRKQNDKDSEAENDDRSFRNSVKSYSPPESPAERNKTPENDTTDVDVEGVEPKREESPPQLVSPPLAFPMPVHPQHSNLIDAMYRPRFPSFHTSESILNSSHSPYVPSPFNFLSPLLGTDGTDRQPSAYAKFQELSAGSGKLRDRYACKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFRCPLCERCFGQQTNLDRHLKKHEAEGGDSPSSADTEREDAYFDDIRSFMGKVTCSPGARSPAATPPHGAHGAHSAHGPRPSLAIST