Hamb016838.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hoplodrina ambigua
Gene Symbol
ham
Assembly
GCA_949774945.1
Location
OX458980.1:5722165-5764812[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.13 9.8 7.5 0.0 2 23 247 269 246 269 0.96
2 9 0.001 0.076 14.1 0.8 1 23 276 299 276 299 0.93
3 9 2.2e-08 1.6e-06 28.8 0.1 1 23 305 328 305 328 0.96
4 9 1.9e-06 0.00014 22.7 1.7 1 23 334 356 334 356 0.95
5 9 6.7e-05 0.0049 17.8 6.1 1 23 362 384 362 384 0.99
6 9 0.00013 0.01 16.9 0.4 2 21 392 411 391 412 0.94
7 9 1.6e-08 1.2e-06 29.2 0.7 1 23 809 831 809 831 0.98
8 9 5.7e-07 4.2e-05 24.3 1.7 1 23 837 860 837 860 0.97
9 9 2.2e-05 0.0016 19.4 3.2 1 23 866 888 866 888 0.98

Sequence Information

Coding Sequence
ATGAAGATGTCTGCAGCAGACAGCCAGGAGTCTGGCAGTCCTCCACCGAGCCCGACTGACTCTGCCACATCAGAATCAGCGCCCACCTTAGTTCACATCAAGCAAGAAAATATGCCTCCAGGAACAGATGTTAAAGAGTACTACGGTACTCTAGACTTTGGGCTATCAGACACATATCTAGCCAATAACTTCCCAGATTACGGACGGGGATATCTATCTAGACCTCTAGAccatttaaaatcggttaaaaaaGAGGATGGGACGAAAGATGACGATCCCGGAGACAGAGATTTCATTTTACCAAGTGAATTGATGTTTAAAAATGGAGGGATATTTGCTAGAGTGAATATTGCTAATGGAACTCAATATGGACCTTTCCTGGGACTATTGGAGAATCAGCCGAAGGACAGGCGATTTGCTTGGGAGGTTCGTGACAAGAATGGTGTCAGTGGCTGGTTGGACGCCACCACAGAGAAAGGCAACTGGCTGAAAATGGTGCGCTCCACCAACTACCCCCATGATGTCAACGTACAACACCTCTTGTTGGCAGGACAGGTGTGGTACAAGGTGGTCCGTGAGGTGCCCTCCGGCCAGGAGTTGCTGCTGGGTCCTCGGACTCCTATCTACTTGGAGGACATACTCTCTTTGGACTCAGTCAGGACAAACCGTCAGTCGTCTATCGAGAAGTTCAGTTCTCTAGCGTCAGCAGATGACGAAGAGAGAGAGGACGCTGACATCCGCTGCAGCTTCTGCGAACTACCTTTTCCTAATATCGATGTTCTCGATCGTCACTTGATAACGGAGCACGCCCAGCCGGCCGCTGCATTTCATTGCGAACTCTGTAACAGAGCTTACAGCACTCGGGTACTGCTCCTGCGACACCGTGCGCTTGCGCATACAGACATCAGAAAGTACCCCTGCGAGAATTGTCCTAAGGTATTTACCGATCCTTCCAACCTCCAGCGCCACATTCGCGCGCAGCACGCGGGCGCCCGCAGTCACGCGTGTCCCGAATGCGGCAAGACCTTCGCCACCTCCTCCGGCCTGAAGCAGCACACCCACATACACTCCAGCGTCAAGCCCTTCCAGTGCAAAGTTTGCTTCAAGGCTTACACCCAGTTCTCCAACCTCTGCCGTCACAAGCGGATGCACGTCGCTTGCAGAGCACTTGTTGAATGCGGAAAATGCGGTCAGTCTTTCACGTCCTACGCGTCTCTTACTAAGCACAAGAGATTCTGTGACACCGCTGCCGCAGCTTCTGTCAATCTTCGAGGGCAAATGCCCCAGGGCCTACCGCAAATACCATCACTACAAAACGTCGGGATGAATAACCCTAACAACTCGAATCCGTTCCCGATGTACAGGGGACCCACCCTGCCCCTGCCATACAATACGTTTGCTCACTATCCGGCGCTGTTCTCTGCCGCCGCTGCCGCCGCCTGCCCACCCGAGTTCCTTAGCCCATTGCTTTTCAACGTACAAGGGGCGAGACTCGCTATGGAACATGACATGGCCATGTCAAATGCCAATTTAGTATCCAAGCAACAGGAAGGCCGCTTATCAGTAAAAAGCATGGACAGCTCAAACTCTTTAGATGATAACAAGAAGCCTAAAGATTTGGATTTCGAAAACAAAAGGGACAGCTACAGTTCAGACAGGGCCACGCCCAATAAGTCACATAGTCTTTATTCTAAGCAATCACCTCCTTCTGGGGAGGAAGCATCTTCTCAACGCCGACCGTCACCAGTGATGCCACTGCCTACACCGATTGCTCCATTCAGTTTCTCAAGAGACGAAATGAAGCGGAAGTCTCCGTTCAACTTCTCTCTCAAGCTCAATAATAATGACATTCAAGGTAATAAGTCTCTATCACCATTACCTAAAGACTTGTCCAAGAATGTCGTCGAAGAGGATAAAATTTCCGAATATTCTGATGTTGAGGAAGACACAAAGAAAGATGAGGGTGACCAGCCTTTGGATCTATCAGTATCAAGAAAACAAAACGATAAGGATTCAGAAGCAGAAAATGACGATCGTTCCTTTCGCAACTCAGTCAAATCGTATTCACCTCCTGAAAGCCCAATTGAGAGGAGCAAGACTCCCGAAAATGACACGACAGACGTCGACGTCGAAGGCGTAGAACCTAAAAGAGAGGAATCGCCCCCGCAGCTTGTATCACCACCATTGGCGTTCCCTATGCCTGTTCACCCGCAGCACAGCAACTTAATCGATGCCATGTACCGGCCCCGATTCCCATCTTTCCACACTTCCGAATCGATCCTGAACTCGTCCCACTCTCCGTATGTTCCGAGTCCATTCAATTTTTTATCCCCACTTCTCGGTACTGATGGACCTGACAGGCAACCAAGCGCGTATGCCAAGTTTCAAGAGCTTAGCGCAGGATCAGGAAAGCTGCGTGACCGGTACGCTTGCAAGTTCTGCGGAAAAGTATTCCCGCGGAGTGCGAACTTGACTCGTCATCTACGTACACACACTGGCGAGCAACCTTACAAGTGCAAGTACTGCGAGCGCTCGTTCTCAATCTCGTCGAACCTTCAGCGGCACGTGAGGAACATTCACAACAAGGAGAGGCCATTTCGGTGTCCTTTGTGCGAAAGATGCTTCGGGCAGCAGACGAATCTCGATCGTCACTTGAAGAAGCACGAAGCGGAAGGTGGAGATTCACCTAGCTCTGCGGATACAGAGAGGGAGGATGCGTATTTTGATGATATTCGGTCATTCATGGGTAAGGTGACGTGTTCCCCGGGCACGCGCTCCCCGGCGGCGACGCCCCCGCACGGGGCGCATGGAGCGCACGCTGCGCACGGTGCACACGGCGCGCATGGCCCGCGCCCTTCGCTGGCTATCTCCACATAG
Protein Sequence
MKMSAADSQESGSPPPSPTDSATSESAPTLVHIKQENMPPGTDVKEYYGTLDFGLSDTYLANNFPDYGRGYLSRPLDHLKSVKKEDGTKDDDPGDRDFILPSELMFKNGGIFARVNIANGTQYGPFLGLLENQPKDRRFAWEVRDKNGVSGWLDATTEKGNWLKMVRSTNYPHDVNVQHLLLAGQVWYKVVREVPSGQELLLGPRTPIYLEDILSLDSVRTNRQSSIEKFSSLASADDEEREDADIRCSFCELPFPNIDVLDRHLITEHAQPAAAFHCELCNRAYSTRVLLLRHRALAHTDIRKYPCENCPKVFTDPSNLQRHIRAQHAGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCKVCFKAYTQFSNLCRHKRMHVACRALVECGKCGQSFTSYASLTKHKRFCDTAAAASVNLRGQMPQGLPQIPSLQNVGMNNPNNSNPFPMYRGPTLPLPYNTFAHYPALFSAAAAAACPPEFLSPLLFNVQGARLAMEHDMAMSNANLVSKQQEGRLSVKSMDSSNSLDDNKKPKDLDFENKRDSYSSDRATPNKSHSLYSKQSPPSGEEASSQRRPSPVMPLPTPIAPFSFSRDEMKRKSPFNFSLKLNNNDIQGNKSLSPLPKDLSKNVVEEDKISEYSDVEEDTKKDEGDQPLDLSVSRKQNDKDSEAENDDRSFRNSVKSYSPPESPIERSKTPENDTTDVDVEGVEPKREESPPQLVSPPLAFPMPVHPQHSNLIDAMYRPRFPSFHTSESILNSSHSPYVPSPFNFLSPLLGTDGPDRQPSAYAKFQELSAGSGKLRDRYACKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFRCPLCERCFGQQTNLDRHLKKHEAEGGDSPSSADTEREDAYFDDIRSFMGKVTCSPGTRSPAATPPHGAHGAHAAHGAHGAHGPRPSLAIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00441779;
90% Identity
iTF_00177403;
80% Identity
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