Basic Information

Insect: Drosophila pseudoobscura
Gene Symbol: VEZF1
Assembly: GCA_009870125.2
Location: CM020868.1:21370587-21375147[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0021 0.16 12.6 1.1 1 23 216 238 216 238 0.96

2 26 0.034 2.5 8.9 1.7 1 23 244 266 244 266 0.97

3 26 0.052 3.9 8.3 2.2 2 23 298 319 297 319 0.96

4 26 0.0027 0.2 12.3 2.8 1 23 392 415 392 415 0.94

5 26 2.2 1.7e+02 3.2 1.1 2 22 423 443 422 443 0.94

6 26 0.56 42 5.0 1.5 1 23 452 474 452 474 0.97

7 26 0.17 13 6.6 0.2 3 23 486 506 484 506 0.96

8 26 0.008 0.6 10.8 2.0 1 23 589 612 589 612 0.97

9 26 0.032 2.4 8.9 0.1 2 22 622 642 622 642 0.94

10 26 0.3 23 5.9 4.8 1 23 651 674 651 674 0.96

11 26 0.0012 0.09 13.4 1.6 2 23 700 721 699 721 0.97

12 26 1.3e-05 0.001 19.6 2.8 1 23 729 751 729 751 0.99

13 26 0.005 0.38 11.5 0.9 1 23 903 926 903 926 0.94

14 26 0.011 0.81 10.4 0.5 2 22 934 954 933 954 0.95

15 26 0.043 3.2 8.5 0.6 1 23 963 986 963 986 0.90

16 26 1.9e-05 0.0014 19.1 1.2 2 23 1007 1028 1006 1028 0.97

17 26 0.00017 0.013 16.1 0.8 1 23 1035 1057 1035 1057 0.98

18 26 0.031 2.4 9.0 0.0 2 21 1084 1103 1083 1104 0.93

19 26 0.013 0.95 10.2 3.9 1 23 1150 1173 1150 1173 0.96

20 26 0.0071 0.54 11.0 0.5 1 23 1210 1233 1210 1233 0.96

21 26 0.00031 0.023 15.3 1.5 1 23 1257 1280 1257 1280 0.97

22 26 5.8e-06 0.00044 20.7 0.2 2 23 1306 1327 1305 1327 0.95

23 26 0.00016 0.012 16.2 2.9 1 23 1333 1355 1333 1355 0.99

24 26 3.9e-06 0.00029 21.3 2.0 1 23 1361 1383 1361 1383 0.97

25 26 5.8e-08 4.4e-06 27.0 2.4 1 23 1389 1411 1389 1411 0.99

26 26 0.0014 0.1 13.2 0.1 1 21 1417 1437 1417 1441 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0021	0.16	12.6	1.1	1	23	216	238	216	238	0.96
2	26	0.034	2.5	8.9	1.7	1	23	244	266	244	266	0.97
3	26	0.052	3.9	8.3	2.2	2	23	298	319	297	319	0.96
4	26	0.0027	0.2	12.3	2.8	1	23	392	415	392	415	0.94
5	26	2.2	1.7e+02	3.2	1.1	2	22	423	443	422	443	0.94
6	26	0.56	42	5.0	1.5	1	23	452	474	452	474	0.97
7	26	0.17	13	6.6	0.2	3	23	486	506	484	506	0.96
8	26	0.008	0.6	10.8	2.0	1	23	589	612	589	612	0.97
9	26	0.032	2.4	8.9	0.1	2	22	622	642	622	642	0.94
10	26	0.3	23	5.9	4.8	1	23	651	674	651	674	0.96
11	26	0.0012	0.09	13.4	1.6	2	23	700	721	699	721	0.97
12	26	1.3e-05	0.001	19.6	2.8	1	23	729	751	729	751	0.99
13	26	0.005	0.38	11.5	0.9	1	23	903	926	903	926	0.94
14	26	0.011	0.81	10.4	0.5	2	22	934	954	933	954	0.95
15	26	0.043	3.2	8.5	0.6	1	23	963	986	963	986	0.90
16	26	1.9e-05	0.0014	19.1	1.2	2	23	1007	1028	1006	1028	0.97
17	26	0.00017	0.013	16.1	0.8	1	23	1035	1057	1035	1057	0.98
18	26	0.031	2.4	9.0	0.0	2	21	1084	1103	1083	1104	0.93
19	26	0.013	0.95	10.2	3.9	1	23	1150	1173	1150	1173	0.96
20	26	0.0071	0.54	11.0	0.5	1	23	1210	1233	1210	1233	0.96
21	26	0.00031	0.023	15.3	1.5	1	23	1257	1280	1257	1280	0.97
22	26	5.8e-06	0.00044	20.7	0.2	2	23	1306	1327	1305	1327	0.95
23	26	0.00016	0.012	16.2	2.9	1	23	1333	1355	1333	1355	0.99
24	26	3.9e-06	0.00029	21.3	2.0	1	23	1361	1383	1361	1383	0.97
25	26	5.8e-08	4.4e-06	27.0	2.4	1	23	1389	1411	1389	1411	0.99
26	26	0.0014	0.1	13.2	0.1	1	21	1417	1437	1417	1441	0.91

Sequence Information

Coding Sequence: ATGCTGCCTAGCAATATTTGCCGCACGTGTGCCCTGCAAAACAGCAATTTGCTGCCCCTCTCCACTTCCTTGGACAAGTACACGAATAAAAGTTTCTATGATGTGCTCCAAGAGCTGACACAGATCGATCCCCTGCTGGAGAATGCTGACGACAATCTGCCCCAGCATCTGTGCGTAGATTGCTTGGACAGGCTGGAGAACGCCTACGCCTTTGTGGAGCAGGCCAGAAAAGTCAATGGAGAGCTGCTGGTGCGGCTGCGGGAATGTCTGGAGGAGACCCCCATTGACATACCACAGCAGCAGATTAAAACAGAGATCGACATTGACGAGGAGCAAAGAGATTTTAGCGATTCTGGAGAGGCACAGAGGTCGTCCGACGTGGATGTGGAGTCGGCTGGCGTGTGCTCCGTTGAGCTGAAATGGACACCAGAAAGTGCCAGCGAGGATGAGAATGCCGCCGATGCACACTCAAACGATGAAGATGATGATTTGGATGAGCAGCAGCCATATATATTGCGGCGAAGTCCCCGTAAAGTCAAGCTACAGGCAGACAGTGAAGAGGAGGTCAGTACTTCAACCAACAAGCGGCGACGTGGACGTCCTCCTGGTCTGGCCAAAAGCCAGTCAAGGAATTCCGAAGGCCGTCATGCTTGTGAGGTGTGTGGCAAAACGTTTTCCTGGTTCCGGGACATGAAGCGTCACGCTCGCATTCATTACGAGAAGGCCTCGTTCGTCTGCGACACCTGTGGCAAGGGCTTTCTACGCAAGGATAAATACACGTTCCATCTGCGCTCCCACGAGAAGCGGGAGGCCAAGTGCCAGGCCCTCCAGCTGAAGAACGAGTGGAGATACGCGGAGCGTTTGTACAGCTCCGGGCGACTGAAGAGAATACAGTGCAAATTGTGTGGCTTTAAGTGCCAGCGCATGCAGGAGCTCCGATCCCATTTAGCGAGTCACGTCCGCGGGGATAGTTTGTTTAGTCTGCGAGCGGACAACGATGTGGTCAAAGAACATTTTGCCAGTGTGCCATTTGACCTGGAAAAGATCAAGCAGCAAATTTGCTCGGAAATTGCCGAAGGGCAGATGGAAAAGTACTCTTCTGTGGTCAATTTCCATGGCTACGAGCTGTGCCTGAGCGATTCTGACGATGAGCCTGCCGGTGGAGACCCACCGTACCATTGTGACCTGTGCAATCTGTCGTACACACGCAAATACCGCCTGATGCGGCACACCCTGGAGGAGCACACCCAATCGCCCATTCCCCTGCGGTGCAACCTCTGCAAAGTgggttttgtgtgtgcaaAGCTCTTTGAACAGCACCAGCGGACCCAGTGCCAGAGCAAAGTGAAGCGCTATCGTTGCCGCAAGTGTCCGGGGAAGTTCATGTGGCTGGAGAACCTTGAGCGGCATGCCTGCTCCCATCGCAAGGAGGAGCAGTCATACAGGCAAATCATCTGTTGCTTGTGCGATGCCCAGCTTCCCAGCTTAAGGCAGCTGCGCGCTCACCTGGCCACCCATCGACATGGATTGAGTGGCATTGATCCGGAGCAGAATTCTGCCTTCTTTCGTTCTTACTATCCCAACGGATTGGACAGCAGCCTCTCCGAGCTGAGCACCCGCATAGCGGGGGACTATGAGACCCAGGACTTTGGACGCTACTACAATGCCTGCACGGGAAGTGGTCAAGAGCTGGATCTCTTTGACTCCGACACGGAGGAGAGCGATGCAGACGCAGACAAAACGGAGGAAAAACAGAATCCCTGCCACACCTGCCTCCTGTGTGGAGAGACTACCACTCGGCTGCTCAAGCTGCTGCAACATCAAAGGAGACTTCACTCCGAAGAGGGCACCACGTACCCCCGCTCTTGCCAGGATTGCGGCGCTGGCTTCGTCTCGGACCCTTTGCTTCAGCAACATCGCAGACGTTCCTGTGCCAAAAAGCACTCGAAATACCACTGCCAGCGATGCAATCTTCATTTTGTGTGGCAATCGAACTACGAGCAGCACCTGCGATTGTACCACGACAAGGATGAGGATCAGGAGCAGTCGGAGGACTGCCAGCGGGGTAGAAAACATAAATCTTCGGCCGCCAAGCTTCAGTGCGATGAATGTGAAAAGGTCTTCATTTGGCACAAGGATCTCACCCGTCACAAGCGCATGCATCGCCCCCCGTCTGCAGCCCAATACGAGTGCGCCTTTTGCGACCGCAAGTTCCACCGCAAGGATGGCCTCAAGTCCCACATGCGGGTGCACAGCGAGCAGCATCAGGAGACTGTGAATGAGGAGCAGCCTTGCGTCCAATCGAACTCTACGAACAGTATTCAGAGAATGCCAGGGGAGCAGCTGGCCCAACTATGCCGTCCAAATGGCTGCAAGCAAATCCAGTGCATGATTTGCCTCTCGCGCCACTCGAAGATCTCCGATCTGAGGAATCACCTAAGCGCGCACCAATATAGCGTGTGCTTTCCACAGGAGAGAGATATTCCCAGTGCCTCGCGTTCGTTCTATCCGGAGCTGGGCACTGCCCTGGATAAACAAGAGCTGGCGGAGAGGATCATGAGCGATGTGGCCGGCGGCTTAGAGTTGGAGCGTTTTATTTCCATAACCAACGAGGCTGGCCTTGAGCTCTCGCTGGAGAGCAGTGAAACGGAAACGGATTCAGAGCAGGAGGATGACGAGAGCTCCGAGGAAGCTGACCAGCAGCGGTACGCCTGCAAAATCTGCCAGGTGGAGGTGAGGCGAAAGCATCAATTGTATGCCCACCAGCTGGAGCAACACCAGTGGGAGGAGGCTTCGCTTGTGTGTGCCCACTGTCAGGCGAGGTTCGTGAGTGAGACGCTGCTGGAGCATCACTACAGGACCCTCTGTCGGAACCCGCAGAAGCGTTTCCAGTGCCGAAAGTGCCCGCTCCGGTTCCGCTGGCGGGAGAACCTGAAGCTGCACGCCAGTGCCTCGCATCAGCAAAGAGGGCAGCCGCCAGCTGCAGAGGAACCCAGCATCCAGGCCGAGTTCGACCTCCAGTGCGGGGAGTGCAATCGCAGCTTCAAGATGCAGAAGGATCTCACGCGGCACACGCTGATGCATGCCCAGGAATCCAGCATATATCGCTGTCTTTGGTGCGCGCGCCGCTTCTATAGGAAGGCCAATCTCTTGCAGCACATTGAGCGGCACGGCATCGGAGCTAGCCAGCTGCCCTACGCGGAAGCCCTCCTCAGTGCCTATGGCCAAGCCAATGGCCAGAAGAGCGTGGAGTGCAAAGTGTGCAGCTTGAGCTTCCCCAGCATTGCTGCCCTTCGCGTCCATCTGGAGACCACGGCGTCGGGCAGTCACCACGAGCTCTCGTCCCTGCAGAACTACTCGATAACCAACCAAATGGGATTCGAGCTGCACTTGGACGATTCAGAGACGGACGAGGAGGAGTCCAAGCCACCGGGCACGCCAGCTCTCTACACCTGTGGCATGTGCCAGCTCCGGTGTGTGCGGAAGTACGAGctgcatcagcaccagcaggcCATGCACAGGCTGGAGAAGATCCCCGACGGCTGCGATCAGTGCATTTTCAAGAGTGTCTCTCCCGATCTTATCGCGCATCACAAGCGAGTGCAGTGCCACAACCGGGAGAAGCAGTTCACCTGCGCCAAATGCGGCTACAAGTTCATGTGGGAGTCCAATCtcctgctgcacatgcagctgcagcacggGAAGACCGAAGAACAGGAAGATCCACCCCTGGATGAGCCCGCGGAGCAGAAAGCTGTGTGTCCAATCTTTCAGTGCGGCCTCTGCCCGAGGAAATACAATCGCAAAGACCGGCTGACGGCCCATGTGAAGAAGTTCCACAACCCAGTGGGAGGGACTCCGAGCGCCGTACGGGCTCCCATCCGGCCAACGTCGCCCAAGGAGCCGAAACGCTTCCTTTGCGCCTTCTGTGGCAAGGCCGTgagctcctcctccaaccTCATCATCCACATGCGTCGGCACACGGGCGAGAAGCCTTTCAAGTGCGACTACTGCGAAATGGCCTTTCCGCGCTCCTCCGATCTCCAGTGCCATCGCCGGACGCACACCGGAGAGCGGCCCCATATCTGCACCGTCTGCCAGAAGGGCTTCGCCAGATCCTAcaaactgcagcagcacaTGCGCATCCACAATGGCGAGCGGCCCTACAAGTGCACCTACTGCGACAAGAGCTTCACCCAGTCAAACGACCTGACGCTCCACATTCGGCGCCACACTGGCGAGCGTCCCTATCAGTGCGGGGTCTGTGGCGAGCGTTTTATCCAGGGCACGGCCCTGAAGAATCATCGCCTGCAGCAGGGCCACTATGACGAGGCCAGCCAAGGAGCTGCAGAGTCCTCAAGGCGCACGGTCCTAGAGCAATTTACGGTATAG
Protein Sequence: MLPSNICRTCALQNSNLLPLSTSLDKYTNKSFYDVLQELTQIDPLLENADDNLPQHLCVDCLDRLENAYAFVEQARKVNGELLVRLRECLEETPIDIPQQQIKTEIDIDEEQRDFSDSGEAQRSSDVDVESAGVCSVELKWTPESASEDENAADAHSNDEDDDLDEQQPYILRRSPRKVKLQADSEEEVSTSTNKRRRGRPPGLAKSQSRNSEGRHACEVCGKTFSWFRDMKRHARIHYEKASFVCDTCGKGFLRKDKYTFHLRSHEKREAKCQALQLKNEWRYAERLYSSGRLKRIQCKLCGFKCQRMQELRSHLASHVRGDSLFSLRADNDVVKEHFASVPFDLEKIKQQICSEIAEGQMEKYSSVVNFHGYELCLSDSDDEPAGGDPPYHCDLCNLSYTRKYRLMRHTLEEHTQSPIPLRCNLCKVGFVCAKLFEQHQRTQCQSKVKRYRCRKCPGKFMWLENLERHACSHRKEEQSYRQIICCLCDAQLPSLRQLRAHLATHRHGLSGIDPEQNSAFFRSYYPNGLDSSLSELSTRIAGDYETQDFGRYYNACTGSGQELDLFDSDTEESDADADKTEEKQNPCHTCLLCGETTTRLLKLLQHQRRLHSEEGTTYPRSCQDCGAGFVSDPLLQQHRRRSCAKKHSKYHCQRCNLHFVWQSNYEQHLRLYHDKDEDQEQSEDCQRGRKHKSSAAKLQCDECEKVFIWHKDLTRHKRMHRPPSAAQYECAFCDRKFHRKDGLKSHMRVHSEQHQETVNEEQPCVQSNSTNSIQRMPGEQLAQLCRPNGCKQIQCMICLSRHSKISDLRNHLSAHQYSVCFPQERDIPSASRSFYPELGTALDKQELAERIMSDVAGGLELERFISITNEAGLELSLESSETETDSEQEDDESSEEADQQRYACKICQVEVRRKHQLYAHQLEQHQWEEASLVCAHCQARFVSETLLEHHYRTLCRNPQKRFQCRKCPLRFRWRENLKLHASASHQQRGQPPAAEEPSIQAEFDLQCGECNRSFKMQKDLTRHTLMHAQESSIYRCLWCARRFYRKANLLQHIERHGIGASQLPYAEALLSAYGQANGQKSVECKVCSLSFPSIAALRVHLETTASGSHHELSSLQNYSITNQMGFELHLDDSETDEEESKPPGTPALYTCGMCQLRCVRKYELHQHQQAMHRLEKIPDGCDQCIFKSVSPDLIAHHKRVQCHNREKQFTCAKCGYKFMWESNLLLHMQLQHGKTEEQEDPPLDEPAEQKAVCPIFQCGLCPRKYNRKDRLTAHVKKFHNPVGGTPSAVRAPIRPTSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDYCEMAFPRSSDLQCHRRTHTGERPHICTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRLQQGHYDEASQGAAESSRRTVLEQFTV*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00574973; iTF_00471781; iTF_00601189; iTF_00515025; iTF_00603494; iTF_00484574; iTF_00473936;
90% Identity: iTF_00574973; iTF_00473936; iTF_00484574; iTF_00517866;
80% Identity: -