Basic Information

Insect: Drosophila subsilvestris
Gene Symbol: VEZF1
Assembly: GCA_035043285.1
Location: JAWNNB010002045.1:1368953-1373567[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.02 1.5 9.6 1.5 1 23 217 239 217 239 0.94

2 25 0.0091 0.66 10.7 1.1 1 23 245 267 245 267 0.97

3 25 0.067 4.8 7.9 1.8 2 23 299 320 298 320 0.96

4 25 0.00067 0.049 14.2 3.1 1 23 394 417 394 417 0.94

5 25 3.4 2.4e+02 2.6 1.3 2 22 425 445 424 445 0.95

6 25 0.56 41 5.0 1.5 1 23 454 476 454 476 0.97

7 25 0.21 15 6.4 0.4 3 23 488 508 486 508 0.96

8 25 0.047 3.4 8.4 0.7 1 23 589 612 589 612 0.96

9 25 0.011 0.76 10.5 0.1 2 22 622 642 619 642 0.90

10 25 0.3 22 5.9 4.8 1 23 651 674 651 674 0.96

11 25 0.0012 0.086 13.4 1.6 2 23 700 721 699 721 0.97

12 25 0.0028 0.2 12.3 1.5 1 23 891 914 891 914 0.94

13 25 0.0092 0.66 10.7 0.3 2 22 922 942 921 942 0.95

14 25 0.043 3.1 8.5 0.6 1 23 951 974 951 974 0.90

15 25 1.9e-05 0.0014 19.1 1.2 2 23 998 1019 997 1019 0.97

16 25 0.00015 0.011 16.3 1.2 1 23 1026 1048 1026 1048 0.98

17 25 0.0051 0.37 11.5 0.0 2 22 1075 1095 1074 1095 0.94

18 25 0.011 0.78 10.4 3.7 1 23 1141 1164 1141 1164 0.96

19 25 0.036 2.6 8.8 0.5 1 23 1201 1224 1201 1224 0.95

20 25 0.00031 0.022 15.3 1.5 1 23 1249 1272 1249 1272 0.97

21 25 5.8e-06 0.00042 20.7 0.2 2 23 1298 1319 1297 1319 0.95

22 25 0.00016 0.012 16.2 2.9 1 23 1325 1347 1325 1347 0.99

23 25 3.9e-06 0.00028 21.3 2.0 1 23 1353 1375 1353 1375 0.97

24 25 2e-07 1.5e-05 25.3 2.4 1 23 1381 1403 1381 1403 0.99

25 25 0.0014 0.099 13.3 0.1 1 21 1409 1429 1409 1433 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.02	1.5	9.6	1.5	1	23	217	239	217	239	0.94
2	25	0.0091	0.66	10.7	1.1	1	23	245	267	245	267	0.97
3	25	0.067	4.8	7.9	1.8	2	23	299	320	298	320	0.96
4	25	0.00067	0.049	14.2	3.1	1	23	394	417	394	417	0.94
5	25	3.4	2.4e+02	2.6	1.3	2	22	425	445	424	445	0.95
6	25	0.56	41	5.0	1.5	1	23	454	476	454	476	0.97
7	25	0.21	15	6.4	0.4	3	23	488	508	486	508	0.96
8	25	0.047	3.4	8.4	0.7	1	23	589	612	589	612	0.96
9	25	0.011	0.76	10.5	0.1	2	22	622	642	619	642	0.90
10	25	0.3	22	5.9	4.8	1	23	651	674	651	674	0.96
11	25	0.0012	0.086	13.4	1.6	2	23	700	721	699	721	0.97
12	25	0.0028	0.2	12.3	1.5	1	23	891	914	891	914	0.94
13	25	0.0092	0.66	10.7	0.3	2	22	922	942	921	942	0.95
14	25	0.043	3.1	8.5	0.6	1	23	951	974	951	974	0.90
15	25	1.9e-05	0.0014	19.1	1.2	2	23	998	1019	997	1019	0.97
16	25	0.00015	0.011	16.3	1.2	1	23	1026	1048	1026	1048	0.98
17	25	0.0051	0.37	11.5	0.0	2	22	1075	1095	1074	1095	0.94
18	25	0.011	0.78	10.4	3.7	1	23	1141	1164	1141	1164	0.96
19	25	0.036	2.6	8.8	0.5	1	23	1201	1224	1201	1224	0.95
20	25	0.00031	0.022	15.3	1.5	1	23	1249	1272	1249	1272	0.97
21	25	5.8e-06	0.00042	20.7	0.2	2	23	1298	1319	1297	1319	0.95
22	25	0.00016	0.012	16.2	2.9	1	23	1325	1347	1325	1347	0.99
23	25	3.9e-06	0.00028	21.3	2.0	1	23	1353	1375	1353	1375	0.97
24	25	2e-07	1.5e-05	25.3	2.4	1	23	1381	1403	1381	1403	0.99
25	25	0.0014	0.099	13.3	0.1	1	21	1409	1429	1409	1433	0.91

Sequence Information

Coding Sequence: ATGCTGCCCAGCAATATTTGCCGTACGTGTGCCCTGCACAGCAACAACTTGCTGCCCCTGTCCACTTCCTTGGACAAGTATAcgcacaaaagtttttatgATGTGCTCCAAGAACTGACGCAGATCGATCCCCTGCTGGAGAATGCTAACGACAATCTGCCCCAGCATCTGTGCACAGATTGCTTGGACAGGCTAAAGGACGCGTACGCTTTTGTGGAGCAGGCCAGAAAAGTCAATGGAGAGCTGCTGGTGCGGCTGCAGGAATGTCTGGAGGAGAGCCCCATTGACATACCACAGCGGGAGATTAAAGCAGAGATCGACATTGATGAAGAGCAAAAGTATTTCACGGATTCTGGAGAGGCACAGAGAGTGtctgatgtggatgtggagtCGGCTGGCGCGTGCTCTGTTGAGTTCAAATGGACGCCAGAAAGTAACAGCGAGGATGAAAATGCACAATCAAACGAAGAAGATGACGACTATgtggatgagcagcagcagcagccctatGCCTTGCGACGAAGTTCCCGCAAGGTCAAGCCACAGGCGGATAGTGAAGAGGAGGAAGTGTTAGTGTCACCCAACAAGCGGCGTCGCGGACGTCCTCCGGGTCTGGCCAAAAGCAAGTCAAGGAATTCCGAAGGTCGTCATGCCTGTGAGGTGTGCAACAAAACGTTTTCCTGGTTCCGAGACATGAAGCGACACGCTCGCGCCCATTACGAGAAGGCCTCCTTCGTCTGTGACATCTGTGGCAAGGGATTCCTGCGCAAGGACAAGTACACGTTCCACCTGCGCTCCCACGAGAAGCGAGAGGCCAAGTGCCAGGCCCTCCAGCTGAAGAACGAGTGGAGATACGCCGAGCGTTTGTACAGCTCCGGGCGACTAAAGCGCATACAATGCAAACTGTGTGGCCTGAAATGCCAGCGAATGCAGGAGCTGCGATCCCATTTGGTGAGTCACAGTCGCACGGATAGTTTGACCACTCTGCGTGCGGACAGCGATGTGGTCAAGGAACATTTTGTCAGTGTGCTGCCACTTGACCTGGAAAAGATCAGGCAGCGGGTGTGCACGGAAATAGCCGAAGGGCAGCTGGAAAAGTACTCGTGTGTGGTGAATTTCCACGGCTACGAGCTGTGCCTGAGCGACTCTGACGATGAGCCTGCCGAGGGGGAACCACCGTATCGCTGTGAACTGTGCAATCAGTCGTACACGCGAAAACATCGCCTGATGCGTCACACCCTCGAGGAGCACGCGCAATCGCCCATTTCGCAGCGCTGCAACCTGTGCAAAGTTGGCTTTGTGTGTGCCAAGCTCTTTGAACAGCACCAGCGGACCCAGTGCCAGAGCAAAGTGAAGCGCTATCGCTGCCGCAAGTGCCCGGGGAAGTTCATGTGGCTGGAGAATCTGGAGCGGCATGCCTGCTCCCATCGCAGGGAGGAGCAGTCGTACAGGCAAATCATCTGCTGCCTGTGCGATGTGCAACTGTACAGCTTGAGGCAGCTGCGCGCTCACCTGGCCACCCATCGACATGGCTTGAGTGGCATTGATCCGGAGCACAAGTCCACCTTCTTCCGTTCCTACTATCCCAACGGATTGGGCTGCAGCCTCTCCGAGCTGAGCGCCCGCATAGCCGGGGACTATGAGGCCCAAGACTTCGGACGCTACTACAACGCCTGCACGGGAAGTGGTCAGGAGCTGGATCTCTTTGACTCCGACGCGGAGGAGAGCGATGCGCACGAAACGGAGGAAAAGCCGAAACTCCTGCACATCTGCCTGCTGTGTGGCGAGACTTCCATTCGCCTGCTCAAGCTGCTGCAACATCAGAGGAGAGTCCACTCTGCAGAGGACACCGCGTACCCCTGCTCTTGCCAGGACTGTGGCGCCGGCTTCGTGTCCGATGCCTTGCTGGAGCAACATCGTAGACGTTCCTGTGCCAAGAAGCACTCGAAATATCACTGCCAGCGCTGCAATCTTCATTTTGTGTGGCAATCGAACTACGAGCAGCATCTGCGTTTGTACCACCCCAAGGATGAGGATCAGGAGCAGTCGGAGGACTGCCAGCCAGGTCGCAAATATAAATCTTCGCCCGTCAAGCTACAGTGCGATGAATGTGAAAAGGTCTTCATTTGGCACAAGGATCTCACGCGACACAAGCGAATGCATCGCCCCCGTCGGCAGCCCAATATGAGTGTGCCCATTGCGATCGCAAagcagcagcagcagcaggagagtgCTGCAAATGAGGAGCAGCCCTCTGCCGCCCAGTCGACGTCTACGAACAGTATTCAGCGCATGCCCGCGGAGCAGCTGAGCCAACTATGCCGTCCAAATGGCTGCAAGCAAATCCAGTGCATGATTTGCCTGTCGCGCCACTCGAAGATCGCCGATCTGAGGACTCACCTAAGCGGGCACCAGTGTGGCGCGGGCTTTCCACAGGACAGGGACATTGCCAGTGCCTCGCGCTCGTTGTATCCCGAACTGGACACTACGCTGGATAAGCAGGAGCTGGTGCAGAGGATCATTAGCGATGTGGCCAGCGGCTTGGAGTTGGAGCGATTCGTTTCCATAACCAACGAGGCTGGCATCGAGCTCTCGCTGGAGAGCAGTGAAACGGAAACGGACTCCGagcaggaggatgaggagaGCTCCGAGGAGGCGGACCAGCAGCGATACGCCTGCAACATCTGCCAGCTGAAGGTGAAGCGGAAGCATCAATTGTATGCCCACCAGTTGGAGCAGCACCAGTGGGAGGAGGCGTCGCTCGTGTGCGCCCACTGTCAGGCGAGATTCGTGAGTGAGGCGCTGCTGGAGCATCACTACAGGACCCTCTGCCGGAATGCCCAGAAGCGCTTTCAGTGCCGCAAGTGCCCGCTACGCTTCCGCTGGCGGGAGAACCTAAAGCTGCACGCCAGCGCCTCCCATCAAAGGGAGCAAAGGGAACAGATCCAACCGGCTGCAACGGAGCCCAGCATTAAGGCTGAGTTCGAGCTGCAGTGCGGGGAGTGCAATCGCAGCTTCAAGATGCAGAAGGATCTCACGCGGCACACGCTGATGCATGCCCAGGAATCGAGCATTTATCGCTGTCGCTGGTGTGCCCGCCGCTTCTACAGGAAGGCCAATCTCCTGCAGCACATTGAGCGCCATGGCATCGGAGCTAGCCAGCTGCCCTACGCGGAAGCTCTCCTCAATGCCTATGGCCATCCCAACGGGCAGAAGAGCGTGGAATGCAAAGTGTGCAGCCTGAGCTTCACCAGCATCGCTGCCCTGCGCGTCCACCTGCAGACCATGGCGTCGGACAGTCACCACGAGCTGGCGTCCCACCAGAACTACTCGATAACCAACCAAATGGGATTCGAGCTGCACTTGGATGACTCGGAGACGGATGAGGAGGAGTCCAAGCCACCGGGCACGCCTGCCCTCTACACGTGTGGCATGTGCCAGCTGCGGTGTGCACGGAAGTACGAGctgcatcagcaccagcaggcCATGCACAGGCTGGAGAAGATACCCGATGGCTGCGATCGGTGCATTTTCAAGAGCGTCTCCCCCGATCTTATCGCGCACCACAAGCGGGTGCAGTGCCACAACCAGGAGAAGCAGTTCAACTGCGCCAAATGCGACTACAAGTTCATGTGGGAGTccaatctgctgctgcacatgcAACTGCAGCACGGAAAGGCCGAAGAACAGGAACACGATCCACCGCTGGATGAGCCCGCGGAGCAGAAGACTGTGTGCCAGATCTTCCAGTGCGGCCTCTGCCCCAGGAAGTACAATCGCAAGGATCGACTGACGGCGCATGTGAAGAAGTTCCACAACCCAGTGGCAGGAACACCAAGCGCCATTCGGGCTCCCATTCGGCCAACGTCGCCCAAGGAGCCGAAACGCTTTCTTTGCGCGTTCTGTGGCAAGGCTGTGAGCTCCTCCTCGAACCTGATCATCCACATGCGACGGCACACGGGCGAGAAGCCCTTTAAGTGCGACTACTGCGAAATGGCCTTCCCGCGCTCCTCCGATCTCCAGTGCCATCGACGAACGCACACCGGCGAGCGTCCACACATCTGCACCGTCTGCCAGAAGGGCTTTGCCAGATCCTacaaactgcagcagcacatgCGCATCCACAACGGCGAACGGCCCTACAAGTGCACCTACTGCGAGAAGAGCTTCACCCAGTCCAACGACCTGACGCTCCACATCCGCCGCCACACGGGCGAGCGTCCGTATCAGTGTGGGGTCTGTGGCGAGCGTTTTATCCAGGGCACGGCCCTGAAGAACCATCGACTGCAGCAAGGACACTACGACGAGGCCAGCCAGGGTGCTGCAGAGTCCTCAAGGCGCACGGTCCTAGAGCAATTTACAGTATAG
Protein Sequence: MLPSNICRTCALHSNNLLPLSTSLDKYTHKSFYDVLQELTQIDPLLENANDNLPQHLCTDCLDRLKDAYAFVEQARKVNGELLVRLQECLEESPIDIPQREIKAEIDIDEEQKYFTDSGEAQRVSDVDVESAGACSVEFKWTPESNSEDENAQSNEEDDDYVDEQQQQPYALRRSSRKVKPQADSEEEEVLVSPNKRRRGRPPGLAKSKSRNSEGRHACEVCNKTFSWFRDMKRHARAHYEKASFVCDICGKGFLRKDKYTFHLRSHEKREAKCQALQLKNEWRYAERLYSSGRLKRIQCKLCGLKCQRMQELRSHLVSHSRTDSLTTLRADSDVVKEHFVSVLPLDLEKIRQRVCTEIAEGQLEKYSCVVNFHGYELCLSDSDDEPAEGEPPYRCELCNQSYTRKHRLMRHTLEEHAQSPISQRCNLCKVGFVCAKLFEQHQRTQCQSKVKRYRCRKCPGKFMWLENLERHACSHRREEQSYRQIICCLCDVQLYSLRQLRAHLATHRHGLSGIDPEHKSTFFRSYYPNGLGCSLSELSARIAGDYEAQDFGRYYNACTGSGQELDLFDSDAEESDAHETEEKPKLLHICLLCGETSIRLLKLLQHQRRVHSAEDTAYPCSCQDCGAGFVSDALLEQHRRRSCAKKHSKYHCQRCNLHFVWQSNYEQHLRLYHPKDEDQEQSEDCQPGRKYKSSPVKLQCDECEKVFIWHKDLTRHKRMHRPRRQPNMSVPIAIAKQQQQQESAANEEQPSAAQSTSTNSIQRMPAEQLSQLCRPNGCKQIQCMICLSRHSKIADLRTHLSGHQCGAGFPQDRDIASASRSLYPELDTTLDKQELVQRIISDVASGLELERFVSITNEAGIELSLESSETETDSEQEDEESSEEADQQRYACNICQLKVKRKHQLYAHQLEQHQWEEASLVCAHCQARFVSEALLEHHYRTLCRNAQKRFQCRKCPLRFRWRENLKLHASASHQREQREQIQPAATEPSIKAEFELQCGECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRKANLLQHIERHGIGASQLPYAEALLNAYGHPNGQKSVECKVCSLSFTSIAALRVHLQTMASDSHHELASHQNYSITNQMGFELHLDDSETDEEESKPPGTPALYTCGMCQLRCARKYELHQHQQAMHRLEKIPDGCDRCIFKSVSPDLIAHHKRVQCHNQEKQFNCAKCDYKFMWESNLLLHMQLQHGKAEEQEHDPPLDEPAEQKTVCQIFQCGLCPRKYNRKDRLTAHVKKFHNPVAGTPSAIRAPIRPTSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDYCEMAFPRSSDLQCHRRTHTGERPHICTVCQKGFARSYKLQQHMRIHNGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRLQQGHYDEASQGAAESSRRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00580900;
90% Identity: -
80% Identity: -