Dper004606.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila persimilis
Gene Symbol
VEZF1
Assembly
GCA_003286085.2
Location
NW:21703587-21708683[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.002 0.11 12.6 1.1 1 23 216 238 216 238 0.96
2 26 0.032 1.8 8.9 1.7 1 23 244 266 244 266 0.97
3 26 0.031 1.8 8.9 1.6 2 23 298 319 297 319 0.96
4 26 0.0025 0.14 12.3 2.8 1 23 392 415 392 415 0.94
5 26 2.1 1.2e+02 3.2 1.1 2 22 423 443 422 443 0.94
6 26 0.44 25 5.3 1.4 1 23 452 474 452 474 0.97
7 26 1.6 90 3.5 0.3 3 23 486 506 484 506 0.95
8 26 0.0075 0.42 10.8 2.0 1 23 589 612 589 612 0.97
9 26 0.03 1.7 8.9 0.1 2 22 622 642 622 642 0.94
10 26 0.28 16 5.9 4.8 1 23 651 674 651 674 0.96
11 26 0.0011 0.063 13.4 1.6 2 23 700 721 699 721 0.97
12 26 1.3e-05 0.00071 19.6 2.8 1 23 729 751 729 751 0.99
13 26 0.0043 0.24 11.6 0.7 1 23 903 926 903 926 0.94
14 26 0.01 0.57 10.4 0.5 2 22 934 954 933 954 0.95
15 26 0.04 2.3 8.5 0.6 1 23 963 986 963 986 0.90
16 26 1.8e-05 0.001 19.1 1.2 2 23 1007 1028 1006 1028 0.97
17 26 0.00014 0.0079 16.3 1.2 1 23 1035 1057 1035 1057 0.98
18 26 0.029 1.6 9.0 0.0 2 21 1084 1103 1083 1104 0.93
19 26 0.012 0.67 10.2 3.9 1 23 1150 1173 1150 1173 0.96
20 26 0.0067 0.38 11.0 0.5 1 23 1210 1233 1210 1233 0.96
21 26 0.00029 0.016 15.3 1.5 1 23 1257 1280 1257 1280 0.97
22 26 5.4e-06 0.00031 20.7 0.2 2 23 1306 1327 1305 1327 0.95
23 26 0.00015 0.0085 16.2 2.9 1 23 1333 1355 1333 1355 0.99
24 26 3.6e-06 0.0002 21.3 2.0 1 23 1361 1383 1361 1383 0.97
25 26 5.5e-08 3.1e-06 27.0 2.4 1 23 1389 1411 1389 1411 0.99
26 26 0.0013 0.072 13.3 0.1 1 21 1417 1437 1417 1441 0.91

Sequence Information

Coding Sequence
ATGCTGCCTAGCAATATTTGCCGTACGTGTGCCCTGCAAAACAGCAATTTGCTGCCCCTCTCGACTTCCTTGGACAAGTACACGAATAAAAGTTTCTATGATGTGCTCCAAGAGCTGACACAGATCGACCCCCTGCTGGAGAATGCTGACGACAATCTGCCCCAACATCTGTGCGCAGATTGCTTGGACAGGCTGGAGAGCGCCTACGCCTTTGTGGAGCAGGCCAGAAAAGTCAATGGAGAGCTGCTAGTGCGGCTGCGGGAATGTCTGGAGGAGACCCCCATTGACATACCACAGCAGCAGATTAAAACAGAGATCGACATTGACGAGGAGCAAAGAGATTTTAGTGATTCTGGAGAGGCACAGAGGTCGTCCGACGTGGATGTGGAGTCGGCTGGCGTGTGCTCCGTCGAGCTGAAATGGACGCCAGAAAGTGCCAGCGAGGATGAGAATGCCGCCGATGCACTCTCAAACGATGAAGCTGATGATTTGGATGAGCAGCAGCCCTATATATTGCGGCGAAGTCCCCGTAAAGTCAAGCTACAGGCAGACAGTGAAGAGGAGGTCAGTACTTCAACCAACAAGCGGCGACGTGGACGTCCTCCTGGTCTGGCCAAAAGCCAGTCAAGGAATTCCGAAGGCCGTCATGCTTGTGAGGTGTGTGGCAAAACGTTTTCCTGGTTCCGGGACATGAAGCGTCACGCTCGCATTCATTACGAAAAGGCCTCGTTCGTCTGCGACACCTGTGGCAAGGGCTTTCTGCGCAAGGATAAGTACACGTTCCATCTGCGCTCCCACGAGAAGCGGGAGGCCAAGTGCCAGGCCCTCCAGCTGAAGAACGAGTGGAGATACGCGGAGCGTTTGTACAGCTCCGGGCGACTGAAGAGAATACAATGCAAATTGTGTGGCTTAAAGTGCCAGCGCATGCAGGAGCTCCGATCCCATTTAGCGAGTCACGTCCGCGGGGATAGTTTGTTTAGTCTGCGAGCGGACAACGATGTGGTCAAAGAACATTTTGCCAGTGTGCCATTTGACCTGGAAAAGATCAAGCAGCAAATTTGCTCGGAAATTGCCGACGGGCAGATGGAAAAGTACTCTTCTGTGGTCAATTTCCATGGCTACGAGCTGTGCCTGAGCGATTCTGACGATGAGCCTGCCGGTGGAGACCCACCGTACCATTGTGACCTGTGCAATCTGTCGTACACACGCAAATACCGCCTGATGCGGCACACCCTGGAGGAGCACACCCAATCGCCCATTCCCCTGCGCTGCAACCTCTGCAAAGTGGGTTTTGTGTGTGCAAAGCTCTTTGAACAGCACCAGCGGACCCAGTGCCAGAGCAAAGTGAAGCGCTATCGTTGCCGCAAGTGTCCGGGGAGGTTTATGTGGCTGGAGAACCTTGAGCGGCATGCCTGCTCCCATCGCAAGGAGGAGCAGTCATACAGGCAAATCATCTGTTGCTTGTGCGATGCCCAGCTTCCCAGCTTAAGGCGGCTGCGCGCTCACCTGGCCACCCATCGACATGGATTGAGTGGCATTGATCCGGAGCAGAATTCTGCCTTCTTCCGTTCTTACTATCCCAACGGATTGGACAGCAGCCTCTCCGAGCTGAGCACCCGCATAGCTGGGGACTATGAGACCCAGGACTTTGGACGCTACTACAATGCCTGCACGGGAAGTGGTCAAGAGCTGGATCTCTTTGACTCCGACACGGAGGAGAGCGATGCAGACGCAGACAAAACGGAGGAAAAGCCGAATCCCTCCCACACCTGCCTCCTATGTGGAGAGACTACCACTCGGCTGCTCAAGCTGCTGCAACATCAAAGGAGACTTCACTCCGAAGAGGGCACCACGTACCCCCGCTCTTGCCAGGATTGCGGCGCTGGCTTCGTCTCTGACCCTTTGCTTCAGCAACATCGCAGACGTTCCTGTGCCAAAAAGCACTCGAAATACCACTGCCAGCGATGCAATCTTCATTTTGTGTGGCAATCGAACTACGAGCAACACCTGCGATTGTACCACGACAAGGATGAGGATCAGGAGCAGTCCGAGGACTGCCAGCAGGGTAGAAAACATAAATCTTCGGCCGCCAAGCTTCAGTGCGATGAATGTGAAAAGGTCTTCATTTGGCACAAGGATCTTACTCGTCACAAGCGGATGCATCGCCCCCCGTCGGCAGCCCAATACGAGTGCGCCTTTTGCGACCGCAAGTTCCACCGCAAGGATGGCCTCAAGTCCCACATGCGGGTGCACAGCGAGCAGCATCAGGAGACTGTGAATGAGGAGCAGCCTTGCGTCCAATCGAACTCTACGAACAGTATTCAGAGAATGCCAGGGGAGCAGCTGGCCCAACTATGCCGTCCAAATGGCTGCAAGCAAATCCAGTGCATGATTTGCCTCTCACGCCACTCGAAGATCTCCGATCTGAGGAATCACCTAAGCGCGCACCAATATAGCGTGTGCTTTCCACAGGAGAGAGATATTCCCAGTGCCTCGCTTTTGTTGTATCCGGAGCTGGGCACTGCCCTGGATAAACAAGAGCTGGCGGATAGGATCATGAGCGATGTGGCCGGCGGCTTGGAGTTGGAGCGTTTTATTTCCATAACCAACGAGGCTGGCCTTGAGCTCTCGCTGGAGAGCAGTGAAACGGAAACGGATTCAGAGCAGGAGGATGACGAGAGCTCCGAAGAAGCTGACCAGCAGCGGTACGCCTGCAACATCTGCCAGGTGGAGGTGAGGCGAAAGCATCAATTGTATGCCCACCAGCTGGAGCAACACCAGTGGGAGGAGGCTTCGCTTGTGTGTGCCCACTGTCAGGCGAGGTTCGTGAGTGAGACGCTGCTGGAGCATCACTACAGAACCCTCTGCCGGAACCCGCAGAAGCGTTTCCAGTGCCGAAAGTGCCCGCTTCGGTTCCGCTGGCGGGAGAACCTGAAGCTGCACGCTAGTGCCTCGCATCAGCAAAGAGAACAGCCGCCAGCTGCAGAGGAACCCAGCATCCAGGCTGAGTTCGACCTCCAGTGCGGGGAGTGCAATCGCAGCTTCAAGATGCAGAAGGATCTCACGCGGCACACGCTGATGCATGCCCAGGAATCCAGCATATATCGCTGTCGTTGGTGCGCGCGCCGCTTCTACAGGAAGGCCAATCTCCTGCAGCACATTGAGCGGCACGGCATCGGAGCTAGCCAGCTGCCCTACGCGGAAGCCCTCCTCAGTGCCTATGGCCAAGCCAATGGTCAGAAGAGCGTGGAGTGCAAAGTGTGCAGCTTGAGCTTCCCCAGCATTGCTGCCCTTCGCGTCCATCTCGAGACCACGGCGTCGGGCAGTCACCACGAGCTCTCGTCCCTGCAGAACTACTCGATAACCAACCAAATGGGTTTCGAGCTCCACTTGGACGATTCAGAGACGGACGAGGAGGAGTCCAAGCCACCGGGCACGCCAGCTCTCTACACCTGTGGCATGTGCCAGCTCCGGTGTGTGCGGAAGTACGAGCTGCATCAGCACCAGCAGGCCATGCACAGGCTGGAGAAGATCCCCGACGGCTGCGATCAGTGCATTTTCAAGAGTGTCTCTCCCGATCTTATCGCGCATCACAAGCGAGTGCAGTGCCACAACCGGGAGAAGCAGTTCACCTGCGCCAAATGCGGCTACAAGTTCATGTGGGAGTCCAATCTcctgctgcacatgcagctGCAGCACGGGAAGACCGAAGAACAGGAAGATCCACCCCTGGATGAGCCCGcagagcagaaagctgtgtgTCCAATCTTTCAGTGCGGCCTCTGCCCGAGGAAATACAATCGCAAGGACCGGCTGACGGCCCATGTGAAGAAGTTCCACAACCCAGTGGGAGGGACTCCGAGCGCCGTACGGGCTCCCATCCGGCCAACGTCGCCCAAGGAGCCGAAACGCTTCCTTTGCGCCTTCTGTGGCAAGGCTGTGAGCTCCTCCTCCAACCTCATCATCCACATGCGTCGGCACACGGGCGAGAAGCCTTTCAAGTGCGACTACTGCGAAATGGCCTTTCCGCGCTCCTCCGATCTCCAGTGCCATCGCCGGACGCACACCGGAGAGCGGCCCCATATCTGCACCGTCTGCCAGAAGGGCTTCGCCAGATCCTACAAACTGCAGCAGCACATGCGCATCCACAATGGCGAGCGGCCCTACAAGTGCACCTACTGCGACAAGAGCTTCACCCAGTCAAACGACCTGACGCTCCACATTCGGCGCCACACGGGCGAGCGTCCCTATCAGTGCGGGGTCTGTGGCGAGCGTTTTATCCAGGGCACGGCCCTGAAGAATCATCGCCTGCAGCAGGGCCACTATGACGAGGCCAGCCAAGGAGCTGCAGAGTCCTCAAGGCGCACGGTCCTAGAGCAATTTACGGTATAG
Protein Sequence
MLPSNICRTCALQNSNLLPLSTSLDKYTNKSFYDVLQELTQIDPLLENADDNLPQHLCADCLDRLESAYAFVEQARKVNGELLVRLRECLEETPIDIPQQQIKTEIDIDEEQRDFSDSGEAQRSSDVDVESAGVCSVELKWTPESASEDENAADALSNDEADDLDEQQPYILRRSPRKVKLQADSEEEVSTSTNKRRRGRPPGLAKSQSRNSEGRHACEVCGKTFSWFRDMKRHARIHYEKASFVCDTCGKGFLRKDKYTFHLRSHEKREAKCQALQLKNEWRYAERLYSSGRLKRIQCKLCGLKCQRMQELRSHLASHVRGDSLFSLRADNDVVKEHFASVPFDLEKIKQQICSEIADGQMEKYSSVVNFHGYELCLSDSDDEPAGGDPPYHCDLCNLSYTRKYRLMRHTLEEHTQSPIPLRCNLCKVGFVCAKLFEQHQRTQCQSKVKRYRCRKCPGRFMWLENLERHACSHRKEEQSYRQIICCLCDAQLPSLRRLRAHLATHRHGLSGIDPEQNSAFFRSYYPNGLDSSLSELSTRIAGDYETQDFGRYYNACTGSGQELDLFDSDTEESDADADKTEEKPNPSHTCLLCGETTTRLLKLLQHQRRLHSEEGTTYPRSCQDCGAGFVSDPLLQQHRRRSCAKKHSKYHCQRCNLHFVWQSNYEQHLRLYHDKDEDQEQSEDCQQGRKHKSSAAKLQCDECEKVFIWHKDLTRHKRMHRPPSAAQYECAFCDRKFHRKDGLKSHMRVHSEQHQETVNEEQPCVQSNSTNSIQRMPGEQLAQLCRPNGCKQIQCMICLSRHSKISDLRNHLSAHQYSVCFPQERDIPSASLLLYPELGTALDKQELADRIMSDVAGGLELERFISITNEAGLELSLESSETETDSEQEDDESSEEADQQRYACNICQVEVRRKHQLYAHQLEQHQWEEASLVCAHCQARFVSETLLEHHYRTLCRNPQKRFQCRKCPLRFRWRENLKLHASASHQQREQPPAAEEPSIQAEFDLQCGECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRKANLLQHIERHGIGASQLPYAEALLSAYGQANGQKSVECKVCSLSFPSIAALRVHLETTASGSHHELSSLQNYSITNQMGFELHLDDSETDEEESKPPGTPALYTCGMCQLRCVRKYELHQHQQAMHRLEKIPDGCDQCIFKSVSPDLIAHHKRVQCHNREKQFTCAKCGYKFMWESNLLLHMQLQHGKTEEQEDPPLDEPAEQKAVCPIFQCGLCPRKYNRKDRLTAHVKKFHNPVGGTPSAVRAPIRPTSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDYCEMAFPRSSDLQCHRRTHTGERPHICTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRLQQGHYDEASQGAAESSRRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00580900;
90% Identity
iTF_00580900;
80% Identity
-