Daff015256.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila affinis
Gene Symbol
VEZF1
Assembly
GCA_037356375.1
Location
JAZHFB010000003.1:334612-339113[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 0.0019 0.16 12.8 1.1 1 23 215 237 215 237 0.96
2 21 0.032 2.6 9.0 1.7 1 23 243 265 243 265 0.97
3 21 0.05 4.2 8.3 2.4 2 23 297 318 296 318 0.97
4 21 0.0022 0.18 12.6 1.0 1 23 391 414 391 414 0.92
5 21 3.1 2.6e+02 2.7 1.3 2 22 422 442 421 442 0.95
6 21 0.53 44 5.1 1.5 1 23 451 473 451 473 0.97
7 21 0.33 27 5.8 0.5 3 23 485 505 484 505 0.97
8 21 0.0026 0.21 12.4 0.6 1 23 557 580 557 580 0.97
9 21 0.0038 0.32 11.9 0.2 2 22 590 610 587 610 0.90
10 21 0.0011 0.093 13.5 1.6 2 23 668 689 667 689 0.97
11 21 8.9e-06 0.00074 20.2 2.5 1 23 697 719 697 719 0.99
12 21 0.0043 0.36 11.7 1.9 1 23 834 856 834 857 0.95
13 21 0.04 3.3 8.6 0.6 1 23 876 899 876 899 0.90
14 21 1.8e-05 0.0015 19.2 1.2 2 23 922 943 921 943 0.97
15 21 0.00014 0.012 16.4 1.2 1 23 950 972 950 972 0.98
16 21 0.029 2.4 9.1 0.0 2 21 999 1018 998 1019 0.93
17 21 0.012 0.99 10.3 3.9 1 23 1065 1088 1065 1088 0.96
18 21 0.0067 0.56 11.1 0.5 1 23 1125 1148 1125 1148 0.96
19 21 0.00029 0.024 15.4 1.5 1 23 1172 1195 1172 1195 0.97
20 21 5.5e-06 0.00045 20.8 0.2 2 23 1223 1244 1222 1244 0.95
21 21 0.0013 0.11 13.4 0.1 1 21 1318 1338 1318 1342 0.91

Sequence Information

Coding Sequence
ATGCTGCCCAGCAATATTTGCCGGACGTGTGCCCTGCAGAATAGTAATTTGCTGCCCCTGTCCACGTCCTTGGACAAGTACACAAACAAAAGTTTCTATGATGTGCTCCAAGAACTGACACAGATCGATGTAACCTCTGCTGAGAATGCGGACGACAATCTGCCCCAGCATCTGTGTACAGATTGCCTGGACAGGCTGGAGAATGCCTACGCCTTTGTAGAGCAGGCAAGAAAGGTCAATGGAGAGCTGCTGGTGCGGCTGAGGGAATGTCTGGAGGAGAGCCCCATTGACATACCACAGCAGCAGATCAAAACGGAGATCGACATTGATGAGGAGCAAAGAGATTTCACAGATTCAGGCGAGGCACAAAGATCGTctgatgtggatgtggagtCGGCTGGCGTGTGCTCCGTTGAGCTGAAATGGACTCCAGAAAGCGCCAGCGAGGAGGAGAATGCCGCCGATGCACTCTCAAACGATGAAGATGATGATGCGCAGCCCTATATCTTGCGGCGAAGTCCCCGCAAAGTCAAGCAACAGGCAGACAGCGAAGAGGAGCAAGTCAGTCCTTCACCCAACAAGCGGCGTCGCGGGCGTCCTCCTGGTCTGGCCAAAAGCCAGTCAAGGAATTCCGAAGGCCGTCATGCTTGTGAGGTGTGTGGCAAAACGTTTTCCTGGTTCCGGGACATGAAACGACATGCTCGCGTCCATTACGAGAAGGCCTCATTCGTCTGCGATACTTGTGGCAAGGGATTCCTGCGCAAGGACAAGTACACCTTCCATCTGCGCTCCCACGAGAAGCGGGAGGCCAAGTACCAGGCCCTCCAGCTGAAGAACGAGTGGAGGTTCGCCGAGCGTTTGTACAGCTCTGGACGACTGAAGAGAATGCAGTGCAAATTGTGCGGCTTGAAGTGCCAGCGAATGCAGGAGCTTCGATCCCATTTAGAGAGCCACGTCCACACGGACAGTTTGTTCAGTCTGCGAGCGGACAACGATGTGGTCAAAGAACATTTTGCCATTGGCCCATTTGACCTGGAAAAGATCAAGCAGCAAATTCGCTCGGAAATAGCCGAAGGGCAGCTGGAAAAGTACTCTTCAGTGGTCAATTTCCATGGCTACGAGCTGTGCCTGAGCGATTCTGACGATGAGCCTGCCGGTGGAGAGCCACCGTACCTTTGTGACCTCTGCAATCTGTCGTACACTCGCAAATATCGACTGATGCGGCACACCCTGGAGGAGCACACCCAATCGCCCATTTCCCAGCGCTGCAACCTCTGCAAAGTGGGTTTTGTGTGTGCAAAGCTCTTCGAACAGCATCAGCGAACCCAGTGCCAAAGCAAAGGGAAGCGCTATCGTTGCCGTAAGTGTCCAGGGAAGTTCATGTGGCTGGAGAATCTGGAGCGGCATGCCTGCTCACATCGCAAGGAGGAGCAGTCGTACAGGCAAATACTCTGTTGCCTGTGCGATGCCCAGCTTCCCAGCTTAAGGCAGCTGCGCGCTCACCTGGCTACCCATCGACATGGATTGAGCGCTGGGGACTATGAGGCCCAAGACTTTGGACGCTACTACAACGCCTGCACGGGAAGTGGTCAAGAGTTGGATCTCTTTGATTCTGATACAGAGGAGACggatgaggcagacaaaacagAGGAAAAGCCAAAACCCTCGCACACCTGCCTGCTCTGTGGAGAGACTACTATTCGCCTGCTCAATCTGCTGCAACATCAAAGGATACTCCACTCCGACGAGGGCACCACGTACCCCTGCTCTTGCCAGGATTGTGGCGCTGGCTTTGTCTCAGAGCCCTTGCTACAGCAACATCGAAGACGTTCCTGTGCCAAAAAGCACTCAAAATACCACTGCCAGCGATGCAATCTTCATTTTGTGTGGCAATCGAACCACGAGCAACATCTGCGCTTGTACCACGACAAGGATGGGGATCAGGAGCAGTCGGAGGACTGCCAGCAGGGTGGAAAACATAAATCTTCGGCCGCCAAGCTTCAGTGCGATGAATGTGAAAAGGTCTTCATTTGGCACAAGGATCTCACCCGTCACAAGCGAATGCATCGCCCACCGTCGGCAGCCCAATACGAGTGTGCCTATTGCGACCGGAAGTTTCACCGCAAAGATGGCCTCAAGTCCCACCTGCGGGTGCacaacgagcagcagcaggagacaGTGAATGAGGAGCCGTCTTGCGCCCAATCGACATCTACGAACAGTATTCAGAAAATAGCCGGGGAGCAGCTGACCCAACTATGCCGAGAGAGATATTCCCAGTGCCTCGCGCTCGTTGTATCCGGAACTGGGCACTGCCTGGATaagcaggagctggagaagAGGATCATGAGCGATGTGGCCAGCGGCTTGGAGTTGGAGCGATTCATTTCCATAACCAACGAGGCTGGCATTGAGCTCTCTCTTGAGAGCAGTGAAACGGAAACGGATTCAGAACAGGACGAGGATGACGAGAGCTCCGAGGAAGCTGACCAGCAGCGGTACGCCTGCAACATCTGCCAGGTGGAGGTGAGGCGAAAGCATCAATTGTATGCCCACCAGTTGGAGCATCACCAGTGGGAGGAGGCTTCGCTTGTGTGTGCCCACTGTCAGGCGAGATTCAAGCGTTTCCAGTGCCGAAAGTGTCCGCTACGCTTCCGCTGGCGGGAGAACCTGAAGCTGCACGCAAGTGCCTCCCATCAGCAAATAGGGCAGCCCCAAGCTGCAGAGGAACAGAGGAACGGCATCCAGACTGAGTTCGACCTCCAGTGTGGGGAGTGCAATCGCAGCTTCAAGATGCAGAAGGATCTCACGCGGCATACGTTGATGCATGCCCAGGAATCGAGCATATATCGTTGTCGTTGGTGTGCCCGCCGCTTCTACAGGAAGGCCAATCTCCTGCAGCACATTGAGCGGCATGGCATCGGAGCTAGCCAGCTGCCCTACGCGGAAGCTCTCCTCAATGCCTATGGTCAACCCAATGGCCAGAAGAGCGTGGAGTGCAAGGTGTGCAGCTTGAGCTTCCCCAGTATTGCTGCACTTCGCGTCCATCTGGAGACCATGGCGTCGGGAAGTCACCACGAACTATCGTCCCTGCAGAACTACTCGATAACCAACCAAATGGGATTCGAGCTGCACTTGGATGACTCGGAGACGGATGAGGAGGAGTCCAAGCCACCAGGCACGCCTGCTGTCTACACCTGCGGCATGTGCCAGCTCCGGTGTGTGCGAAAGTACGAGCtgcatcagcaccagcaggcCATGCACAGGCTGGAGAAGATCCCCAATGGCTGCGATCTGTGCATTTTCAAGAGTGTCTCTCCCGATCTTATCGCGCATCACAAGCGAGTGCAGTGCCACAACCGCGAGAAGCAGTTCACTTGCGCCAAATGCGGCTACAAGTTTATGTGGGAGTCCAATCTCTTGCTGCACATGCAGCTGCAACATGGCAAGACCGAAGAACAGGATGATCCACCCCTGGATGAGCCCGTGGAGCAGAAGGCTCTGTGTCCAGTCTTCCAGTGCGGCCTCTGCCCAAGGAAATACAATCGCAAGGATCGGCTGACGGCCCATGTGAAGAAGTTCCACAACCCAGTGGTAGGGAGCGCTCCGAGCACCATACGGGCTGCTCCAATCCGACCAACCTCGCCCAAGGAGCCGAAACGCTTCCTTTGCGCCTTCTGTGGCAAGGCTGTGAGCTCCTCCTCCAACCTCATCATCCACATGCGTCGGCACACGGGCGAGAAGCCTTTCAATGCCATCGACGAACGCACACGGGGAACGGCCCCACATCTGCACCGTCTGCCAGAAGGGCTTCGCCAGATCCTACAAACTGCAGCAGCACATGCGCATCCACAACGGCGAGCGGCCCTACAAGTGCACCTACTGCGAAAAGAGCTTCACCCAGTCCAACGACCTGACACTCCACATCCGCCGCCACACGGCGAGCGTCCCTATCAGTGCGGGGTCTGTGGCGAGCGTTTCATCCAGGGTACGGCCCTGAAGAATCATCGCCTACAGCAGGGCCACTATGACGAGGCCAGCCAAGGAGCGGCAGAGTCCTCAAGGCGCACGGTCCTAGAGCAATTTACAGTTTAG
Protein Sequence
MLPSNICRTCALQNSNLLPLSTSLDKYTNKSFYDVLQELTQIDVTSAENADDNLPQHLCTDCLDRLENAYAFVEQARKVNGELLVRLRECLEESPIDIPQQQIKTEIDIDEEQRDFTDSGEAQRSSDVDVESAGVCSVELKWTPESASEEENAADALSNDEDDDAQPYILRRSPRKVKQQADSEEEQVSPSPNKRRRGRPPGLAKSQSRNSEGRHACEVCGKTFSWFRDMKRHARVHYEKASFVCDTCGKGFLRKDKYTFHLRSHEKREAKYQALQLKNEWRFAERLYSSGRLKRMQCKLCGLKCQRMQELRSHLESHVHTDSLFSLRADNDVVKEHFAIGPFDLEKIKQQIRSEIAEGQLEKYSSVVNFHGYELCLSDSDDEPAGGEPPYLCDLCNLSYTRKYRLMRHTLEEHTQSPISQRCNLCKVGFVCAKLFEQHQRTQCQSKGKRYRCRKCPGKFMWLENLERHACSHRKEEQSYRQILCCLCDAQLPSLRQLRAHLATHRHGLSAGDYEAQDFGRYYNACTGSGQELDLFDSDTEETDEADKTEEKPKPSHTCLLCGETTIRLLNLLQHQRILHSDEGTTYPCSCQDCGAGFVSEPLLQQHRRRSCAKKHSKYHCQRCNLHFVWQSNHEQHLRLYHDKDGDQEQSEDCQQGGKHKSSAAKLQCDECEKVFIWHKDLTRHKRMHRPPSAAQYECAYCDRKFHRKDGLKSHLRVHNEQQQETVNEEPSCAQSTSTNSIQKIAGEQLTQLCRERYSQCLALVVSGTGHCLDKQELEKRIMSDVASGLELERFISITNEAGIELSLESSETETDSEQDEDDESSEEADQQRYACNICQVEVRRKHQLYAHQLEHHQWEEASLVCAHCQARFKRFQCRKCPLRFRWRENLKLHASASHQQIGQPQAAEEQRNGIQTEFDLQCGECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRKANLLQHIERHGIGASQLPYAEALLNAYGQPNGQKSVECKVCSLSFPSIAALRVHLETMASGSHHELSSLQNYSITNQMGFELHLDDSETDEEESKPPGTPAVYTCGMCQLRCVRKYELHQHQQAMHRLEKIPNGCDLCIFKSVSPDLIAHHKRVQCHNREKQFTCAKCGYKFMWESNLLLHMQLQHGKTEEQDDPPLDEPVEQKALCPVFQCGLCPRKYNRKDRLTAHVKKFHNPVVGSAPSTIRAAPIRPTSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFNAIDERTRGTAPHLHRLPEGLRQILQTAAAHAHPQRRAALQVHLLRKELHPVQRPDTPHPPPHGERPYQCGVCGERFIQGTALKNHRLQQGHYDEASQGAAESSRRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00580900;
90% Identity
-
80% Identity
-