Dgri010571.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila grimshawi
Gene Symbol
L
Assembly
GCA_018153295.1
Location
JAECXY010001366.1:2253734-2290184[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 1.1e-05 0.00069 19.7 2.9 1 23 371 393 371 393 0.98
2 17 0.37 24 5.4 6.2 1 23 399 421 399 421 0.97
3 17 1.8e-07 1.2e-05 25.3 3.2 1 23 427 449 427 449 0.99
4 17 1.3e-05 0.00085 19.4 0.4 1 23 455 477 455 477 0.99
5 17 0.13 8.2 6.9 0.1 2 23 551 576 550 576 0.92
6 17 0.00044 0.028 14.6 0.4 2 23 609 631 608 631 0.96
7 17 0.029 1.9 8.9 0.7 1 23 696 718 696 718 0.97
8 17 0.0054 0.35 11.2 0.1 2 23 726 747 725 747 0.91
9 17 0.00022 0.014 15.5 0.1 1 23 755 779 755 779 0.93
10 17 5.4 3.5e+02 1.7 1.6 2 23 815 837 814 837 0.95
11 17 0.0027 0.17 12.1 1.1 1 23 887 910 887 910 0.97
12 17 0.0068 0.44 10.9 1.6 2 23 1084 1106 1083 1106 0.96
13 17 0.12 7.8 6.9 0.1 1 23 1112 1134 1112 1134 0.92
14 17 0.58 38 4.8 0.4 2 23 1142 1163 1141 1163 0.93
15 17 0.68 44 4.6 0.6 2 23 1262 1283 1262 1283 0.94
16 17 0.051 3.3 8.1 0.0 1 23 1293 1315 1293 1315 0.94
17 17 0.00023 0.015 15.5 1.2 1 23 1320 1342 1320 1342 0.97

Sequence Information

Coding Sequence
ATGTATATTGGCTATGTGGTTGGCGAAAAGGAGGAGGAGAATGGAGGCGCCACCAAGACGCCCAAGGCAGCCGATTTGCTCGAGCCCAAAGAGGAGTTGCTGAGCGCCGACGAAGGGGGCGAGGAGGAGTACGAGGAGGAGGACGATGATGAGCCCGACGAGGAGGAGGAGGAGCAGGACGACGAAGAGGAGGGCGATGGCGAGGGGCACCAGCAGCCCAGTGGCAATGAGAATGGGACTGAAAAGGAACAGCAGCAGCAGCGAGTCCAGTCCAATGAATCACACAGCAGTAGCCACGGGCAACGCCAATGGGCACTGCAAGTCGAGGTCCACATCCACTGTGAGCCGGCGGCGACGGCCGCTTCAGCCGCCTCCCTGGGGACGCTGCGCTGGCGCAGTGTGGATGGATGGATGGACTCTAGGAGTCCGCGCCCCGGTTCATATTGCAGTGTCCAAGTCAAGTTTTTGTTGCTGTTGTTACTGGGTTTGGGCTTTGGTTCGGGATCTGGACCTGGCAACATAAATGCTCCTCAAGACAAGGACATGGAGAATGTTGTTGAGCCAACTGACGACGACGACGAGCTGGACGAGGAGGATGAGGAGCTGGAGGATGACCTGGCGGATGATTTGCTTAGCCTCAGCGGCGATGAGGACTACGATGATGAGGAGCTGCAAAGTCTCGACAGTTTCTATTCCGACATGTACAGCACGCACACCTCGTCGAGCTACTCGCCCAGCATCTCGGATGGCACATTGACGCCCAACTCGGTGCAGCAGCAGCAGCTGCCCAAGGCTGCCGCCGAGGACAATCATTCCGAAGAGTCCAAGGCAAATGGTGAGGGTCCTGCTGCGGAGCAACAGGATCTGGCCAAGCCGAAGCGACCCGCTCATTTGCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAGCGCTGAAAATTGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAGTTGGCAACCGCAGGAGCAGCACACGGAACAGGAGCAGCAGCAGGAGCAGCAGGTGGCGGAGGTGGAGGAGTTGCCGCCAGCAAGTTTGATAAGTTGACAGGCGAAAGCATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCACGTCCAGAGCCATGCCGAACATTTGCCTTTCAAGTGCGAATACTGCGCCAAGCTGTTCAAGCACAAGCGATCCCGAGATCGCCACAAGAAGCTGCACACCAACGAGAGGAACTACAAGTGTCCGCACTGCGAGGCTGCTTTCTCCAGAAGCGATCATTTAAAGATTCACATGAAGACGCACGATATTCAGAAGCCATTCCAGTGCAGCATGTGCAATCGTGGCTATAATACTGCCGCTGCTTTGACCTCCCACATGCAGAAGCACAAGAAGAATGCGGCAATTCTGGCAGCTGGTGGCAATCCCAATGCTCTGAATTATAGTCCACGCTCGACGGGATCGGCGTCCATTTCGAGCAATGGCAGTTTGCACAAGCGACGCTATGCTTTGGCACTTGCCTCCGACAGCAGTCCAAGTCGCCTGGAGTTCCCCAAGCGGGCACGTGGTGTTACCGTGCCGACCACGCCCACTCCAACGCCCCTGCTGCGTTGCAGTTACTGCAGTCCCAAGGTGACCGAGTTTAGCAGCCTGGAACAGTTGAATGCCCATCTGCAGGCGGCACACGAACAGCAACAGCAGCCGGGCGCAAGGAGCTCGACAGCCACCAGCAGGGAGACCACAGTGGAGACAGTGGAGCCACCCACGAATGGTTTCCAGCTCAGCTGCGAATATTGCACAATGAAATTCGGAAATATTGCGGCACTCTTCCAGCACATGCGCACCACTCACTTGGATCGCCTAAGCAGTCCCAACTCGTATTATGAGCACTTTAATCGTTTGGCCACCGCGGGCACATTTAGTCCACGCTTGGATATGCCCAAGATCAAGCAGGATTTGCCGAGTCCGCCGGCGGAGGAGCTGCCAACGGATCTGAGCAGCAATAAGCGACGAGCGATGACGCCGCCAGCGCCACCTGGCGTCTTCTTTTGCAATCAGTGCAACGCAGGGTTGCCAGACTTTGAGAGTTTTCGCAATCATCTGAAGACGCACATTGCGGAAGGCATGCAACTGATATGTCCCCACTGCGGACTGAGTCTGCCGGAGCAGAGCGAATTCGAGCGACATGTTGTCGCCCATTTCCTGATCAGCAGCTCCGAGTTCAATTGCGGCGCCAGTTGTGGCAAATCTTTTGCCAAATCGGAGGAACTGCAACAGCATCTGATCAGCGAACATGTCCAGACGCTGCTCAAGTGTGTGATCTGCTCGGAGCTGTGCGAGAATCGCATGTCCATGCAGCTTCATTTGGCCTGTGCCCACAGTCAGGAGACGAAGCTGCTGCGGTGCAGCGCTTGCTTGGAACTCTTTCGCAACGATACGGATTTCCATGTGCATGTCAAGACGCGACATCAACTGGTGGGTGGCGGTGCTGCTGGCGGAGCAGTTGGTGGACCACCCACTGCTCCACCTGCCAATCCGTTGCAGTGCATGTTTTGCCGCGCTGTTTGCGCCTCGGAGCTGGAAATGCACTTCCATTTGGCGGCGCATGCTCGCCAATTCCGTTGTCCCAGTTGCCCGGAAACGTTCCACGTCGAATTCCTGCTCGATCGGCATATGCAGAGCCAGCATGGCGGCGTCAAGGATGGCAAACAGGAGCAGCAGGGTGCCAACAATGCGATGGGCAGTCTGTATGTGAATGCCTTGTTGCCACCGTTGGCGGCGGCAGCAGCGGCTGCGGCAGCTGCCACAAACAATAACAGTAATCTGCATATTGATTACAATGTGGCGTTCAAGGGTCTGTTTGGAGGCGGCAATGCCACGCCCACCAACACGCAGCCAACCAACAAGTTCTACAGTCCTTTGCAGGTGGATACAAGTGCGCTGAAGCCCCAACAGACGCCGCATCCCGCTCTGATGTACGGTCTCAGTCAGCGCTATTTGATGGAGATGTATGCGGCGAAGGCAACCTCGCCGGCGGCCAGTGCACCCGAGCTGCCGGCACAGGCAACCCAAGCGGCAAATGCGACGGCATCCAGCACGGGCAGCAGCTACAGTTGTGGCATGTGCGAGCGCCAGGATTTGCGCAGCGAGGCCGAACTGCATTCGCATCGCAAGTTGGCACACAATCTGAAGACGGGCGTCAGTTTGAGATGTGCCTACTGCTCAGGTAACTACAAGTCGCGGGCGGAGCTGGAGCAGCACATGAAGAGCTGCCACAATTCGAGTGGCAAGCACAAGTGTCTCATATGCGACGAGATCTTTCCGTCGCCGGCGATACTCGCCGAGCACAAGTTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGTGCCCATTGTGGCCAGCAGCTGGAGCATGTCGCCGCATTCCGTGCCCATCTCGGCGAGCATGGCAACGATGGTAATTTGCCCATGGCCTGCATTTGTTGCCGTCAAACTTTGCACTCGGAATTCGAGTTGAGTTTGCATGCCAAATTCCACACAAAATCACCGAGTTGTGGCAGCCTCCAGGAGCCCGTCTGTGCACTGTGCCTGGAACCCTTGCCGGGTGCGGGCGAAACCGCCAAGCTGTGCGAGAAATGTTGTCGCAAACATAACCTGAATGGCAAACGCAACAAGGACGCAGCTTTGCCACCAGCAGCTCCAGTCCCACCAGCAGCCAGCACAGTGGGCTATCTCGAGAATCGTTGTAATCTGTGCAAACTGATATTGCCACATGCCAAGAAACTGCAGGAGCATCTCGTGGAGCACACGTTTGCCGGCACCGAGCAGCGTGGTTTCAATTGCTACATTTGCTCGGCGGTCTTTACGGCACCCGGTGGCCTTTTGGCCCACATTGGGGAGCATGGTGCTCGACCCTACGATTGTAATTTGTGCCCGGAGAAGTTTTACTTTCGTGCCGAGCTCGAGCATCATCAGCGTGCCCACGAACTAAGGCAAATCCCAACAGCCGCTGCTGCACCGACACGGCCCACAACCAAGCAGGAGGCGCAGCACAGCTCATCGGCCAGTTCACCCGTGCTCACGCTCAGTCCCAGTCATGTGAAGCAGGAGCTCTACGAATCGGAGGCGGCTAACTCACCGCAGCCCGACGAGGAGTCACCCACGCAGGAGGAGGAGGAGTACATTGAGGTCGAGCAGATGCCACACGAGACCCGCTCCAACGAACTGGTCTCCACGGAACGCTCCAGCAACAGCGCCTGA
Protein Sequence
MYIGYVVGEKEEENGGATKTPKAADLLEPKEELLSADEGGEEEYEEEDDDEPDEEEEEQDDEEEGDGEGHQQPSGNENGTEKEQQQQRVQSNESHSSSHGQRQWALQVEVHIHCEPAATAASAASLGTLRWRSVDGWMDSRSPRPGSYCSVQVKFLLLLLLGLGFGSGSGPGNINAPQDKDMENVVEPTDDDDELDEEDEELEDDLADDLLSLSGDEDYDDEELQSLDSFYSDMYSTHTSSSYSPSISDGTLTPNSVQQQQLPKAAAEDNHSEESKANGEGPAAEQQDLAKPKRPAHLXXXXXXXXXXXXALKIANKLRKINKEAKLATAGAAHGTGAAAGAAGGGGGGVAASKFDKLTGESIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGVTVPTTPTPTPLLRCSYCSPKVTEFSSLEQLNAHLQAAHEQQQQPGARSSTATSRETTVETVEPPTNGFQLSCEYCTMKFGNIAALFQHMRTTHLDRLSSPNSYYEHFNRLATAGTFSPRLDMPKIKQDLPSPPAEELPTDLSSNKRRAMTPPAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLISSSEFNCGASCGKSFAKSEELQQHLISEHVQTLLKCVICSELCENRMSMQLHLACAHSQETKLLRCSACLELFRNDTDFHVHVKTRHQLVGGGAAGGAVGGPPTAPPANPLQCMFCRAVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDGKQEQQGANNAMGSLYVNALLPPLAAAAAAAAAATNNNSNLHIDYNVAFKGLFGGGNATPTNTQPTNKFYSPLQVDTSALKPQQTPHPALMYGLSQRYLMEMYAAKATSPAASAPELPAQATQAANATASSTGSSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRNKDAALPPAAPVPPAASTVGYLENRCNLCKLILPHAKKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLAHIGEHGARPYDCNLCPEKFYFRAELEHHQRAHELRQIPTAAAAPTRPTTKQEAQHSSSASSPVLTLSPSHVKQELYESEAANSPQPDEESPTQEEEEYIEVEQMPHETRSNELVSTERSSNSA