Basic Information

Insect: Drosophila hawaiiensis
Gene Symbol: L
Assembly: GCA_037043685.1
Location: JBAMBA010000148.1:74292-84116[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1e-05 0.00068 19.9 2.9 1 23 166 188 166 188 0.98

2 17 0.35 23 5.6 6.2 1 23 194 216 194 216 0.97

3 17 1.7e-07 1.1e-05 25.5 3.2 1 23 222 244 222 244 0.99

4 17 1.3e-05 0.00083 19.6 0.4 1 23 250 272 250 272 0.99

5 17 0.12 8 7.1 0.1 2 23 346 371 345 371 0.92

6 17 0.00042 0.028 14.8 0.4 2 23 404 426 403 426 0.96

7 17 0.028 1.8 9.1 0.7 1 23 491 513 491 513 0.97

8 17 0.0052 0.34 11.4 0.1 2 23 521 542 520 542 0.91

9 17 0.00021 0.014 15.8 0.1 1 23 550 574 550 574 0.93

10 17 5.2 3.4e+02 2.0 1.6 2 23 610 632 609 632 0.95

11 17 0.0026 0.17 12.4 1.1 1 23 682 705 682 705 0.97

12 17 0.0065 0.43 11.1 1.6 2 23 879 901 878 901 0.96

13 17 0.12 7.6 7.1 0.1 1 23 907 929 907 929 0.92

14 17 0.55 37 5.0 0.4 2 23 937 958 936 958 0.93

15 17 0.65 43 4.8 0.6 2 23 1057 1078 1057 1078 0.94

16 17 0.048 3.2 8.3 0.0 1 23 1088 1110 1088 1110 0.94

17 17 0.00022 0.015 15.7 1.2 1 23 1115 1137 1115 1137 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1e-05	0.00068	19.9	2.9	1	23	166	188	166	188	0.98
2	17	0.35	23	5.6	6.2	1	23	194	216	194	216	0.97
3	17	1.7e-07	1.1e-05	25.5	3.2	1	23	222	244	222	244	0.99
4	17	1.3e-05	0.00083	19.6	0.4	1	23	250	272	250	272	0.99
5	17	0.12	8	7.1	0.1	2	23	346	371	345	371	0.92
6	17	0.00042	0.028	14.8	0.4	2	23	404	426	403	426	0.96
7	17	0.028	1.8	9.1	0.7	1	23	491	513	491	513	0.97
8	17	0.0052	0.34	11.4	0.1	2	23	521	542	520	542	0.91
9	17	0.00021	0.014	15.8	0.1	1	23	550	574	550	574	0.93
10	17	5.2	3.4e+02	2.0	1.6	2	23	610	632	609	632	0.95
11	17	0.0026	0.17	12.4	1.1	1	23	682	705	682	705	0.97
12	17	0.0065	0.43	11.1	1.6	2	23	879	901	878	901	0.96
13	17	0.12	7.6	7.1	0.1	1	23	907	929	907	929	0.92
14	17	0.55	37	5.0	0.4	2	23	937	958	936	958	0.93
15	17	0.65	43	4.8	0.6	2	23	1057	1078	1057	1078	0.94
16	17	0.048	3.2	8.3	0.0	1	23	1088	1110	1088	1110	0.94
17	17	0.00022	0.015	15.7	1.2	1	23	1115	1137	1115	1137	0.97

Sequence Information

Coding Sequence: ATGATGGCCTTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGGAGAATTTGATTGAAAAGATTCAGGCCACAAAGGAGATTACAAATAACGACATGTACAGCACGCACACCTCGTCGAGCTACTCGCCCAGCATCTCGGATGGCACATTGACGCCCAACtcggtgcagcagcagcagctgcccaagGCTGCCGCCGAGGACAATCATTCCGAAGAGTCCAAGGCAAACGGTGAGGGTCCTGCTGCGGAGCAACAGGATCTGGCCAAGCCGAAGCGACCCGCTCATTtgcatcatcaccatcatcaccattatcatcatcagcaggcGCTGAAAATTGCCAACAAGCTGCGCAAAATCAATAAGGAGGCCAAGTTGGCAACCGCAGGAGCAGCACAcggaacaggagcagcaggtgGCGGAGGTGGAGGAGTTGCCGCCAGCAAGTTTGATAAGTTGACAGGCGAAAGCATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCACGTCCAGaGTCATGCCGAACATTTGCCTTTCAAGTGCGAATACTGCGCCAAGCTGTTCAAGCACAAGCGATCCCGAGATCGCCACAAGAAGCTGCACACCAACGAGAGGAACTACAAGTGTCCGCACTGCGAGGCTGCTTTCTCCAGAAGCGATCATTTAAAGATTCACATGAAGACGCACGACATTCAGAAGCCGTTCCAGTGCAGCATGTGCAATCGTGGCTATAATACTGCGGCCGCTTTGACCTCCCACATGCAGAAGCACAAGAAGAATGCGGCAATTCTGGCAGCTGGTGGCAATCCCAATGCTTTGAATTATAGTCCACGCTCGACGGGATCGGCGTCCATTTCGAGCAATGGCAGTTTGCACAAGCGACGCTATGCTTTGGCACTCGCCTCCGACAGCAGTCCGAGTCGTCTGGAGTTTCCCAAGCGGGCACGTGGTGTTACCGTGCCGACCACGCCCACCCCAACGCCCCTGCTGCGTTGCAGTTACTGCAGTCCCAAGGTGACCGAGTTTAGCAGCCTGGAACAGTTGAACGCCCATCTGCAGGCGGCAcacgaacagcaacagcagccgggCGCAAGGAGTTCGACAGCCACCAGCAGGGAGACCACAGTGGAGACAGTGGAGCCAGCCACGAATGGTTTCCAGCTCAGCTGCGAGTATTGCACAATGAAATTCGGAAATATTGCGGCACTCTTCCAGCACATGCGCACCACTCACTTGGATCGCCTGAGCAGTCCCAATTCGTATTATGAGCACTTTAATCGTTTGGCCACCGCGGGCACATTTAGTCCACGCTTGGATATGGCCAAGATCAAGCAGGATTTGCCGAGTCCGCCGGCGGAGGAGCTGCCAACGGATCTGAGCAGCAATAAGCGAAGAGCTTTGACGCCGCCAGCGCCACCTGGTGTCTTCTTTTGCAATCAGTGCAACGCAGGGTTGCCAGACTTTGAGAGTTTTCGCAATCATCTCAAGACGCACATTGCGGAAGGCATGCAACTGATATGTCCCCACTGCGGACTGAGCCTGCCGGAGCAGAGCGAATTCGAGCGACATGTTGTCGCCCATTTCCTGATCAGCAGCTCCGAGTTCAATTGCGGCGCCAGTTGTGGCAAATCGTTCGCCAAATCGGAGGaactgcaacagcatctgATCAGCGAACATGTCCAGACGCTGCTCAAGTGTGTGATCTGCTCGGAGCTGTGCGAGAATCGCATGTCCATGCAGCTCCATTTGGCCTGTGCCCACAGTCAGGAGACGAAGCTGCTCCGGTGCAGCGCCTGCTTGGAACTCTTTCGCAACGATACGGATTTCCATGTGCATGTCAAGACGCGACATCAACTGGTGGGCGGAGGTGCTGCTGGCGGAGCAGTTGGAGGACCACCCACTGCTCCACCCGCCAATCCGTTGCAGTGCATGTTTTGTCGCGCTGTTTGCGCCTCGGAGCTGGAAATGCACTTCCATTTGGCGGCGCATGCTCGCCAATTCCGTTGTCCCAGTTGCCCGGAAACGTTCCACGTCGAATTCCTGCTCGATCGGCATATGCAGAGCCAGCATGGCGGCGTCAAGGATGgcaaacaggagcagcagggtGCCAACAGTGCGATGGGCAGTCTGTATGTGAATGCCTTGTTGCCACCgttggcggcggcagcagcggctgcggcagctgccacaaacaataacagtaaTCTGCATATTGATTACAATGTGGCGTTCAAGGGTCTGTTTGGAGGCggcaatgccacgcccaccaacACACAGCCAGCCAACAAGTTCTACAGTCCTTTGCAGGTGGATACAAGTGCGCTGAAGCCCCAACAGACGCCGCATCCCGCTCTGATGTACGGTCTCAGTCAGCGCTATTTGATGGAGATGTATGCGGCGAAGGCAACCTCGCCGGCGGCCAGTGCACCCGAGCTGCCGGCACAGGCAACCCAAGCGGCAAATGCGACGGCATCCAGCACGGGCAGCAGCTACAGTTGTGGCATGTGCGAGCGGCAGGATTTGCGCAGCGAGGCCGAACTGCATTCGCATCGCAAGTTGGCGCACAATCTGAAGACGGGCGTCAGTTTGAGATGTGCCTACTGTTCAGGTAACTACAAGTCGCGGgcggagctggagcagcacaTGAAGAGCTGCCACAATTCGAGTGGCAAGCACAAGTGTCTCATTTGCGACGAGATCTTTCCGTCGCCGGCGATACTCGCCGAGCACAAGTTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGTGCCCATTGtggccagcagctggagcatGTCGCCGCATTCCGTGCCCATCTCGGCGAGCATGGCAACGATGGTAATTTGCCGATGGCCTGCATTTGTTGCCGTCAAACCTTGCACTCGGAATTCGAGTTGAGTTTGCATGCCAAATTCCACACAAAATCACCGAGTTGTGGCAGCCTCCAGGAGCCCGTCTGTGCACTGTGCCTGGAACCCTTGCCGGGTGCGGGCGAAACCGCCAAGCTGTGCGAGAAATGTTGTCGCAAGCATAACCTGAATGGCAAACGCAACAAGGACGCAGCTGTGCCACcaccagctccagttccacCAGCTGCCAGCACAGTGGGCTATCTCGAGAATCGTTGTAATCTGTGCAAACTGATATTGCCACATGCCAAGAAACTGCAGGAGCATCTCGTGGAGCACACGTTTGCCGGCACCGAGCAGCGTGGTTTCAATTGCTACATTTGCTCGGCCGTCTTTACGGCACCCGGTGGCCTTTTGGCCCACATTGGGGAGCATGGTGCTCGGCCCTACGATTGCAATTTGTGCCCGGAGAAGTTTTACTTTCGTGCCGAGCTCGAGCATCATCAGCGTGCCCACGAACTAAGGCAAATCCTaacagccgctgctgctccgaCACGGCCCACAACCAAGCAGGAGACGCAGCACAGCTCGTCGGCCAGTTCACCCGTGCTCACGCTCAGTCCCAGTCATGTGAAGCAGGAGCTCTACGAATCAGAGGCAGCTAACTCACCGCAGCCCGACGAGGAGTCACCCGcccaggaggaggaggagtacATTGAGGTCGAGCAGATGCCACACGAGACCCGCTCCAACGAACTGGTCTCCACGGAGCGCTCCAGCAACAGCGCCTGA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSVQQQQLPKAAAEDNHSEESKANGEGPAAEQQDLAKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKEAKLATAGAAHGTGAAGGGGGGVAASKFDKLTGESIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGVTVPTTPTPTPLLRCSYCSPKVTEFSSLEQLNAHLQAAHEQQQQPGARSSTATSRETTVETVEPATNGFQLSCEYCTMKFGNIAALFQHMRTTHLDRLSSPNSYYEHFNRLATAGTFSPRLDMAKIKQDLPSPPAEELPTDLSSNKRRALTPPAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLISSSEFNCGASCGKSFAKSEELQQHLISEHVQTLLKCVICSELCENRMSMQLHLACAHSQETKLLRCSACLELFRNDTDFHVHVKTRHQLVGGGAAGGAVGGPPTAPPANPLQCMFCRAVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDGKQEQQGANSAMGSLYVNALLPPLAAAAAAAAAATNNNSNLHIDYNVAFKGLFGGGNATPTNTQPANKFYSPLQVDTSALKPQQTPHPALMYGLSQRYLMEMYAAKATSPAASAPELPAQATQAANATASSTGSSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRNKDAAVPPPAPVPPAASTVGYLENRCNLCKLILPHAKKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLAHIGEHGARPYDCNLCPEKFYFRAELEHHQRAHELRQILTAAAAPTRPTTKQETQHSSSASSPVLTLSPSHVKQELYESEAANSPQPDEESPAQEEEEYIEVEQMPHETRSNELVSTERSSNSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00514332;
80% Identity: -