Basic Information

Insect: Drosophila trichaetosa
Gene Symbol: L
Assembly: GCA_035043205.1
Location: JAWNNE010000025.1:1259112-1267949[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.0007 19.9 2.9 1 23 168 190 168 190 0.98

2 17 0.37 24 5.6 6.2 1 23 196 218 196 218 0.97

3 17 1.8e-07 1.2e-05 25.5 3.2 1 23 224 246 224 246 0.99

4 17 1.3e-05 0.00086 19.6 0.4 1 23 252 274 252 274 0.99

5 17 0.12 8.3 7.1 0.1 2 23 348 373 347 373 0.92

6 17 0.001 0.067 13.7 0.7 2 23 406 428 405 428 0.96

7 17 0.029 1.9 9.1 0.7 1 23 493 515 493 515 0.97

8 17 0.0054 0.36 11.4 0.1 2 23 523 544 522 544 0.91

9 17 0.00022 0.014 15.8 0.1 1 23 552 576 552 576 0.93

10 17 5.3 3.5e+02 2.0 1.6 2 23 612 634 611 634 0.95

11 17 0.0026 0.18 12.4 1.1 1 23 684 707 684 707 0.97

12 17 0.0067 0.44 11.1 1.6 2 23 881 903 880 903 0.96

13 17 0.12 7.9 7.1 0.1 1 23 909 931 909 931 0.92

14 17 0.57 38 5.0 0.4 2 23 939 960 938 960 0.93

15 17 0.67 44 4.8 0.6 2 23 1059 1080 1059 1080 0.94

16 17 0.039 2.6 8.7 0.0 1 23 1090 1112 1090 1112 0.94

17 17 0.00023 0.015 15.7 1.2 1 23 1117 1139 1117 1139 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.0007	19.9	2.9	1	23	168	190	168	190	0.98
2	17	0.37	24	5.6	6.2	1	23	196	218	196	218	0.97
3	17	1.8e-07	1.2e-05	25.5	3.2	1	23	224	246	224	246	0.99
4	17	1.3e-05	0.00086	19.6	0.4	1	23	252	274	252	274	0.99
5	17	0.12	8.3	7.1	0.1	2	23	348	373	347	373	0.92
6	17	0.001	0.067	13.7	0.7	2	23	406	428	405	428	0.96
7	17	0.029	1.9	9.1	0.7	1	23	493	515	493	515	0.97
8	17	0.0054	0.36	11.4	0.1	2	23	523	544	522	544	0.91
9	17	0.00022	0.014	15.8	0.1	1	23	552	576	552	576	0.93
10	17	5.3	3.5e+02	2.0	1.6	2	23	612	634	611	634	0.95
11	17	0.0026	0.18	12.4	1.1	1	23	684	707	684	707	0.97
12	17	0.0067	0.44	11.1	1.6	2	23	881	903	880	903	0.96
13	17	0.12	7.9	7.1	0.1	1	23	909	931	909	931	0.92
14	17	0.57	38	5.0	0.4	2	23	939	960	938	960	0.93
15	17	0.67	44	4.8	0.6	2	23	1059	1080	1059	1080	0.94
16	17	0.039	2.6	8.7	0.0	1	23	1090	1112	1090	1112	0.94
17	17	0.00023	0.015	15.7	1.2	1	23	1117	1139	1117	1139	0.97

Sequence Information

Coding Sequence: ATGATGGCCTTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGGagaatttgattgaaaagaTTCAGGCCACAAAGGAGATTACAAATAACGATATGTACAGCACGCACACCTCGTCGAGCTACTCGCCCAGCATCTCGGATGGCACATTGACGCCCAACTCggtacagcagcagcagctggccaagGCTGCCTCCGAGGACAATCACAGCGAGGAGTCCAAGGCAAATGGTGAGGGTCCTGGTGCGGAGCAACAGGATCTGACCAAGCCGAAGCGACCCGCTCatttgcatcatcatcatcatcatcattatcatcatcagcaggcGCTGAAAATTGCCAACAAGTTGCGCAAAATCAATAAGGAAGCCAAGTTGGCAACCGCAGGAGCCGCACATGGCACaggagcaacaggagcaggaggtggAGGCGGTGGAGTTGCCGCCAGCAAGTTTGATAAGTTGACAGGCGAGGGAATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCACGTCCAGaGCCATGCCGAACATTTGCCTTTCAAGTGCGAATACTGCGCCAAGCTGTTCAAGCATAAGCGATCCCGAGATCGCCACAAGAAGCTGCACACCAACGAGAGGAACTACAAGTGTCCGCATTGCGAGGCTGCTTTCTCCAGAAGCGATCATTTAAAGATTCACATGAAGACGCACGATATACAGAAGCCGTTCCAGTGCAGCATGTGCAATCGTGGCTATAATACTGCCGCCGCGTTGACCTCCCACATGCAGAAGCACAAGAAGAATGCTGCCATTCTGGCAGCTGGTGGCAATCCCAATGCCCTCAATTATAGTCCACGCTCGACGGGATCGGCGTCCATCTCGAGCAATGGCAGCTTGCACAAGCGACGCTACGCTTTGGCACTCGCCTCGGACAGCAGTCCGAGTCGGCTGGAGTTCCCCAAGCGGGCACGTGGTGTCACTGTGccgaccacgcccactccaaCGCCCCTGCTCAGATGCAGTTACTGCAGTCCCAAGGTGACCGAGTTTAGCAGCCTGGAACAGTTGAATGCCCATCTGCAGGCGGCAcacgaacagcaacagcagccgggTGCAAGGAGCTCAACAGCCACCAGCAGAGAGACCACAGTGGAGACAGTGGAGCCTCCCACGAATGGTTTTCAGCTCAGCTGCGAATATTGCACAATGAAATTCGGCAATATTGCAACACTCTTTCAGCACATGCGCAGCACTCACTTGGATCGCCTGAGCAGTCCCAATTCGTATTATGAGCACTTTAATCGTTTGGCCACCGCGGGCACATTTAGTCCACGGTTGGAGATGCCCAAGATCAAGCAGGATTTGCCGAGTCCGCCGGCAGAGGAGCTGCCAACGGATCTGAGCAGCAATAAGCGACGAGCGCTGACGCCGCCAGCGCCACCTGGCGTCTTCTTTTGCAATCAGTGCAACGCAGGGTTGCCAGACTTTGAGAGTTTTCGCAATCATCTAAAGACGCACATCGCGGAGGGCATGCAACTGATATGCCCCCACTGCGGATTGAGTCTGCCGGAGCAGAGTGAATTCGAGCGACATGTTGTCGCCCACTTCCTGATCACCAGCTCCGAGTTCAATTGCGGCGCCAGCTGTGGCAAGTCGTTTGCCAAATCGGAGGAACTGCAACAGCATCTGATCAGCGAACATGTCCAGACGCTGCTCAAGTGTGCGATCTGCTCGGAGCTGTGCGAGAATCGCATGTCCATGCAGCTCCATTTGGCCTGTGCCCACAGTCAGGAGTCGAAGCTGCTCCGTTGCAGCGCCTGCCTGGAACTCTTTCGCAACGATACGGATTTTCATGTGCATGTCAAGACGCGACATCAACTGGTAGGCGGCAATGCTTCTGGTGGAGCAGTTGGAGGACCACCCAATGCTTCGCCAGCCAATCCGTTGCAGTGCATGTTTTGTCGCGCTGTTTGCGCCTCGGAGCTGgaaatgcatttccatttggcGGCCCATGCGCGCCAATTCCGTTGTCCCAGTTGCCCGGAAACGTTCCACGTGGAGTTCCTGCTCGATCGGCATATGCAGAGCCAGCATGGCGGCGTCAAGGATGGCAAGCAGGAGCAACAGGGCGCCAATAATTCGATGGGCAGTCTTTATGTGAATGCCTTGTTGCCACCgttggcggcggcagcagcggctgcagcagctgccacaaataataacagtaatcTGCACATTGATTACAATGTGGCATTCAAGGGTCTGTTTGGAGGCggcaatgccacgcccaccaacACACAGCCAGCCAACAAGTTCTACAGCCCCTTACAGGTGGATACCAGTGCGCTGAAGCCCCAACAAACGCCGCATCCGGCACTCATGTATGGTCTGAGTCAGCGCTATTTGATGGAGATGTATGCGGCGAAGGCAACATCGCCGGCGGCCAGTGCACCCGAGCTGCCGGCACAGGCAACCCAAGCGGCAAATGCGGCGGCATCCAGCACGGGCAGCAGTTACAGTTGTGGCATGTGCGAGCGACAGGATTTGCGCAGTGAGGCTGAACTCCATTCGCATCGCAAGTTGGCGCACAATCTGAAGACGGGTGTGAGTTTGAGGTGTGCCTACTGCTCGGGCAATTACAAGTCGCGGgcggagctggagcagcacaTGAAGAGCTGCCACAATTCGAGTGGCAAGCACAAGTGTCTCATTTGCGACGAGATCTTTCCGTCGCCGGCGATACTCGCCGAGCACAAGTTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGTGCCCATTGTGGCCAGCAGTTGGAGCATGTCGCCGCATTCCGCGCCCATCTCGGCGAGCATGGCAACGATGGTAATTTGCCCATGGCCTGCATTTGTTGCCGTCAAACTTTGCACTCGGAATTCGAGTTGAGTTTGCATGCCAAATTCCACACCAAATCACCGAGTTGTGGCAGCCTCCAGGAGCCCGTGTGTGCGCTGTGCCTGGAACCCTTGCCGGGTGCTGGCGAAACCGCCAAGCTGTGTGAGAAATGTTGTCGCAAACATAACTTGAATGGCAAACGCAACAAGGATGCAGCTgtgccaccaccagcaccaccagcagcagcagccagcacagTGGGCTATCTCGAGAATCGTTGTAATCTCTGCAAGCTGATATTGCCACATGCCAAGAAACTGCAGGAGCATCTCGTAGAGCACACGTTTGCCGGCACCGAGCAGCGCGGTTATAATTGCTACATTTGCTCGGCGGTTTTTACGGCTCCCGGTGGCCTTTTGGCCCATATTGGGGAGCATGGTGCTCGACCCTACGATTGCAATTTGTGCCCGGAGAAGTTTTACTTTCGTGCCGAACTCGAGCATCATCAGCGTGCCCATGAGCTGAGGCAAATTCCAACAGCCGTTGCTGCTCCGACACGGCCCACACCCAAACAGGAGACTCGGCACAGCTCGTCGGCCAGTTCGCCCGTGCTCAGTCCCAGTCATGTGAAGCAGGAGCTCTACGAATCGGAGGCGGCGACCTCACCACAACCCGACGACGAGTCACCCGCcccggaggaggaggagtacATTGAGGTCGAGCAGATGCCACACGAGACCCGCTCCAACGAACTGGTCTCCACGGAGCGCTCCAGCAACAGCGCCTGA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSVQQQQLAKAASEDNHSEESKANGEGPGAEQQDLTKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKEAKLATAGAAHGTGATGAGGGGGGVAASKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGVTVPTTPTPTPLLRCSYCSPKVTEFSSLEQLNAHLQAAHEQQQQPGARSSTATSRETTVETVEPPTNGFQLSCEYCTMKFGNIATLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLEMPKIKQDLPSPPAEELPTDLSSNKRRALTPPAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLITSSEFNCGASCGKSFAKSEELQQHLISEHVQTLLKCAICSELCENRMSMQLHLACAHSQESKLLRCSACLELFRNDTDFHVHVKTRHQLVGGNASGGAVGGPPNASPANPLQCMFCRAVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDGKQEQQGANNSMGSLYVNALLPPLAAAAAAAAAATNNNSNLHIDYNVAFKGLFGGGNATPTNTQPANKFYSPLQVDTSALKPQQTPHPALMYGLSQRYLMEMYAAKATSPAASAPELPAQATQAANAAASSTGSSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRNKDAAVPPPAPPAAAASTVGYLENRCNLCKLILPHAKKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPGGLLAHIGEHGARPYDCNLCPEKFYFRAELEHHQRAHELRQIPTAVAAPTRPTPKQETRHSSSASSPVLSPSHVKQELYESEAATSPQPDDESPAPEEEEYIEVEQMPHETRSNELVSTERSSNSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00514332;
80% Identity: -