Basic Information

Insect: Drosophila silvestris
Gene Symbol: L
Assembly: GCA_035043445.1
Location: JAWNMZ010000170.1:3308739-3318632[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1e-05 0.00068 19.9 2.9 1 23 157 179 157 179 0.98

2 17 0.35 23 5.6 6.2 1 23 185 207 185 207 0.97

3 17 1.7e-07 1.1e-05 25.5 3.2 1 23 213 235 213 235 0.99

4 17 1.3e-05 0.00083 19.6 0.4 1 23 241 263 241 263 0.99

5 17 0.12 8 7.1 0.1 2 23 337 362 336 362 0.92

6 17 0.00042 0.028 14.8 0.4 2 23 395 417 394 417 0.96

7 17 0.028 1.8 9.1 0.7 1 23 482 504 482 504 0.97

8 17 0.0052 0.34 11.4 0.1 2 23 512 533 511 533 0.91

9 17 0.00021 0.014 15.8 0.1 1 23 541 565 541 565 0.93

10 17 5.2 3.4e+02 2.0 1.7 2 23 601 623 600 623 0.95

11 17 0.0026 0.17 12.4 1.1 1 23 673 696 673 696 0.97

12 17 0.0065 0.43 11.1 1.6 2 23 870 892 869 892 0.96

13 17 0.12 7.7 7.2 0.1 1 23 898 920 898 920 0.92

14 17 0.56 37 5.0 0.4 2 23 928 949 927 949 0.93

15 17 0.65 43 4.8 0.6 2 23 1048 1069 1048 1069 0.94

16 17 0.024 1.6 9.3 0.0 1 23 1079 1101 1079 1101 0.96

17 17 0.00022 0.015 15.7 1.2 1 23 1106 1128 1106 1128 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1e-05	0.00068	19.9	2.9	1	23	157	179	157	179	0.98
2	17	0.35	23	5.6	6.2	1	23	185	207	185	207	0.97
3	17	1.7e-07	1.1e-05	25.5	3.2	1	23	213	235	213	235	0.99
4	17	1.3e-05	0.00083	19.6	0.4	1	23	241	263	241	263	0.99
5	17	0.12	8	7.1	0.1	2	23	337	362	336	362	0.92
6	17	0.00042	0.028	14.8	0.4	2	23	395	417	394	417	0.96
7	17	0.028	1.8	9.1	0.7	1	23	482	504	482	504	0.97
8	17	0.0052	0.34	11.4	0.1	2	23	512	533	511	533	0.91
9	17	0.00021	0.014	15.8	0.1	1	23	541	565	541	565	0.93
10	17	5.2	3.4e+02	2.0	1.7	2	23	601	623	600	623	0.95
11	17	0.0026	0.17	12.4	1.1	1	23	673	696	673	696	0.97
12	17	0.0065	0.43	11.1	1.6	2	23	870	892	869	892	0.96
13	17	0.12	7.7	7.2	0.1	1	23	898	920	898	920	0.92
14	17	0.56	37	5.0	0.4	2	23	928	949	927	949	0.93
15	17	0.65	43	4.8	0.6	2	23	1048	1069	1048	1069	0.94
16	17	0.024	1.6	9.3	0.0	1	23	1079	1101	1079	1101	0.96
17	17	0.00022	0.015	15.7	1.2	1	23	1106	1128	1106	1128	0.97

Sequence Information

Coding Sequence: ATGATGGCCTTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGGAGAATTTGATTGAAAAGATTCAGGCCACAAAGGAGATTACAAATAACGaCATGTACAGCACGCACACCTCGTCGAGCTACTCGCCCAGCATCTCGGATGGCACATTGACGCCCAACtcggtgcagcagcagcagcagctgcccaagGCTGCCTCCGAGGACAATCATTGCGGAGAGTCGAAGGCAAATGGTGAGGGTCCTGCTGCGGAGCAACAGGATCTGGCCAAGCCGAAGCGACCCGCTCatttgcatcatcatcatcatcatcattatcatcatcagcaggcgctgaaaattgccaacaagctgcgcaaaatcaataaagaaGCCAAGTTGGCAACCGCAGGAGCAGCACATGGAACAGgcgcagcaggagcagcaggtgGCGGAGGCGAAAGCATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCACGTCCAGAGCCATGCCGAACATTTGCCTTTCAAGTGCGAATACTGCGCCAAGCTGTTCAAGCACAAGCGATCCCGAGATCGCCACAAGAAGCTGCACACAAACGAGAGGAACTACAAGTGTCCGCACTGCGAGGCTGCTTTCTCCAGAAGCGATCATTTAAAGATTCACATGAAGACGCACGACATACAGAAGCCGTTCCAGTGCAGCATGTGCAATCGTGGCTATAATACTGCTGCCGCTTTGACCTCGCACATGCAGAAGCACAAGAAGAATGCGGCAATACTGGCAGCTGGTGGCAATCCCAATGCTTTGAATTACAGTCCACGCTCGACGGGATCGGCGTCCATCTCGAGCAATGGCAGTTTGCACAAGCGACGCTATGCTTTGGCGCTCGCCTCCGACAGCAGTCCGAGTCGTCTGGAGTTCCCCAAGCGGGCACGCGGTGTTACCGTGccgaccacgcccactccaaCGCCCCTGCTGCGCTGCAGTTACTGCAGTCCCAAGGTGACCGAGTTTAGCAGCCTGGAACAGTTGAATGCCCATCTGCAGGCGGCAcacgaacagcaacagcagccgggCGCAAGGAGTTCGACGGCCACCAGCAGAGAGACCACAGTGGAGACCGTGGAGCCACCGACGAATGGTTTCCAGCTCAGCTGCGAATATTGCACAATGAAATTCGGAAATATTGCGGCACTCTTCCAGCACATGCGCACCACGCACTTGGATCGCCTGAGCAGTCCCAATTCGTATTACGAGCACTTTAATCGTTTGGCCACCGCGGGCACATTCAGTCCACGCTTGGATATGCCCAAGATCAAGCAGGATTTGCCGAGCCCGCCGGCGGAGGAGCTGCCAACGGATCTGAGCAGCAATAAGCGACGAGCGTTGACGCCGCCAGCGCCACCTGGCGTCTTCTTTTGCAACCAGTGCAACGCAGGGTTGCCAGACTTTGAGAGCTTTCGCAATCATCTGAAGACGCACATTGCGGAAGGCATGCAACTGATATGCCCCCACTGCGGATTGAGTCTGCCGGAGCAGAGTGAATTCGAGCGACATGTTGTCGCCCACTTCCTGATCAGCAGCTCCGAGTTCAATTGCGGCGCCAGTTGTGGCAAATCGTTTGCCAAATCGGAGGaactgcaacagcatctgATCAGCGAACATGTCCAGACGCTGCTCAAGTGTGTGATCTGCTCGGAGCTGTGCGAGAATCGCATGTCCATGCAGCTCCACTTGGCCTGTGCCCACAGCCAGGAGACGAAGCTGCTCCGTTGCAGCGCCTGCTTGGAACTCTTTCGCACCGATACGGATTTCCATGTGCATGTCAAGACGCGTCATCAACTGGTGGGCGGCAGTGCTGCTGGCGGAGCAGTTGGCGGACCACCCACTGCGCCACCTGCCAATCCGTTGCAGTGCATGTTCTGTCGCGCTGTTTGCGCCTCGGAGCTGGAAATGCACTTCCATTTGGCGGCGCATGCTCGCCAATTCCGTTGTCCCAGTTGCCCGGAAACGTTCCACGTCGAATTCCTGCTCGATCGGCATATGCAGAGCCAGCATGGCGGCGTCAAGGATGGcaaacaggagcagcagggtGCCAACAATTCGATGGGCAGTCTGTATGTGAATGCCTTGTTGCCACCgttggcggcggcagcagcggctgcggcagctgccacaaacaataacagtaatCTGCATATTGATTACAATGTGGCGTTCAAGGGTCTGTTTGGAGGCggcaatgccacgcccaccaacACACAGCCAGCCAACAAGTTCTACAGTCCTTTGCAGGTGGATACAAGTGCGCTGAAGCCCCAACAGACGCCGCATCCCGCTCTGATGTACGGTCTCAGTCAGCGCTATTTGATGGAGATGTATGCGGCGAAGGCAACCTCGCCGGCGGCCAGTGCACCCGAGCTGCCGGCACAGGCAACCCAAGCGGCAAATGCGACGGCATCCAGCACGggcagcagctacagctgtGGCATGTGCGAGCGCCAGGATTTGCGCAGCGAGGCCGAACTGCATTCGCATCGCAAGTTGGCGCACAATCTGAAGACGGGCGTCAGTTTGAGATGTGCCTACTGTTCGGGTAACTACAAGTCGCGGgcggagctggagcagcacatGAAGAGCTGCCACAATTCGAGTGGCAAGCACAAGTGTCTCATTTGCGACGAGATCTTTCCGTCGCCGGCGATACTCGCCGAGCACAAGTTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGTGCCCACTGtggccagcagctggagcatGTCGCCGCATTCCGTGCCCATCTCGGCGAGCATGGCAACGATGGCAATTTGCCCATGGCCTGCATTTGTTGCCGCCAAACTTTGCACTCGGAATTCGAGTTGAGTTTGCATGCGAAATTCCACACAAAATCACCGAGTTGTGGCAGCCTCCAGGAGCCCGTCTGTGCTCTATGCCTGGAACCCTTGCCGGGTGCGGGCGAAACCGCCAAGCTGTGTGAGAAATGTTGTCGCAAACACAACCTGAATGGCAAACGCAACAAGGACGCAGCTgtgccaccaccagcaccagcccCACCAGCAGCCAGCACAGTGGGCTATCTCGAGAATCGTTGCAATCTGTGCAAACTGATATTGCCGCATGCCAAGAAACTGCAGGAGCATCTCGTGGAGCACACGTTTGCCGGCACCGAGCAGCGTGGCTTCAATTGCTACATTTGCTCGGCGGTTTTTACGGCACCCGGTGGCCTTTTGGCCCACATTGCGGAGCACGGTGCTCGTCCCTACGATTGCAATTTGTGCCCGGAAAAGTTTTACTTTCGTGCCGAGCTCGAGCATCATCAGCGTGCCCACGAACTAAGGCAAATCCCAACAGCCGCTGCAGCTCCGACACGGCCCACAACCAAGCAGGAGACGCAGCACAGCTCGTCGGCCAGCTCACCCGTGCTCACGCTCAGTCCCAGTCATGTGAAGCAGGAGCTCTACGAATCGGAGGCGGCTAACTCACCACAGCCCGACGAGCAGTCACCCGcccaggaggaggaggagtacATTGAGGTCGAGCAGATGCCACATGAGACCCGCTCCAACGAACTGGTCACCACGGAACGCTCCAGCAACAGCGCCTGA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSVQQQQQLPKAASEDNHCGESKANGEGPAAEQQDLAKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKEAKLATAGAAHGTGAAGAAGGGGESIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGVTVPTTPTPTPLLRCSYCSPKVTEFSSLEQLNAHLQAAHEQQQQPGARSSTATSRETTVETVEPPTNGFQLSCEYCTMKFGNIAALFQHMRTTHLDRLSSPNSYYEHFNRLATAGTFSPRLDMPKIKQDLPSPPAEELPTDLSSNKRRALTPPAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLISSSEFNCGASCGKSFAKSEELQQHLISEHVQTLLKCVICSELCENRMSMQLHLACAHSQETKLLRCSACLELFRTDTDFHVHVKTRHQLVGGSAAGGAVGGPPTAPPANPLQCMFCRAVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDGKQEQQGANNSMGSLYVNALLPPLAAAAAAAAAATNNNSNLHIDYNVAFKGLFGGGNATPTNTQPANKFYSPLQVDTSALKPQQTPHPALMYGLSQRYLMEMYAAKATSPAASAPELPAQATQAANATASSTGSSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRNKDAAVPPPAPAPPAASTVGYLENRCNLCKLILPHAKKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLAHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRQIPTAAAAPTRPTTKQETQHSSSASSPVLTLSPSHVKQELYESEAANSPQPDEQSPAQEEEEYIEVEQMPHETRSNELVTTERSSNSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00514332;
80% Identity: -