Basic Information

Insect: Drosophila multiciliata
Gene Symbol: L
Assembly: GCA_037043605.1
Location: JBAMBF010000578.1:3219175-3229889[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1e-05 0.00068 19.9 2.9 1 23 173 195 173 195 0.98

2 17 0.35 23 5.6 6.2 1 23 201 223 201 223 0.97

3 17 1.7e-07 1.1e-05 25.5 3.2 1 23 229 251 229 251 0.99

4 17 1.2e-05 0.00083 19.6 0.4 1 23 257 279 257 279 0.99

5 17 0.12 8 7.1 0.1 2 23 354 379 353 379 0.92

6 17 0.00094 0.063 13.7 0.4 2 23 412 434 411 434 0.96

7 17 0.027 1.8 9.1 0.7 1 23 499 521 499 521 0.97

8 17 0.0051 0.34 11.4 0.1 2 23 529 550 528 550 0.91

9 17 0.00021 0.014 15.8 0.1 1 23 558 582 558 582 0.93

10 17 5.1 3.4e+02 1.9 1.6 2 23 618 640 617 640 0.95

11 17 0.0025 0.17 12.3 1.1 1 23 690 713 690 713 0.97

12 17 0.0064 0.43 11.1 1.6 2 23 887 909 886 909 0.96

13 17 0.11 7.6 7.1 0.1 1 23 915 937 915 937 0.92

14 17 0.55 37 5.0 0.4 2 23 945 966 944 966 0.93

15 17 0.64 43 4.8 0.6 2 23 1067 1088 1067 1088 0.94

16 17 0.048 3.2 8.3 0.0 1 23 1098 1120 1098 1120 0.94

17 17 0.00022 0.015 15.7 1.2 1 23 1125 1147 1125 1147 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1e-05	0.00068	19.9	2.9	1	23	173	195	173	195	0.98
2	17	0.35	23	5.6	6.2	1	23	201	223	201	223	0.97
3	17	1.7e-07	1.1e-05	25.5	3.2	1	23	229	251	229	251	0.99
4	17	1.2e-05	0.00083	19.6	0.4	1	23	257	279	257	279	0.99
5	17	0.12	8	7.1	0.1	2	23	354	379	353	379	0.92
6	17	0.00094	0.063	13.7	0.4	2	23	412	434	411	434	0.96
7	17	0.027	1.8	9.1	0.7	1	23	499	521	499	521	0.97
8	17	0.0051	0.34	11.4	0.1	2	23	529	550	528	550	0.91
9	17	0.00021	0.014	15.8	0.1	1	23	558	582	558	582	0.93
10	17	5.1	3.4e+02	1.9	1.6	2	23	618	640	617	640	0.95
11	17	0.0025	0.17	12.3	1.1	1	23	690	713	690	713	0.97
12	17	0.0064	0.43	11.1	1.6	2	23	887	909	886	909	0.96
13	17	0.11	7.6	7.1	0.1	1	23	915	937	915	937	0.92
14	17	0.55	37	5.0	0.4	2	23	945	966	944	966	0.93
15	17	0.64	43	4.8	0.6	2	23	1067	1088	1067	1088	0.94
16	17	0.048	3.2	8.3	0.0	1	23	1098	1120	1098	1120	0.94
17	17	0.00022	0.015	15.7	1.2	1	23	1125	1147	1125	1147	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGGAGAACTTGATTGAAAAGATTCAGGCCACAAAGGAGATTACAAATAACGACATGTACAGCACGCACACCTCGTCGAGCTACTCGCCCAGCATCTCGGATGGCACATTGACGCCCAACtcggtgcagcagcagcaactgctgcccaAGGCTGCCTCCGAGGATAATCACAGCGAAGAGTCGAAGGCAAATGGTGAGGGTCCTGGTGCGGAGCAACAGGATCTGGTCAAGCCGAAGCGACCCGCTCActtgcatcatcatcatcatcatcattatcatcatcagcaggcGCTGAAAATTGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAGTTGGCAACCGCAGGAGCAGCACATGGCACAGGAGCAGCTGGCGCAGGAGctggaggcggaggcggaggcggaggagTTGCCGCCAGCAAGTTTGATAAGTTGACAGGCGAGGGAATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCACGTCCAGaGCCATGCCGAACATTTGCCTTTCAAGTGCGAATACTGCGCCAAGCTGTTTAAGCACAAGCGATCCCGAGATCGCCACAAGAAGCTGCATACCAACGAGAGGAACTACAAATGTCCACATTGCGAGGCTGCTTTCTCCAGAAGCGATCATTTAAAGATTCACATGAAGACGCACGATATACAAAAGCCTTTCCAGTGCAGCATGTGCAATCGTGGCTATAATACTGCTGCCGCTTTGACCTCCCACATGCAGAAGCACAAGAAGAATGCCGCAATTCTGGCAGCTGGTGGCAATCCCAATGCCTTGAATTACAGTCCACGCTCGACGGGATCGGCGTCCATCTCGAGCAATGGCAGCTTGCACAAGCGACGCTATGCTTTGGCGCTCGCCTCGGACAGCAGTCCGAGTCGTCTGGAGTTCCCCAAGCGGGCACGTGGTGTCACCACCGTGCCGACCACGCCCACGCCAACGCCCCTGCTCAGATGCAGCTACTGCAGTCCCAAGGTGACCGAGTTCAGCAGCCTGGAACAGTTGAATGCCCATCTGCAGGCGGCACacgaacagcaacagcagccgggCGCCAGGAGCTCCACAGCCACCAGCAGAGAGACCGCGGTGGACACAGTGGAGCCTGCCACGAATGGTTTCCAGCTGAGCTGCGAATATTGCACAATGAAATTTGGAAATATTGCTGCACTTTTTCAGCACATGCGCAGCACCCACTTGGATCGGCTGAGCAGTCCCAATTCGTATTATGAGCACTTTAATCGCTTGGCCACCGCGGGCACGTTTAGTCCACGCTTGGAGATGCCCAAGATCAAGCAGGATTTGCCGAGTCCGCCGGCGGAGGAGCTGCCAACGGATCTGAGCAGCAATAAGCGACGAACATTGACGCCGCCAGAGCCACCTGGCGTCTTCTTCTGCAACCAGTGCAACGCAGGGTTGCCAGACTTTGAGAGTTTCCGCAATCATCTCAAGACGCACATTGCGGAGGGCATGCAACTGATATGCCCCCACTGCGGACTGAGTCTGCCGGAGCAGAGTGAATTCGAGCGACATGTTGTCGCCCATTTCCTGATCACCGGCTCCGAGTTCAATTGCGGAGCCAGCTGTGGCAAATCATTTGCCAAGTCGGAGGAACTGCAACAGCATCTGATCAGCGAGCATGTGCAGACGCTGCTCAAGTGTGCGATCTGCTCGGAGCTGTGCGAGAATCGCATGTCCATGCAGCTCCATCTGGCCTGTGCCCACAGCCAGGAGACGAAGCTGCTGCGTTGCAGCGCCTGTTTGGAACTCTTTCGCAACGATACCGATTTCCATGTGCATGTCAAGACGCGACATCAGCTGGTGGGCGGAAGTGCTTCTGGCGGATCAGTTGGTGGACCACCCACTGCGCCACCTGCTAATCCCTTGCAGTGCATGTTTTGTCGCGCCGTTTGCTCGTCGGAGCTGGaaatgcatttccatttggcGGCGCACGCTCGCCAATTCCGTTGTCCCAGTTGCCCGGAAACGTTCCACGTGGAATTCCTGCTCGATCGGCATATGCAGAGCCAGCATGGCGGTGTCAAGGAGAgcaagcaggagcagcagagtGCCAACAATTCGATGGGCAGTCTTTATGTGAATGCCTTGTTGCCACCATTGGCGGCGGCCGCAgcggctgcggcagctgcaacaaacaacaacagtaatttGCACATTGATTACAATGTGGCATTCAAGGGCTTGTTTGGAGGAGgaaatgccacgcccaccaacACACAGCCAGCCAACAAGTTCTACAGTCCTTTGCAGGTGGATACAAGTGCGCTGAAGCCCCAACAGACGCCGCATCCCGCGCTGATGTACGGACTCAGTCAGCGCTATTTGATGGAGATGTATGCGGCAAAGGCCACATCGCCGGCGGCCAGTGCACCCGAGCTGCCGGCACAGGCAACCCAAGCGGCAAATGCGACGGCATCCAGCACGGGCAGCAGCTACAGTTGTGGCATGTGCGAGCGGCAGGATCTGCGGAGTGAGGCCGAGCTGCATTCACATCGCAAGTTGGCGCACAATCTGAAGACGGGTGTGAGTCTGAGATGTGCTTACTGCTCCGGCAACTACAAGTCGCGGgcggagctggagcagcacaTGAAGAGCTGCCACAATTCGAGTGGCAAGCACAAATGTCTCATTTGCGACGAGATATTTCCCTCGCCGGCGATTCTCGCCGAGCACAAGTTGCAGCACTCGAAGGTGGGTCAGTCGGGCAAGTGTGCCCATTGtgggcagcagctggagcatgTCGCCGCATTCCGTGCCCATCTCGGCGAGCATGGCAACGATGGCAATTTGCCCATGGCCTGCATTTGTTGTCGCCAAACTTTGCACTCGGAATTCGAGTTGAGTTTGCATGCCAAATTCCACACAAAATCACCAAGTTGTGGCAGCCTCCAGGAGCCCGTCTGTGCGCTGTGCCTGGAACCCTTGCCGGGTGCGGGTGAAACCGCCAAGCTGTGTGAGAAATGTTGTCGCAAGCATAACCTAAATGGCAAACGCAACAAGGATGCAGTGGTCCCCCCAcccgcaccaccaccaccagcagcagcaggaaacaCAGTGGGTTATCTCGAGAATCGTTGTAATCTGTGCAAGCTGATATTGCCACATGCCAAGAAACTGCAGGAGCACCTCGTGGAGCACACATTCGCCGGCACCGAGCAACGCGGTTTCAATTGCTACATTTGCTCGGCGGTTTTCACGGCGCCCGGTGGTCTTTTGGCCCACATTGGGGAGCATGGTGCTCGACCCTACGACTGCAACTTGTGCCCGGAGAAGTTTTACTTTCGCGCCGAACTCGAGCATCATCAGCGTGCCCACGAACTGAGGCAAATCCCAGCAGCCGCCGCTGCTCCAACACGGCCCACAACCAAACAGGAGACTCAGCTCAGCTCGTCGGCCAGTTCACCCATTCTCACGCTGAGTCCCAGTCATGTGAAGCAGGAGCTCTACGAATCGGAGGCGGCAAACTCACCACAACCCGACGACGAGTCACCCGCCccagaggaggaggagtacaTTGAGGTGGAGCGAATGCCGCATGAGACCCGCTCCAATGAACTGGTCTCCGCGGAACGCTCCAGCAACAGCGCCTGA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSVQQQQLLPKAASEDNHSEESKANGEGPGAEQQDLVKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKEAKLATAGAAHGTGAAGAGAGGGGGGGGVAASKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGVTTVPTTPTPTPLLRCSYCSPKVTEFSSLEQLNAHLQAAHEQQQQPGARSSTATSRETAVDTVEPATNGFQLSCEYCTMKFGNIAALFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLEMPKIKQDLPSPPAEELPTDLSSNKRRTLTPPEPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLITGSEFNCGASCGKSFAKSEELQQHLISEHVQTLLKCAICSELCENRMSMQLHLACAHSQETKLLRCSACLELFRNDTDFHVHVKTRHQLVGGSASGGSVGGPPTAPPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKESKQEQQSANNSMGSLYVNALLPPLAAAAAAAAAATNNNSNLHIDYNVAFKGLFGGGNATPTNTQPANKFYSPLQVDTSALKPQQTPHPALMYGLSQRYLMEMYAAKATSPAASAPELPAQATQAANATASSTGSSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRNKDAVVPPPAPPPPAAAGNTVGYLENRCNLCKLILPHAKKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLAHIGEHGARPYDCNLCPEKFYFRAELEHHQRAHELRQIPAAAAAPTRPTTKQETQLSSSASSPILTLSPSHVKQELYESEAANSPQPDDESPAPEEEEYIEVERMPHETRSNELVSAERSSNSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01322853;
90% Identity: iTF_00514332;
80% Identity: -