Basic Information

Insect: Drosophila picticornis
Gene Symbol: L
Assembly: GCA_035043845.1
Location: JAWNMR010000493.1:3192951-3202568[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.00065 19.9 2.9 1 23 169 191 169 191 0.98

2 17 0.36 23 5.6 6.2 1 23 197 219 197 219 0.97

3 17 1.8e-07 1.1e-05 25.5 3.2 1 23 225 247 225 247 0.99

4 17 1.3e-05 0.0008 19.6 0.4 1 23 253 275 253 275 0.99

5 17 0.12 7.7 7.1 0.1 2 23 349 374 348 374 0.92

6 17 0.00043 0.027 14.8 0.4 2 23 407 429 406 429 0.96

7 17 0.029 1.8 9.1 0.7 1 23 494 516 494 516 0.97

8 17 0.0054 0.33 11.4 0.1 2 23 524 545 523 545 0.91

9 17 0.00022 0.013 15.8 0.1 1 23 553 577 553 577 0.93

10 17 5.3 3.3e+02 1.9 1.6 2 23 613 635 612 635 0.95

11 17 0.0026 0.16 12.4 1.1 1 23 685 708 685 708 0.97

12 17 0.0067 0.41 11.1 1.6 2 23 882 904 881 904 0.96

13 17 0.12 7.4 7.1 0.1 1 23 910 932 910 932 0.92

14 17 0.57 35 5.0 0.4 2 23 940 961 939 961 0.93

15 17 0.67 41 4.8 0.6 2 23 1060 1081 1060 1081 0.94

16 17 0.05 3.1 8.3 0.0 1 23 1091 1113 1091 1113 0.94

17 17 0.00023 0.014 15.7 1.2 1 23 1118 1140 1118 1140 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.00065	19.9	2.9	1	23	169	191	169	191	0.98
2	17	0.36	23	5.6	6.2	1	23	197	219	197	219	0.97
3	17	1.8e-07	1.1e-05	25.5	3.2	1	23	225	247	225	247	0.99
4	17	1.3e-05	0.0008	19.6	0.4	1	23	253	275	253	275	0.99
5	17	0.12	7.7	7.1	0.1	2	23	349	374	348	374	0.92
6	17	0.00043	0.027	14.8	0.4	2	23	407	429	406	429	0.96
7	17	0.029	1.8	9.1	0.7	1	23	494	516	494	516	0.97
8	17	0.0054	0.33	11.4	0.1	2	23	524	545	523	545	0.91
9	17	0.00022	0.013	15.8	0.1	1	23	553	577	553	577	0.93
10	17	5.3	3.3e+02	1.9	1.6	2	23	613	635	612	635	0.95
11	17	0.0026	0.16	12.4	1.1	1	23	685	708	685	708	0.97
12	17	0.0067	0.41	11.1	1.6	2	23	882	904	881	904	0.96
13	17	0.12	7.4	7.1	0.1	1	23	910	932	910	932	0.92
14	17	0.57	35	5.0	0.4	2	23	940	961	939	961	0.93
15	17	0.67	41	4.8	0.6	2	23	1060	1081	1060	1081	0.94
16	17	0.05	3.1	8.3	0.0	1	23	1091	1113	1091	1113	0.94
17	17	0.00023	0.014	15.7	1.2	1	23	1118	1140	1118	1140	0.97

Sequence Information

Coding Sequence: ATGATGGCCTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTGGAGAATTTGATAGAAAAGATTCAGGCTACAAAGGAGATTACAAATAACGACATGTACAGCACGCACACCTCGTCGAGCTACTCGCCCAGCATCTCGGATGGCACATTGACGCCCAACtcggtgcagcagcagcagctgcccaaGGCTGCCTCTGAGGACAATCATTCCGAGGAGTCCAAGGCAAATGGTGAGGGTCCTGCTGCGGAGCAACAGGATTTGGCCAAGCCGAAGCGACCCGCTCAtttgcatcatcatcatcatcatcattatcatcatcagcaggcgctgaaaattgccaacaagctgcgcaaaatcaataaagaaGCCAAGTTGGCAACCGCAGGAGCTGCACATGGAACAGGCGCAGCGGGAGCAGCCGGTGTTGGAGGTGGAGGAGTTGCCGCCAGCAAGTTTGATAAGTTGACAGGCGAAAGCATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTAAAGCATCACGTCCAGaGCCATGCCGAACATTTGCCTTTCAAGTGCGAATACTGCGCCAAGCTGTTCAAACACAAGCGATCCCGAGATCGCCACAAGAAGCTGCACACAAACGAGAGGAACTACAAGTGTCCGCACTGCGAGGCTGCTTTCTCCAGAAGCGATCATTTAAAGATTCACATGAAGACGCACGACATACAGAAGCCGTTCCAGTGCAGCATGTGCAATCGTGGCTATAACACTGCCGCCGCTTTGACCTCCCACATGCAGAAGCACAAGAAGAATGCTGCAATTCTGGCAGCTGGTGGCAATCCCAATGCTTTGAATTATAGTCCACGCTCGACGGGATCGGCGTCCATCTCGAGCAATGGCAGTTTGCACAAGCGACGCTATGCTTTGGCACTCGCCTCCGACAGCAGTCCGAGTCGCCTGGAGTTCCCCAAGCGGGCGCGTGGTGTTACCGTGccgaccacgcccactccaACGCCCCTGCTGCGCTGCAGTTACTGCAGTCCCAAGGTGACCGAGTTTAGCAGCCTGGAACAGTTGAATGCCCATTTGCAGGCGGCAcacgagcagcaacagcagccgggCGCAAGGAGTTCGACAGCCACCAGCAGAGAGACCACAGTGGACACAGTGGAGCCACCCACGAACGGTTTCCAGCTCAGCTGCGAGTATTGCACAATGAAATTCGGAAATATTGCGGCACTCTTCCAGCACATGCGCACCACTCACTTGGATCGCCTGAGCAGTCCCAATTCGTATTATGAGCACTTTAATCGTTTGGCCACCGCGGGCACATTTAGTCCACGCTTGGATATGCCCAAGATCAAGCAGGATTTGCCGAGTCCGCCGGCGGAGGAGCTGCCAACGGATCTGAGCAGCAATAAGCGACGAGCTTTGACGCCGCCAGCGCCACCTGGCGTCTTCTTTTGCAATCAGTGCAACGCAGGGTTGCCAGACTTTGAGAGTTTTCGCAATCATCTCAAGACGCACATTGCGGAAGGCATGCAACTGATATGCCCCCACTGCGGACTGAGTCTGCCGGAGCAGAGCGAGTTCGAGCGACATGTTGTCGCCCATTTCCTGATCAGCAGTTCCGAGTTCAACTGCGGCGCCAGTTGTGGCAAATCGTTTGCCAAATCGGAGGAACTGCAACAGCATCTGATCAGCGAACATGTCCAGACGCTGCTCAAGTGTGTGATCTGCTCGGAGCTGTGCGAGAATCGCATGTCCATGCAGCTCCACTTGGCCTGTGCCCACAGTCAGGAGACGAAGCTGCTCCGGTGCAGCGCCTGCTTGGAACTCTTTCGCAACGATACGGATTTCCATGTGCATGTCAAGACGCGACATCAACTGGTGGGCGGTAGTGCTGCTGGCGGAGCAGTTGGAGGACCACCCACTGCTCCACCTGCCAATCCGTTGCAGTGCATGTTCTGTCGCGCTGTGTGCGCCTCGGAGCTGGAAATGCACTTCCATTTGGCGGCGCATGCTCGCCAATTCCGTTGTCCCAGTTGCCCGGAAACGTTCCACGTGGAATTCCTGCTCGATCGGCATATGCAGAGCCAGCATGGTGGCGTCAAGGATGGcaaacaggagcagcagggtGCCAACAATGCGATGGGCAGTCTTTATGTGAATGCCTTGCTGCCACCcttggcggcggcagcagcggctgcggctgctgccacaaataataacagtaaTCTGCACATTGATTACAATGTGGCATTCAAGGGTCTGTTCGGAGGCggcaatgccacgcccaccaacACACAGCCAGCCAACAAGTTCTACAGTCCTTTGCAGGTGGATACAAGTGCGCTGAAGCCCCAACAGACGCCGCATCCCGCTCTGATGTACGGCCTCAGTCAGCGCTATTTGATGGAGATGTATGCGGCGAAGGCAACCTCGCCGGCGGCCAGTGCACCCGAGCTGCCGGCACAGGCAACCCAAGCGGCAAATGCAACCGCATCCAGCACTGGCAGCAGTTACAGTTGTGGCATGTGCGAGCGCCAGGATTTGCGCAGCGAGGCCGAACTGCATTCACATCGCAAGTTGGCGCACAATCTGAAGACGGGCGTCAGTTTGAGATGTGCCTACTGTTCAGGTAACTACAAGTCGCGGgcggagctggagcagcacaTGAAGAGCTGCCACAATTCGAGTGGCAAGCACAAGTGTCTCATTTGCGACGAGATATTTCCGTCGCCGGCGATACTCGCCGAGCACAAGTTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGTGCCCATTGTggccagcagctggagcaTGTCGCCGCATTCCGTGCCCATCTCGGCGAGCATGGCAACGATGGTAATTTGCCCATGGCCTGCATTTGTTGCCGTCAAACTTTGCACTCGGAATTCGAGTTGAGCTTGCATGCCAAATTCCACACAAAATCACCGAGTTGTGGCAGCCTCCAGGAACCCGTCTGCGCGCTGTGCCTGGAACCCTTGCCGGGTGCTGGCGAAACCGCCAAGCTGTGTGAGAAATGTTGTCGCAAACATAACCTGAATGGCAAACGCAACAAGGACGCAGCTgtgccaccaccagcaccagcccCACCAGCAGCCAGCACAGTGGGCTATCTCGAGAATCGATGTAATCTGTGCAAACTGATATTGCCACATGCCAAGAAACTGCAGGAGCATCTCGTGGAGCACACGTTTGCCGGCACCGAGCAGCGTGGTTTCAATTGCTACATTTGCTCGGCGGTTTTCACGGCACCCGGTGGCCTTTTGGCCCACATTGGGGAGCATGGTGCTCGACCCTACGATTGCAACTTGTGCCCGGAGAAGTTCTACTTTCGTGCCGAGCTCGAGCATCATCAGCGTGCCCACGAACTAAGGCAAATCCCAACAGCCGCTGCCGCTCCGACACGGCCCACAACCAAGCAGGAGACGCAGCACAGCTCGTCGGCCAGTTCACCCGTGCTCACACTCAGTCCCAGTCATGTGAAGCAGGAGCTCTACGAATCGGAGGCGGCAAACTCACCACAGCCCGACGAGCAGTCACCCGcccaggaggaggaggagtacATTGAAGTCGAACAGATGCCACACGAGACCCGCTCCAATGAACTGGTCTCCACGGAACGCTCCAGCAACAGCGCCTGA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSVQQQQLPKAASEDNHSEESKANGEGPAAEQQDLAKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKEAKLATAGAAHGTGAAGAAGVGGGGVAASKFDKLTGESIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGVTVPTTPTPTPLLRCSYCSPKVTEFSSLEQLNAHLQAAHEQQQQPGARSSTATSRETTVDTVEPPTNGFQLSCEYCTMKFGNIAALFQHMRTTHLDRLSSPNSYYEHFNRLATAGTFSPRLDMPKIKQDLPSPPAEELPTDLSSNKRRALTPPAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLISSSEFNCGASCGKSFAKSEELQQHLISEHVQTLLKCVICSELCENRMSMQLHLACAHSQETKLLRCSACLELFRNDTDFHVHVKTRHQLVGGSAAGGAVGGPPTAPPANPLQCMFCRAVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDGKQEQQGANNAMGSLYVNALLPPLAAAAAAAAAATNNNSNLHIDYNVAFKGLFGGGNATPTNTQPANKFYSPLQVDTSALKPQQTPHPALMYGLSQRYLMEMYAAKATSPAASAPELPAQATQAANATASSTGSSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRNKDAAVPPPAPAPPAASTVGYLENRCNLCKLILPHAKKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLAHIGEHGARPYDCNLCPEKFYFRAELEHHQRAHELRQIPTAAAAPTRPTTKQETQHSSSASSPVLTLSPSHVKQELYESEAANSPQPDEQSPAQEEEEYIEVEQMPHETRSNELVSTERSSNSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00514332;
80% Identity: -