Basic Information

Insect: Drosophila nigritarsus
Gene Symbol: L
Assembly: GCA_035044305.1
Location: JAWNMF010000125.1:6182490-6192096[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.0008 19.9 2.9 1 23 167 189 167 189 0.98

2 17 0.37 27 5.6 6.2 1 23 195 217 195 217 0.97

3 17 1.8e-07 1.3e-05 25.5 3.2 1 23 223 245 223 245 0.99

4 17 1.3e-05 0.00097 19.6 0.4 1 23 251 273 251 273 0.99

5 17 0.13 9.4 7.1 0.1 2 23 347 372 346 372 0.92

6 17 0.0024 0.18 12.5 0.4 2 23 405 427 404 427 0.95

7 17 0.029 2.1 9.1 0.7 1 23 492 514 492 514 0.97

8 17 0.0054 0.4 11.4 0.1 2 23 522 543 521 543 0.91

9 17 0.00022 0.016 15.8 0.1 1 23 551 575 551 575 0.93

10 17 5.4 4e+02 1.9 1.6 2 23 611 633 610 633 0.95

11 17 0.0027 0.2 12.4 1.1 1 23 683 706 683 706 0.97

12 17 0.0067 0.5 11.1 1.6 2 23 880 902 879 902 0.96

13 17 0.12 9 7.1 0.1 1 23 908 930 908 930 0.92

14 17 0.58 43 5.0 0.4 2 23 938 959 937 959 0.93

15 17 0.67 50 4.8 0.6 2 23 1060 1081 1060 1081 0.94

16 17 0.05 3.8 8.3 0.0 1 23 1091 1113 1091 1113 0.94

17 17 0.00023 0.017 15.7 1.2 1 23 1118 1140 1118 1140 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.0008	19.9	2.9	1	23	167	189	167	189	0.98
2	17	0.37	27	5.6	6.2	1	23	195	217	195	217	0.97
3	17	1.8e-07	1.3e-05	25.5	3.2	1	23	223	245	223	245	0.99
4	17	1.3e-05	0.00097	19.6	0.4	1	23	251	273	251	273	0.99
5	17	0.13	9.4	7.1	0.1	2	23	347	372	346	372	0.92
6	17	0.0024	0.18	12.5	0.4	2	23	405	427	404	427	0.95
7	17	0.029	2.1	9.1	0.7	1	23	492	514	492	514	0.97
8	17	0.0054	0.4	11.4	0.1	2	23	522	543	521	543	0.91
9	17	0.00022	0.016	15.8	0.1	1	23	551	575	551	575	0.93
10	17	5.4	4e+02	1.9	1.6	2	23	611	633	610	633	0.95
11	17	0.0027	0.2	12.4	1.1	1	23	683	706	683	706	0.97
12	17	0.0067	0.5	11.1	1.6	2	23	880	902	879	902	0.96
13	17	0.12	9	7.1	0.1	1	23	908	930	908	930	0.92
14	17	0.58	43	5.0	0.4	2	23	938	959	937	959	0.93
15	17	0.67	50	4.8	0.6	2	23	1060	1081	1060	1081	0.94
16	17	0.05	3.8	8.3	0.0	1	23	1091	1113	1091	1113	0.94
17	17	0.00023	0.017	15.7	1.2	1	23	1118	1140	1118	1140	0.97

Sequence Information

Coding Sequence: ATGATGGCCTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTGGagaatttgattgaaaagaTTCAGGCCACAAAGGAGATTACAAATAACGATATGTACAGCACGCACACCTCGTCGAGCTACTCGCCCAGCATCTCGGATGGCACATTGACGCCCAACTCggtacagcagcagcagctggccaagGCTGCCTCCGAGGACAATCACAGCGAAGAGTCCAAGGCAAATGGTGAGAGTCCTGCTGCGGAGCAACAGGATCTGACCAAGCCGAAGCGACCCGCTCAtttgcatcatcatcatcatcatcattatcatcatcagcaggcGCTGAAAATTGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAGTTGGCAACCGCAGGAGCCGCACATGGCACAGGAGcaggaggtggaggtggaggcAGTGGAGTTGCCGCCAGCAAGTTTGATAAGTTGACAGGCGAGGGAATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCACGTCCAGAGCCATGCCGAACATTTGCCTTTCAAGTGCGAATACTGCGCCAAGCTGTTCAAACATAAGCGATCCCGAGATCGCCACAAGAAGCTGCACACCAACGAGAGGAACTACAAGTGTCCGCATTGCGAGGCTGCTTTCTCCAGAAGCGATCATTTAAAGATTCACATGAAGACGCACGATATACAGAAGCCGTTCCAATGCAGCATGTGCAATCGTGGCTATAATACTGCTGCCGCGTTGACCTCCCACATGCAGAAGCACAAGAAGAATGCTGCCATTCTGGCAGCTGGTGGCAATCCCAATGCCCTCAATTATAGTCCACGCTCGACGGGATCGGCGTCCATCTCGAGCAATGGCAGCTTGCACAAGCGACGCTACGCTTTGGCACTCGCCTCGGACAGCAGTCCGAGTCGTCTGGAGTTCCCCAAGCGGGCACGTGGTGTCACTGTGCCGACAACGCCCACTCCAACGCCCCTGCTCAGATGCAGTTACTGCAGTCCCAAGGTGACCGAGTTTAGCAGCCTGGAACAGTTGAATGCCCATCTGCAGGCGGCAcacgaacagcaacagcagccgggTGCAAGGAGCTCAACAGCCACCAGCAGAGACACCACAGTGGAGGCAGTGGAACCTCCCACGAATGGTTTTCAGCTCAGCTGCGAATACTGCACAATGAAATTCGGAAATATTGCAACACTCTTTCAGCACATGCGCGGCACTCACTTGGATCGCCTGAGCAGTCCCAATTCGTATTATGAGCACTTTAATCGTTTGGCCACCGCGGGCACATTTAGTCCGCGTTTGGAGATGCCCAAGATCAAGCAGGATTTGCCGAGTCCGCCGGCAGAGGAGCTGCCAACGGATCTGAGCAGCAATAAGCGACGAGCGCTGACACCGCCAGCGCCACCTGGCGTCTTCTTTTGCAATCAGTGCAACGCAGGGTTGCCAGACTTTGAGAGTTTTCGCAATCATCTAAAGACGCACATTGCGGAGGGCATGCAACTGATATGCCCCCACTGCGGATTGAGTCTGCCGGAACAGAGTGAATTCGAGCGACATGTTGTCGCCCACTTCCTGATCACCAGCTCTGAGTTCAATTGCGGCGCCAGCTGTGGCAAGTCGTTTGCCAAATCGGAGGAGCTGCAACAGCATCTGATCAGCGAACATGTCCAGACGCTGCTCAAGTGTGCGATCTGTTCGGAGCTGTGCGAGAATCGCATGTCCATGCAGCTCCATTTGGCCTGTGCCCACAGTCAGGAGTCGAAGCTGCTCCGTTGCAGCGCCTGCCTGGAACTTTTTCGCAACGATACGGATTTTCATGTGCATGTCAAGACACGACATCAACTGGTCGGGGGCAGTGCTTCTGGGGGAGCAGTTGGGGGACCACCCAATGCTCCGCCAGCCAATCCGTTGCAGTGCATGTTTTGTCGCGCTGTTTGCGCCTCTGAGCTGGAAATGCATTTCCATTTGGCGGCCCATGCGCGCCAATTCCGTTGTCCCAGTTGCCCGGAAACGTTCCACGTGGAGTTCCTGCTCGATCGGCATATGCAGAGCCAGCATGGCGGCGTCAAGGATGGCAAGCAGGAGCAACAGGGCGCCAATAATTCGATGGGCAGTCTTTATGTGAATGCCTTGTTGCCACcgttggcggcggcggcagcggctgcggcagctgccacaaataataacagtaatCTGCACATTGATTACAATGTGGCATTCAAGGGTCTGTTTGGAGGCGgcaatgccacgcccaccaacACACAGCCAGCCAACAAGTTCTACAGTCCCTTACAGGTGGATACCAGTGCGCTGAAGCCCCAACAAACGCCGCATCCGGCACTCATGTACGGTCTGAGTCAGCGCTATTTGATGGAGATGTATGCGGCGAAGGCAACCTCGCCGGCGGCCAGTGCACCCGAGCTGCCGGCACAGGCAACCCAAGCGGCAAATGCGGCGGCATCCAGCACGGGCAGCAGTTACAGTTGTGGCATGTGCGAGCGACAGGATTTGCGGAGTGAGGCCGAACTCCATTCGCATCGCAAGTTGGCGCACAATCTGAAGACGGGTGTGAGTTTGAGGTGTGCCTACTGCTCGGGCAATTACAAGTCGCGGGcggagctggagcagcacaTGAAGAGCTGCCACAATTCGAGTGGCAAGCACAAGTGTCTCATTTGCGACGAGATCTTTCCGTCGCCGGCGATACTCGCCGAGCACAAGTTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGTGCCCATTGTggccagcagctggagcaTGTCGCTGCATTCCGTGCCCACCTCGGCGAGCATGGCAACGATGGTAATTTGCCCATGGCCTGCATTTGTTGCCGTCAAACTTTGCACTCGGAATTCGAGTTGAGTTTGCATGCGAAATTCCACACAAAATCACCGAGTTGTGGCAGCCTCCAGGAGCCCGTGTGTGCGCTGTGCCTGGAACCCTTGCCGGGTGCGGGCGAAACCGCCAAGCTGTGTGAGAAATGTTGTCGCAAACATAACTTGAATGGCAAACGCAACAAGGATGCAGCCGTGCCACCatcagcaccaccagcagcagcttcagcagcCAACACAGTGGGCTATCTCGAGAATCGTTGTAATCTCTGCAAGCTGATATTGCCACATGCCAAGAAACTGCAGGAGCATCTCGTGGAGCACACGTTTGCCGGCACCGAGCAGCGCGGTTTCAATTGCTACATTTGCTCGGCGGTTTTTACGGCATCCGGTGGACTTTTGGCACATATTGGGGAGCATGGTGCTCGACCATACGATTGTAATTTGTGCCCGGAGAAGTTTTACTTTCGTGCCGAACTCGAGCATCATCAGCGTGCCCATGAGCTGAGGCAAATTccagcagccgctgctgctccgGCAGCTGTGCGGGCCGTACCCAAACAGGAGACTCGGCACAGCTCGTCGGCCAGTTCGCCCGTTCTCAGTCCCAGTCATGTGAAGCAGGAGCTGTACGAATCGGAGGCGGCGAACTCACCACAACCCGACGACGAGTCACCCGCCccggaggaggaggagtacATTGAGGTCGAGCAGATGCCACACGAGACCCGCTCCAACGAACTGGTCTCCACGGAACGCTCCAGCAACAGCGCCTGA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSVQQQQLAKAASEDNHSEESKANGESPAAEQQDLTKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKEAKLATAGAAHGTGAGGGGGGSGVAASKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGVTVPTTPTPTPLLRCSYCSPKVTEFSSLEQLNAHLQAAHEQQQQPGARSSTATSRDTTVEAVEPPTNGFQLSCEYCTMKFGNIATLFQHMRGTHLDRLSSPNSYYEHFNRLATAGTFSPRLEMPKIKQDLPSPPAEELPTDLSSNKRRALTPPAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLITSSEFNCGASCGKSFAKSEELQQHLISEHVQTLLKCAICSELCENRMSMQLHLACAHSQESKLLRCSACLELFRNDTDFHVHVKTRHQLVGGSASGGAVGGPPNAPPANPLQCMFCRAVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDGKQEQQGANNSMGSLYVNALLPPLAAAAAAAAAATNNNSNLHIDYNVAFKGLFGGGNATPTNTQPANKFYSPLQVDTSALKPQQTPHPALMYGLSQRYLMEMYAAKATSPAASAPELPAQATQAANAAASSTGSSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRNKDAAVPPSAPPAAASAANTVGYLENRCNLCKLILPHAKKLQEHLVEHTFAGTEQRGFNCYICSAVFTASGGLLAHIGEHGARPYDCNLCPEKFYFRAELEHHQRAHELRQIPAAAAAPAAVRAVPKQETRHSSSASSPVLSPSHVKQELYESEAANSPQPDDESPAPEEEEYIEVEQMPHETRSNELVSTERSSNSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00514332;
80% Identity: -