Dcon014279.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila conformis
Gene Symbol
hang
Assembly
GCA_035041375.1
Location
JAWNLE010001151.1:6486444-6502447[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.38 25 5.6 1.0 3 23 512 533 511 533 0.93
2 17 0.64 41 4.9 3.6 3 22 640 659 638 659 0.89
3 17 0.00082 0.053 14.0 3.3 1 22 786 807 786 809 0.90
4 17 0.095 6.1 7.5 0.1 2 21 821 840 820 841 0.93
5 17 0.00095 0.062 13.8 0.2 2 23 973 995 972 995 0.95
6 17 0.0036 0.23 12.0 0.2 1 23 1003 1026 1003 1026 0.96
7 17 0.00021 0.014 15.9 0.2 2 23 1114 1135 1113 1135 0.97
8 17 0.00039 0.025 15.0 2.9 2 23 1240 1262 1239 1262 0.97
9 17 0.031 2 9.1 0.2 2 23 1271 1293 1270 1293 0.95
10 17 0.0018 0.12 12.9 0.3 1 23 1306 1329 1306 1329 0.97
11 17 0.00017 0.011 16.2 1.1 1 23 1388 1410 1388 1410 0.99
12 17 0.0027 0.17 12.4 0.9 1 23 1418 1441 1418 1441 0.96
13 17 0.093 6 7.6 0.4 2 19 1449 1466 1449 1467 0.94
14 17 3.6e-05 0.0023 18.3 0.4 3 23 1563 1583 1562 1583 0.98
15 17 0.00057 0.037 14.5 0.1 1 23 1618 1640 1618 1640 0.97
16 17 0.00081 0.053 14.0 0.6 2 23 1727 1749 1726 1749 0.93
17 17 0.0088 0.57 10.8 0.3 3 23 1805 1825 1805 1825 0.98

Sequence Information

Coding Sequence
ATGTGCGAcgctgccacaacaacaacaacagcagcagtaacaacaacaactgcagcagcacagGGAACAGGAGCAGCTGGCGATAATGCGATGGAAGAACAAAATCAGCGAGAGCGAAAAAGTTGCTGTCGCCTGTGCATTGCGCCCGCCAGCGAATGCATTTCGATCATCAACAGTTATGCGGCCGATAAGGAGCCGTTggccacaaaaatacaaaactgcgTAAATATCAAGATCACATCGGTGGATCGTCTATCGTTGCATATTTGCCATGCCTGCATCAGTTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCACAGTCGAAGCAGCGCCAGTGGCAAGAGACCGACAAAACCAAGCAGCAGACGCTACTCGGATACTTGGATTTGAACAGGGCCGAGAATGGCAACACCATtgaaccacaacaacaacaacaacaacagcagcagcagcagcacgaatTGAAAATGGATTCAGCGACGACTGCAGCTGAAAAGGCGTCCGCTGCCAACATTTTGGATGGCATACCTCAGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGtccaaagcaacagcagcaagcacagcaacaacagtcgcagcaacatacgcagcaacagcatgcAACAGGGGCAAGATCAACAGCGAAAACatcgacggcggcggcggcggtggcggagTCGCAACCAACATTGCAAACCCTTTTATTGCAGGtgcccacagcagcagcagcagcgacattGGCAACGGCGtcaacacagcaacagcagcgcaagcatcaacagcagcaacaccatcagcagcagcaacgtggCAAGCAGCCGCAACATCAGtaccatcaacagcagcagcagcatcgacaGAGTCGCGTTCGTCAACCGCGGCGACAGCAACAAGCGGCAACGGCCAAATTCAGGAGCAAATTGTTTATGCCACTGGATATATCGGTGCCAGCGCTGCCAGCGCTGTTGCCACCGCCGACgccagctgttgctgatgcagcGTCGTTGCTAttgccgctgtcgctgccactTGATTTTAGCCAGAATCCGAATCTAAATCCAAATCCCAATCAgtatccaaatccaaatcaaaaCTTAAATCAGAGATATACAAGTAGCCTTTTagtgccgccgccgctgccgctgtccGCGCCAGCTGCAACAATGAGCAGCAACGAGGCAGCCATTGCCACTGGCTGtggtgcaactgcaactgcaaccgcaGTCACGACTCCATTGCTCATGCCGCCGGTGCCTGCCGTGCCCATCAAGGATGAGCCCCTGTACGACACGGATGATGATTTTCAAATGAGGTCCATAGACGAATCCGATGATTTGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAAGGCGATGTGCCACTaaatACCTCTGACTATGATTATACGGCTCAGCATGGCGTGACCGCGGctgtggcggcggcagcaCTGCCCGCCAGCGCTGTGGCAAATGTGGCAGCCGCTGGGGACTCGAAGGTGGCCAGCTGCCGGGCGTGCAGTCTACAGTTCTCGACGCGGGCCAACGCTCGTCGCCACGAGCGCAATCTGCATCCGAATCTGTTCCAATTGTCGACAGACTCACCAAATAATACGCCGATCACAAAACCAACGCCGGCCCTCGCCGCCGCCTTGGAGATACAGCgcgcagcggcggcggcaaccgCAACCGCTGAGGCAACCCGTGCCGCTGCCGGTGGCAATATATCGGCCCAAAAATATCGACAGGTGGTGATGAACACGTTCACCAAATGCGAGAACGGTGGCTTCGACTACGACAATCCCGAACAGTATCAGCAACTGTTGTCCCACGACAAGGTCGACTTCATCCAAAAGAACACCGAATTTCTCGAACAGTACCAGACGATGACGTGTCGCTGTTGCAACAAGTTCTTCAACACGTACAAGAACTTTATGGCGCACGTGCGCAAAAAGTATCCGTTGCTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTCAACGCACTGCGCACCAAACAGCCAAACTTTGTCCATGCCAATGCCGCCTCATCCACTGCCACCACATCAACGACAGCTGCGGCGACTGCTctaaaccagcagcagcaacagatgaTGGCAGCAAacgaaacagcagcagaaacaacaacagcgacaacaacaacgccaacaacaccaacaacaccaacaacaacaccatcaaCACCATCAACGGATCGTACGGAGAAGTTGCGTGCCAAGGATCTGCTGGTTAACAAGCTGTACGAGTGCAAGCTGTGCCCAAAGGGTTTCCGCACAAAGCACGAGTTCCGCACCCATGTCTACGATAAGCATGCGGATGTGCAACGCAAAGATAACAATTCGATACAGTGCAGCTTCTGTGGCCTGGACTTTGCCGATCCGGTGGATCGTCGAAGGCATTACAATAACATGGATTGCATTGTGCGGCTGCGCTGCATGACTTGCGATGCCAAACTGGAGACGCATCAGCGCTTCCTCGAACATGTCTATCAGGATCATTTGGGTGGCGTGAGCAGTGATAATGCGTCCCAGCGCAGTTTGCTCGGCTCTCTTGGCATCGGcgttgtcagtcagtcaccCAACGACGAGtcacgcagcagcaacagcaacaataaccacaacaataacaacaataataatactaataacaacaacaatacaccTGTAAACCCGACACCCAAACTACCAACGGTagctggagcagcaacaacagctggaggaggaggaggaggaggcggatCAGCAACGTCATCGGGCGGTCGTGATGCACCCAAGTCGCAGTATTTCTCACGCATGCCACAGGTCTGTCCGATCTGTGGCCAGCAGTACAATAACTATAACAATGTGTTGCGCCACATGGAATCGAAGCATCCCAACAAATTGCCCGAGACATACAAGTGTGTGCGTTGTGGACTGGGCTATCCGCGCATCTCCTATCTGCGGGAGCACATGACCAATGTGCATGGTGTGGACAAGAATCGGCAGACGGGCGGATTTGAGTATATTGTGAATGCCGATGCGGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTATACCGGACGATATGATTATGTGATGAAGGATCTTATGTCTATAACAAATGGTGGGACACTCgatgatgatgacgaagaTGGCGGCGACAGCGTCGGCCCCATTCCCAAAAAGATGCGACTTAATGATAGCAGCAGCCTCAACATGAGCAGCATTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTCAGCAACAATATTGGTCTATCGAATCATATGCGTTCCCATTACACAGCATCGATAACGACAAGTGCTGCTCTGGCGGCTGCCAATCGCATGACGCCCAAATCGCTGACAATAACAGCAACGCCACCGCTCGAGacaacaacagcaacaacaactggagtTGTAGCAGTGGCAGCATTTGCTTCTTCCTCATCGGGAGCAGccgcatcaacagcaacaggcacaggaacagcatcaacatcagcatcgtCATCCGGCAAGTTGCCGCCAGCAATGGTGCATCAGACGGCCCAGGAGCAGGCGGTATTCCGTCGCAGTCTGGATCAGGCGGCCGATCGACGATTCCGTCGAATGCGCTGTCGTATCTGCCAGCGGAGATTCAGTTCGAAGAAGTCGTATCGCTACCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTCATAAAGTGCAAGCTGTGTAACGCGGAGTTCGCCTACGAGAAGGGACTGAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCCATCAAGGATGAGATGATTATCAAGCAGTTCGAGTGCGATGTCTGCTCCACTGTTTACAGCTCCGAGCTGGAATTGCAGCAGCATAAGCGCAGCGTACACAAGTCACAAGCCACCACCgattcatcatcatcatcggcagcagcagccggtgGCAAACAATCTTCAAACAAGtcagcgactgcaactgctacCTCCACAGCGGCGGAACTGGCGGCAGACACATCATCCCCGTCGGGCGCGGCAGGGGCGGCCACTCAGCTGCCACTCTACTGGTACCAGTGCAAATATTGTCCATCCAACTTCAACACCAACAAGAAACTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGCCTCTGGgTGCATCGCTACAAGAAGCATCCGCAGGTGCCGGATCCCGCCGAGTGCACGCTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGCAAGCCAATCACTGCCACGGGCGCCCATCAGcaggatcagcagcagcagcagcaacaaccgcaacaacaacagatgcagcagcaatatcaacAGCGAGTCATCTTCAAGCACAAGACGggagatgatgatgacgaggatgaggacgatgaTCAGTTGCAGCTAATGGACGATGGCGGTGGCGGCAGCAATGATAGTAATGCTGGAAATGCcattgcaacagctgcagcagcagcggcgagcACAATAAAGATACGATTTCCGGAGGTGGCATGCACCATTTGCGGTGCCCGGTTCACCGATCAGGAGATGTTTACCAAGCACATACAGAAGCACGAACAGGAACTGTATGTGGACAATCCGTTGGCGGCCATGTTCGATGATGGGCCAGCGGATGCCGGACAATTTCAGATTGAGCACCAGAACGAGAATGGCGAATACGCGTGCGATTTGTGCAACAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGATCCCACTCAACGACGGCGAAGCGACAACGctgaacaacagcagcagcaacaacaacaacaacaacaattcgctGAGCTCATCATCGATGCTGCATCTACGCGAACTGCATGCAGTGGGTCTGATGcccaatcagcagcaacacctgaaacaggaacaacagcagcagcagcaggaacaacagcagcagcagcagcaacaacggacGAGCAAATCAATGAAACGGAAACGTGAACTGAAGTGCGAATACTGCGCCTCCACAttcattagcaacaacaacctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTGCCAGAGCCGCCCGTGATTGAGGTGGATGAGCCTATGACGTGTCGCCGCTGCGGCGATCTGAAGTTTGAGACCAAAGAGGAATGGATCGAGCATAAGCTGGCCGATGCGAGAGTGGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAATATTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGATGTGATTGTGCCGGTCGCCACCaagccaacatcaacaacaccaaataatgttgcaactgcagcagcagcaacagttttaGCTGCCACATCAGCAGTAGGTGCagtagcaaaagcagcagcagaggcggCGAAGGTCAaaacgccaacagcagcaaaggaaCTTAAGTCTAAACAGCAGCTGGACAATGTGAAGCGAACGATACAGCTGGATGGTGTGAAGCAAGcaaagcgacagcagcaagaggaggaggaagaggatgATAGTGATATGGATGATGATAGCGATAGTGgcaatgatgatgaggagggcAGCACCAGTgctgacgacgatgatgaggacgacgatgatgatgaggagggcgacgtcgacgacgatgatgaagatgatgaggAGGGCGACGTCGACGGTGAtgacaaaaatgttattaaactGAAAGTGCTGCGAGAGCTGCCGGAAAatacaaacaccaacaacgacgtcgacgacgatgatgaagatgaaaatgaagatgatgaagatgatgaggagggcgacgacgacgatgatgacaaaaatgttattaaactgaaaatgctgcagcaacagccgaaaaatacaaacaccaacaacgacgtcgacgacgatgatgaagatgaagatgatgaagatgatgaggAGGGCGACGTCGACGGTGATGACAAAAATGTCATTAAACTGAaagtgctgcaacagcagccggaaaatacaaacaccaacaacgacaacaacaacagcgctaTGCTTAATAACATCAATCTCATTGAGCTGGTAATCTTGTCAGAATCCAATgtcgacgacgatgatgaggaagatgacgatgatgacgatgacgacgacgacgatgatgatgatgatgataatgatgacgatgacgatgatggcgaagacgatgacgatgacgatggcgatatcgatgacgatgacgatgataatACAACGGTTGAGCAACTTCAGCCGAGGAGCCTCAATTTCGACTATTCGTGCTCCGACAGCGCCAAGCTAAATGGCAACGGTGGCAAACAGTCTGTGGCGAAATCAAAGAGACTGCCACAGCCAATGCTGGtcatgcacagcagcagcagcagtcgccgcGGAGGTGATGGCGAGGAGGAAGTGGATGAtatggatgatgatgatgatgttgtggGTGAAGCGATGTCCATTGATGATATTATTGTGGAGGATGATGGTGTGGATGATGACGAAGTGGTTGGTGTcggtggtggtgttgttgaggatgatgatgaagatgatgaagaggatgacgatgatggcgatgatgaggatgttggtgcatcatcatcagagagcgagtcgacaacaacaacatcgtaTTCAACTGGAGCTACTTCAGACACACATTAA
Protein Sequence
MCDAATTTTTAAVTTTTAAAQGTGAAGDNAMEEQNQRERKSCCRLCIAPASECISIINSYAADKEPLATKIQNCVNIKITSVDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWQETDKTKQQTLLGYLDLNRAENGNTIEPQQQQQQQQQQQHELKMDSATTAAEKASAANILDGIPQLKKRKSLTVYVSPKQQQQAQQQQSQQHTQQQHATGARSTAKTSTAAAAVAESQPTLQTLLLQVPTAAAAATLATASTQQQQRKHQQQQHHQQQQRGKQPQHQYHQQQQQHRQSRVRQPRRQQQAATAKFRSKLFMPLDISVPALPALLPPPTPAVADAASLLLPLSLPLDFSQNPNLNPNPNQYPNPNQNLNQRYTSSLLVPPPLPLSAPAATMSSNEAAIATGCGATATATAVTTPLLMPPVPAVPIKDEPLYDTDDDFQMRSIDESDDLMDPTMFLERSEHEGDVPLNTSDYDYTAQHGVTAAVAAAALPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAATATAEATRAAAGGNISAQKYRQVVMNTFTKCENGGFDYDNPEQYQQLLSHDKVDFIQKNTEFLEQYQTMTCRCCNKFFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRTKQPNFVHANAASSTATTSTTAAATALNQQQQQMMAANETAAETTTATTTTPTTPTTPTTTPSTPSTDRTEKLRAKDLLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLEHVYQDHLGGVSSDNASQRSLLGSLGIGVVSQSPNDESRSSNSNNNHNNNNNNNTNNNNNTPVNPTPKLPTVAGAATTAGGGGGGGGSATSSGGRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMTNVHGVDKNRQTGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDEDGGDSVGPIPKKMRLNDSSSLNMSSIANQQKECLICNAVFSNNIGLSNHMRSHYTASITTSAALAAANRMTPKSLTITATPPLETTTATTTGVVAVAAFASSSSGAAASTATGTGTASTSASSSGKLPPAMVHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSELELQQHKRSVHKSQATTDSSSSSAAAAGGKQSSNKSATATATSTAAELAADTSSPSGAAGAATQLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQPQQQQMQQQYQQRVIFKHKTGDDDDEDEDDDQLQLMDDGGGGSNDSNAGNAIATAAAAAASTIKIRFPEVACTICGARFTDQEMFTKHIQKHEQELYVDNPLAAMFDDGPADAGQFQIEHQNENGEYACDLCNKTFPQVIALKVHRKWHFRGDSKQIPLNDGEATTLNNSSSNNNNNNNSLSSSSMLHLRELHAVGLMPNQQQHLKQEQQQQQQEQQQQQQQQRTSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPMTCRRCGDLKFETKEEWIEHKLADARVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATKPTSTTPNNVATAAAATVLAATSAVGAVAKAAAEAAKVKTPTAAKELKSKQQLDNVKRTIQLDGVKQAKRQQQEEEEEDDSDMDDDSDSGNDDEEGSTSADDDDEDDDDDEEGDVDDDDEDDEEGDVDGDDKNVIKLKVLRELPENTNTNNDVDDDDEDENEDDEDDEEGDDDDDDKNVIKLKMLQQQPKNTNTNNDVDDDDEDEDDEDDEEGDVDGDDKNVIKLKVLQQQPENTNTNNDNNNSAMLNNINLIELVILSESNVDDDDEEDDDDDDDDDDDDDDDDNDDDDDDGEDDDDDDGDIDDDDDDNTTVEQLQPRSLNFDYSCSDSAKLNGNGGKQSVAKSKRLPQPMLVMHSSSSSRRGGDGEEEVDDMDDDDDVVGEAMSIDDIIVEDDGVDDDEVVGVGGGVVEDDDEDDEEDDDDGDDEDVGASSSESESTTTTSYSTGATSDTH