Dkok015252.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kokeensis
Gene Symbol
hang
Assembly
GCA_035042145.1
Location
JAWNLT010000702.1:7581-23804[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.39 25 5.6 1.0 3 23 509 530 508 530 0.93
2 18 0.64 41 4.9 3.6 3 22 637 656 635 656 0.89
3 18 0.00083 0.053 14.0 3.3 1 22 770 791 770 793 0.90
4 18 0.096 6.2 7.5 0.1 2 21 805 824 804 825 0.93
5 18 0.00096 0.062 13.8 0.2 2 23 957 979 956 979 0.95
6 18 0.0036 0.23 12.0 0.2 1 23 987 1010 987 1010 0.96
7 18 0.00043 0.028 14.9 0.5 2 23 1097 1118 1096 1118 0.97
8 18 0.0004 0.026 15.0 2.9 2 23 1249 1271 1248 1271 0.97
9 18 0.031 2 9.0 0.2 2 23 1280 1302 1279 1302 0.95
10 18 0.0019 0.12 12.8 0.3 1 23 1315 1338 1315 1338 0.97
11 18 0.00017 0.011 16.1 1.1 1 23 1397 1419 1397 1419 0.99
12 18 0.0027 0.17 12.4 0.9 1 23 1427 1450 1427 1450 0.96
13 18 0.094 6 7.5 0.4 2 19 1458 1475 1458 1476 0.94
14 18 0.00016 0.01 16.2 1.4 3 23 1564 1584 1563 1584 0.97
15 18 0.00057 0.037 14.5 0.1 1 23 1619 1641 1619 1641 0.97
16 18 0.0021 0.14 12.7 0.5 2 23 1728 1750 1727 1750 0.92
17 18 0.0089 0.57 10.7 0.3 3 23 1806 1826 1806 1826 0.98
18 18 9.3e-05 0.006 16.9 2.1 1 23 2300 2322 2300 2322 0.99

Sequence Information

Coding Sequence
ATGTGCGAcgctgccacaacaacaacaacagcatcagcagtaacaacaactgcagcgtCAGCACAaggaacaggagcagctgGCGATAATGCGATGGAAGAACAAAATCAGCGAGAGCGACAGAGCTGTTGTCGCCTGTGCATTGCGCCCGCCAGCGAATGCATTTCGATCATCAACAGTTATGCGGCCGATAAGGAGCCGTTGGCcactaaaatacaaaactgcGTAAATATCAAGaTCACATCGGTGGATCGTCTATCGTTGCATATTTGCCATGCCTGCATCAGTTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGTTTCAGCTCACAGTCGAAGCAGCGCCAGTGGCTGGAGACCTACAAAACCAAGCAGCAGACGCTACTCGGATACTTGGATTTGAACAGGGCCGAGAATGGCAACACCATtgaaccacaacaacaacaacagcagcagcagcacgaatTGAAAATGGATTCAGCGACGACGGCAGCTGAAAAGGCGTCCGCTGCCAGCATTTTGGATGGCATACCTCAGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGtccaaagcaacagcagcaagcacagcaacaacagtcgcagcaacatacgcagcaacagcatgcAACAGGGGCAAGATCAACAACGAAAACATcgacggcagcggcggcggtggcggagTCGCAAACAACATTGCAAACCCTTTTATTGCAGGtgcccacagcagcagcagcgacattGGCAACCGCGtcaacacagcaacagcagcgcaagcatcaacagcagcaacaccatcagcagcagcaacgtggcaagcagccgcaacagcagtatcatcaacagcagcagcagcatcgacaGAGTCGCGTTCGTCAACCGCGGCGACAGCAACAAGCGGCAACGGCCAAATTCAGGAGCAAATTGTTTATGCCACTGGATATATCGGTGCCAGCGCTGCCAGCGCTGTTGCCACCGCCGACGccagctgttgctgatgcaacGTCGTTGCTATTGCCGTTGTCGCTGCCACTTGAATTTAGCCAAAATCCGAATCTGAATCCAAATCCCAATCAgtatccaaatccaaatcaaaactTAAATCAGAAATATACAAGTAGCCTTTTAGTGCCGCCCCCGCTGCCGCTGTCCGCGCCAGTTGCAACAATGAGCAGCAACGAGGCTGCCATTGCCACTGGCTGtggtgcaactgcaactgcaaccgcaGTCACGACTCCATTGCTCATGCCGTCGGTGCCTGCCGTGCCCATCAAGGATGAGCCCCTGTACGACACGGATGATGACTTTCAAATGAGGTCCATAGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAAGGCGATGTGCCGCTAAAtACCTCTGACTATGATTATACGGCTCAGCATGGCGTGACCGCGGCTGTGGCGGCGGCATCGCTGCCCGCCAGCGCTGTGGCAAATGTGGCAGCCGCTGGGGACTCGAAGGTAGCCAGCTGCCGGGCGTGCAGTCTGCAGTTCTCGACGCGGGCCAACGCTCGTCGCCACGAGCGCAATCTGCATCCGAATCTGTTTCAATTGTCGACAGACTCACCAAATAATACGCCGATCACAAAACCAACGCCGGCCCTCGCCGCCGCCTTGGAGATACAGCgcgcagcggcggcggcaaccgCAACCGCTGAGGCAACCCGTGCCGCTGCCGGTGGCAATATATCGGCCCAAAAATATCGACAGGTGGTGATGAACACGTTCACCAAATGCGAGAACGGCGGCTTCGACTACGACAATCCCGAACAGTATCAGCAGCTGTTGTCGCATGACAAGGTCGACTTCATCCAGAAGAACACCGAATTTCTCGAACAGTACCAGACGATGACGTGTCGCTGTTGCAACAAGTTCTTCAACACGTACAAGAACTTTATGGCGCACGTTCGCAAAAAGTATCCGTCGCTGCCGCGCAACCTATGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTCAACGCACTGCGCACCAAACAGCCAAACTTTGTCCATGCCAATGCCGCCTCATCCACTGCCACCACATCAACGACAGCTGCGGCGACTGCTctaaaccagcagcagcaacagatggTGACAGCAAacgaaacagcagcagaaacaacaacaccgacagctacaacaccatCAACGGATCGTACGGAGAAGTTGCGTGCCAAGGATCTGCTGGTTAACAAGCTGTACGAGTGCAAGCTGTGCCCAAAGGGTTTCCGCACAAAGCACGAGTTCCGCACCCATGTCTACGATAAGCATGCGGATGTGCAACGCAAAGATAACAATTCGATACAGTGCAGCTTCTGTGGGCTGGACTTTGCCGATCCGGTGGATCGTCGAAGGCATTACAATAACATGGATTGCATTGTGCGGCTGCGCTGCATGACCTGCGATGCCAAACTGGAGACGCATCAGCGCTTCCTCGAACATGTCTATCAGGATCATTTGGGTGGCGTGAGCAGTGATAATGCGTCCCAGCGCAGTTTGCTCGGCTCCCTTGGCATTGGCGTCGCCAGTCAGTCACCCAACGACGAGtcgcgcagcagcaacagcaacaataaccacaacaataacaacaataataatactaataacaacaacaacaacaatccacCAGTAACCCCGACACCCAAACTACCAACGGTAGcgggagcagcaacaacagctggagGAGAAGGAGGTGGATCAGCAACATCATCGGGCGGTCGTGATGCACCCAAGTCGCAGTATTTCTCACGCATGCCACAGGTCTGTCCGATCTGTGGCCAACAGTACAATAACTATAACAATGTGTTGCGCCACATGGAATCGAAGCATCCCAACAAGTTGCCCGAGACATACAAGTGTGTGCGTTGTGGACTGGGCTATCCGCGCATCTCCTATCTGCGGGAGCACATGACCAATGTGCATGGCGTGGACAAGAATCGGCAGACAGGCGGATTTGAGTATATTGTGAATGCCGATGCGGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTATACGGGACGATATGATTATGTGATGAAGGATCTTATGTCTATAACAAATGGTGGGACACTCgatgatgatgacgaagaTGGCGACAGCGTCGGCCCCATTGGCAAAAAGATGCGACTTAATGATAGCAGCAGCCTCAATATGAGCAGCGTTGCCAACCTGCAGAAGAAGTGCCTCCTCTGCAATGCGGTGTTCAGCAACAATATTGGTCTATCGAATCATATGCGTTCCCATTACACACCAATGATGACGCCAAGTGCTGCTCTGGCGGCTGCCAATCGCATGACGCCCAAATCGCTGACAATAACAGCAACGCCGACGTCGCCGTGGCTGTCACCTCGAGCATCATCATCGTTACCGACGGGCACAACAAATACATCAactgtggctgcggctgctgatgcaacaaagacaacaactgTGGCTGGAgttgcagcagtggcagcatttGCTTCTTCCTCATCGGGAGCAGCcgcctcaacaacaacaggcacaggaacagcatcaacatcagcatcatcatccgGCAACTTGCCGCCAGCAATGGCGCACCAGACGGCCCAGGAGCAGGCGGTATTCCGTCGCAGTCTGGATCAGGCGGCCGATCGACGATTCCGTCGAATGCGCTGTCGTATCTGCCAGCGAAGATTCAGTTCGAAGAAGTCGTATCGCTACCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCGGAGTTCGCCTACGAGAAGGGGCTGAAGGTGCATCTGTTCAAGGTGCATGGCCGGGCCATCAAGGATGAGATGATTATCAAGCAGTTCGAGTGCGATGTCTGCTCCACTGTTTACAGCTCCGAGCTGGaattgcagcagcacaagcgcAGCGTACACAAGTCACAAGCCACCACCgattcatcatcatcatcggcagcagcagccggtgGCAAGCAATCGTCAAACAAgtcggcaactgcaactgctactTCCACAGCGGCGGAACTGGCGGCAGACACATCATCTCCGTCGGGCGCGGCAGGGGCGGCCACTCAGCTGCCACTCTACTGGTACCAGTGCAAATATTGTCCATCCAACTTCAACACCAACAAGAAACTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGCCTCTGGgTGCATCGCTACAAGAAGCATCCGCAGGTGCCGGATCCCGCCGAGTGCACGCTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGCAAGCCAATCACTGCCACCGGCGCCCATCAGcaggatcagcagcagcagcagcaacaacaacagatgcagcagcaatatcatCAGCGAGTCATCTTCAAGCACAAAACGggagatgatgatgacgaggatgaggacgatgaTCAGTTGGACGATGGCGGTGGCGGCAGCAATGATAGCAATGTcattgcaacagctgcagcagcagcggcgagcGGCCCAATAAAGATACGCATTCCGGAGGTGGCATGCACCATTTGCGGTGCCCGCTTCACCGATCAGGAGATGTTTACCAAGCACATACATAAGCACGAACAGGAACTGTATGTGGACAATCCGTTGGCGGCCATGTTCGATGATGGGCCAGCGGATGCCGGACAATTTCAGATTGAGCACCAGAACGAGAATGGCGAATACGCGTGCGATTTGTGCAACAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGATCCCACTCAACGACGGCGAAGCGACAACGctgaacaacagcagcaacaacagcagcagcagcaacaacaacaacaacaattcgctGAGCTCATCATCGATGCTGCATCTACGCGAACTGCATGCAGTGGGTCTGATGcccaatcagcagcaacaccagaaacagcagcaggaacaacaacagcagcagcagcagcaacaacggacGAGCAAATCAATGAAACGGAAACGTGAACTGAACTGCGAATACTGCGCCTCCACATtcattagcaacaacaacctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTGCCAGAGCCGCCCGTGATTGAGGTGGATGAGCCGTTGACGTGTCGCCGATGCGGCGATCTGAAGTTTGAGACCAAAGAGCAATGGATCGAGCATAAGCTGGCCGATGCGAGAGTGGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAATATTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGATGTGATTGTGCCGGTTGCCACCaagccaacagcaacgacacccaacaatgttgcaacgggagcagcagctgccacatcaGCTGTaggagcagtagcagaaggagcagcaaAGGCGGCCAAGGTAAAAACGCCAACATCAGCAAAGGAACTGAAGTCTAAACAGCAGCTGGACAATGTGAAGCGAACGATACAGCCGGATGGTGGGAAGCTAacgaagcaacagcagcaagaggaggaggaagaggatgACAGTGATATGGATGATGATAGCGATAGTGGcaatgatgatgaggagggcAGCACCAGTgctgacgacgatgatgaggacGACGATGATGGTGAAGagggcgacgacgacgacgatgatgaagatgatgaggAGAGCGACGTCGACGGTGAtgacaaaaatgttattaaactGAAAATGCTGCAAGAACTGCCGCAAAatacaaacaccaacaacgacgacgacgacgatgatgaagatgatgaggacagcgacgtcgacggtgatgacaaaaatgttattaaactGAAAATGCTGCAAGAACTGCCGCAAAatacaaacaccaacaacgacgacgacgacgatgatgaagatgatgaagatgatgaggacagcgacgtcgacggtgatgacaaaaatgttattaaactGAAAATGCTGAAAGAACTGCCGCAAAatacaaacaccaacaacgacgacgacgacgatgatgaagatgatgaggAGGGCGACGTCGACCGTGAtgacaaaaatgttattaaactGAAAATGCTGAAAGAACTGCCGGAAAATgcaaacaccaacaacgacagcaacaaccgcTCTATACTTAATGACATCGATGTCATTGAGTTGGAAATCTTGTCAGAATGCAATgtcgacgatgatgatgatgataatgatgacgatgatgatgatggcgaagacgatgacgatgacgatgataatACAACGGTTGAGCAACTTCAGCCGAGGGCCCTCAATTTCGACTATTCGTGCACCGGCAGCGCCAAGCTAAATGGCAACGGTGGCGAACAGTCTGTGGCGAAATCAAAGACACAGCCACAGAAAATGATGGTcttgcacagcagcagcggcagtcgCCGCGGGGATGATGGCGAGGAGGAAGTGGATGAtatggatgatgatgatgatgatgatgttgtggGTGAAGCGATGTCCATTGATGATATTATTGTGGAGGATGATGGTGTGGATGATGACGAAGTGGTTGGTGTCGGTGGGGGTGTTgttgaggatgatgatgaagatgatgaagaggatgacgatgatggcgatgatgaGGATGTTGGTACATCATCATCTGAGAGCgaatcgacaacaacaacatcgtaTTCAACTGCGGCACATGGCGCTGCCGCTGATCAGTCTAATTCCATCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCTACTTCAGACACACATTAAAAGTCATTTCCTCAATGGACCATCGGcggggagcagcagcaacaataacaagagcaaTGGCGCCAGCAGGAgcaccaataacaacagcaacaacaacaacaacattagtagtagtagtagcagcaacagcaataacaaaatcaatacCAAAAAGTCCGGCTTGGATGCAACGacgaagacaacaacagcaacaacagttaaaGATGCAGCAACGGACGCTGCAACGGGCTTCAACTGA
Protein Sequence
MCDAATTTTTASAVTTTAASAQGTGAAGDNAMEEQNQRERQSCCRLCIAPASECISIINSYAADKEPLATKIQNCVNIKITSVDRLSLHICHACISYLNSWQSFKNRCFSSQSKQRQWLETYKTKQQTLLGYLDLNRAENGNTIEPQQQQQQQQHELKMDSATTAAEKASAASILDGIPQLKKRKSLTVYVSPKQQQQAQQQQSQQHTQQQHATGARSTTKTSTAAAAVAESQTTLQTLLLQVPTAAAATLATASTQQQQRKHQQQQHHQQQQRGKQPQQQYHQQQQQHRQSRVRQPRRQQQAATAKFRSKLFMPLDISVPALPALLPPPTPAVADATSLLLPLSLPLEFSQNPNLNPNPNQYPNPNQNLNQKYTSSLLVPPPLPLSAPVATMSSNEAAIATGCGATATATAVTTPLLMPSVPAVPIKDEPLYDTDDDFQMRSIDESDDMMDPTMFLERSEHEGDVPLNTSDYDYTAQHGVTAAVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAATATAEATRAAAGGNISAQKYRQVVMNTFTKCENGGFDYDNPEQYQQLLSHDKVDFIQKNTEFLEQYQTMTCRCCNKFFNTYKNFMAHVRKKYPSLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRTKQPNFVHANAASSTATTSTTAAATALNQQQQQMVTANETAAETTTPTATTPSTDRTEKLRAKDLLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLEHVYQDHLGGVSSDNASQRSLLGSLGIGVASQSPNDESRSSNSNNNHNNNNNNNTNNNNNNNPPVTPTPKLPTVAGAATTAGGEGGGSATSSGGRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMTNVHGVDKNRQTGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDEDGDSVGPIGKKMRLNDSSSLNMSSVANLQKKCLLCNAVFSNNIGLSNHMRSHYTPMMTPSAALAAANRMTPKSLTITATPTSPWLSPRASSSLPTGTTNTSTVAAAADATKTTTVAGVAAVAAFASSSSGAAASTTTGTGTASTSASSSGNLPPAMAHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSELELQQHKRSVHKSQATTDSSSSSAAAAGGKQSSNKSATATATSTAAELAADTSSPSGAAGAATQLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQQQMQQQYHQRVIFKHKTGDDDDEDEDDDQLDDGGGGSNDSNVIATAAAAAASGPIKIRIPEVACTICGARFTDQEMFTKHIHKHEQELYVDNPLAAMFDDGPADAGQFQIEHQNENGEYACDLCNKTFPQVIALKVHRKWHFRGDSKQIPLNDGEATTLNNSSNNSSSSNNNNNNSLSSSSMLHLRELHAVGLMPNQQQHQKQQQEQQQQQQQQQRTSKSMKRKRELNCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDLKFETKEQWIEHKLADARVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATKPTATTPNNVATGAAAATSAVGAVAEGAAKAAKVKTPTSAKELKSKQQLDNVKRTIQPDGGKLTKQQQQEEEEEDDSDMDDDSDSGNDDEEGSTSADDDDEDDDDGEEGDDDDDDEDDEESDVDGDDKNVIKLKMLQELPQNTNTNNDDDDDDEDDEDSDVDGDDKNVIKLKMLQELPQNTNTNNDDDDDDEDDEDDEDSDVDGDDKNVIKLKMLKELPQNTNTNNDDDDDDEDDEEGDVDRDDKNVIKLKMLKELPENANTNNDSNNRSILNDIDVIELEILSECNVDDDDDDNDDDDDDGEDDDDDDDNTTVEQLQPRALNFDYSCTGSAKLNGNGGEQSVAKSKTQPQKMMVLHSSSGSRRGDDGEEEVDDMDDDDDDDVVGEAMSIDDIIVEDDGVDDDEVVGVGGGVVEDDDEDDEEDDDDGDDEDVGTSSSESESTTTTSYSTAAHGAAADQSNSIYTCDLCQLCFDSQELLQTHIKSHFLNGPSAGSSSNNNKSNGASRSTNNNSNNNNNISSSSSSNSNNKINTKKSGLDATTKTTTATTVKDAATDAATGFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00496779;
90% Identity
-
80% Identity
-