Basic Information

Insect: Drosophila nigritarsus
Gene Symbol: hang
Assembly: GCA_035044305.1
Location: JAWNMF010000242.1:1193934-1203694[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.37 27 5.6 1.0 3 23 449 470 448 470 0.93

2 18 0.61 45 4.9 3.6 3 22 577 596 575 596 0.89

3 18 0.00079 0.059 14.0 3.3 1 22 723 744 723 746 0.90

4 18 0.091 6.8 7.5 0.1 2 21 758 777 757 778 0.93

5 18 0.00091 0.068 13.8 0.2 2 23 911 933 910 933 0.95

6 18 0.0034 0.25 12.0 0.2 1 23 941 964 941 964 0.96

7 18 0.0002 0.015 15.9 0.2 2 23 1052 1073 1051 1073 0.97

8 18 0.00038 0.028 15.0 2.9 2 23 1214 1236 1213 1236 0.97

9 18 0.03 2.2 9.1 0.2 2 23 1245 1267 1244 1267 0.95

10 18 0.0018 0.13 12.9 0.3 1 23 1280 1303 1280 1303 0.97

11 18 0.00016 0.012 16.2 1.1 1 23 1362 1384 1362 1384 0.99

12 18 0.0025 0.19 12.4 0.9 1 23 1392 1415 1392 1415 0.96

13 18 0.089 6.6 7.6 0.4 2 19 1423 1440 1423 1441 0.94

14 18 3.5e-05 0.0026 18.3 0.4 3 23 1539 1559 1538 1559 0.98

15 18 0.00055 0.041 14.5 0.1 1 23 1594 1616 1594 1616 0.97

16 18 0.0015 0.12 13.1 0.5 2 23 1707 1729 1706 1729 0.92

17 18 0.0084 0.63 10.8 0.3 3 23 1785 1805 1785 1805 0.98

18 18 8.9e-05 0.0066 17.0 2.1 1 23 2207 2229 2207 2229 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.37	27	5.6	1.0	3	23	449	470	448	470	0.93
2	18	0.61	45	4.9	3.6	3	22	577	596	575	596	0.89
3	18	0.00079	0.059	14.0	3.3	1	22	723	744	723	746	0.90
4	18	0.091	6.8	7.5	0.1	2	21	758	777	757	778	0.93
5	18	0.00091	0.068	13.8	0.2	2	23	911	933	910	933	0.95
6	18	0.0034	0.25	12.0	0.2	1	23	941	964	941	964	0.96
7	18	0.0002	0.015	15.9	0.2	2	23	1052	1073	1051	1073	0.97
8	18	0.00038	0.028	15.0	2.9	2	23	1214	1236	1213	1236	0.97
9	18	0.03	2.2	9.1	0.2	2	23	1245	1267	1244	1267	0.95
10	18	0.0018	0.13	12.9	0.3	1	23	1280	1303	1280	1303	0.97
11	18	0.00016	0.012	16.2	1.1	1	23	1362	1384	1362	1384	0.99
12	18	0.0025	0.19	12.4	0.9	1	23	1392	1415	1392	1415	0.96
13	18	0.089	6.6	7.6	0.4	2	19	1423	1440	1423	1441	0.94
14	18	3.5e-05	0.0026	18.3	0.4	3	23	1539	1559	1538	1559	0.98
15	18	0.00055	0.041	14.5	0.1	1	23	1594	1616	1594	1616	0.97
16	18	0.0015	0.12	13.1	0.5	2	23	1707	1729	1706	1729	0.92
17	18	0.0084	0.63	10.8	0.3	3	23	1785	1805	1785	1805	0.98
18	18	8.9e-05	0.0066	17.0	2.1	1	23	2207	2229	2207	2229	0.99

Sequence Information

Coding Sequence: ATGCAACATGCATTTGAATTTCACTATTCCATGTTGatCACATCGGTGGATCGTCTATCGTTGCATATTTGCCATGCCTGCATCAGTTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCACAGTCGAAGCAGCGCCAGTGGCAAGAGACCGACAAAACCAAGCAGCAGACGCTACTCGGATACTTGGATTTGAACAGGGCCGAGAATGGCAACACCATtgaaccacaacaacaacaacagcagcagcagcaccagcaccacgAACTGAAAATGGATTCAGCGACGACTGCAGCTGAAAAGGCGTCCGCTGCCAACATTTTGGATGGCATACCTCAGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGtccaaagcaacagcagcaagcacagcaacaacagtcgcagcaacatacgcagcaacagcatgcAACAGGGGCAAGATCAACAACGAAAACAtcgacggcggcggcggcggtggcggagTCGCAACCAACATTGCAAACCCTTTTATTGCAGGTgcccacagcagcagcagcagcagcgacattGGCAACGGCGtcaacacagcaacagcagcgcaagcatcaacagcagcaacaccatcagcagcagcaacgtggCAAGCAGCCGCAACATCAGtaccatcaacaacagcagcagcatcgacaGAGTCGCGTTCGTCAACCGCGGCGACAGCAACAAGCGGCAACGGCCAAATTCAGGAGCAAATTGTTTATGCCACTGGATATATCGGTGCCAGCGCTGCCAGCGCTGTTGCCACCGCCGACGccagctgttgctgatgcagcGTCGTTGCTATtgccgctgtcgctgccaCTTGATTTTAGCCAGAATCCGAATCTAAATCCAAATCCCAATCAgtatccaaatccaaatcaaaaCTTAAATCAGAGATATACAAGTAGCCTTTTagtgccgccgccgctgccgctgtcCGCGCCAGCTGCAACAATGAGCAGCAACGAGGCTGCCATTGCCACTGGCTgtagtgcaactgcaactgcaactgcaaccgcAGTCACGACTCCATTGCTCATGCCGCCGGTGCCTGCCGTGCCCATCAAGGATGAGCCCCTGTACGACACGGATGATGATTTTCAAATGAGGTCCATAGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAAGGCGATGTGCCACTAAATACCTCTGACTATGATTATACGGCTCAGCATGGCGTGACCGCGGCTGTGGCGGCGGCATCGCTGCCCGCCAGCGCTGTGGCAAATGTGGCAGCCGCTGGGGACTCGAAGGTGGCCAGCTGCCGGGCGTGCAGTCTACAGTTCTCGACGCGGGCCAACGCTCGTCGCCACGAGCGCAATCTGCATCCGAATCTGTTCCAATTGTCGACAGACTCACCAAATAATACGCCGATCACAAAACCAACGCCGGCCCTCGCCGCCGCCTTGGAGATACAGCgtgcagcggcggcggcaaccGCAACCGCTGAGGCAACCCGTGCCGCTGCCGGTGGCAATATATCGGCCCAAAAATATCGACAGGTGGTGATGAACACGTTCACCAAATGCGAGAACGGTGGCTTCGACTACGACAATCCCGAACAGTATCAGCAACTGTTGTCCCACGACAAGGTCGACTTTATCCAAAAGAACACCGAATTTCTCGAACAGTACCAGACGATGACGTGTCGCTGTTGCAACAAGTTCTTCAACACGTACAAGAACTTTATGGCGCACGTGCGCAAAAAGTATCCGTTGCTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTCAACGCACTGCGCACCAAACAGCCAAACTTTGTCCATGCCAATGCCGCCTCATCCACTGCCACCACATCAACGACAGCTGCGGCGACTGCTCtaaaccagcagcagcaacagatggTGGCAGCAAacgaaacagcagcagaaacaacaacagcgacaacaacaacaccaacaacaccaacaacaccaacaacaacaccatcaACACCATCAACGGATCGTACGGAGAAGTTGCGTGCCAAGGATCTACTGGTTAACAAGCTGTACGAGTGCAAGCTGTGCCCAAAGGGTTTCCGCACAAAGCACGAGTTCCGCACCCATGTCTACGATAAGCATGCGGATGTCCAACGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGCCTGGACTTTGCCGATCCGGTGGATCGTCGAAGGCATTACAATAACATGGATTGCATTGTGCGGCTGCGATGCATGACTTGCGATGCCAAACTGGAGACGCATCAGCGCTTCCTCGAACATGTCTATCAGGATCATTTGGGTGGCGTGAGCAGTGATAATGCGTCCCAGCGCAGTTTGCTCGGCTCCCTTGGCATCGGCGTTGTCAGTCAGTCACCCAACGACGAGtcacgcagcagcaacagcaacaataaccacaacaataacaacaataataatactaataacaacaacaacaacaatccacCTGCAACCCCGACACCCAAACTACCAACGGTagctggagcagcaacaacagctggaggaggaggaggatcaGGATCAGCAACATCATCGGGCGGTCGTGATGCACCCAAGTCGCAGTATTTCTCACGCATGCCACAGGTCTGTCCGATCTGTGGCCAGCAGTACAATAACTATAACAATGTGTTGCGCCACATGGAATCGAAGCATCCCAACAAATTGCCCGAGACATACAAGTGTGTGCGTTGTGGACTGGGCTATCCGCGCATCTCCTATCTGCGGGAGCACATGACCAATGTGCATGGTGTGGACAAGAATCGGCAGACGGGCGGATTTGAGTATATTGTGAATGCCGATGCGGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTATACGGGACGATATGATTATGTGATGAAGGATCTTATGTCTATAACAAATGGTGGGACACtcgatgatgatgacgaagaTGGCGGCGACAGCATCGGCCCCATTCCCAAAAAGATGCGACTTAATGATAGCAACAGCCTCAACATGAGCAGTATTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTCAGCAACAATATTGGTCTATCGAATCATATGCGTTCCCATTACACAGCATCGATAACGACAAGTGCTGCTCTGGCGGCTGCCAATCGCATGACGCCCAAATCGCTGACAATAACAGCAACGCCACCGCTCGAGGTGACAGCCACAGCGACGTCGGCGTCGGCAACATCATCGTTAGCGACGGGCACAACAAATACATCATCTGCGGCTGCTTCGGCTGCtgcaacaaagacaacaacagcaacaacaactgtggcTGGAGTTGCAGCAGTGGGAGCATTTGCTTCTTCCTCATCGGGAGCAGCCgcctcaacagcaacaggcacaggaacagcatcaacatcagcatcagcatcatcatccgGCAAGTTGCCGCCAGCAATGGTGCATCAGACGGCCCAGGAGCAGGCGGTATTCCGTCGCAGTCTGGATCAGGCGGCCGATCGACGATTCCGTCGAATGCGCTGTCGTATCTGCCAGCGGAGATTCAGTTCGAAGAAGTCGTATCGCTACCACATGCTTACCGACCATCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCGGAGTTCGCCTACGAGAAGGGACTGAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCCATCAAGGATGAGATGATTATCAAGCAGTTCGAGTGCGATGTCTGCTCCACTGTTTACAGCTCCGAGCTGGaattgcagcagcacaagcgCAGCGTACACAAGTCACAACCCACCACCgattcatcatcatcatcggcagcagcagtcggtGGCAAACAATCATCAAACAAGTCAGCGACTGCAACTGCTACCTCCGCAGCGGCGGAACTGGCGGCAGACACATCATCCCCGTCGGGCGCGGCAGGGGCAGCCACTCAGCTGCCACTCTACTGGTACCAGTGCAAATATTGTCCATCCAACTTCAACACCAACAAGAAACTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGCCTCTGGgTGCATCGCTACAAGAAGCATCCGCAGGTGCCGGATCCCGCCGAGTGCACGCTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGGAAGCCAATCACTGCCACCGGCGCCCATCAGcaggatcagcagcagcagcagcagcagcaacaaccgcaacaacaacagatgcagcagcaatatcaTCAGCGAGTCATCTTCAAGCACAAAACGggagatgatgatgacgaggatgaggacgaTGATCAGTTGCAGCTAATGGACGATGGCGGTGGCGGCAGCAATGATAGCAATGCTGGAAATGCcattgcaacagctgcagcagcagcggcgagcACAATAAAGATACGCTTTCCGGAGGTGGCATGCACCATTTGCGGTGCCCGGTTTACCGATCAGGAGATGTTTACCAAGCACATACAGAAGCACGAACAGGAACTGTATGTGGACGATCCGTTGGCGGCCATGTTCGATGATGGGCCAGCGGATGCCGGACAATTTCAGATTGAGCACCAGAACGAGAATGGCGAATACGCGTGCGATTTGTGCAACAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGATCCCACTCAACGACGGCGAAGCGACAACGctgaacaacagcagcaacaacagcagcagcagcaacaacaacaacaacaattcgctGAGCTCATCATCGATGCTGCATCTACGCGAACTGCATGCAGTGGGTCTGATGCccaatcagcagcaacaccagaaacaggaacaacagcagcagcagcaagaacaacagcagcagcagcagcaacaacggacGAGCAAATCAATGAAACGGAAACGTGAACTGTACTGCGATTACTGCGCCTCCACATtcattagcaacaacaacctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTGCCAGAGCCGCCCGTGATTGAGGTGGATGAGCCGTTGACGTGTCGCCGCTGCGGCGATCTGAAGTTTGAGACCAAAGAGCAATGGATCGAGCATAAGCTGGCCGATGCGAGAGTGGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAATATTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGATGTGATTGTGCCGGTCGCCACCAAGCCAACATCAACGACACCAAATAatgttgcaactgcagcagcagcaacagttttaGCTGTAGGTGcagtagcagaagcagcagctgaggcGGCGAAGGTAAAaacgccaacagcagcaaaggaACTTAAGTCTAAACAGCAGCTGGACAATGTGAAGCGAACGATACAGCTGGATGGTGTGAAGGTAacgaagcaacagcagcaagaggaggaggaagaggatgATAGTGATATGGATGATGATAGCGATAGTGGcaatgatgatgaggaggGCAGCACCAGTgctgacgacgatgatgaggacgacgatgatgatgaggagggcgacgtcgacgacgatgatgaagatgatgaggAGGGCGTCGTCGACGCTGAtgacaaaaatgttattaaactGAAagtgctgcaactgcagccggaaaatacaaacaccaacaacaacgtcgacgacgatgatgaagatgatgaagatgatgaggAGGGCGACGTCGACGATGAtgacaaaaatgttattaaactGAAagtgctgcaacagcagccggaaaatacaaacaccaacaacgacaacaacaacagcgctaTGCTTAATAACATGGATGTCATTGAGTTGGTACTCTTGTCAGAATCCAATgtcgacgacgatgatgaggaagatgacgatgatgacgatgacgacgacgacgatgatgatgatgatgataatgatgacgatgatgatgatggcgaagacgatgacgatgacgatggcgatatcgatgacaatgacaatgacgaTGATAATACAACAGTTGAGCAACTTCGGCCGAGGGCCCTCAATTTCGACTATTCGTGCACCCACAGCGCCAAGCTAAATGGCAATGGTGGCGAACAGTCTGTGGCGAAATCAAagacacagccacagccaatGCTGGTCAtgcacagcagcagtcgcCGCGGGGATGATGGCGAGGAGGAAGTGGATGAtatggatgatgatgatgatgttgtggGTGAAGCGATGTCCATTGATGATATTATTGTGGAGGATGATGGTGTGGATGATGACGAAGTGGTTGGTGTcggtggtggtgttgttgaggatgatgatgaagatgatgaagaggatgacgatgatggCGATGttgCATCAGCGGCACATGGCGCTGCCGCTGATCAATCTAATTCCATCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCTACTTCAGACACATATTAAAAGTCATTTCCTCAATGGGCCATCGGcggggagcagcagcaacagcaacaagagccaTGGCGCCAGCAGGAGCaccaataacagcagcagcaacaacaacaacaacaacagtagtagtagtagtagcagcaacagcaataacaaaatcaatacCAAAAAGTCCGGCTTGGATGCAACGacgaagacaacaacagcaacaacagttaaaGATGCAGCAACGGACGCTGCAACGGGCTTCAATTGA
Protein Sequence: MQHAFEFHYSMLITSVDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWQETDKTKQQTLLGYLDLNRAENGNTIEPQQQQQQQQHQHHELKMDSATTAAEKASAANILDGIPQLKKRKSLTVYVSPKQQQQAQQQQSQQHTQQQHATGARSTTKTSTAAAAVAESQPTLQTLLLQVPTAAAAAATLATASTQQQQRKHQQQQHHQQQQRGKQPQHQYHQQQQQHRQSRVRQPRRQQQAATAKFRSKLFMPLDISVPALPALLPPPTPAVADAASLLLPLSLPLDFSQNPNLNPNPNQYPNPNQNLNQRYTSSLLVPPPLPLSAPAATMSSNEAAIATGCSATATATATAVTTPLLMPPVPAVPIKDEPLYDTDDDFQMRSIDESDDMMDPTMFLERSEHEGDVPLNTSDYDYTAQHGVTAAVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAATATAEATRAAAGGNISAQKYRQVVMNTFTKCENGGFDYDNPEQYQQLLSHDKVDFIQKNTEFLEQYQTMTCRCCNKFFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRTKQPNFVHANAASSTATTSTTAAATALNQQQQQMVAANETAAETTTATTTTPTTPTTPTTTPSTPSTDRTEKLRAKDLLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLEHVYQDHLGGVSSDNASQRSLLGSLGIGVVSQSPNDESRSSNSNNNHNNNNNNNTNNNNNNNPPATPTPKLPTVAGAATTAGGGGGSGSATSSGGRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMTNVHGVDKNRQTGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDEDGGDSIGPIPKKMRLNDSNSLNMSSIANQQKECLICNAVFSNNIGLSNHMRSHYTASITTSAALAAANRMTPKSLTITATPPLEVTATATSASATSSLATGTTNTSSAAASAAATKTTTATTTVAGVAAVGAFASSSSGAAASTATGTGTASTSASASSSGKLPPAMVHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSELELQQHKRSVHKSQPTTDSSSSSAAAVGGKQSSNKSATATATSAAAELAADTSSPSGAAGAATQLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQQQPQQQQMQQQYHQRVIFKHKTGDDDDEDEDDDQLQLMDDGGGGSNDSNAGNAIATAAAAAASTIKIRFPEVACTICGARFTDQEMFTKHIQKHEQELYVDDPLAAMFDDGPADAGQFQIEHQNENGEYACDLCNKTFPQVIALKVHRKWHFRGDSKQIPLNDGEATTLNNSSNNSSSSNNNNNNSLSSSSMLHLRELHAVGLMPNQQQHQKQEQQQQQQEQQQQQQQQRTSKSMKRKRELYCDYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDLKFETKEQWIEHKLADARVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATKPTSTTPNNVATAAAATVLAVGAVAEAAAEAAKVKTPTAAKELKSKQQLDNVKRTIQLDGVKVTKQQQQEEEEEDDSDMDDDSDSGNDDEEGSTSADDDDEDDDDDEEGDVDDDDEDDEEGVVDADDKNVIKLKVLQLQPENTNTNNNVDDDDEDDEDDEEGDVDDDDKNVIKLKVLQQQPENTNTNNDNNNSAMLNNMDVIELVLLSESNVDDDDEEDDDDDDDDDDDDDDDDNDDDDDDGEDDDDDDGDIDDNDNDDDNTTVEQLRPRALNFDYSCTHSAKLNGNGGEQSVAKSKTQPQPMLVMHSSSRRGDDGEEEVDDMDDDDDVVGEAMSIDDIIVEDDGVDDDEVVGVGGGVVEDDDEDDEEDDDDGDVASAAHGAAADQSNSIYTCDLCQLCFDSQELLQTHIKSHFLNGPSAGSSSNSNKSHGASRSTNNSSSNNNNNNSSSSSSSNSNNKINTKKSGLDATTKTTTATTVKDAATDAATGFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496779;
90% Identity: iTF_00496779;
80% Identity: -