Basic Information

Insect: Drosophila seclusa
Gene Symbol: hang
Assembly: GCA_035043575.1
Location: JAWNMX010000522.1:476853-492737[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.37 24 5.6 1.0 3 23 512 533 511 533 0.93

2 17 0.62 40 4.9 3.6 3 22 640 659 638 659 0.89

3 17 0.00081 0.052 14.0 3.3 1 22 781 802 781 804 0.90

4 17 0.093 5.9 7.5 0.1 2 21 816 835 815 836 0.93

5 17 0.00094 0.06 13.8 0.2 2 23 970 992 969 992 0.95

6 17 0.0035 0.22 12.0 0.2 1 23 1000 1023 1000 1023 0.96

7 17 0.00021 0.013 15.9 0.2 2 23 1111 1132 1110 1132 0.97

8 17 0.00039 0.025 15.0 2.9 2 23 1266 1288 1265 1288 0.97

9 17 0.03 1.9 9.1 0.2 2 23 1297 1319 1296 1319 0.95

10 17 0.00086 0.055 13.9 0.3 1 23 1332 1355 1332 1355 0.97

11 17 0.00017 0.011 16.2 1.1 1 23 1414 1436 1414 1436 0.99

12 17 0.0026 0.17 12.4 0.9 1 23 1444 1467 1444 1467 0.96

13 17 0.091 5.8 7.5 0.4 2 19 1475 1492 1475 1493 0.94

14 17 3.5e-05 0.0023 18.3 0.4 3 23 1587 1607 1586 1607 0.98

15 17 0.00056 0.036 14.5 0.1 1 23 1642 1664 1642 1664 0.97

16 17 0.0008 0.051 14.0 0.6 2 23 1754 1776 1753 1776 0.93

17 17 0.0086 0.55 10.8 0.3 3 23 1832 1852 1832 1852 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.37	24	5.6	1.0	3	23	512	533	511	533	0.93
2	17	0.62	40	4.9	3.6	3	22	640	659	638	659	0.89
3	17	0.00081	0.052	14.0	3.3	1	22	781	802	781	804	0.90
4	17	0.093	5.9	7.5	0.1	2	21	816	835	815	836	0.93
5	17	0.00094	0.06	13.8	0.2	2	23	970	992	969	992	0.95
6	17	0.0035	0.22	12.0	0.2	1	23	1000	1023	1000	1023	0.96
7	17	0.00021	0.013	15.9	0.2	2	23	1111	1132	1110	1132	0.97
8	17	0.00039	0.025	15.0	2.9	2	23	1266	1288	1265	1288	0.97
9	17	0.03	1.9	9.1	0.2	2	23	1297	1319	1296	1319	0.95
10	17	0.00086	0.055	13.9	0.3	1	23	1332	1355	1332	1355	0.97
11	17	0.00017	0.011	16.2	1.1	1	23	1414	1436	1414	1436	0.99
12	17	0.0026	0.17	12.4	0.9	1	23	1444	1467	1444	1467	0.96
13	17	0.091	5.8	7.5	0.4	2	19	1475	1492	1475	1493	0.94
14	17	3.5e-05	0.0023	18.3	0.4	3	23	1587	1607	1586	1607	0.98
15	17	0.00056	0.036	14.5	0.1	1	23	1642	1664	1642	1664	0.97
16	17	0.0008	0.051	14.0	0.6	2	23	1754	1776	1753	1776	0.93
17	17	0.0086	0.55	10.8	0.3	3	23	1832	1852	1832	1852	0.98

Sequence Information

Coding Sequence: ATGTGCGAcgctgccacaacaacaacaacagcagcagtaacaacaacaactgcagcagcagcacaaggaACCGGAGCAGCTGGCGATAATGCGATGGAAGAACAAAATCAGCGAGAGCGACAAAGTTGCTGTCGCCTGTGCATTGCGCCCGCCAGCGAATGCATTTCGATCATCAACAGTTATGCGGCCGATAAGGAGCCATTGGCcactaaaatacaaaactgcGTAAATATCAAGATCACATCGGTGGATCGTCTATCGTTGCACATTTGCCATGCCTGCATCAGTTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCACAGTCGAAGCAGCGCCAGTGGCAAGAGACCGACAAAACCAAGCAGCAGACGCTACTCGGATACTTGGATTTGAACAGGGCCGAGAATGGCAACACCATtgaaccacaacaacaacaacagcagcagcagcaccacgaTTTGAAAATGGATTCAGCGACGACTGCAGCTGAAAAGGCGTCCGCTGCCAACATTTTGGATGGCATACCTCAGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGtccaaagcaacagcagcaagcacagcaacaacagtcgcagcaacatacgcagcaacagcatgcAACAGGGGCaagatcaacaacaacgaaaacatcgacggcggcggtggcggagTCGCAACCAACATTGCAAACCCTTTTATTGCAGGtgcccacagcagcagcagcagcgacattGGCAACGGCGtcaacacagcaacagcagcgcaagcatcaacagcagcaacaccatcagcagcatcaacgtggcaagcagccacaacatcagtaccatcaacagcagcagcagcatcgacaGAGTCGCGTTCGTCAACCGCGGCGACAGCAACAAGCGGCAACGGCCAAATTCAGgaacaaattgtttatgcCACTGGATATATCGGTGCCAGCGCTGCCAGCGCTGTTGCCACCGCCGACGccagctgttgctgatgcagcGTCGTTGCTAttgccgctgtcgctgccactTGATTTTAGCCAGAATCCGAATCTAAATCCAAATCCCAATCAGTATCCAAATCCAAACCAAAACTTAAATCAGAGATATACAAGTAGCCTTTTagtgccgccgccgctgccgctgtccGCGCCAGCTGCAACAATGAGCAGCAACGAGGCAGCCATTGCCACTGGCTGTGGTGCAACTgctactgcaactgcaaccgcaGTCACGACTCCATTGCTCATGCCGCCGGTGCCTGCCGTGCCCATCAAGGATGAGCCCCTGTACGACACCGATGATGATTTTCAAATGCGGTCCATAGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCATGAAGGCGATGTGCCACTAAATACCTCTGACTATGATTATACGGCTCAGCATGGCGTGACCGCGGCTGTGGCGGCGGCATCGCTGCCCGCCTGCGCTGTGGCAAATGTGGCAGCCGCTGGCGACTCGAAGGTGGCCAGCTGCCGGGCGTGCAGTCTACAGTTCTCGACGCGGGCCAACGCTCGTCGCCACGAGCGCAATCTGCATCCGAATCTGTTCCAATTGTCGACAGACTCACCAAATAATACGCCGATCACAAAACCAACGCCGGCCCTCGCCGCCGCCTTGGAGATACAGCgcgcagcggcggcggcaaccGCAACCGCTGAGGCAACCCGTGCCGCTGCCGGTGGCAATATATCGGCCCAAAAATATCGACAGGTGGTGATGAACACGTTCACCAAATGCGAGAACGGCGGCTTCGACTACGACAATCCCGAACAGTATCAGCAACTGTTGTCCCACGACAAGGTCGACTTCATCCAAAAGAACACCGAATTTCTCGAACAGTACCAGACGATGACGTGTCGCTGTTGTAACAAGTTCTTCAACACGTACAAGAACTTTATGGCGCACGTGCGCAAAAAGTATCCGTTGCTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTCAACGCACTGCGCACCAAACAGCCAAACTTTGTCCATGCCAATGCCGCCTCATCCACTGCCACCACATCAACGACAGCTGCGGCGACTGCTctaaaccagcagcagcaacagatggTGGCAGCAAacgaaacagcagcagaaacaacaacagcgacaacaacaccaacaacaacaccaacaacaacaccaccatcAACGGATCGTACGGAGAAGTTGCGTGCCAAAGATCTGCTGGTTAACAAGCTGTACGAGTGCAAGCTGTGCCCAAAGGGTTTCCGCACAAAGCACGAGTTCCGCACCCATGTCTACGATAAGCATGCGGATGTGCAACGCAAGGATAATAATTCGATACAGTGTAGCTTCTGTGGCCTGGACTTTGCCGATCCGGTGGATCGTCGAAGGCACTACAATAACATGGATTGCATTGTGCGGCTGCGCTGCATGACTTGCGATGCCAAACTGGAGACGCATCAGCGCTTCCTCGAACATGTCTATCAGGATCATTTGGGTGGCGTGAGCAGTGATAATGCGTCCCAGCGCAGTTTGCTCGGCTCCCTTGGCATCGGcgttgtcagtcagtcaccCAACGACGAGtcgcgcagcagcaacagcaacaataaccacaacaataacaacaataataatactaataacaacaacaacaacaattcatcTGTAACCTCGACACCCAAACTACCAACGGTagctggagcagcaacaacagctggaggaggaggaggaggaggcggatCAGCAACATCATCGGGCGGTCGTGATGCACCCAAGTCGCAGTATTTCTCACGCATGCCACAGGTCTGTCCGATCTGTGGCCAGCAGTACAATAACTATAATAATGTGTTGCGCCACATGGAATCGAAGCATCCCAACAAATTGCCCGAGACATACAAGTGTGTGCGTTGTGGACTGGGCTATCCGCGCATCTCCTATCTACGGGAGCACATGACCAATGTGCATGGCGTGGACAAGAATCGGCAGACGGGCGGATTTGAGTATATTGTGAATGCCGATGCAGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTATACGGGACGATATGATTATGTGATGAAGGATCTTATGTCTATAACAAATGGTGGGACACTcgatgatgatgacgaagaTGGCGGCGACAGCGTCGGCCCCATTGCCAAAAAGATGCGACTTAACGATAGCAGCAGCCTCAACTTGAGCAGCGTTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTCAGCAACAATATTGGTCTATCGAATCATATGCGTTCCCATTACACAGCATCGATAACGACAAGTGCTGCTCTGGCGGCTGCCAATCGCATGACGCCCAAATCGCTGACAATAACAGCAACGCCACCGCTCGAGGTGACAGCcacggcgacgtcgacgtcgtcaaCATCATCGTTAGCGACGGGCACAACAAATACATCAACtgcggctgcttctgctgctgcaacaaagACAACTGTGGCTGGAgttgcagcagtggcagcatttGCTTCTTCCTCATCGGGAGCAGccgcatcaacagcaacaggcacaggaacagcatcaacatcagcatcatcatccgGCAACTTGCCGCCAGCAATGGTGCATCAGACGGCCCAGGAGCAGGCGGTATTCCGTCGCAGTCTGGATCAGGCGGCCGATCGACGATTCCGTCGAATGCGCTGTCGCATCTGCCAGCGAAGATTCAGTTCGAAGAAGTCGTATCGCTACCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCGGAGTTCGCCTACGAGAAGGGACTGAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCCATCAAGGATGAGATGATTATCAAGCAGTTCGAGTGCGATGTCTGCTCCACTGTTTACAGCTCCGAGCTGGAATTGCAGAAGCACAAGCGCAGCGTACACAAGTCACAGGCCACCACCgattcatcatcatcatcggcagcagcagccggtgGCAAACAATCATCAAACAAGtcagcgactgcaactgctACCTCCACAGTGGCGGAACTGGCGGCAGACACCTCATCCCCGTCGGGCGCGGCAGGGGCGGCCACTCAGCTGCCACTCTACTGGTACCAGTGCAAATATTGTCCATCCAACTtcaacaccaacaagaaaCTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGCCTCTGGgTGCATCGCTACAAGAAGCATCCGCAGGTGCCGGATTTCGCCGAGTGCACGCTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGCAAGCCAATCACTGCCACCGGCGCCCATCAACAggatcatcagcagcagcagcagcaacaaccgcaacaacaacagatgcaGCAGCGAGTCATCTTCAAGCACAAAACGggagatgatgatgacgaggatgaggacgatgaTCAGTTGCTAATGGACgatggcggtggcggtggcggcagcaATGATAACAATGCTGGAAATGCcattgcaacagctgcagcagcagcggcgagcACAATAAAGATACGCTTTCCGGAGGTGGCATGCACCATTTGCGGTGCCCGGTTCACCGATCAGGAGATGTTTACCAAGCACATACAGAAGCACGAACAGGAACTGTATGTGGACAATCCGTTGGCGGCCATGTTCGATGATGGGCCAGCGGATGCCGGACAATTTCAGATTGAGCACCAGAACGAGAATGGCGAATACGCGTGCGATTTGTGCAACAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGATCCCACTCAACGACCGCGAAGCGACAACgctgaacaacagcagcaacaacagcagcagcagcaacaacaacaacaattcgctGAGCTCATCATCGATGCTGCATCTACGCGAACTGCATGCAGTGGGTCTGATGCCCAATCAGCAGCGACACCAGAAACAggaacaacagctgcagcagcaggaacaacagcagcagcagcagcaacaacggacGAGCAAATCAATGAAACGGAAACGTGAACTGAAATGCGAATACTGCGCCTCCACAttcattagcaacaacaacttgcgaCGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTGCCAGAGCCGCCCGTGATTGAGGTGGATGAGCCGTTGACGTGTCGCCGCTGCGGCGTTCTGAAGTTTGAGACCAAAGAGCAATGGATCGAGCATAAGCTGGCCGATGCGAGAGTGGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAATATTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGATGTGATTGTGCCGGTCGCCACCAAGCCAACATCAACGACACCAAATaatgttgcaactgcagcagcagcaacagttttaGCTGCCACATCAGCAGTAGGTgcagtagcagaagcagcagcagaggcggCGAAGGTAAaaacgtcaacagcagcaaagggACTTAAGTCTAAACAGCAGCTGGACAACGTGAAGCGAACGATACAGCTGGATGGTGTGAAGCTAacgaagcaacagcagcaagaggaggaggaagagaaTGATAGTGATATGGATGATGATAGCGATAGTGgcaatgatgatgaggagggcAGCACCAGTgctgacgacgatgatgaggacgaCGATCATGATGAGGAgggcgacgtcgacgacgatgatgaagatgatgaggacggcgacgtcgacgatGATGACAGAAATGTTATTAAACTGAAAATGCTGAAACTGCTGCCGgaaaatacaaacacagacagcgacgtcgacgacgatgatgaagatgatgaagatgatgaggagggcgacgacgacgatgatgacagAAATGTTATTAAACTGAAAATGCTGAAACTGCTGCCGGAAAatacaaacaccaacaacgacgtcgacgacgatgatgaagatgatgaagatgatgaggAGGGCGACGTCGACGATAatgacaaaaatattaaactgaaagtgctgcaacagcagccggaaaatacaaacaccaacaacgacaacaacaacagcgcttTACTTAATACTATCAATCTCATTGAGTTGGTACTCTTGGCAGAACCCAATGTCAACGACGGTGATGAGgaagatgacgatgatgacgatgatgatgacgatgatgatgatgatgatgatgatgatgataatgatgataatgataatgataatgatgacgatggcgatgatgatggcgaAGGCgaagacgatgacgatggcgatatcgatgacgatgacgatgataatACAACGGTTAAGCAACTTCAGCCGAGGGCCCTCAATTTCGACTATTCGCGCACCGACAGCGCCAAGCTAAATGGCAACGGTGGCGAACAGTCTGTGGCGAAATCAAAGATACAGCCACAGCCAATGCTGGtcaagcacagcagcagcagcagcagtcgccgcGGGGATGATGGCGAGGAGGAAGTGGATGAtatggatgatgatgatgatgttgtggGTGAAGCGATGTCCATTGATGATATTATTGTGGAGGATGATGGTGTGGATGATGACGAAGTGGTTGGTGTcggtggtggtgttgttgaggatgatgatgatgatgaagaggatgacgatgatggcgatgatgagGATGTTGGTATATCGTCATCTGAGAGCgagtcgacaacaacaacatcgtaTTCAACTGGAGCTACTTCAGACACACATTAA
Protein Sequence: MCDAATTTTTAAVTTTTAAAAQGTGAAGDNAMEEQNQRERQSCCRLCIAPASECISIINSYAADKEPLATKIQNCVNIKITSVDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWQETDKTKQQTLLGYLDLNRAENGNTIEPQQQQQQQQHHDLKMDSATTAAEKASAANILDGIPQLKKRKSLTVYVSPKQQQQAQQQQSQQHTQQQHATGARSTTTKTSTAAVAESQPTLQTLLLQVPTAAAAATLATASTQQQQRKHQQQQHHQQHQRGKQPQHQYHQQQQQHRQSRVRQPRRQQQAATAKFRNKLFMPLDISVPALPALLPPPTPAVADAASLLLPLSLPLDFSQNPNLNPNPNQYPNPNQNLNQRYTSSLLVPPPLPLSAPAATMSSNEAAIATGCGATATATATAVTTPLLMPPVPAVPIKDEPLYDTDDDFQMRSIDESDDMMDPTMFLERSEHEGDVPLNTSDYDYTAQHGVTAAVAAASLPACAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAATATAEATRAAAGGNISAQKYRQVVMNTFTKCENGGFDYDNPEQYQQLLSHDKVDFIQKNTEFLEQYQTMTCRCCNKFFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRTKQPNFVHANAASSTATTSTTAAATALNQQQQQMVAANETAAETTTATTTPTTTPTTTPPSTDRTEKLRAKDLLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLEHVYQDHLGGVSSDNASQRSLLGSLGIGVVSQSPNDESRSSNSNNNHNNNNNNNTNNNNNNNSSVTSTPKLPTVAGAATTAGGGGGGGGSATSSGGRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMTNVHGVDKNRQTGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDEDGGDSVGPIAKKMRLNDSSSLNLSSVANQQKECLICNAVFSNNIGLSNHMRSHYTASITTSAALAAANRMTPKSLTITATPPLEVTATATSTSSTSSLATGTTNTSTAAASAAATKTTVAGVAAVAAFASSSSGAAASTATGTGTASTSASSSGNLPPAMVHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSELELQKHKRSVHKSQATTDSSSSSAAAAGGKQSSNKSATATATSTVAELAADTSSPSGAAGAATQLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDFAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDHQQQQQQQPQQQQMQQRVIFKHKTGDDDDEDEDDDQLLMDDGGGGGGSNDNNAGNAIATAAAAAASTIKIRFPEVACTICGARFTDQEMFTKHIQKHEQELYVDNPLAAMFDDGPADAGQFQIEHQNENGEYACDLCNKTFPQVIALKVHRKWHFRGDSKQIPLNDREATTLNNSSNNSSSSNNNNNSLSSSSMLHLRELHAVGLMPNQQRHQKQEQQLQQQEQQQQQQQQRTSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGVLKFETKEQWIEHKLADARVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATKPTSTTPNNVATAAAATVLAATSAVGAVAEAAAEAAKVKTSTAAKGLKSKQQLDNVKRTIQLDGVKLTKQQQQEEEEENDSDMDDDSDSGNDDEEGSTSADDDDEDDDHDEEGDVDDDDEDDEDGDVDDDDRNVIKLKMLKLLPENTNTDSDVDDDDEDDEDDEEGDDDDDDRNVIKLKMLKLLPENTNTNNDVDDDDEDDEDDEEGDVDDNDKNIKLKVLQQQPENTNTNNDNNNSALLNTINLIELVLLAEPNVNDGDEEDDDDDDDDDDDDDDDDDDDNDDNDNDNDDDGDDDGEGEDDDDGDIDDDDDDNTTVKQLQPRALNFDYSRTDSAKLNGNGGEQSVAKSKIQPQPMLVKHSSSSSSRRGDDGEEEVDDMDDDDDVVGEAMSIDDIIVEDDGVDDDEVVGVGGGVVEDDDDDEEDDDDGDDEDVGISSSESESTTTTSYSTGATSDTH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496779;
90% Identity: iTF_00496779;
80% Identity: -