Dtri006472.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila trichaetosa
Gene Symbol
hang
Assembly
GCA_035043205.1
Location
JAWNNE010000148.1:274015-290182[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.37 25 5.6 1.0 3 23 513 534 512 534 0.93
2 17 0.62 41 4.9 3.6 3 22 641 660 639 660 0.89
3 17 0.0008 0.053 14.0 3.3 1 22 785 806 785 808 0.90
4 17 0.092 6.1 7.5 0.1 2 21 820 839 819 840 0.93
5 17 0.00093 0.062 13.8 0.2 2 23 974 996 973 996 0.95
6 17 0.0035 0.23 12.0 0.2 1 23 1004 1027 1004 1027 0.96
7 17 0.0002 0.014 15.9 0.2 2 23 1115 1136 1114 1136 0.97
8 17 0.00038 0.025 15.0 2.9 2 23 1243 1265 1242 1265 0.97
9 17 0.03 2 9.0 0.2 2 23 1274 1296 1273 1296 0.95
10 17 0.0018 0.12 12.9 0.3 1 23 1309 1332 1309 1332 0.97
11 17 0.00017 0.011 16.1 1.1 1 23 1391 1413 1391 1413 0.99
12 17 0.0026 0.17 12.4 0.9 1 23 1421 1444 1421 1444 0.96
13 17 0.091 6 7.5 0.4 2 19 1452 1469 1452 1470 0.94
14 17 3.5e-05 0.0023 18.3 0.4 3 23 1564 1584 1563 1584 0.98
15 17 0.00056 0.037 14.5 0.1 1 23 1619 1641 1619 1641 0.97
16 17 0.00079 0.053 14.0 0.6 2 23 1731 1753 1730 1753 0.93
17 17 0.0086 0.57 10.7 0.3 3 23 1809 1829 1809 1829 0.98

Sequence Information

Coding Sequence
ATGTGCGAcgctgccacaacaacaacaactacagcagcagcagtaacaacaacaactgcagcagcagcagcacaaggaacaggagcagctgGCGATAATGCGATGGAAGAACAAAATCAGCGAGAGCGACAAAGCTGCTGTCGCCTGTGCATTGCGCCCGCCAGCGAATGCATTTCGATCATCAACAGTTATGCGGCCGATAAGGAGCCGTTGGCtactaaaatacaaaactgcGTAAATATCAAGATCACATCGGTGGATCGTCTATCGTTGCATATTTGCCATGCCTGCATCAGTTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCCTTAGCTCACAGTCGAAGCAGCGCCAGTGGCAAGAGACCGACAAAACCAAGCAGCAGACGCTACTCGGATACTTGGATTTGAACAGGGCCGAGAATGGCAACACCATtgaaccacaacaacaacaacaacaacagcagcacgaaTTGAAATTGGATTCAGCGACGACTGCAGCTGAAAAGGCGTCCGCTGCCAACATTTTGGATGGCATACCTCAGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGtccaaagcaacagcagcaagcacagcaacaacagtcgcagcaacatacgcagcaacagcatgcaACAGGGGCAAGATCAACAACGAAAACAtcgacggcggcggcggcggtggcggagTCGCAACCAACATTGCAAACCCTTTTATTGCAGGtgcccacagcagcagcagcagcgacattGGCAACGGCgtcaacacagcaacagcagcgcaagcatcaacagcagcaacaccatcagcagcagcaacgtggcAAGCAGCCGCAACATCAGtaccatcaacagcagcagcagcatcgacaGAGTCGCGTTCGTCAACCGCGGCGACAGCAACAATCGGCAACGGCCAAATTCAGGAGCAAATTGTTTATGCCACTGGATATATCGGTGCCAGCGCTGCCAGCGCTGTTGCCACCGCCGACGccagctgttgctgatgcagcGTCGTTGCTATTGCCGCTGTCGCTACCACTTGATTTTAGCCAGAATCCGAATCTAAATCCAAATCCCAATCAgtatccaaatccaaatcaaaactTAAGTCAGAGATATACAAGTAGCCTTTTagtgccgccgccgctgccgctgtccGCGCCAGCTGCAACAATGAGCAGCAACGAGGCTGCCATTGCCACTGGCTGtggtgcaactgcaactgcaaccgcaGTCACGACTCCATTGCTCATGCCGCCGGTGCCTGCCGTGCCCATCAAGGATGAGCCCCTGTACGACACGGATGATGAATTTCTAATGAGGTCCATAGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGATCACGAAGGCGATGTGCCACtaaatACCTCTGACTATGATTATACGGCTCAGCATGGCGTGACCGCGGCTGTGGCGGCGGCATCGCTGCCCGCCAGCGCTGTGGCAAATGTGGCAGCCGCTGGAGACTCGAAGGTGGCCAGCTGCCGGGCGTGCAGTCTACAGTTCTCGACGCGGGCCAACGCTCGACGCCACGAGCGCAATCTGCATCCGAATCTGTTCCAATTGTCGACAGACTCACCAAATAATACGCCGATCACAAAACCAACGCCGGCCCTCGCCGCCGCCTTGGAGATACAGCgcgcagcggcggcggcaaccgCAACCGCTGAGGCAACCCGTGCCGCTGCCGGTGGCAATATATCGGCCCAAAAATATCGACAGGTGGTGATGAACACGTTCACCAAATGCGAGAACGGTGGCTTCGACTACGACAATCCCGAACAGTATCAGCAACTGTTGTCCCACGACAAGGTCGACTTCATCCAAAAGAACACCGAATTTCTCGAACAGTACCAGACGATGACGTGTCGCTGTTGCAACAAGTTCTTCAACACGTACAAGAACTTTATGGCGCACGTGCGCAAAAAGTATCCGTTGCTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTCAACGCACTGCGCACCAAACAGCCAAACTTTGTCCATGCCAATGCCGCCTCATCCACTGCCACCACATCAACGACAGCTGCGGCGACTGCTctaaaccagcagcagcaacagatggTGGCAGCAAacgaaacagcagcagaaacaacaacagcgacaacaacaacaccaacaacaccaacaacaacaacaccatcaaCACCATCAACGGATCGTACGGAGAAGTTGCGTGCCAAGGATCTGCTGGTTAACAAGCTGTACGAGTGCAAACTGTGCCCAAAGGGTTTCCGCACAAAGCACGAGTTCCGCACCCATGTCTACGATAAGCATGCGGATGTTCAACGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGCCTGGACTTTGCCGATCCGGTGGATCGTCGAAGGCATTACAATAACATGGATTGCATTGTGCGGCTGCGCTGCATGACTTGCGATGCCAAACTGGAGACGCATCAGCGCTTCCTCGAACATGTCTATCAGGATCATTTGGGTGGCGTGAGCAGTGATAATGCGTCCCAGCGCAGTTTGCTCGGCTCCCTTGGCATCGGcgttgtcagtcagtcaccCAACGACGAGtcacgcagcagcaacagcaacaataaccacaacaataacaacaacaataatactaataacaacaacaacaacaatccacTTGTAACCCCGACACCAAAACTACCAACGGTagctggagcagcaacaacagctggaggcggaggaggaggaggcggatCAGCAACATCATCGGGCGGTCGTGATGCACCCAAGTCGCAGTATTTCTCACGCATGCCACAGGTCTGTCCGATCTGTGGCCAGCAGtacaataactacaacaatgtGTTGCGCCACATGGAATCGAAGCATCCCAACAAATTGCCCGAGACATACAAGTGTGTGCGTTGTGGACTGGGCTATCCGCGCATCTCCTATCTGCGGGAGCACATGACCAATGTGCATGGCGTGGACAAGAATCGGCAGACGGGCGGATTTGAGTATATTGTGAATGCCGATGCGGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTATACGGGACGATATGATTATGTGATGAAGGATCTTATGTCTATAACAAATGGTGGGACACTcgATGATGACGACGAAGATGGCGGCGACAGCGTCGGCCCCATTCCCAAAAAGATGCGACTTAATGATAGCAGCAGCCTCAACATGAGCAGCATTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTCAGCAACAATATTGGTCTATCGAATCATATGCGTTCCCATTACACAGCATCGATAACGACAAGTGCTGCTCTGGCGGCTGCCAATCGCATGACGCCCAAATCGCTGACAATAACAGCAACGCCACCACTCGAGacaacagcagcaacaacaactgtggcTGGAgttgcagcagtggcagcatttGCTTCTTCCTCATCGGGAGCAGCCgcctcaacagcaacaggcacaggaacagcatcaacatcagcatcatcatccgGCAAGTTGCCGCCAGCAATGGTGCATCAGACGGCCCAGGAGCAGGCGGTATTCCGTCGCAGTCTGGATCAGGCGGCCGATCGACGATTCCGTCGAATGCGCTGTCGTATCTGCCAGCGGAGATTCAGTTCGAAGAAGTCGTATCGCTACCACATGCTTACCGACCATCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCGGAGTTCGCCTACGAGAAGGGACTGAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCCATCAAGGATGAGATGATTATCAAGCAGTTCGAGTGCGATGTCTGCTCCACTGTTTACAGCTCCGAGCTGGaattgcagcagcacaagcgCAGCGTACACAAGTCACAAGCCACCACCgattcatcatcatcatcggcagcagcagccggtgGCAAACAATCATCAAACAAGTCAGCGGCTGCAACTGCTACCTCCACAGCGGCGGAACTGGCGGCAGACACATCATCCCAGTCGGGCGCGGCAGGGGCGGCCACTCAGCTGCCACTCTACTGGTACCAGTGCAAATATTGTCCATCCAACTTCAACACCAACAAGAAACTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGCCTCTGGgTGCATCGCTACAAGAAGCATCCGCAGGTGCCGGATCCCGCCGAGTGCACGCTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGCAAGCCAATCACTGCCACCGGCGCCCATCAGcaggatcagcagcagcaacaaccgcaacaacaacagatgcagcagcaatatcaacAGCGAGTCATCTTTAAGCACAAAACGggagatgatgatgacgaggatgacgacgatgatcaGTTGCAGCTAATGGACGATGGCGGTGGCGGCAGCAATGATAGCAATGCTGGAAATGTcattgcaacagctgcagcagcagcggcaagcaCAATAAAGATACGCTTTCCGGAGGTGGCATGCACCATTTGCGGTGCCCGGTTCACCGATCAGGAGATGTTTACCAAGCACATACAGAAGCACGAACAGGAACTGTATGTGGACAATCCGTTGGCGGCCATGTTCGATGATGGGCCAGCGGATGCCGGACAATTTCAGATTGAGCACCAGAACGAGAATGGCGAATACGCGTGCGATTTGTGCAACAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGATCCCACTCAACGACGGCGAAGCGACAACgctgaacaacagcagcaacaacagcagcagcagcaacaacaacaacaattcgctGAGCTCATCATCGATGCTGCATCTACGCGAACTGCATGCTGTGGGTCTGATGcccaatcagcagcaacaccagaaacagcaacaacagcagcagcagcaggaacaacagcagcagcagcagcaacaacggacAAGCAAATCAATGAAACGGAAACGTGAACTGAAGTGCGAATACTGCGCCTCCACAttcattagcaacaacaacctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTGCCAGAGCCGCCCGTGATTGAGGTGGATGAGCCGTTGACGTGTCGCCGCTGCGGCAATCTGAAGTTTGATACCAAAGAGCAATGGATCGAGCATAAGCTGGCCGATGCGAGAGTGGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAATATTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGATGTGATTGTGCCGGTCGCCACCAAACCAACATCAACGACACCAAATAATgttgcaacggcagcagcagcaacagttttaGCTGCCACATCAGCAGTAGGTgcagtagcagaagcagcagcagaggcggCGAAGGCAAaaacgccaacagcagcaaaggaACTTAAGTCTAAACAGCAGCTGGACAATGTGAAGCGAACGATACAGCTGGATGGTGAGAAGCTAacgaagcaacagcagcaagaggaggaggaagaggatgATAGTGATATGGATGATGATAGCGATAGTGgcaatgatgatgaggagggcAGCACCAGTgctgacgacgatgatgaggacgacgatgatgatgaggagggcgacgtcgacgacgatgatgaagatgatgaggAGGGCGACGTCGACAATGAtcacaaaaatgttattaaactGAAAGTGCTGAGACAACAGCCGGAAAatacaaacaccaacaacgacgtcgacgacgatgatgaagatgatgaagatgatgaagatgatgaggAGGGCGACGTCGACGATGAtgacaaaaatgttattaaactGAAAGTGCTGCGACGACAGCCGGAAAatacaaacaccaacaacgacgtcgacgacgatgatgaagatgatgaagatgatgaggAGGGCGACGTCGACGATGAtgacaaaaatgttattaaactGAAAATGCTGCGACAACAGCCGGAAAatacaaacaccaacaacaacagcaacagcgctATGCATAATAACATCGATCTCATTGAGTTGGTAATCTTGTCAGAATCCAATgttgacgacgatgatgaggaagatgacgatgatgacgatgatgacgacgacgacgatgatgatgatgacgatgatgataatgatgacgatgatgatgatggcgaagacgatgacgatggcgataTCGATGGCGAtatcgatgacgatgacaatgaTAATACAACGGTTGAGCAACATCAGCCGAGGGCCCTCAATTTCGACTATTCGTGCACCGACAGCGCCAAGCTAAATGGCAACGGTGGCGAACAGTCTGTGGCGAAATCAAagacacagccacagccaatgCTGGtaatgcacagcagcagcagcagcagtcgccgcGGGGATGATGGCGAGGAGGAAGTGGATGAtatggatgatgatgatgatgttgtggGTGAAGCGATGTCCATTGATGATATTATTGTGGAGGATGATGGTGTGGATGATGACGAAGTGGTTGGTGTcggtggtggtgttgttgaggatgatgatgaagatgatgaagaggatgacgatgatggcgatgatgaGGATGAGCTACTTCAGACACACATTAAAAGTCATTTCCTCAATGGGCCATCGGcggggagcagcagcaacagcaacaagagcaatgGCGCCAGCAGGAGCaccaataacagcagcagcaacaacaacagtagtagtagtagcagtagcagcaacagcaataacaaaatcaatacCAAAAAGTCCGGCTTGGATGCACCGacgaagacaacaacagcaacaacagttaaaGATGCAGCAACGGACGCTGCAACGGGCTTCAACTGA
Protein Sequence
MCDAATTTTTTAAAVTTTTAAAAAQGTGAAGDNAMEEQNQRERQSCCRLCIAPASECISIINSYAADKEPLATKIQNCVNIKITSVDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWQETDKTKQQTLLGYLDLNRAENGNTIEPQQQQQQQQHELKLDSATTAAEKASAANILDGIPQLKKRKSLTVYVSPKQQQQAQQQQSQQHTQQQHATGARSTTKTSTAAAAVAESQPTLQTLLLQVPTAAAAATLATASTQQQQRKHQQQQHHQQQQRGKQPQHQYHQQQQQHRQSRVRQPRRQQQSATAKFRSKLFMPLDISVPALPALLPPPTPAVADAASLLLPLSLPLDFSQNPNLNPNPNQYPNPNQNLSQRYTSSLLVPPPLPLSAPAATMSSNEAAIATGCGATATATAVTTPLLMPPVPAVPIKDEPLYDTDDEFLMRSIDESDDMMDPTMFLERSDHEGDVPLNTSDYDYTAQHGVTAAVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAATATAEATRAAAGGNISAQKYRQVVMNTFTKCENGGFDYDNPEQYQQLLSHDKVDFIQKNTEFLEQYQTMTCRCCNKFFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRTKQPNFVHANAASSTATTSTTAAATALNQQQQQMVAANETAAETTTATTTTPTTPTTTTPSTPSTDRTEKLRAKDLLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLEHVYQDHLGGVSSDNASQRSLLGSLGIGVVSQSPNDESRSSNSNNNHNNNNNNNTNNNNNNNPLVTPTPKLPTVAGAATTAGGGGGGGGSATSSGGRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMTNVHGVDKNRQTGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDEDGGDSVGPIPKKMRLNDSSSLNMSSIANQQKECLICNAVFSNNIGLSNHMRSHYTASITTSAALAAANRMTPKSLTITATPPLETTAATTTVAGVAAVAAFASSSSGAAASTATGTGTASTSASSSGKLPPAMVHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSELELQQHKRSVHKSQATTDSSSSSAAAAGGKQSSNKSAAATATSTAAELAADTSSQSGAAGAATQLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQPQQQQMQQQYQQRVIFKHKTGDDDDEDDDDDQLQLMDDGGGGSNDSNAGNVIATAAAAAASTIKIRFPEVACTICGARFTDQEMFTKHIQKHEQELYVDNPLAAMFDDGPADAGQFQIEHQNENGEYACDLCNKTFPQVIALKVHRKWHFRGDSKQIPLNDGEATTLNNSSNNSSSSNNNNNSLSSSSMLHLRELHAVGLMPNQQQHQKQQQQQQQQEQQQQQQQQRTSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGNLKFDTKEQWIEHKLADARVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATKPTSTTPNNVATAAAATVLAATSAVGAVAEAAAEAAKAKTPTAAKELKSKQQLDNVKRTIQLDGEKLTKQQQQEEEEEDDSDMDDDSDSGNDDEEGSTSADDDDEDDDDDEEGDVDDDDEDDEEGDVDNDHKNVIKLKVLRQQPENTNTNNDVDDDDEDDEDDEDDEEGDVDDDDKNVIKLKVLRRQPENTNTNNDVDDDDEDDEDDEEGDVDDDDKNVIKLKMLRQQPENTNTNNNSNSAMHNNIDLIELVILSESNVDDDDEEDDDDDDDDDDDDDDDDDDDNDDDDDDGEDDDDGDIDGDIDDDDNDNTTVEQHQPRALNFDYSCTDSAKLNGNGGEQSVAKSKTQPQPMLVMHSSSSSSRRGDDGEEEVDDMDDDDDVVGEAMSIDDIIVEDDGVDDDEVVGVGGGVVEDDDEDDEEDDDDGDDEDELLQTHIKSHFLNGPSAGSSSNSNKSNGASRSTNNSSSNNNSSSSSSSSNSNNKINTKKSGLDAPTKTTTATTVKDAATDAATGFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00496779;
90% Identity
iTF_00496779;
80% Identity
-