Basic Information

Insect: Drosophila neutralis
Gene Symbol: hang
Assembly: GCA_035044385.1
Location: JAWNME010000315.1:7074353-7090200[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.4 27 5.6 1.0 3 23 519 540 518 540 0.93

2 17 0.66 45 4.9 3.6 3 22 647 666 645 666 0.89

3 17 0.00085 0.058 14.0 3.3 1 22 790 811 790 813 0.90

4 17 0.098 6.7 7.5 0.1 2 21 825 844 824 845 0.93

5 17 0.00099 0.067 13.8 0.2 2 23 979 1001 978 1001 0.95

6 17 0.0037 0.25 12.0 0.2 1 23 1009 1032 1009 1032 0.96

7 17 0.00022 0.015 15.9 0.2 2 23 1120 1141 1119 1141 0.97

8 17 0.00041 0.028 15.0 2.9 2 23 1280 1302 1279 1302 0.97

9 17 0.032 2.2 9.0 0.2 2 23 1311 1333 1310 1333 0.95

10 17 0.0019 0.13 12.9 0.3 1 23 1346 1369 1346 1369 0.97

11 17 0.00018 0.012 16.1 1.1 1 23 1428 1450 1428 1450 0.99

12 17 0.0028 0.19 12.4 0.9 1 23 1458 1481 1458 1481 0.96

13 17 0.097 6.6 7.5 0.4 2 19 1489 1506 1489 1507 0.94

14 17 3.8e-05 0.0026 18.3 0.4 3 23 1601 1621 1600 1621 0.98

15 17 0.00059 0.04 14.5 0.1 1 23 1656 1678 1656 1678 0.97

16 17 0.00084 0.057 14.0 0.6 2 23 1763 1785 1762 1785 0.93

17 17 0.0091 0.62 10.7 0.3 3 23 1841 1861 1841 1861 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.4	27	5.6	1.0	3	23	519	540	518	540	0.93
2	17	0.66	45	4.9	3.6	3	22	647	666	645	666	0.89
3	17	0.00085	0.058	14.0	3.3	1	22	790	811	790	813	0.90
4	17	0.098	6.7	7.5	0.1	2	21	825	844	824	845	0.93
5	17	0.00099	0.067	13.8	0.2	2	23	979	1001	978	1001	0.95
6	17	0.0037	0.25	12.0	0.2	1	23	1009	1032	1009	1032	0.96
7	17	0.00022	0.015	15.9	0.2	2	23	1120	1141	1119	1141	0.97
8	17	0.00041	0.028	15.0	2.9	2	23	1280	1302	1279	1302	0.97
9	17	0.032	2.2	9.0	0.2	2	23	1311	1333	1310	1333	0.95
10	17	0.0019	0.13	12.9	0.3	1	23	1346	1369	1346	1369	0.97
11	17	0.00018	0.012	16.1	1.1	1	23	1428	1450	1428	1450	0.99
12	17	0.0028	0.19	12.4	0.9	1	23	1458	1481	1458	1481	0.96
13	17	0.097	6.6	7.5	0.4	2	19	1489	1506	1489	1507	0.94
14	17	3.8e-05	0.0026	18.3	0.4	3	23	1601	1621	1600	1621	0.98
15	17	0.00059	0.04	14.5	0.1	1	23	1656	1678	1656	1678	0.97
16	17	0.00084	0.057	14.0	0.6	2	23	1763	1785	1762	1785	0.93
17	17	0.0091	0.62	10.7	0.3	3	23	1841	1861	1841	1861	0.98

Sequence Information

Coding Sequence: ATGTGCGAcgctgccacaacaacaacaccaacaacaacagcagcagcagcagtaacagcaacaactgcagcagcagcacaaggaACAGGAGCAGCTGGCGACAATGCGATGGAAGAACAAAATCAGCGAGAGCGACAAAGCTGCTGTCGCCTGTGCATTGCGCCCGCCAGCGAATGCATTTCGATCATCAACAGTTATGCGGCCGATAAGGAGCCGTTggccacaaaaatacaaaactgcGTAAATATCAAGATCACATCGGTGGATCGTCTATCGTTGCATATTTGCCATGCCTGCATCAGTTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCACAGTCGAAGCAGCGCCAGTGGCAAGAGACCGACAAAACCAAGCAGCAGACGCTACTCGGATACTTGGATTTGAACAGGGCCGAGAATGGCAACACCATtgaaccacaacaacaacaacaacaacagcagcagcagcacgaatCGAAAATGGATTCAGCGACGACCGCAGCTGAAAAGGCGTCCGCTGCCAACATTTTGGATGGCATACCTCAGTTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGtccaaagcaacagcagcaagcacagcaacaacagtcgcagcaacatacgcagcaacagcatgcAACAGGGGCAAGatcaacaacgaaaacatcgacggcggcggcggcggtggcggagTCTCAACCAACATTGCAAACCCTTTTATTGCAGGtgcccacagcagcagcagcagcgacattgGCAACGGCGtcaacacagcaacagcagcgcaagcatcaacagcagcaacaccatcagcagcagcaacgtggCAAGCAGCCGCAACATCAGTaccatcaacagcagcagcagcatcgacaGAGTCGCGTTCGTCAACCGCGGCGACAGCAACAAGCGGCAACGGCCAAATTCAGGAGCAAATTGTTTATGCCACTGGATATATCGGTGCCAGCGCTGCCAGCACTGTTGCCACCGCCGACGccagctgttgctgatgcagcGTCGTTGCTAttgccgctgtcgctgccactTGATTTTAGCCAGAATCCGAATCTAAATCCAAATCCCAATCAgtatccaaatccaaatcaaaaCTTAAATCAGAGATATACGAGTAGCCTTTTagtgccgccgccgctgccgctgtccGCGCCAGCTGCAACAATGAGCAGCAACGAGGCTGCCATTGCCACTGGCTGtggtgcaactgcaactgcaactgcaaccgcaGTCACGACTCCATTGCTCATGCCGCCGGTGCCTGCCGTGCCCATCAAGGATGAGCCCCTGTACGACACGGATGATGATTTTCAAATGAGGTCCATAGACGAATCCGATGATTTGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAAGGCGATGTGCCACTaaatACCTCTGACTATGATTATACGGCTCAGCATGGAGTGACCGCGGCTGTGGCGGCGGCATCACTGCCCGCCTGCGCTGTGGCAAATGTGGCAGCCGCTGGGGACTCGAAGGTGGCCAGCTGCCGGGCATGCAGTCTACAGTTCTCGACGCGGGCCAACGCTCGTCGCCACGAGCGCAATCTGCATCCGAATCTGTTCCAATTGTCGACAGACTCACCAAATAATACGCCGATCACAAAACCAACGCCGGCCCTCGCCGCCGCCTTGGAGATACAGCgcgcagcagcggcggcaaccGCAACCGCTGAGGCAACCCGTGCCGCTGCCGGTGGCAATATATCGGCCCAAAAATATCGACAGGTGGTGATGAACACGTTCACCAAATGCGAGAACGGTGGCTTCGACTACGACAATCCCGAACAGTATCAGCAACTGTTGTCCCACGACAAGGTCGACTTCATCCAAAAGAACTCCGAATTTCTCGAACAGTACCAGACGATGAcgtgtcgctgttgcaacaAGTTCTTCAACACGTACAAGAACTTTATGGCGCACGTGCGCAAAAAGTATCCGTTGCTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTCAACGCACTGCGCACCAAACAGCCAAACTTTGTCCATGCCAATGCCGCCTCATCCACTGCCACCACATCAGCGACAGCTGCGGCGACTGCTctaaaccagcagcagcaacagatgaTGGCAGCAAacgaaacagcagcagaaacaacaacagcgacaacaacaacacaaacaacaccaacaacaacaccatcaacACCATCAACGGATCGTACGGAGAAGTTGCGTGCCAAGGATCTGCTGGTTAACAAGCTGTACGAGTGCAAGCTGTGCCCAAAGGGTTTCCGCACAAAGCACGAGTTCCGCACCCATGTCTACGATAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGCCTGGACTTTGCCGATCCGGTGGATCGTCGAAGGCATTACAATAACATGGATTGCATTGTGCGGCTGCGCTGCATGACTTGCGATGCCAAACTGGAGACGCACCAGCGCTTCCTCGAGCATGTCTATCAGGATCATTTGGGTGGCGTGAGCAGTGATAATGCGTCCCAGCGCAGTTTGCTCGGCTCCCTTGGCATCGGCgttgtcagtcagtcaccCAACGACGAGtcacgcagcagcaacagcaacaatacccacaacaataacaacaataataatactaataacaacaacaacaacaatccacCTGTAACCCCGACACCCAAACTACCAACGGTagctggagcagcaacaacagctggaggaggaggaggaggaggcggatcagcatcatcatcggGCGGTCGTGATGCACCCAAGTCGCAGTATTTCTCACGCATGCCACAGGTCTGTCCGATCTGTGGCCAGCAGTACAATAACTATAACAATGTGTTGCGCCACATGGAATCGAAGCATCCCAACAAATTGCCCGAGACATACAAGTGTGTCCGTTGTGGACTGGGCTATCCGCGCATCTCCTATCTGCGGGAGCACATGACCAATGTGCATGGTGTGGACAAGAATCGGCAGACGGGCGGATTTGAGTATATTGTGAATGCCGATGCGGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTATACCGGACGATATGATTATGTGATGAAGGATCTTATGTCTATAACAAATGGTGGGACACTCgatgatgatgacgaagaTGGCGGCGACAGCGTCGGCCCCATTCCCAAAAAGATGCGACTTAATGATAGCAGCAGCCTCAACATGAGCAGCATTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTCAGCAACAATATTGGTCTATCGAATCATATGCGTTCCCATTACACAGCATCGATAACGACAAGTGCTGCTCTGGCGGCTGCCAATCGCATGACGCCCAAATCGCTGACAATAACAGCAACGCCACCGCTCGAAGTGACAGCCACAGCAACGTCGGCGTCGGCAACATCATCGTTAGCGACGGGCACAACAAATACATCAACtgcggctgcttctgctgcagcaacaaagacaacaacaacaacaagaactttGCCTGGATTTGTAACAGTGGCATCATTTGCTTCTTCCTCAACGGGAGCAGccgcatcaacagcaacaggcacaggaacagcatcaacatcagcatcatcatccgGCAAGTTGCCGCCAGCAATGGTGCATCAGACGGCCCAGGAGCAGGCGGTATTCCGTCGCAGTCTGGATCAGGCGGCCGATCGACGATTCCGTCGAATGCGCTGTCGTATCTGCCAGCGGAGATTCAGTTCGAAGAAGTCGTATCGCTACCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGTAACGCGGAGTTCGCCTACGAGAAGGGACTGAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCCATCAAGGATGAGATGATTATCAAGCAGTTCGAGTGCGATGTCTGCTCCACTGTTTACAGCTCCGAGCTGGaattgcagcagcacaagcgCAGCGTACACAAGTCACAAGCCACCACCgattcatcatcatcatcggcagcagcagccggtgGCAAACAATCATCAAACAAGtcagcgactgcaactgctACCTCCACAGCGGCGGAACTGGCGGCAGACACATCATCCCCGTCTGGCGCGGCAGGGGCGGCCACTCAGCTGCCACTCTACTGGTACCAGTGCAAATATTGTCCATCCAACTTCAACACCAACAAGAAACTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGCCTCTGGgTGCATCGCTACAAGAAGCATCCGCAGGTGCCGGATCCCGCCGAGTGCACGCTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGCAAGCCAATCACTGCCACCGGTGCCCATCAGcaggatcagcagcagcagcagcaacaaccgcaacaacaacagatgcagcagcaatatcatCAGCGAGTCATCTTCAAGCACAAAACGggagatgatgatgacgaggatgaggacgatGATCAGTTAATGGACGATGGCGGTGGCGGCAGCAATGATAGCAATGCTGGAAATGCcattgcaacagctgcagcagcagcggcgagcACAATAAAGATACGATTTCCGGAGGTGGCATGCACCATTTGCGGTGCCCGGTTCACCGATCAGGAGATGTTTACCAAGCACATACAGAAGCACGAACAGGAACTGTATGTAGACAATCCGTTGGCGGCCATGTTCGATGATGGGCCAGCGGATGCCGGACAATTTCAGATTGAGCACCAGAACGAGAATGGCGAATACGCGTGCGATTTGTGCAACAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGATCCCACTCAACGACGGCGAAGCGACAACGctgaacaacagcagcagcaacaacaacaacaacaattcgctGAGCTCATCATCGATGCTGCATCTACGCGAACTGCATGCAGTGGGTCTGATGcccaatcagcagcaacaccagaaacaggaacaacagcagcagcaggaacaacagcagcagcagcagcaacaacggacGAGCAAATCAATGAAACGGAAACGTGAACTGAAGTGCGAATACTGCGCCTCCACATtcattagcaacaacaacctgcgACGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTGCCAGAGCCGCCCGTGATTGAGGTGGATGAGCCGTTGACGTGTCGCCGCTGCGGCGATCTGAAGTTTGAGACCAAAGAGGGATGGATCGAGCATAAGCTGGCCGATGCGAGAGTGGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAATATTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGATGTGATTGTGCCGGTCGCTACCAAGCCAACATCAACGACACCAAATaatgttgcaactgcagcagcagcagcaacagttttaGCTGCCACATCACCAGTAGGTGCagtagcaaaagcagcagcagaggcggCGAAGGTAAAaacgccaacagcagcaaaggaACTTAAGTCTAAACAGCAGCTGGACAATGTGAAGCGAACGATGCAGCTGGATGGTGGGAAGCtaacaaagcaacagcagcaagaggaggaggaagaggatgATAGTGATATGGATGATGATAGCGATAGTGGcaatgatgatgaggagggcAGCACCAGTgctgacgacgatgatgaggacgacgatgatgatgaggagggcGACGTCGACGGTGATGACAAAAATGttatgaaactgaaaatgctGCACCTAAAGCCGGAAAATACAAACAACGAGgtcgacgacgatgatgaagacgaagatgatgaagatgatgaggAGGGCGACGTCGACGATGatggcaaaaatgttattaaactGAAAATGCTGCAACTAAAGCCGgtcgacgacgatgatgaagacgaagatgatgaagatgaagatgatgagGAGAGCGGCGCCGACGGCGataagaaaaatgttattaaactgaaaatgcggcaacagcagccggaaaatacaaacaccaacaacgacgtcgacgacgatgatgaagatgaagatgatgacgatgaagatgatgagGAGGGCGACGTCGACGATGATgAATCCAATgtcgacgacgatgatgaggaagatgacgacgatgacgatgacgacgacgacgacgatgatgataatgatgacgatgatgatgatggcgaagacgatgacgatgacgatggcgatatcgatgacgatgacgatgataatACAACGGTTGAGCAACTTCAGCCGAGGACCCTCAATTTCGACTATTCGTGCACCGACAGCGCCAAGCTAAATGGCAACGGTGGCAAACAGTCTGTGGCGAAATCAAagacacagccacagccaatgCTGGtcatgcacagcagcagcagcagtcgccgcGGAGATGATGGCGAGGAGGAAGTGGATGAtatggatgatgatgatgatgttgtggGTGAAGCGATGTCCATTGATGATATTATTGTGGAGGATGATGGTGTGGATGATGACGAAGTGGTTGGTGTcggtggtggtgttgttgaggatgatgatgaagatgatgaagaggatgacgatgatggcgatgatgaggatGAGCTACTTCAGACACACATTAAAAGTCATTTCCTCAATGGGCCATCGGcggggagcagcagcaacagcaacaagagcaatgGCGCCAGCAGGAgcaccaataacaacagcaacaacaacaacagtagtagtagtagtagcagcaacagcaataacaaaatcaataCCAAAAAGTCCGGCTTGGATGCAACGACGAAGACAACAACAGTTAAAGATGCAGCAACGGACGCTGCAACGGGCTTCAACTGA
Protein Sequence: MCDAATTTTPTTTAAAAVTATTAAAAQGTGAAGDNAMEEQNQRERQSCCRLCIAPASECISIINSYAADKEPLATKIQNCVNIKITSVDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWQETDKTKQQTLLGYLDLNRAENGNTIEPQQQQQQQQQQHESKMDSATTAAEKASAANILDGIPQLKKRKSLTVYVSPKQQQQAQQQQSQQHTQQQHATGARSTTKTSTAAAAVAESQPTLQTLLLQVPTAAAAATLATASTQQQQRKHQQQQHHQQQQRGKQPQHQYHQQQQQHRQSRVRQPRRQQQAATAKFRSKLFMPLDISVPALPALLPPPTPAVADAASLLLPLSLPLDFSQNPNLNPNPNQYPNPNQNLNQRYTSSLLVPPPLPLSAPAATMSSNEAAIATGCGATATATATAVTTPLLMPPVPAVPIKDEPLYDTDDDFQMRSIDESDDLMDPTMFLERSEHEGDVPLNTSDYDYTAQHGVTAAVAAASLPACAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAATATAEATRAAAGGNISAQKYRQVVMNTFTKCENGGFDYDNPEQYQQLLSHDKVDFIQKNSEFLEQYQTMTCRCCNKFFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRTKQPNFVHANAASSTATTSATAAATALNQQQQQMMAANETAAETTTATTTTQTTPTTTPSTPSTDRTEKLRAKDLLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLEHVYQDHLGGVSSDNASQRSLLGSLGIGVVSQSPNDESRSSNSNNTHNNNNNNNTNNNNNNNPPVTPTPKLPTVAGAATTAGGGGGGGGSASSSGGRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMTNVHGVDKNRQTGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDEDGGDSVGPIPKKMRLNDSSSLNMSSIANQQKECLICNAVFSNNIGLSNHMRSHYTASITTSAALAAANRMTPKSLTITATPPLEVTATATSASATSSLATGTTNTSTAAASAAATKTTTTTRTLPGFVTVASFASSSTGAAASTATGTGTASTSASSSGKLPPAMVHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSELELQQHKRSVHKSQATTDSSSSSAAAAGGKQSSNKSATATATSTAAELAADTSSPSGAAGAATQLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQPQQQQMQQQYHQRVIFKHKTGDDDDEDEDDDQLMDDGGGGSNDSNAGNAIATAAAAAASTIKIRFPEVACTICGARFTDQEMFTKHIQKHEQELYVDNPLAAMFDDGPADAGQFQIEHQNENGEYACDLCNKTFPQVIALKVHRKWHFRGDSKQIPLNDGEATTLNNSSSNNNNNNSLSSSSMLHLRELHAVGLMPNQQQHQKQEQQQQQEQQQQQQQQRTSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDLKFETKEGWIEHKLADARVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATKPTSTTPNNVATAAAAATVLAATSPVGAVAKAAAEAAKVKTPTAAKELKSKQQLDNVKRTMQLDGGKLTKQQQQEEEEEDDSDMDDDSDSGNDDEEGSTSADDDDEDDDDDEEGDVDGDDKNVMKLKMLHLKPENTNNEVDDDDEDEDDEDDEEGDVDDDGKNVIKLKMLQLKPVDDDDEDEDDEDEDDEESGADGDKKNVIKLKMRQQQPENTNTNNDVDDDDEDEDDDDEDDEEGDVDDDESNVDDDDEEDDDDDDDDDDDDDDNDDDDDDGEDDDDDDGDIDDDDDDNTTVEQLQPRTLNFDYSCTDSAKLNGNGGKQSVAKSKTQPQPMLVMHSSSSSRRGDDGEEEVDDMDDDDDVVGEAMSIDDIIVEDDGVDDDEVVGVGGGVVEDDDEDDEEDDDDGDDEDELLQTHIKSHFLNGPSAGSSSNSNKSNGASRSTNNNSNNNNSSSSSSSNSNNKINTKKSGLDATTKTTTVKDAATDAATGFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496779;
90% Identity: iTF_00496779;
80% Identity: -