Bvos000904.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus vosnesenskii
Gene Symbol
prdm10
Assembly
GCA_011952255.1
Location
NW:631620-637429[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.0038 0.24 11.2 0.2 2 23 518 539 517 539 0.95
2 11 0.00034 0.022 14.5 0.3 2 23 552 573 551 573 0.96
3 11 0.0062 0.4 10.5 3.8 1 23 590 612 590 612 0.91
4 11 0.004 0.26 11.1 2.6 2 23 621 642 620 642 0.96
5 11 0.00021 0.014 15.1 0.3 1 23 649 671 649 671 0.98
6 11 0.00045 0.029 14.1 1.8 1 23 678 700 678 701 0.95
7 11 0.00027 0.017 14.8 1.7 1 23 706 728 706 728 0.98
8 11 1.6e-05 0.001 18.6 4.1 1 23 734 757 734 757 0.96
9 11 0.0011 0.074 12.8 1.7 1 23 790 813 790 813 0.97
10 11 2.5e-05 0.0016 18.0 2.4 1 23 835 858 835 858 0.97
11 11 0.001 0.067 13.0 3.4 2 23 895 917 894 917 0.96

Sequence Information

Coding Sequence
ATGGATCCAAGGGGCCCTCCTGAGGGGGCCCCTACTAATTCCTTTGagataaataatatcgataaagtGTCTAACAATTTAGTAAATTGGTCTACAGATCATTCTTTCTCTTCACCAATGTGcgaacaacaaaaaaaaatgaataataataaactgttatttttaaCTgTGGAATATGTGGAAGATCCATCACGGGAATATTCCCGTTTATTTCCAACATATGAACAAGTTTCCTTCTCTCCTAGACCATCGTCTCCACTTTCAGATTTTGAACATCGTGTTAGTCCTCTTGACCCCAATATGAGTTCAGCTGCTAGATATTCACCTACTCCTGTGCAACTTCCACCATCTCCGTTTCATAATTCTGTTGTTGTATTACAAgattcttcttctcctttaaTATCCTCGACTGAATCAAATGAAAGAACAAATGTTAATTATGTTTCTCAATTAACGCATCCAATTGATACACAAAGTGTACAGCAGTCAGATAGTTCTACTGACTATGTTGCTAATGAAAATGAGGAACAACTAGTGTCTAGTGTTGGCAGTGAGTTGATTCTTATGCAagaAACGAATTCCGGGCTAGAATCAGCAACAGCTCCATTAATGCTAACAGGAATGCCAAGTACAGATTTTACATTAAGTAGAGATTTTCTTGTTATGCAAGATGACCAAATGAATGTTATAAATTCGTTTAAAACACAAAACCTTGATATAGATGATTCTACACATCTTTCATCAAATgcagaaaattcaaataaagaaaataatgcaGATTCTTCAGCTGCATCTAATGAACgggaaattaatgaaattttaatacctactgaagaaaaaaaagattgtgaaaaaaagaatatgaGACGTTCGAAACGTcgtataaatgataaaaaaagtttatgtTGCGATGAATGTGATGATGTGTGTACTTCACATAATGTATGTACAATAGCAGATCAACCAGTACCATCTCGTGCTATAGCGACACTGCCAGGATCATACCTTTCTATAAACAAATTATCCAATTCTGAAATTATATCAGGTGGATCAGATTATGGTGTGTTTGCAAAACGTTATATACAAAAACGTACTCAATTTGGACCTATAGAAGGTGTCTTATATCCTTATGATGGTACACCATTTAGAGATGAATTGCCATTGCTCTATGAAactgaaaataaagaatttttaaaagtagATGTTTCAAATGAAAATGCTTCAAATTGGATGCGCTTTGTTAGACCTGCATTAACATATAAAGATCAAAATTTGGTAATTTGTCAACAACGTGATGGAATAGTATTTTTGACTACAAGAAGTATTTTACCAAAGGAAGAATTAAAAGCTGGTCCTAGTACTGACTATGCAATACGTAGAAATTTAATACCACTCAAATCTACACAGGAAACGAAGGATGATAAAGAGCACAAAAATCAAATATCTAGTTGGTCACGGCTAGATGATAATAATTCCCGGCGTATGAAAGTATTTCGCggaagaaatttgaaagagaaagaaaattcaagacaaaataattctaagGAATGGAAATGTTCTGTTTGTGgtttaatttttcgaaaatcaCTTTTGCTTAACTTACACTCTCTTGTTCATGGttctgataaaataaaaactaaaattcaATCTACAGTTTGTCCGCAATGTGGACTGCAATttcaaaaacaaaaagaattgATCAATCACATTTCACAACATGGGAGATTATCTTTGCAAAAAGCAAAAATATTGACTTCTTTGTCTACATATAAGTGTTCGATGTGCTATAAACGTTTTGCGACAAAAGTACGTTTACAGCAGCACTGCTTAGTGCATGGTGCTGAAGACCAAAAACCACTGCCATGTAATATTTGCTTCAAAAGATTCATGAATAATTCGGCACTCTCTTGTCACTTGAAAACACATAGAGAAAATAAACAAGTATTTGAGTGTCCAATGTGCCGACAACTATTTAATCAAAGCATAACATTAAAAGATCATATTGAAACTCATAAAAATGAAGATGGCACATTTAGCTGTCCTTACTGCCAAagaatatttatcaaatattcgGTTATTCGTAAACATATTAGAGCACATCATTGTGAAAGAAAACACAAATGTCAAATTTGTGCAAAACGATTTGCTACAGTAGATAAATTACAGATGCATCTGCTAAAACATTCCGATCATAGaGAATTTCACTGTGCAAATTGTGGTAAACAATTTAAGAGAAAAGACAAATTAAAAGAACATATGACTAAATTACATAATTCACAGACAGCCACTGAAGAACAAATGTCGCAAGTTACACAAACTAAAAAATTTGTTCCAAAGGTAAACCCTAATGATTACAAtcgtttcatttataaatGTCACCAATGTTTGGTGGGTTTTAAACGAAGAGGAATGCTTGTAAATCATTTGGCGAAAAGACATCCAGATGTTGCGCCAGAATCTGTACCAGAGTTAAACTTACCAATTTTACGTCAAACGAGAGATTATTATTGTCAATATTGCGATAAGGTCTATAAAAGCAGCAGTAAACGTAAAGCACATATCATGAAAAATCATCCAGGAGCTGCTTTACCGCCGAGCAACCGACAAAAGGAGTCGGATTACTCCGATTTACCGAATCCAACATTTAGTCAAACTGTCGGTAGCATTACTACTACACCACAGAGTTGTCAATGGTGTCATAAACAATATGCTAGTAAAgCAAAACTTTTACAACATCAACGAAAGAAACACCCAAATTTAATGGAACCGGCTGATCAAGTACCGCGTTCACGTAATCGACAGCCACAGAATCAAAATCAGCCCCCAGTACTTATTGAAGATCACTTTGTATTGTCCGATTATATTCAGACGTGTGAAACAAATTCAGATTTTTTTAAACCAAgaataatcaaaatatctgATGATGTTGATCTAATAGGCAATGGATTAGAGATAGTTGGGCAACAATTTGTTCGTATGCGTGACATACGCTGA
Protein Sequence
MDPRGPPEGAPTNSFEINNIDKVSNNLVNWSTDHSFSSPMCEQQKKMNNNKLLFLTVEYVEDPSREYSRLFPTYEQVSFSPRPSSPLSDFEHRVSPLDPNMSSAARYSPTPVQLPPSPFHNSVVVLQDSSSPLISSTESNERTNVNYVSQLTHPIDTQSVQQSDSSTDYVANENEEQLVSSVGSELILMQETNSGLESATAPLMLTGMPSTDFTLSRDFLVMQDDQMNVINSFKTQNLDIDDSTHLSSNAENSNKENNADSSAASNEREINEILIPTEEKKDCEKKNMRRSKRRINDKKSLCCDECDDVCTSHNVCTIADQPVPSRAIATLPGSYLSINKLSNSEIISGGSDYGVFAKRYIQKRTQFGPIEGVLYPYDGTPFRDELPLLYETENKEFLKVDVSNENASNWMRFVRPALTYKDQNLVICQQRDGIVFLTTRSILPKEELKAGPSTDYAIRRNLIPLKSTQETKDDKEHKNQISSWSRLDDNNSRRMKVFRGRNLKEKENSRQNNSKEWKCSVCGLIFRKSLLLNLHSLVHGSDKIKTKIQSTVCPQCGLQFQKQKELINHISQHGRLSLQKAKILTSLSTYKCSMCYKRFATKVRLQQHCLVHGAEDQKPLPCNICFKRFMNNSALSCHLKTHRENKQVFECPMCRQLFNQSITLKDHIETHKNEDGTFSCPYCQRIFIKYSVIRKHIRAHHCERKHKCQICAKRFATVDKLQMHLLKHSDHREFHCANCGKQFKRKDKLKEHMTKLHNSQTATEEQMSQVTQTKKFVPKVNPNDYNRFIYKCHQCLVGFKRRGMLVNHLAKRHPDVAPESVPELNLPILRQTRDYYCQYCDKVYKSSSKRKAHIMKNHPGAALPPSNRQKESDYSDLPNPTFSQTVGSITTTPQSCQWCHKQYASKAKLLQHQRKKHPNLMEPADQVPRSRNRQPQNQNQPPVLIEDHFVLSDYIQTCETNSDFFKPRIIKISDDVDLIGNGLEIVGQQFVRMRDIR