Aash009546.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Aphaenogaster ashmeadi
Gene Symbol
znf423
Assembly
GCA_003063805.1
Location
NJRQ01000573.1:94390-112700[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 8.4e-06 0.00095 19.9 1.5 1 23 92 114 92 114 0.98
2 21 0.079 8.9 7.4 4.9 1 23 120 142 120 142 0.98
3 21 2.4e-06 0.00027 21.7 2.3 1 23 148 170 148 170 0.99
4 21 0.00014 0.015 16.1 0.2 1 23 176 198 176 198 0.99
5 21 0.0073 0.83 10.7 2.2 1 23 365 388 365 388 0.94
6 21 0.43 49 5.1 0.0 3 23 401 422 399 422 0.88
7 21 0.83 94 4.2 0.1 3 23 491 511 490 511 0.97
8 21 0.073 8.3 7.5 0.1 3 23 527 547 525 547 0.95
9 21 0.00097 0.11 13.4 0.3 1 23 556 579 556 579 0.92
10 21 2.3 2.6e+02 2.8 0.2 1 23 584 607 584 607 0.92
11 21 0.078 8.8 7.5 2.7 2 23 688 709 687 709 0.96
12 21 0.017 1.9 9.6 0.3 1 23 714 737 714 738 0.93
13 21 3.3 3.8e+02 2.3 0.1 2 23 802 825 801 825 0.81
14 21 3.4e-05 0.0039 18.0 1.0 2 23 841 863 840 863 0.96
15 21 0.029 3.3 8.8 0.9 1 23 872 895 872 895 0.93
16 21 0.73 83 4.4 1.2 2 23 903 924 902 924 0.97
17 21 0.011 1.2 10.1 0.0 2 23 1088 1110 1087 1110 0.92
18 21 0.14 16 6.7 0.2 1 23 1121 1144 1121 1144 0.95
19 21 1.4 1.6e+02 3.5 0.1 2 23 1157 1178 1156 1178 0.94
20 21 0.085 9.6 7.3 0.1 2 23 1187 1209 1186 1209 0.93
21 21 0.08 9 7.4 2.7 1 23 1216 1239 1216 1239 0.97

Sequence Information

Coding Sequence
ATGCTCTTCAAGGGCAACAGTTCACGTCTGGAACTGCTGATAGGGAAGATCCACGCGCACAAGGAACCGTCACAAGACGAGCAGCATAAGTCTAAAGAGGCCCTAGGAACCGGAAGTTCCTCGTGGCACAGCGAGGATGGCGGGCCCAACTCGCGTCGCGGCGGCGAGACGCCGTCTTCCTGCGCGACGCCAACATCGGCCAGCTTCCCGTCGGAGCCCGAGGTCGACGCCGACGTCGGCGTCAATCCCGACGGCAATAACCCCGCTGCCCCGTATCCCTGCCAATTCTGCGACAGGACATTCCCGCGGCTCAGCTACCTGAAGAAACACGAGCAGAGCCACGGCGATCAGATGCCGTATCGATGCAGTTGGTGCAACAGACTATTCAAGCACAAGCGCAGTCGCGATCGTCACGTGAAGCTGCACACCGGGGACAGGCGATACCGCTGCTCGAAATGTGAGGCCGCCTTCTCCAGGAGCGATCACCTGAAGATCCACCTGAAGACGCACGACACCCAGAGGCCTTACCAATGCACTGCTTGCACGAGAGGCTACAGCTCAGCCGCGGCCTTAACGTCGCACATGCAATCCCACAAGAAGCATCATCAATCGTCTTCCTCTCAGTCGGCCGGCAAGCTCCAGGACGTCGATTACGGCAGGAGAAGCGTCTCCTCGCATAGCACGTCGTCACCGCCGgtgccgtcgtcgccgtcgccttCGTTGAACCTCAGTCTGAACCCGAGGAACGTCCTGAAGACGCCGCAGGGTACCGGCAGCACTTCCACCACGCCGATTCTCAACTCGCCCTTGAAGCTTGCCTGCATGTACTGCACCCGGGACTCATTCAGCTGCATGCAGCAGCTGCAAATGCACGTGCGCACGATGCACCAGGCGATCCTCAGCGGCGCGGAGAATCTGACGCGGCCGCCGTCGCCAAGCAGAACGTCGAACGAACAGCAAGCAGTATTCTGCTCGCGCGACAAGCCGCCCGATCGCCAGGACGGCTCGAAGGACCCACGCGCGGACCGGAAATACCCTCCTGAGGAGAGAGCCGACAGGCCTGCCGGCGAACGGGACCACTACGAGAACGCGTTCACCTGCGACCAATGCACCATGAAATTCTCAACCCTGGCCTGCCTGCGCGATCATTCGCTGTCGATACACCGAGTTGACGGTGGTTTCACCGCGGCGATGGTGATATGCCCGTTGTGCGGCATTCCGTGCACCTCGACGGCAGCCTACGCCGAGCACTACGTTCTTCAGCACTGCGATAATCGTCGACCGGCGCCGACAGCTGGTATAGATTACAGCGAGACGAAGCTGAACGGCGTTTACGACAACGTTACTTCAACGAGGGACTCCAGAGTGCCGAGAAACAGGGACGTCCCGGAAGCAGCCGATCTCACGAATAAACGTCCGAACAGGCCATCCGCGGACGCCTCTGGTGGCTATACTGCCGATACCCTGCTGTGCGGCCAATGCGACGCCGCGCTGAAGGATTTCGAGTCTTTTCGCGAACACGTGGCCCGGCACCTGCAGGCTGATCACCGTAACCAGGAGATATCCAGACAACATCTGTGTCCCAAGTGCGAGGCCGTCTTCCCGGCCCGTGAGGACATGCTGGCCCACCTGACCAAGCACTACCTGGGTCAGGTCAGCAAGGAATACGCGTGCGGCGCCTGCAAGAAGTTCTATCCGCATCCGGATCAGCTTCAGAGACACTTGTTGGACGCCCACGCGCATCATCTGTACCGTTGCGCTCTGTGCCGGGACACGTTTGACTCCAAAGTAGCGATACAGGTGCACTTCGCGGTCAAGCACAGCCAGGAGTGCCGGATCTACCGATGTAGCGTGTGCGCGCTGTCCAACAACGAGAACTCGCCGCCGGGGGCGAACACGGTTCCCGGCGATGGCAGGAGCTTCTTCAGGAGCGAGGCCGAGATGGCAGCCCATGTGCGCAATGTACACGCGCCTCCTCTCGTTGCCCCGTCCTTGATGAACAACAGTCCTGTCGGAGTTACAACAAGGAGTCCAGCCTCGACCCCCGGTGTTGTCGCGACGCGCTGCGTCTTCTGCGGGACCTGCTGCAGTTCGGAGCTCGAGCTTCAACTTCACCTGGCCAGCCATTCGGCCAGTCTCTACAGGTGTCCCATCTGTAGAGAGGGTTTCGCGGTGGAATTCCTGCTGGACCGACACGTCACCCAGGTTCACCATCAGGCAGCGCAGAATCACCAGACACCGTCAGTCAGAAACAGGGAGAACGGGCGCGTTCATCGACCGGCTAGAAATCAGGAAGAAACGAAATCTCTGAAGAGGGGCCGCTCGCCAGCGTCAAGCAACAACAACTCCCTGAACCAGCGCGACAACAACAACAAACGTCCGAATTACGGCACTTCCGGTCAGCAATGCGAGCTCTGCGAACGTGGTGAATTCGCGAACGAGGCCGAGCTGCAGGCGCACAAGAAACTCGCTCACACTCCTCCCAAGCTATCCAGCAAGTCTCTATCTACCTTGAGCATGACATGCGGCTATTGCGGCGAGGTCTGTCGCTCGCGAAGCGAGTTGGAATCTCACACGAGGATCCAGCACGCGTCTAATGAGCCCGGTGGGCGTCACAAGTGCAACATCTGCGACGAGGTATGTCCGTCCGGCGCGAGCTTGGCTGAGCACAAGCTCCAGAAGCACTGCAAGATCCAGCTGAGTGACAAGTGTGTGGTGTGTCGCGGTTGTCTCACGTCGGAGAGCCAGTTCCTGGACCACGTGCAGAGGCATAGTCTGGAGAACGTGGATCCACAGCAGCGACTGGACAGCACGCTGCCTCATCTGCCCGCGCCGTGCGTCGTTTGCCGACAAACGCTGATCAGCGATCTGGAATGTCGTCTGCACGCGCGGCATCACCTACGAACGTCCTCGGGATCGCGCAGCGCCGGTTCCAGCCCAATCAGTCCTGGTGGCAAAAGCCAAAATCAAGGTTGCTGCCTCTGCTTGCGTGATTTCGCGGCCGAGGACTTTGTCAACCTTCCGCCCAATCCTGCCAGTACAAGCGGACAGCTGCTCAGAGTTTGCAAACCATGCTACATGCGACACTCCCAGGGACTGCCTATTCTGAACTCGACGACCTACGAGCATCGGGCCAAATACGAGGCGGCTTGGCTCGCGAGCAAGGACGGCCAGTGGGACGAATCTAAGGACAAGTGGGAGCACGAGAGAGGACCCAAGATAGAGGATAGATCCAGGAACGAAGGAAATGCGAATAAGAAACGGTGCGAAGAGTGCGGGGTGAAGTTTGAGGATCCCGAAGAGGCGGAGAAGCATAGGATCGCCGAGCACGAAAAGGCTGCCGGCGGTGGCTCGAATACCTACACCTGCATACAGTGTCAAGTGTCGTTTCCAACTGAAGCCAAGATTCAGCAACACGTGAGGAAGGAACACTTGGAGGCATCCGGGAAAGCCTCCTTGGAGGCTTTACGTTGCCACTTGTGCTTATTCGAGGCCGCCAGTCCTATGCAGCTGCAAATTCACTTAATAGAGCACACTTTCGTCGGCTGTACCGCCCTTAGCTGTTACATCTGCCAGTCGCTCTTTACAACTCCCATTGGCCTTCAGAATCATTTACTGCAGGAACACGGCTTGGACGCGCGACCGTACGATTGCTCCAAATGCACACTCAAGTTCTTCTTCAACGCGGAACTGGACCACCACGTACTGACCTTCCATCGTCCGGGAGAAGAGAGCCACCCTCCGTCGGCCGAGAACGCTCGCGAGAAGAATCGCGAATCCGAGAAACGCGACGGCGGTGTAACGGTGAAGGAGGAAGTAGTGCAAGGCGGCAAGGAAGAGGATGAAGAGGAGGAAGTGAACGTGGACGATCAGGTGGGACAGAGGCAGCACGAGGAAGTTGGACGAGAGGAGCAGAAGCTGAAGACGGAAGTAGACGGCGAGACGACATCCGGCAGAATGGAATCGTGA
Protein Sequence
MLFKGNSSRLELLIGKIHAHKEPSQDEQHKSKEALGTGSSSWHSEDGGPNSRRGGETPSSCATPTSASFPSEPEVDADVGVNPDGNNPAAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCNRLFKHKRSRDRHVKLHTGDRRYRCSKCEAAFSRSDHLKIHLKTHDTQRPYQCTACTRGYSSAAALTSHMQSHKKHHQSSSSQSAGKLQDVDYGRRSVSSHSTSSPPVPSSPSPSLNLSLNPRNVLKTPQGTGSTSTTPILNSPLKLACMYCTRDSFSCMQQLQMHVRTMHQAILSGAENLTRPPSPSRTSNEQQAVFCSRDKPPDRQDGSKDPRADRKYPPEERADRPAGERDHYENAFTCDQCTMKFSTLACLRDHSLSIHRVDGGFTAAMVICPLCGIPCTSTAAYAEHYVLQHCDNRRPAPTAGIDYSETKLNGVYDNVTSTRDSRVPRNRDVPEAADLTNKRPNRPSADASGGYTADTLLCGQCDAALKDFESFREHVARHLQADHRNQEISRQHLCPKCEAVFPAREDMLAHLTKHYLGQVSKEYACGACKKFYPHPDQLQRHLLDAHAHHLYRCALCRDTFDSKVAIQVHFAVKHSQECRIYRCSVCALSNNENSPPGANTVPGDGRSFFRSEAEMAAHVRNVHAPPLVAPSLMNNSPVGVTTRSPASTPGVVATRCVFCGTCCSSELELQLHLASHSASLYRCPICREGFAVEFLLDRHVTQVHHQAAQNHQTPSVRNRENGRVHRPARNQEETKSLKRGRSPASSNNNSLNQRDNNNKRPNYGTSGQQCELCERGEFANEAELQAHKKLAHTPPKLSSKSLSTLSMTCGYCGEVCRSRSELESHTRIQHASNEPGGRHKCNICDEVCPSGASLAEHKLQKHCKIQLSDKCVVCRGCLTSESQFLDHVQRHSLENVDPQQRLDSTLPHLPAPCVVCRQTLISDLECRLHARHHLRTSSGSRSAGSSPISPGGKSQNQGCCLCLRDFAAEDFVNLPPNPASTSGQLLRVCKPCYMRHSQGLPILNSTTYEHRAKYEAAWLASKDGQWDESKDKWEHERGPKIEDRSRNEGNANKKRCEECGVKFEDPEEAEKHRIAEHEKAAGGGSNTYTCIQCQVSFPTEAKIQQHVRKEHLEASGKASLEALRCHLCLFEAASPMQLQIHLIEHTFVGCTALSCYICQSLFTTPIGLQNHLLQEHGLDARPYDCSKCTLKFFFNAELDHHVLTFHRPGEESHPPSAENAREKNRESEKRDGGVTVKEEVVQGGKEEDEEEEVNVDDQVGQRQHEEVGREEQKLKTEVDGETTSGRMES