Basic Information

Insect: Harpagoxenus sublaevis
Gene Symbol: znf423
Assembly: GCA_030770355.1
Location: JASTWR010000111.1:249531-255150[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 3.9 7.1e+02 2.4 0.6 13 23 19 29 18 29 0.92

2 19 1.9e-05 0.0035 19.1 0.4 1 23 35 57 35 57 0.99

3 19 0.0079 1.4 10.9 2.2 1 23 224 247 224 247 0.94

4 19 0.46 84 5.3 0.0 3 23 260 281 258 281 0.88

5 19 0.9 1.6e+02 4.4 0.1 3 23 349 369 348 369 0.97

6 19 0.00061 0.11 14.3 1.0 3 23 386 406 384 406 0.95

7 19 0.001 0.19 13.6 0.3 1 23 415 438 415 438 0.92

8 19 2.5 4.5e+02 3.0 0.2 1 23 443 466 443 466 0.92

9 19 0.084 15 7.6 2.7 2 23 547 568 546 568 0.96

10 19 0.017 3.1 9.8 0.1 1 23 573 596 573 597 0.93

11 19 3.6 6.5e+02 2.5 0.1 2 23 662 685 661 685 0.81

12 19 3.1e-05 0.0057 18.4 0.8 2 23 701 723 700 723 0.96

13 19 0.031 5.6 9.0 0.9 1 23 732 755 732 755 0.93

14 19 1 1.8e+02 4.2 1.0 2 23 763 784 762 784 0.96

15 19 0.012 2.2 10.3 0.0 2 23 949 971 948 971 0.92

16 19 0.15 27 6.8 0.2 1 23 982 1005 982 1005 0.95

17 19 0.99 1.8e+02 4.3 0.3 2 23 1018 1039 1017 1039 0.94

18 19 0.017 3 9.8 0.2 2 23 1048 1070 1047 1070 0.94

19 19 0.08 15 7.7 2.6 1 23 1077 1100 1077 1100 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	3.9	7.1e+02	2.4	0.6	13	23	19	29	18	29	0.92
2	19	1.9e-05	0.0035	19.1	0.4	1	23	35	57	35	57	0.99
3	19	0.0079	1.4	10.9	2.2	1	23	224	247	224	247	0.94
4	19	0.46	84	5.3	0.0	3	23	260	281	258	281	0.88
5	19	0.9	1.6e+02	4.4	0.1	3	23	349	369	348	369	0.97
6	19	0.00061	0.11	14.3	1.0	3	23	386	406	384	406	0.95
7	19	0.001	0.19	13.6	0.3	1	23	415	438	415	438	0.92
8	19	2.5	4.5e+02	3.0	0.2	1	23	443	466	443	466	0.92
9	19	0.084	15	7.6	2.7	2	23	547	568	546	568	0.96
10	19	0.017	3.1	9.8	0.1	1	23	573	596	573	597	0.93
11	19	3.6	6.5e+02	2.5	0.1	2	23	662	685	661	685	0.81
12	19	3.1e-05	0.0057	18.4	0.8	2	23	701	723	700	723	0.96
13	19	0.031	5.6	9.0	0.9	1	23	732	755	732	755	0.93
14	19	1	1.8e+02	4.2	1.0	2	23	763	784	762	784	0.96
15	19	0.012	2.2	10.3	0.0	2	23	949	971	948	971	0.92
16	19	0.15	27	6.8	0.2	1	23	982	1005	982	1005	0.95
17	19	0.99	1.8e+02	4.3	0.3	2	23	1018	1039	1017	1039	0.94
18	19	0.017	3	9.8	0.2	2	23	1048	1070	1047	1070	0.94
19	19	0.08	15	7.7	2.6	1	23	1077	1100	1077	1100	0.97

Sequence Information

Coding Sequence: ATGTCATCGCGCGCGCTTAATGTGGTCGCCCTGACGTCGATATCCCACCAACCAAACGATCACCTGAAGATTCACTTGAAGACGCACGACACCCAGAGGCCTTATCAATGCACGACTTGCACGAGAGGCTACAGCTCAGCCGCGGCCTTAACGTCGCACATGCAATCCCACAAGAAGCATCCCCAATCATCGTCCTCTCAGTCGGCCGGCAAGCTCCAGGACATCGATTACGGTAGGAGAAGCGTCTCCTCGCACAGCACGTCGTCACCGCCGGTGCCGTcgtcaccgtcgccgtcgttgAATCTCACTCTGAACCCGAGGAACCCCCTGAAAACGTCGCAGGGTACCGGCAGCACCTCCACCACGCCGATTCTCAACTCGCCCTTGAAGCTCGCCTGCATGTACTGCACCCGGGACTCGTTCAGCTGCATGCAGCAGCTACAGATTCACGTGCGCACGATGCACCAGGCGATCCTCAGCGGCGCGGAAGGTCTCGCGCGACCACCGTCGCCAAGCAGAACGTCGAACGAGCAGCAGGGGGTGTTTTGCTCGCGCGATAAGCCACCCGATCGCCAGGACAGCTCGAAGGACTCGCGTCCAGACCGGAAGCACCCGCCTGAGGAGAGAGCCGACAGACCTGCCGGCGAACGGGACCACTACGAGAACGCCTTCACCTGCGATCAATGTACCATGAAATTCTCCACCCTGGCCTGCCTGCGCGATCATTCGCTGTCGATACATCGGGTGGACAGTGGTTTCAGCGCTACGATGGTGATATGCCCGTTGTGCGGCATTCCGTGCACCTCGACAGCAGCCTACGCCGAGCACTACGTTCTCCAGCACTGCGAGAATCGCCGACCGGCGCCGGCAACCAGTATAGATTACAGCGAGGCGAAACTGAACGGCGTTTACGACAGTGCTCCAGCGAGAGACTCCAGGGTGCCGAGAGGCAGGGATGTTCAGGAGGCCGCCGATCTCACGAATAAACGTCCGACCAGGCCGTCCGCGGACGCCGCTGGTGGTTACACCGCCGATACCCTGTTGTGCGGCCAGTGCGACGCCGCGCTGAAGGACTTCGAGTCCTTTCGCGAACACGTGGCCCGGCACCTGCAGGCCGACCACCGCAACCAGGAGATATCCAGCAGGCAGCATCTGTGTCCAAAGTGCGAGACCGTCTTCTCAACCCGCGAGGACATGCTGGCACATCTGACCAAGCACTATCTGGGCCAGGTCAGCAAGGAATACGCGTGCGGGGCCTGCAAAAAGTTCTACCCGCATCCGGATCAGCTTCAGAGACACTTGTTGGACGCCCACGCGCATCATCTCTACCGTTGCGCTCTGTGCCGGGACACGTTCGACTCCAAGGTGGCGATACAGGTCCACTTCGCGGTCAAGCACAGCCAGGAGTGCCGGATCTACCGATGTAGCGTGTGCACTCTGTCCAACAACGAGAACTCGCCGCCGGGTGCGAACGCGGCTTCCGGCGACGGCAGGAGCTTCTTCAGGAGCGAGGCCGAGATGGCGGCCCACGTGCGCAATGTACACGCGCCTCCTCCGGTCGTCCCGTCCCTGATAAATAACAGTCCTGTCGGTGCTGCAACGAGAAGCCCGGCCTCGACGCCCGGCGTTGTCGCGACGCGCTGCGTATTCTGTGGGACCTGCTGCAGTTCGGAGCTCGAGCTTCAGCTTCACCTGGCCAGCCACTCGGCCAGTCTCTACAGGTGTCCCATCTGCAGGGAGGGCTTCGCGGTGGAATTCCTGTTGGATCGACACGTCGCCCAGGTTCACCATCAAGCATCTCAGAATCACCAGGCGCCGTCGATCAGAAACAGGGAGAACGGGCGTGTTCATCGACCTGCCAGAAGTCAGGAAGAAACGAAATCTCTGAAGAGGGGCCGTTCGCCAGCGTCAAGCAACAACAATTCTTTGAACCAGCGCGACAACAACAACAAACGTCCGAATTACGGCGCTTCCGCGGGTCAGCAATGCGAGCTCTGCGAGCGCGGTGAATTCGCGAACGAGGCCGAGCTGCAGGCACACAAGAAACTCGCCCACACACCTCCTAAGCTGTCCAACAAGTCTCTATCTACCTTGAGCGTGACGTGTGGCTATTGCGGCGAGGTCTGTCGCTCGCGAAGCGAGCTGGAATCTCACACGAGGATTCAGCACGCGTCCAATGAACCCGGTGGTCGTCACAAGTGCAATATCTGCGACGAGGTGTGCCCGTCCGGCGCGAGTCTGGCCGAGCACAAGCTGCAGAAGCACTGCAAGATCCAGCTGAGCGACACGTGCGTGGTGTGTCGCGGTTGTCTTACGTCGGAGAGCCAATTCCTGGACCACGTGCAAAGGCATAGCCTGGAGAACGTGGATCCGCAACAACGACTGGACAGTACGCTGGCTCATCTGCCCGCGCCATGCGTCGTCTGCCGACAGACGCTGATCAGCGATCTGGAGTGTCGTCTGCACGCGCGGCATCACCTACGAACGTCCTCGGGATCGCGCAGCACCGGCTCCAGCCCGACCAGCCCTGGTGGCGGCAAAAGCCAGAATCAAGGTTGCTGCCTGTGCTTGCGCGACTTCGCGGCCGAGGACTTTGTAAATCTACCACCCAATCCTGCCAGTACAAGCGGACAGCTGCTCAGAGTCTGCAAACCGTGCTACATGCGACACTCTCAGGGACTGCCTATTCTGAACTCGACAACCTACGAGCATCGGGCCAAATACGAGGCGGCCTGGCTCGCGAGCAAGGACGGCCAGTGGGACGAGTCCAAGGACAAGTGGGAACACGAAAGGGGACTCAAGGTAGAGGATCGATCCAGGAACGAGGGGAACGCGAATAAGAAACGGTGCGAAGAGTGCGGGGTGAAGTTCGAAGATCCTGAAGAGGCTGAGAAGCACAGGATCGCCGAGCATGAAAAGGCCGCCATCGGTGGCTCGAATACCTACACCTGCATACAGTGTCAAGTGTCGTTCCCAACTGAAGCCAAaattcagcaacacgtgaggaaGGAACATTTGGAGGCATCTGGGAAAGCCTCCTTGGAGGCTTTACGGTGCCACTTGTGCTTATTCGAGGCCGCCAGTCCTACGCAGCTGCAAATGCACTTAATAGAGCACACTTTCGCCGGTTGTGCCGCTCTTAGCTGTTACATCTGCCAGTCGCTCTTCACAACTTCCATTGCCCTTCAGAATCATATGCTGCAGGAACACGGACTGGACGCGCGACCGTACGATTGCTCCAAGTGCACGCTCAAGTTCTTCTTCAGCGCGGAACTGGACCACCACGTACTGACCTTCCACCGTCCAGGGGAAGAGATCCACCCTTCATCGACCGAGAACGCTCGCGAAAAGAATCGCGAGTCTGAGAAGCGCGATAGTGCAGGTGTGACGGTGAAGGAGGAAGTGGTGCAAAGCGGcaaggaagaagaggaggaggaggaggaagtaAATGTGGATGATCAAGTGGGGCAAGGGCATCCCGAAGAAGTTGGACGAGAGGATCAGAAGCTGAAGACGGAAGTAAACGGCGAGACATCCGGCAGGATGGAATCGTGA
Protein Sequence: MSSRALNVVALTSISHQPNDHLKIHLKTHDTQRPYQCTTCTRGYSSAAALTSHMQSHKKHPQSSSSQSAGKLQDIDYGRRSVSSHSTSSPPVPSSPSPSLNLTLNPRNPLKTSQGTGSTSTTPILNSPLKLACMYCTRDSFSCMQQLQIHVRTMHQAILSGAEGLARPPSPSRTSNEQQGVFCSRDKPPDRQDSSKDSRPDRKHPPEERADRPAGERDHYENAFTCDQCTMKFSTLACLRDHSLSIHRVDSGFSATMVICPLCGIPCTSTAAYAEHYVLQHCENRRPAPATSIDYSEAKLNGVYDSAPARDSRVPRGRDVQEAADLTNKRPTRPSADAAGGYTADTLLCGQCDAALKDFESFREHVARHLQADHRNQEISSRQHLCPKCETVFSTREDMLAHLTKHYLGQVSKEYACGACKKFYPHPDQLQRHLLDAHAHHLYRCALCRDTFDSKVAIQVHFAVKHSQECRIYRCSVCTLSNNENSPPGANAASGDGRSFFRSEAEMAAHVRNVHAPPPVVPSLINNSPVGAATRSPASTPGVVATRCVFCGTCCSSELELQLHLASHSASLYRCPICREGFAVEFLLDRHVAQVHHQASQNHQAPSIRNRENGRVHRPARSQEETKSLKRGRSPASSNNNSLNQRDNNNKRPNYGASAGQQCELCERGEFANEAELQAHKKLAHTPPKLSNKSLSTLSVTCGYCGEVCRSRSELESHTRIQHASNEPGGRHKCNICDEVCPSGASLAEHKLQKHCKIQLSDTCVVCRGCLTSESQFLDHVQRHSLENVDPQQRLDSTLAHLPAPCVVCRQTLISDLECRLHARHHLRTSSGSRSTGSSPTSPGGGKSQNQGCCLCLRDFAAEDFVNLPPNPASTSGQLLRVCKPCYMRHSQGLPILNSTTYEHRAKYEAAWLASKDGQWDESKDKWEHERGLKVEDRSRNEGNANKKRCEECGVKFEDPEEAEKHRIAEHEKAAIGGSNTYTCIQCQVSFPTEAKIQQHVRKEHLEASGKASLEALRCHLCLFEAASPTQLQMHLIEHTFAGCAALSCYICQSLFTTSIALQNHMLQEHGLDARPYDCSKCTLKFFFSAELDHHVLTFHRPGEEIHPSSTENAREKNRESEKRDSAGVTVKEEVVQSGKEEEEEEEEVNVDDQVGQGHPEEVGREDQKLKTEVNGETSGRMES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01406753;
90% Identity: iTF_00126199;
80% Identity: -