Basic Information

Insect: Aphaenogaster picea
Gene Symbol: znf423
Assembly: GCA_003063865.1
Location: NJRM01000114.1:535682-554538[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 8.5e-06 0.00095 19.9 1.5 1 23 92 114 92 114 0.98

2 21 0.079 8.9 7.4 4.9 1 23 120 142 120 142 0.98

3 21 2.4e-06 0.00027 21.7 2.3 1 23 148 170 148 170 0.99

4 21 0.00014 0.015 16.1 0.2 1 23 176 198 176 198 0.99

5 21 0.0074 0.83 10.7 2.2 1 23 365 388 365 388 0.94

6 21 0.43 49 5.1 0.0 3 23 401 422 399 422 0.88

7 21 0.84 94 4.2 0.1 3 23 490 510 489 510 0.97

8 21 0.074 8.3 7.5 0.1 3 23 526 546 524 546 0.95

9 21 0.00098 0.11 13.5 0.3 1 23 555 578 555 578 0.92

10 21 2.3 2.6e+02 2.8 0.2 1 23 583 606 583 606 0.92

11 21 0.078 8.8 7.5 2.7 2 23 687 708 686 708 0.96

12 21 0.017 1.9 9.6 0.3 1 23 713 736 713 737 0.93

13 21 4.5 5e+02 1.9 0.1 2 23 801 824 800 824 0.81

14 21 0.00017 0.019 15.9 1.0 2 23 840 862 839 862 0.96

15 21 0.029 3.3 8.8 0.9 1 23 871 894 871 894 0.93

16 21 0.74 83 4.4 1.2 2 23 902 923 901 923 0.97

17 21 0.011 1.3 10.1 0.0 2 23 1087 1109 1086 1109 0.92

18 21 0.14 16 6.7 0.2 1 23 1120 1143 1120 1143 0.95

19 21 1.4 1.6e+02 3.5 0.1 2 23 1156 1177 1155 1177 0.94

20 21 0.086 9.7 7.3 0.1 2 23 1186 1208 1185 1208 0.93

21 21 0.08 9 7.4 2.7 1 23 1215 1238 1215 1238 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	8.5e-06	0.00095	19.9	1.5	1	23	92	114	92	114	0.98
2	21	0.079	8.9	7.4	4.9	1	23	120	142	120	142	0.98
3	21	2.4e-06	0.00027	21.7	2.3	1	23	148	170	148	170	0.99
4	21	0.00014	0.015	16.1	0.2	1	23	176	198	176	198	0.99
5	21	0.0074	0.83	10.7	2.2	1	23	365	388	365	388	0.94
6	21	0.43	49	5.1	0.0	3	23	401	422	399	422	0.88
7	21	0.84	94	4.2	0.1	3	23	490	510	489	510	0.97
8	21	0.074	8.3	7.5	0.1	3	23	526	546	524	546	0.95
9	21	0.00098	0.11	13.5	0.3	1	23	555	578	555	578	0.92
10	21	2.3	2.6e+02	2.8	0.2	1	23	583	606	583	606	0.92
11	21	0.078	8.8	7.5	2.7	2	23	687	708	686	708	0.96
12	21	0.017	1.9	9.6	0.3	1	23	713	736	713	737	0.93
13	21	4.5	5e+02	1.9	0.1	2	23	801	824	800	824	0.81
14	21	0.00017	0.019	15.9	1.0	2	23	840	862	839	862	0.96
15	21	0.029	3.3	8.8	0.9	1	23	871	894	871	894	0.93
16	21	0.74	83	4.4	1.2	2	23	902	923	901	923	0.97
17	21	0.011	1.3	10.1	0.0	2	23	1087	1109	1086	1109	0.92
18	21	0.14	16	6.7	0.2	1	23	1120	1143	1120	1143	0.95
19	21	1.4	1.6e+02	3.5	0.1	2	23	1156	1177	1155	1177	0.94
20	21	0.086	9.7	7.3	0.1	2	23	1186	1208	1185	1208	0.93
21	21	0.08	9	7.4	2.7	1	23	1215	1238	1215	1238	0.97

Sequence Information

Coding Sequence: ATGCTCTTCAAGGGCAACAGTTCACGTCTGGAACTGCTGATAGGGAAGATCCACGCGCACAAGGAACCGTCACAAGACGAGCAGCATAAGTCTAAAGAGGCCCTAGGAACCGGAAGTTCCTCGTGGCACAGCGAGGATGGCGGGCCCAACTCGCGTCGCGGCGGCGAGACGCCGTCCTCCTGCGCGACGCCAACATCGGCCAGCTTCCCGTCGGAGCCCGAGGTCGACGCCGACGTCGGCGTCAATCCCGACGGCAATAACCCCGCTGCCCCGTATCCCTGCCAATTCTGCGACCGGACATTCCCGCGGCTCAGCTACCTGAAGAAACACGAGCAGAGCCACGGCGATCAGATGCCGTATCGATGCAGTTGGTGCAACAGACTATTCAAGCACAAGCGCAGTCGCGATCGTCACGTGAAGCTGCACACCGGGGACAGGCGATACCGCTGCTCGAAATGTGAGGCCGCCTTCTCCAGGAGCGATCACCTGAAGATCCACCTGAAGACGCACGACACCCAGAGGCCTTACCAATGCACTGCTTGCACGAGAGGCTACAGCTCAGCCGCGGCCTTAACGTCGCACATGCAATCCCACAAGAAGCATCATCAATCGTCGTCCTCTCAGTCGGCCGGCAAGCTCCAGGACGTCGATTACGGCAGGAGAAGCGTCTCCTCGCATAGCACGTCGTCACCGCCGgtgccgtcgtcgccgtcgccttCGTTGAACCTCAGTCTGAATCCGAGGAACGTCCTGAAGACGCCGCAGGGTACCGGCAGCACTTCCACCACGCCGATTCTCAACTCGCCCTTGAAGCTTGCCTGCATGTACTGCACCCGGGACTCATTCAGCTGCATGCAGCAGCTGCAGATGCACGTGCGCACGATGCACCAGGCGATCCTCAGCGGCGCGGAGAATCTGACGCGGCCGCCGTCGCCAAGCAGAACGTCGAACGAACAGCAAGCAGTATTCTGCTCGCGCGACAAGCCGCCCGATCGCCAGGACGGCTCGAAGGACCCACGCGCGGACCGGAAATACCCTCCTGAGGAGAGAGCCGACAGGCCTGCCGGCGAACGGGACCACTACGAGAACGCGTTCACCTGCGACCAATGCACCATGAAATTCTCAACCCTGGCCTGCCTGCGCGATCATTCGCTGTCGATACACCGAGTTGACGGTGGTTTCAGCGCGGCGATGGTGATATGCCCGTTGTGCGGCATTCCGTGCACCTCGACGGCAGCCTACGCCGAGCACTACGTTCTTCAGCACTGCGATAATCGTCGACCGGCGCCGACAGCTGGTATAGATTACAGCGAGACGAAGCTGAATGGCGTTTACGACAGTACTTCAACGAGGGACTCCAGAGTGCCGAGAAACAGGGACGTCCCGGAAGCCGCCGATCTCACGAATAAACGTCCGAACAGGCCATCCGCGGACGCCTCTGGTGGCTATACTGCCGATACCCTGCTGTGCGGCCAATGCGACGCCGCGCTGAAGGATTTCGAGTCCTTTCGCGAACACGTGGCCCGGCACCTGCAGGCTGATCATCGTAACCAGGAGATATCCAGACAACATCTGTGTCCCAAGTGCGAGGCCGTCTTCCCGGCCCGTGAGGACATGCTGGCCCACCTGACCAAGCACTACCTGGGTCAGGTCAGCAAGGAATACGCGTGCGGCGCCTGCAAGAAGTTCTATCCGCATCCGGATCAGCTTCAGAGACACTTGTTGGACGCCCACGCGCATCATCTGTACCGTTGCGCTCTGTGCCGGGACACGTTTGACTCCAAAGTAGCGATACAGGTGCACTTTGCGGTCAAGCACAGCCAGGAGTGCCGGATCTACCGATGTAGCGTGTGCGCGCTGTCCAACAACGAGAACTCGCCGCCGGGGGCGAACACGGTTCCCGGCGATGGTAGGAGCTTCTTCAGGAGCGAGGCCGAGATGGCAGCCCATGTGCGCAATGTACACGCGCCTCCTCCCGTTGCCCCGTCCTTGATGAACAGCAGTCCTGTCGGAGTTACAACAAGGAGTCCAGCCTCGACCCCCGGTGTTGTCGCGACGCGCTGCGTCTTCTGCGGGACCTGCTGCAGTTCGGAGCTCGAGCTTCAACTTCACCTGGCCAGCCACTCGGCCAGTCTCTACAGGTGTCCCATCTGCAGGGAGGGTTTCGCGGTGGAATTCCTGCTGGACCGACACGTCACCCAGGTTCACCATCAGGCAGCGCAGAATCACCAGACACCGTCAGTCAGAAACAGGGAGAACGGGCGCGTTCATCGACCGGCTAGAAATCAGGAAGAAACGAAATCTCTGAAGAGGGGCCGCTCGCCAGCGTCAAGCAACAACAACTCCCTGAACCAGCGCGACAACAACAACAAACGTCCGAATTACGGCACTTCCGGTCAGCAATGCGAGCTCTGCGAACGTGGTGAATTCGCAAGCGAGGCCGAGCTGCAGGCGCACAAGAAACTCGCTCACACTCCTCCCAAGCTATCCAGCAAATCTCTATCTACCTTGAGCATGACATGCGGCTATTGCGGCGAGGTTTGTCGCTCGCGAAACGAGTTGGAATCTCACACGAGGATCCAGCACGCGTCTAATGAGCCCGGTGGGCGTCACAAGTGCAACATCTGCGACGAGGTATGTCCGTCCGGCGCGAGCTTGGCTGAGCACAAGCTCCAGAAGCACTGCAAGATCCAGCTGAGTGACAAGTGTGTGGTGTGTCGCGGTTGTCTCACGTCGGAGAGCCAGTTCCTGGACCACGTGCAGAGGCATAGTCTGGAGAACGTGGATCCACAGCAGCGACTGGACAGCACGCTGCCTCATCTGCCCGCGCCGTGCGTCGTCTGCCGACAAACGCTGATCAGCGATCTGGAATGTCGTTTGCACGCGCGGCATCATCTACGAACGTCCTCGGGATCGCGCAGCGCCGGTTCCAGCCCAATCAGTCCTGGTGGCAAAAGTCAAAATCAAGGTTGCTGCCTCTGCTTGCGTGATTTCGCGGCCGAGGACTTTGTCAACCTTCCGCCTAATCCTGCCAGTACAAGCGGACAGCTGCTCAGAGTTTGCAAACCATGCTACATGCGACACTCCCAGGGACTGCCTATTCTGAACTCGACGACCTACGAGCATCGGGCCAAATACGAGACGGCTTGGCTCGCGAGCAAGGACGGCCAGTGGGACGAATCTAAGGACAAGTGGGAGCACGAGAGAGGACCCAAGGTAGAGGATAGATCCAGGAACGAAGGAAATGCGAATAAGAAACGGTGCGAAGAGTGCGGGGTGAAGTTTGAGGATCCCGAAGAGGCGGAGAAGCATAGGATTGCCGAACACGAAAAGGCTGCCGGCGGTGGCTCGAATACCTACACCTGCATACAGTGTCAAGTGTCGTTTCCAACTGAAGCCAAGATTCAGCAACACGTGAGGAAGGAACACTTGGAGGCATCCGGGAAAGCCTCCTTGGAGGCTTTACGTTGCCACTTGTGCTTATTCGAGGCCGCCAGTCCTATGCAGCTGCAAATTCACTTAATAGAGCACACTTTCGCCGGCTGTACCGCCCTTAGCTGTTACATCTGCCAGTCGCTCTTCACAACTCCCATTGGCCTTCAGAATCATTTACTGCAGGAACACGGCTTGGACGCGCGACCGTACGATTGCTCCAAATGCACACTCAAGTTCTTCTTCAACGCGGAACTGGACCACCACGTACTGACCTTCCATCGTCCGGGAGAAGAGAGCCACCCTCCGTCGGCCGAGAACGCTCGCGAGAAGAATCGCGAATCCGAGAAACGCGATGGCGGTGTAACGGTGAAGGAGGAAGTGGTGCAAGGCGGCAAGGAAGAGGATGAAGAGGAGGAAGTGAACGTGGACGATCAGGTGGGACAGAGGCAGCACGAGGAAGTTGGACGAGAGGAGCAGAAGCTGAAGACGGAAGTAGACGGCGAGACGACATCCGGCAGAATGGAATCGTGA
Protein Sequence: MLFKGNSSRLELLIGKIHAHKEPSQDEQHKSKEALGTGSSSWHSEDGGPNSRRGGETPSSCATPTSASFPSEPEVDADVGVNPDGNNPAAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCNRLFKHKRSRDRHVKLHTGDRRYRCSKCEAAFSRSDHLKIHLKTHDTQRPYQCTACTRGYSSAAALTSHMQSHKKHHQSSSSQSAGKLQDVDYGRRSVSSHSTSSPPVPSSPSPSLNLSLNPRNVLKTPQGTGSTSTTPILNSPLKLACMYCTRDSFSCMQQLQMHVRTMHQAILSGAENLTRPPSPSRTSNEQQAVFCSRDKPPDRQDGSKDPRADRKYPPEERADRPAGERDHYENAFTCDQCTMKFSTLACLRDHSLSIHRVDGGFSAAMVICPLCGIPCTSTAAYAEHYVLQHCDNRRPAPTAGIDYSETKLNGVYDSTSTRDSRVPRNRDVPEAADLTNKRPNRPSADASGGYTADTLLCGQCDAALKDFESFREHVARHLQADHRNQEISRQHLCPKCEAVFPAREDMLAHLTKHYLGQVSKEYACGACKKFYPHPDQLQRHLLDAHAHHLYRCALCRDTFDSKVAIQVHFAVKHSQECRIYRCSVCALSNNENSPPGANTVPGDGRSFFRSEAEMAAHVRNVHAPPPVAPSLMNSSPVGVTTRSPASTPGVVATRCVFCGTCCSSELELQLHLASHSASLYRCPICREGFAVEFLLDRHVTQVHHQAAQNHQTPSVRNRENGRVHRPARNQEETKSLKRGRSPASSNNNSLNQRDNNNKRPNYGTSGQQCELCERGEFASEAELQAHKKLAHTPPKLSSKSLSTLSMTCGYCGEVCRSRNELESHTRIQHASNEPGGRHKCNICDEVCPSGASLAEHKLQKHCKIQLSDKCVVCRGCLTSESQFLDHVQRHSLENVDPQQRLDSTLPHLPAPCVVCRQTLISDLECRLHARHHLRTSSGSRSAGSSPISPGGKSQNQGCCLCLRDFAAEDFVNLPPNPASTSGQLLRVCKPCYMRHSQGLPILNSTTYEHRAKYETAWLASKDGQWDESKDKWEHERGPKVEDRSRNEGNANKKRCEECGVKFEDPEEAEKHRIAEHEKAAGGGSNTYTCIQCQVSFPTEAKIQQHVRKEHLEASGKASLEALRCHLCLFEAASPMQLQIHLIEHTFAGCTALSCYICQSLFTTPIGLQNHLLQEHGLDARPYDCSKCTLKFFFNAELDHHVLTFHRPGEESHPPSAENAREKNRESEKRDGGVTVKEEVVQGGKEEDEEEEVNVDDQVGQRQHEEVGREEQKLKTEVDGETTSGRMES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01406753;
90% Identity: iTF_00126199;
80% Identity: -