Sfug021587.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Solenopsis fugax
Gene Symbol
topi
Assembly
GCA_003595255.1
Location
QKQZ01010167.1:13219-15617[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.004 0.61 11.5 2.0 1 23 240 262 240 262 0.95
2 16 0.064 9.6 7.7 1.1 2 23 269 291 268 291 0.95
3 16 0.0032 0.48 11.8 0.2 2 21 298 317 297 318 0.92
4 16 0.00046 0.07 14.4 1.0 1 23 325 347 325 347 0.96
5 16 1e-06 0.00015 22.8 2.2 1 23 353 375 353 375 0.98
6 16 0.0059 0.88 11.0 0.2 2 23 387 409 386 409 0.94
7 16 0.019 2.9 9.3 6.5 1 21 425 445 425 447 0.95
8 16 3.4 5.2e+02 2.2 0.2 1 23 453 475 453 475 0.90
9 16 0.32 48 5.5 1.1 1 23 485 508 485 508 0.92
10 16 0.033 5 8.6 0.2 1 21 522 542 522 543 0.91
11 16 0.0044 0.67 11.3 0.1 1 23 548 570 548 570 0.98
12 16 2e-06 0.0003 21.9 3.1 1 23 576 598 576 598 0.98
13 16 0.00014 0.02 16.1 0.2 1 23 604 627 604 627 0.97
14 16 0.048 7.2 8.1 0.7 1 23 633 655 633 655 0.89
15 16 3.2e-07 4.8e-05 24.4 2.2 1 23 661 683 661 683 0.99
16 16 8.4e-06 0.0013 19.9 6.3 1 23 689 712 689 712 0.97

Sequence Information

Coding Sequence
atgtcaaaGCCAGAGTCAATTAGTACCTTAAGTGATCGTGAAGATGATATTGACAATTTGGATGGTTCTATGCTATGGTCTCAAGAGGAGCCACTTTCTTCTAAcgaaatattagaattatcggctcaagaaaaagaaaatagctCATTTGCTTTCTGTAGATTATGTGCTGGTCAAACCACTAATCcaatatttatctattctGAATTTGGAGAATCAATGAAACtggcacataaaataaatacatgctTAAGTGTTaagAAGACAGATCCATTACCGAAGCAGCTTTGTTTGACATGTGTTGAGAAAGTAAATTGGTATGACAAATTTGATGCACAATGCATTAAAGCAGAGGAAATCCTGTCAACAATGCTAAAGGAAAAGCagtcttttaatatttcaaatagagTCCTTTCTGACCAGCAATCCTGTCCCTTATGCATAAAGGGCTTCATGAATACATGTGAAGAGACTTTCCAGTATACGAAGGATAtggaattatatgaaaatataattttagatagCAGTGACGAGGAGAACATATTCAACAATGCCAAAGTCGATAAGGAAAGTGGTGGAACTTGTTCTATCACCTTACAATTCTTGGGAACCAGGcagaaatatctaaaatgtGGAGCATGCATGAATCTTTATCACACCGAGGAGACACTAAACGGTCATAAATGTAAGCCCAGTATGCAGAACACAACAAAACCGTATCAATGTCTTGTATGTGACAAGACATTTACTTTCGAGGAACGATTGAACTTTCACATGCAATTTCACAAAGGCGCGAAAGCATTGTATTGCGAGATCTGTAAGATAACGTTCGGTAAAGAGCTGAAGCTGTTCTACCACTATAAAAGACAACATTCTAAGGAGATTAGTGTCTCGTGTCTACAGTGTGGAAAATTATTCGAGAATCAGGAAGCGCTTCGAGTGCACGTTTGCGTCGACGGTAAAAATCGACCTCATATTTGCGAAGTGTGCAATAAAGGCTTTTTTGATGGCTACACTCTGAAGCGTCACGTAGTGACGCACCTGCCTGAGAAGCCTTACAAATGCTCGGAATGCTCAAAGAGCTTTACGCAGAAATCGAGATTGAACAAGCACGTCGCGAGCCACTGCATAGTTATCGAGAACAGTCAGACGGTCTGGAAATGCGTCCAGTGCGGTGAGGTATTCACCTCTTGCGATGATGCTGATATTCATTACAAGATAATACACGAGGACAAGATCACGCTGATCGAGGAACTGGTGGCAGTCAAGCTGTATCATTGCGAGTTTTGCAACAGCCATTTCACCAACGCGGACAACTTGAACATTCATCAAAAATGTCACGTTGTCGAAAAACCCTACACATGTAATACCTGCATGGCCACTTACAAATCATTCGCGGAAGCTGTTTTACACTGGAAGGAACATCCTAGACTGTTTAAAGTTCTCGTCGTCTTTTTATGCGACGTCTGCAACAAGGACATGAAGGAATTATCCCTGCTGTACAAGCATAAGCAAAACCGGCACGACCATGCATCCAGATTATCCGAGTCGGGCGATGCAAAATTCATCTGCGAACTCTGCGGGACTGTGTTCGACAAATGCGAGGATATACAGGATCATGGACGAGATCAATGTTCCAAGTTTCCCTGCGACATTTGTGGCAGCTTGCTGCCTACGGCGAACTCCTTGAATGCACATAAAAGGCGGCATAACGGATTAAGGCCATATGTCTGCAACATTTGTGGAAAGAGTTATACTCAGTCCAGCCACATGTGGACTCACAAGAGATTCCACATGGGCATCAAGCCTTACGCCTGCGAATATTGCGAGCAGCGTTTCACGATAAAGCCGGACTTGGCGGATCACATTAGGAAAAAGCATACGAGGGAGAGGCCGTTCAAGTGCGACGTGTGCAACAAGGCTTTCCTTACCGGATCCGTCTTTTATCAACACAGATTGATACACCGTGGTGATCGTAGATACAAGTGCCACTACTGCGAGAAGGCCTTCACCAGAACGGAAGCTTTGAACAACCACATCAAGATACACACTGGGGAAAAGCCGCATTCGTGCGACGTATGCGGCAGATGCTTCAGACAAAAGGGAGACATGAGGAAACACAGGCGCACAAAGCACGCTTCTGAACAAGACAAATCTTGA
Protein Sequence
MSKPESISTLSDREDDIDNLDGSMLWSQEEPLSSNEILELSAQEKENSSFAFCRLCAGQTTNPIFIYSEFGESMKLAHKINTCLSVKKTDPLPKQLCLTCVEKVNWYDKFDAQCIKAEEILSTMLKEKQSFNISNRVLSDQQSCPLCIKGFMNTCEETFQYTKDMELYENIILDSSDEENIFNNAKVDKESGGTCSITLQFLGTRQKYLKCGACMNLYHTEETLNGHKCKPSMQNTTKPYQCLVCDKTFTFEERLNFHMQFHKGAKALYCEICKITFGKELKLFYHYKRQHSKEISVSCLQCGKLFENQEALRVHVCVDGKNRPHICEVCNKGFFDGYTLKRHVVTHLPEKPYKCSECSKSFTQKSRLNKHVASHCIVIENSQTVWKCVQCGEVFTSCDDADIHYKIIHEDKITLIEELVAVKLYHCEFCNSHFTNADNLNIHQKCHVVEKPYTCNTCMATYKSFAEAVLHWKEHPRLFKVLVVFLCDVCNKDMKELSLLYKHKQNRHDHASRLSESGDAKFICELCGTVFDKCEDIQDHGRDQCSKFPCDICGSLLPTANSLNAHKRRHNGLRPYVCNICGKSYTQSSHMWTHKRFHMGIKPYACEYCEQRFTIKPDLADHIRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHSCDVCGRCFRQKGDMRKHRRTKHASEQDKS