Agra002452.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anoplolepis gracilipes
Gene Symbol
topi
Assembly
GCA_031304115.1
Location
JAPWJP010000294.1:1691369-1693690[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.31 56 5.7 2.8 1 23 246 268 246 268 0.86
2 16 0.074 13 7.7 1.1 2 23 275 297 274 297 0.95
3 16 0.00093 0.17 13.7 0.3 2 21 304 323 303 324 0.92
4 16 1.8e-05 0.0033 19.1 0.8 1 23 331 353 331 353 0.96
5 16 3e-06 0.00054 21.5 2.8 1 23 359 381 359 381 0.98
6 16 0.31 56 5.7 1.1 2 23 393 414 392 414 0.85
7 16 0.0045 0.81 11.5 5.4 1 23 430 452 430 452 0.98
8 16 0.017 3.1 9.7 0.5 1 23 458 480 458 480 0.96
9 16 0.026 4.6 9.1 1.3 1 23 490 513 490 513 0.94
10 16 0.11 21 7.1 0.0 1 21 527 547 527 548 0.92
11 16 0.0051 0.93 11.3 0.1 1 23 553 575 553 575 0.98
12 16 2.3e-06 0.00042 21.9 3.1 1 23 581 603 581 603 0.98
13 16 0.00015 0.027 16.2 0.4 1 23 609 632 609 632 0.97
14 16 0.056 10 8.1 0.7 1 23 638 660 638 660 0.89
15 16 3.7e-07 6.7e-05 24.4 2.2 1 23 666 688 666 688 0.99
16 16 7e-06 0.0013 20.4 4.9 1 23 694 717 694 717 0.96

Sequence Information

Coding Sequence
atgttcaaaGCAGAATCAATTAGTACACTAAGTGATCATGAAGATGATATTGATGATTTGGATGGCTCTATTATATGGTCCCAAGAAGAACCACTTTCTTCCAAcgaaatattagaattatcaactcaaaatgaaagagaagatAATTTAGCTGCTTTCTGTCGGTTGTGTGCTGGTCAAACCAATAatccaatatatatttattctgatCTCGGGGAATCAATGAAATTggcacataaaataaatacatgtttAAGTGTCaagATTAGAAAGACAGATCCATTACCAAAACAGCTTTGTTTGACCTGTATCGAGAAAGTAAATTGTTACGACAGGTTTGACACACAATGCATTAAAGCGGAAGAAATCCTCTTGACGATGCTAAAGGAGAGACAATCTTTCAATGCTTCTACTcatgaaaatcaaattttatctgaCCGACAGTCTTGTCCATTATGCATAGAGGGTTACATGAATACATGTGAAAACATGTCTCAGCATATAAAAGATGTAGAATTATACGAGAACGATATAATCTTAGAAAGTAGCGACGAggaaagtatatttaataatataaatgtcgaTAAGGAAAGTGGAAATCGTTCTATTATGTTACAATGCTTAGGAAATagtcagaaatatttaaaatgtggtGCATGCATGAATCTTTATCACACCAAGGAGACTCTAGATGGTCACAAGTGCAAGCCCAATATGCAGAACACAACGAAGCCATACAAGTGTCTTACGTGTGACACGACATTTAGTTTTGAGGAACGTTTGAACTTCCATACGCAATTTCACAGAAGCGCGAAAGCATTGTATTGCGAAATCTGCAAAATAACTTTCGGTAAAGAGTTGAAGCTATTTTATCACTATAAGAGATATCATTCCAAGGATATTAGCATTTCGTGTCTGCAGtgtggaaaattatttaagaatcagGAGGCGCTTCGTGTGCACGTTTGCGTGGACGGTAAGAATCGGCCACATATTTGCGAGGTTTGTAACAAAGGCTTTTCCGACGGCTATACCCTAAAGCGTCACATAGTGACCCACCTACCCGAGAAGCCTTACAAGTGCTCGCAATGTTCGAAGAGCTTTACACAGAAGTCGAGATTGAATAAGCATGTCGCAAGTCACTGCATCGTTATCGAAAACAATCAGATGGTCTGGAAATGCGTTCAATGTGGCGAAGTATTTATCTCTTGCGATGACGCTGATGCTCATTGCAAGATACATGAGAATAAAATCACATTGATCGAGCAGCTATCGATATCAAAATTGTATCATTGCGAATTCTGCAACAGTCATTTCATCGACATGGACAACCTGAAGACTCATCAGAATCGACACGTCGTCGAAAAACCGTACACGTGTAACAAGTGCGAAACTACATATAAATCATTCGCAGAAGCTATCTTACATTGGAAGGAACACCAGAGATTGTTCAAAGTTCTTGTCGTCTTTCTATGCGATGTCTGCAATAAGGACCTGAAGGAATTATCTCTGTTGTACAAACACAAGCAAAAGAGACATGATTATGTAGCCAGATTATCCGAATCCGGCGATGCAAAGTTCGTATGCGAACTTTGTGGAAATATATTCGACAAGAGTGAAGATATACAGGATCACGGACGAGATCAGTGTTCTAAATTTCCCTGTGATATTTGCGGCAGTCTATTGCCCACGGCAAATTCGTTAAATGCTCACAAAAGGCGCCACAACGGATTACGACCGTACGTCTGCAATATCTGTGGAAAAAGTTACACTCAGTCCAGTCACATGTGGACTCACAAGAGATTCCATATGGGTGTCAAGCCTTACGCTTGCGAATATTGCGATCAGCGTTTCACAATAAAGCCGGATTTGGCGGATCACACCAGGAAGAAGCATACGAGGGAGAGACCATTCAAGTGCGATGTCTGTAATAAGGCTTTTCTCACTGGATCTGTATTTTATCAGCATAGATTGATACACCGTGGCGATCGTAGATACAAGTGTCACTACTGCGAAAAGGCCTTTACCAGAACGGAGGCTTTAAATAATCACATTAAGATACATACCGGGGAAAAGCCACACGCGTGCGACGTGTGTGGCAGATGCTTCAGACAGAAAGGAGACATGAGGAAACATAGACGTACTCAACATAACTAA
Protein Sequence
MFKAESISTLSDHEDDIDDLDGSIIWSQEEPLSSNEILELSTQNEREDNLAAFCRLCAGQTNNPIYIYSDLGESMKLAHKINTCLSVKIRKTDPLPKQLCLTCIEKVNCYDRFDTQCIKAEEILLTMLKERQSFNASTHENQILSDRQSCPLCIEGYMNTCENMSQHIKDVELYENDIILESSDEESIFNNINVDKESGNRSIMLQCLGNSQKYLKCGACMNLYHTKETLDGHKCKPNMQNTTKPYKCLTCDTTFSFEERLNFHTQFHRSAKALYCEICKITFGKELKLFYHYKRYHSKDISISCLQCGKLFKNQEALRVHVCVDGKNRPHICEVCNKGFSDGYTLKRHIVTHLPEKPYKCSQCSKSFTQKSRLNKHVASHCIVIENNQMVWKCVQCGEVFISCDDADAHCKIHENKITLIEQLSISKLYHCEFCNSHFIDMDNLKTHQNRHVVEKPYTCNKCETTYKSFAEAILHWKEHQRLFKVLVVFLCDVCNKDLKELSLLYKHKQKRHDYVARLSESGDAKFVCELCGNIFDKSEDIQDHGRDQCSKFPCDICGSLLPTANSLNAHKRRHNGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACEYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTQHN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01354793;
90% Identity
iTF_00867636;
80% Identity
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