Basic Information

Insect: Tetramorium immigrans
Gene Symbol: topi
Assembly: GCA_011636585.1
Location: VBVO01000050.1:134079-136051[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.007 0.88 10.7 2.3 1 23 154 176 154 176 0.97

2 16 0.056 7 7.9 1.1 2 23 183 205 182 205 0.95

3 16 0.0029 0.37 11.9 0.3 2 21 212 231 211 232 0.92

4 16 0.00041 0.051 14.6 1.0 1 23 239 261 239 261 0.96

5 16 1.3e-06 0.00016 22.5 2.3 1 23 267 289 267 289 0.97

6 16 0.068 8.5 7.6 0.2 2 23 301 323 300 323 0.90

7 16 0.1 13 7.1 10.1 1 23 339 361 339 361 0.98

8 16 1.2 1.5e+02 3.7 0.5 1 23 367 389 367 389 0.93

9 16 0.28 35 5.7 1.1 1 23 399 422 399 422 0.92

10 16 0.86 1.1e+02 4.2 0.0 1 21 436 456 436 457 0.90

11 16 0.0059 0.74 11.0 0.0 1 23 462 484 462 484 0.98

12 16 1.7e-06 0.00022 22.1 3.1 1 23 490 512 490 512 0.98

13 16 0.00051 0.063 14.3 0.3 1 23 518 541 518 541 0.97

14 16 0.027 3.3 8.9 0.5 1 23 547 569 547 569 0.89

15 16 2.8e-07 3.5e-05 24.6 2.2 1 23 575 597 575 597 0.99

16 16 7.4e-06 0.00092 20.1 6.4 1 23 603 626 603 626 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.007	0.88	10.7	2.3	1	23	154	176	154	176	0.97
2	16	0.056	7	7.9	1.1	2	23	183	205	182	205	0.95
3	16	0.0029	0.37	11.9	0.3	2	21	212	231	211	232	0.92
4	16	0.00041	0.051	14.6	1.0	1	23	239	261	239	261	0.96
5	16	1.3e-06	0.00016	22.5	2.3	1	23	267	289	267	289	0.97
6	16	0.068	8.5	7.6	0.2	2	23	301	323	300	323	0.90
7	16	0.1	13	7.1	10.1	1	23	339	361	339	361	0.98
8	16	1.2	1.5e+02	3.7	0.5	1	23	367	389	367	389	0.93
9	16	0.28	35	5.7	1.1	1	23	399	422	399	422	0.92
10	16	0.86	1.1e+02	4.2	0.0	1	21	436	456	436	457	0.90
11	16	0.0059	0.74	11.0	0.0	1	23	462	484	462	484	0.98
12	16	1.7e-06	0.00022	22.1	3.1	1	23	490	512	490	512	0.98
13	16	0.00051	0.063	14.3	0.3	1	23	518	541	518	541	0.97
14	16	0.027	3.3	8.9	0.5	1	23	547	569	547	569	0.89
15	16	2.8e-07	3.5e-05	24.6	2.2	1	23	575	597	575	597	0.99
16	16	7.4e-06	0.00092	20.1	6.4	1	23	603	626	603	626	0.97

Sequence Information

Coding Sequence: atgtatatacacatacaaaaaatatatCTCTGTTTGACCTGCGTTGAGAAAGTGAACTGGTGCGACAAATTTGACACGCAGTGCATTAATGCGGAAGAAATTCTGTCAACAATATTAAAGGAAAAGCAATCTTTTAACATTTCCAATCAATTCCTTTCTGACCAACAGTCTTGTCCTTTGTGCGTAAACGGCTTCATGAACATGTGTGAAGAAACATTCCAGAATACGAAGGATATGGAATTATacgaaaatgatataattctaGAAAGCAGTGATGAGGAGAACGTATTTAATGACGCGAAGGTCGATAAGGAAAGCGGGAATCGTTCGATCACATTACAATGCTTAGGAAACAGACAGACGTATCTAAAATGCGGGGCATGCATGAATCTTTATCATACCAAGGAGACACTGGACAGTCACAAATGCAAGCCTAGTATACAGAGCACAACGAAACCGTACAAGTGTCTCATATGTGACAAGACATTTATGTTCGAAGAACGATTGAACTTTCACATGCGATTTCACAAAGGCTCGAAGGCATTATACTGCGAAATCTGTAAGATAACGTTCGGTAAAGAGCTGAAACTGTTCTACCACTATAAGAGGCAACATTCCAAGGAGATTAGCATTTCATGTCTACAGTGTGGAAAATTATTCGAGGATCAGAAGGCGCTTCGAACGCACGTTTGCGTCGATGGCAAAAATCGGCCTCACATTTGCGAAGTGTGCAACAAAGGCTTCTTCGACGGCTACACTCTGAAGCGTCACGTAGTGACGCACCTGCCGGAGAAGCCCTTCAAGTGCTCCGAGTGCTCGAAGAGCTTTACGCAGAAATCAAGATTGAACAAGCATGTCGCGAGCCACTGCATTGTTATCGAGAACAGCCAGACAGTCTGGAAGTGCATTCAGTGCGGCGAGGTGTTCACCACTTGCGACGATGCAGATATTCATTACAAGATAATACACGAGGACAAGGTCACGCTGATCGAAGAACTGACGACGTCCAAGCTGTATCACTGCGAATTCTGCAACAGCCATTTCACCAACGCGGACTGTCTGAAGGTTCATCAAAAGCATCACGTTGTCGAGAGACCCTACACGTGTAATACATGCATGACCACTTACAAATCGTTCGCGGAAGCCGTTTTACACTGGAAGGAGCATCCCAGACTATTTAAGGTACTCGTCGTCTTTCTATGCGACGTCTGCAACAAGGACATGAAGGAACTATCCCTGCTGTACAAGCACAAACAGAACAGGCACGAGCGTGCGTCCCGATCGTCCGAGTCGGGCGACGCCAAGTTTATCTGCGAGCTCTGCGGGAATTTGTTCGACAAGAACGAGGATATACAGGATCACGGACGAGATCAATGCTCCAAGTTTCCCTGCGACATTTGTGGCAACCTGCTGCCTACAGCGATCTCATTGAACGCGCATAAACGGCGGCATAATGGATTGCGGCCGTACGTCTGCAACATTTGCGGGAAGAGTTATACACAGTCGAGTCACATGTGGACTCACAAGAGATTCCACATGGGCATCAAGCCTTATGCTTGCGAGTTCTGCGACCAGCGTTTCACGATAAAGCCGGATCTGGCGGATCACGTCAGGAAGAAGCACACGAGGGAGAGACCGTTCAAGTGCGACGTGTGCGATAAGGCTTTCCTCACCGGGTCCGTGTTTTATCAGCACAGATTGATACACCGTGGCGATCGCAGATACAAGTGTCACTACTGCGAGAAGGCCTTCACCAGAACGGAGGCCTTGAACAACCATATCAAGATACATACCGGAGAAAAACCGCACTCGTGCGACGTGTGCGGCAGATGCTTCAGACAGAAAGGAGACATGAAGAAGCACAGGCGCACCAAGCATGCTTCCGAACAAGACAAAGCTTAA
Protein Sequence: MYIHIQKIYLCLTCVEKVNWCDKFDTQCINAEEILSTILKEKQSFNISNQFLSDQQSCPLCVNGFMNMCEETFQNTKDMELYENDIILESSDEENVFNDAKVDKESGNRSITLQCLGNRQTYLKCGACMNLYHTKETLDSHKCKPSIQSTTKPYKCLICDKTFMFEERLNFHMRFHKGSKALYCEICKITFGKELKLFYHYKRQHSKEISISCLQCGKLFEDQKALRTHVCVDGKNRPHICEVCNKGFFDGYTLKRHVVTHLPEKPFKCSECSKSFTQKSRLNKHVASHCIVIENSQTVWKCIQCGEVFTTCDDADIHYKIIHEDKVTLIEELTTSKLYHCEFCNSHFTNADCLKVHQKHHVVERPYTCNTCMTTYKSFAEAVLHWKEHPRLFKVLVVFLCDVCNKDMKELSLLYKHKQNRHERASRSSESGDAKFICELCGNLFDKNEDIQDHGRDQCSKFPCDICGNLLPTAISLNAHKRRHNGLRPYVCNICGKSYTQSSHMWTHKRFHMGIKPYACEFCDQRFTIKPDLADHVRKKHTRERPFKCDVCDKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHSCDVCGRCFRQKGDMKKHRRTKHASEQDKA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01354793;
90% Identity: iTF_00765849;
80% Identity: -