Waur001939.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Wasmannia auropunctata
Gene Symbol
topi
Assembly
GCA_000956235.1
Location
NW:1121065-1124333[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.023 1.7 8.7 4.4 1 23 243 265 243 265 0.96
2 16 0.087 6.4 6.9 1.1 2 23 272 294 271 294 0.95
3 16 0.64 47 4.2 0.8 2 21 302 321 301 322 0.90
4 16 0.00036 0.026 14.4 1.0 1 23 329 351 329 351 0.96
5 16 7.2e-07 5.3e-05 22.9 2.4 1 23 357 379 357 379 0.98
6 16 0.64 47 4.2 1.3 2 19 391 408 390 413 0.80
7 16 9.4e-05 0.0069 16.2 5.2 1 23 429 451 429 451 0.98
8 16 1.2 86 3.4 0.7 1 23 457 479 457 479 0.92
9 16 0.29 21 5.2 1.0 1 23 489 512 489 512 0.93
10 16 0.026 1.9 8.6 0.0 1 20 526 545 526 547 0.91
11 16 0.0034 0.25 11.3 0.1 1 23 552 574 552 574 0.98
12 16 1.5e-06 0.00011 21.9 3.1 1 23 580 602 580 602 0.98
13 16 9.7e-05 0.0071 16.2 0.3 1 23 608 631 608 631 0.97
14 16 0.037 2.7 8.1 0.7 1 23 637 659 637 659 0.89
15 16 2.4e-07 1.8e-05 24.4 2.2 1 23 665 687 665 687 0.99
16 16 6.5e-06 0.00048 19.9 6.3 1 23 693 716 693 716 0.97

Sequence Information

Coding Sequence
ATGTTACAAGCGGAGTCAATTAGCACGTTAAGTGACCGCGAAGATGATATTGACGATTTGGATGGTTCTATGATATGGTCCCAAGAGGAGCCACTTTCTTCCAACGAAATATTGGAATTGCCGGTGCAAGATGAAAAAGCAAAGAGTTCACTTGCTTTCTGTCGATTGTGTGCCGGTCAAACCGCCAAtccaatatatatctattctGAATTCGGAGAGTCAATGCAATTggcacataaaataaatacatgtcTAAGCATTAAGATTAAGAAGACGGACCCATTACCGAAGCAGCTTTGCTTGGCCTGCGTTGAGAAAGTGAACTGGTGCGACAAATTTGACATGCAATGCATTAAAGCGGAGGAAATCCTGTCGACGATGCTAAAGGAGAAGCAGTCTTTTAACATTTCCAATCAATTATTTTCCGATCAACAGTCCTGTCCCTTATGTGTAAAGGGCTTCATGAACATGTGCGAGGAGACAATCCAGAATACGAAGGACATGGAACTGTACGAGAATGATATAATCCTAGAGAGCAGCGACGAGGAGAACATGTTTAATGACGCGAAGGTCAATAAGGAAAGCGGGAGTCATTCCATCACATTGCAGTGCCTGGGAACTAGGcagagatatttaaaatgcgGAGCGTGCATGAATCTTTACCACACCGAGGAGACCCTGGACGGTCACAAGTGCAAGCCCAGTATACAGAACACGACAAAACCGTACTGTTGTCTCGTGTGCGACAAGACGTTTACGTTCGAGGAACGACTGAACTTCCACATGCGATTTCACAGGGGCGCGAAGGCGTTGTACTGCGAGGTCTGCAAGATAACGTTCGGCAAGGAGCTGAAGCTATTCTACCACTACAAGAGGCAACACTCTAATCACGAGATTAGCGTCTCGTGTCTGCAGTGCGGAAAGCTGTTCGAGTGTCAGGAGGCGCTCCGGGTGCACGTTTGCGTCGACGGTAAAATACGGCCGCACATTTGCGAGGTGTGCAACAAGGGCTTCTTCGACGGCTACACGCTGAAGCGTCACGTGGTGACGCACCTGCCCGAGAAGCCGTACAAGTGCACGGAGTGCTCGAAGAGCTTCACGCAGAAATCGCGATTGAACAAGCACGTCGCGAGCCACTGCATCGTCATCGAGAACAGCCAGACGGTCTGGAAGTGCGTCCAGTGCGGCGAGGCGTTCGCCTCCTGCGACGACGCGGATATTCATTGCAAGATAACACACGAGGACAGGGCCGCGCTGATCGAGGAGCTGCCGACGTCGAAGCTGTACCACTGCGAGTTCTGCAACAGCCACTTCACCAACGCGGACAACCTGAGGGCCCATCAAAAGCGTCACGTTGTCGAGAGACCGTACACGTGCAACACGTGCGTGGCCACTTGCAAATCGTTCGCGGAGGCTGTCTTGCACTGGAAGGAACATCCCAGACTGTTCAAGGTTCTCGTCGTCTTTCTGTGCGACGTCTGCAACAGGGACATGAAGGAACTGTCCCTGTTGTACAAGCACAGGCAAAACAGGCACGACCGTGCGCCCAGATTGTCCGAGTCCGGCGACGCGAGGTACGTCTGCGAGCTCTGCGGGAGCGTGTTCGAGAGGAGCGAGGATATACGGGGGCACGGACGGGATCAGTGCTCCAAGTTCCCCTGCGACATCTGCGGCAGCCTGCTGCCCACGGCGAACTCGTTGAACGCACACAAGAGGCGGCACAACGGCCTGCGGCCGTACGTCTGTAACATTTGCGGCAAGAGTTACACTCAGTCGAGCCACATGTGGACGCACAAGAGATTCCACATGGGCATCAAGCCGTACGCTTGCGAGTATTGCGACCAGCGTTTCACGATCAAGCCGGACCTGGCGGATCACGTCAGGAAGAAGCACACGAGGGAGAGGCCGTTCAAGTGCGACGTGTGCAACAAGGCTTTCCTGACCGGGTCCGTGTTCTACCAGCACCGACTGATACACCGCGGCGATCGCAGGTACAAGTGCCATTACTGCGAGAAGGCCTTCACCAGAACGGAGGCCTTGAACAACCACATCAAAATTCACACCGGCGAAAAGCCGCACTCGTGCGACGTGTGCGGCAGATGCTTCAGGCAAAAGGGCGATATGAGGAAACACAGACGCACCAAGCACGCCTCCGAGCAAGTTAAATCTTGA
Protein Sequence
MLQAESISTLSDREDDIDDLDGSMIWSQEEPLSSNEILELPVQDEKAKSSLAFCRLCAGQTANPIYIYSEFGESMQLAHKINTCLSIKIKKTDPLPKQLCLACVEKVNWCDKFDMQCIKAEEILSTMLKEKQSFNISNQLFSDQQSCPLCVKGFMNMCEETIQNTKDMELYENDIILESSDEENMFNDAKVNKESGSHSITLQCLGTRQRYLKCGACMNLYHTEETLDGHKCKPSIQNTTKPYCCLVCDKTFTFEERLNFHMRFHRGAKALYCEVCKITFGKELKLFYHYKRQHSNHEISVSCLQCGKLFECQEALRVHVCVDGKIRPHICEVCNKGFFDGYTLKRHVVTHLPEKPYKCTECSKSFTQKSRLNKHVASHCIVIENSQTVWKCVQCGEAFASCDDADIHCKITHEDRAALIEELPTSKLYHCEFCNSHFTNADNLRAHQKRHVVERPYTCNTCVATCKSFAEAVLHWKEHPRLFKVLVVFLCDVCNRDMKELSLLYKHRQNRHDRAPRLSESGDARYVCELCGSVFERSEDIRGHGRDQCSKFPCDICGSLLPTANSLNAHKRRHNGLRPYVCNICGKSYTQSSHMWTHKRFHMGIKPYACEYCDQRFTIKPDLADHVRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHSCDVCGRCFRQKGDMRKHRRTKHASEQVKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01354793;
90% Identity
iTF_00765849;
80% Identity
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