Pmex021230.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Polyergus mexicanus
Gene Symbol
topi
Assembly
GCA_030449975.1
Location
JAUDSZ010000011.1:8772037-8774336[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.3 2.3e+02 3.8 3.6 1 23 243 265 243 265 0.86
2 16 0.079 14 7.7 1.1 2 23 272 294 271 294 0.95
3 16 0.0026 0.46 12.3 0.3 2 21 301 320 300 321 0.93
4 16 1.9e-05 0.0034 19.1 0.8 1 23 328 350 328 350 0.96
5 16 9.5e-06 0.0017 20.0 2.4 1 23 356 378 356 378 0.98
6 16 1.5 2.7e+02 3.6 1.6 2 15 390 403 389 411 0.81
7 16 0.013 2.2 10.2 5.6 1 23 427 449 427 449 0.98
8 16 0.019 3.3 9.6 0.2 1 23 455 477 455 477 0.95
9 16 0.13 24 7.0 1.4 1 23 487 510 487 510 0.94
10 16 0.032 5.6 8.9 0.0 1 21 524 544 524 545 0.93
11 16 0.0036 0.63 11.9 0.1 1 23 550 572 550 572 0.98
12 16 2.5e-06 0.00043 21.9 3.1 1 23 578 600 578 600 0.98
13 16 0.00016 0.028 16.2 0.4 1 23 606 629 606 629 0.97
14 16 0.06 10 8.1 0.7 1 23 635 657 635 657 0.89
15 16 3.9e-07 6.9e-05 24.4 2.2 1 23 663 685 663 685 0.99
16 16 7.5e-06 0.0013 20.3 4.9 1 23 691 714 691 714 0.96

Sequence Information

Coding Sequence
atgtttaaagcAGAATCGATTAGTACACTAAGTGATCATGAAGATGATATTGATGATTTGGATGGCTCTATTGTGTGGTCTCAAGAAGAACCACTTTCTTCTAAtgaaatattagaattatCGACCCAAGATGAGAAAGAAGATAGTTTAGTTGCTTTCTGTCGATTGTGTGCTGGTCAAACTACTAATCCAATATATGTCTATTCTGAACTTGGCGAATCAATGAAATTGgcacataaaataaatacatgtcTAAGTAttaagATTAGAAAGACAGATCCATTACCGAAACAGCTTTGTTTGACTTGTATTGAGAAAGTAAATTGTTACAATAGGTTTGACACACAATGTATTAAAGCAGAGGAAATTCTCTTGACGATGCTAAAGGAGAGACAATCTTTCAATCatgaaaatcaaattttatctgACCGACAATCCTGCCCCTTATGTATAAAGGGTTACATGAACACATGTGAAAATATGTCCCAGCATGTGAAAGATATAGAATTATACGAGAACGATATAATCTTAGAAAGCAGTgacgaagaaaatatatttaataatataaacgtTGATAAGGAAAAAGGAAATTGTTCTATTATGTTACAATGCCTAGGAAATAGgcagaaatatttgaaatgcGGTGCGTGTATGAATCTTTATCACACCAAGGAGACTTTAGATGGTCACAAGTGCAAGCCCAGTATGCAAAGCACAACGAAGACGTACAAATGTTTTTCATGTGACACGACATTTAGTTTCGAGGAGCGTTTGAATTTCCACACGCAATTTCACAAAGGTGCGAAAGCGTTGTATTGCGAAATCTGCAAAATAACTTTCGGTAAAGAGTTGAAGTTATTCTATCACTACAAGAGATATCATTCCAAGGATATTAACATCTCGTGTCTGCAGTGTGGAAAATTATTCGAGAATCAAGAGATGCTCCGTATGCACATTTGCGTGGACGGTAAGAATCGGCCACATATTTGCGAGGTGTGTAACAAAGGCTTTTCCGATGGTTATACCCTGAAGCGTCACATAGTGACGCACCTGCCAGAGAAGCCTTACAAATGCTTGCAATGTTCGAAGAGCTTTACACAAAAGTCGAGATTGAATAAACATGTTGCGAGTCATTGCATTGTTATTGAAAACAATCAGACGGTCTGGAAATGTGTTCAATGCGGTGAAGTATTTATCTCTTGCGATGACGCCGATGGTCATTGCAAAATACACGAGGATAAGATCACGTTAATTGAGGAGTTATCGATATCGAAATTGTATCATTGTGAATTTTGCAACAGTCACTTTACCGAAGTGGACAATCTAAAGACTCATCAGAATAGACACGTCGTCGAGAAACCGTACATATGTAACATATGCAAAACTACATATAAATCATTCGCAGAGGCTATCTTACATTGGAAAGAACATCAAAGATTATTCAAAGTTCTCATCGTCTTTCTATGCGATATCTGCAACAAGGACATGAAGGAATTATCTCTATTGTACAAACACAAGCAAAAGAGACACGATTATGCAGCCAGATTATCCGAGTTCGGCAATGCAAAATTCGTATGCGAACTTTGCGGAAATATATTCGACAGAAGCAAGGATATACAGGATCATGGGCGAGATCAGTGTTCCAAATTTCCTTGTGATATTTGCGGTAATCTACTGCCCACGGCAAATTCGTTGAATGCTCATAAAAGGCGGCATAACGGACTGCGACCGTATGTCTGTAATATCTGTGGAAAGAGTTACACTCAGTCCAGTCACATGTGGACTCATAAGAGATTCCACATGGGCGTCAAGCCTTACGCTTGCGAATATTGCGATCAGCGTTTCACGATAAAGCCGGATTTGGCGGATCACACCAGGAAGAAGCATACGAGGGAGAGGCCATTCAAGTGCGATGTCTGTAATAAGGCTTTTCTCACCGGGTCCGTATTTTATCAGCATAGATTGATACACCGTGGTGATCGTAGATACAAGTGCCATTACTGTGAAAAGGCTTTTACCAGAACGGAAGCTTTAAATAATCACATTAAGATACATACTGGGGAAAAGCCTCATGCATGCGATGTCTGCGGTAGATGCTTCAGACAGAAAGGAGATATGAGGAAACATAGACGCACCCAACATAATTCTAGGCAGGATACATCTTGA
Protein Sequence
MFKAESISTLSDHEDDIDDLDGSIVWSQEEPLSSNEILELSTQDEKEDSLVAFCRLCAGQTTNPIYVYSELGESMKLAHKINTCLSIKIRKTDPLPKQLCLTCIEKVNCYNRFDTQCIKAEEILLTMLKERQSFNHENQILSDRQSCPLCIKGYMNTCENMSQHVKDIELYENDIILESSDEENIFNNINVDKEKGNCSIMLQCLGNRQKYLKCGACMNLYHTKETLDGHKCKPSMQSTTKTYKCFSCDTTFSFEERLNFHTQFHKGAKALYCEICKITFGKELKLFYHYKRYHSKDINISCLQCGKLFENQEMLRMHICVDGKNRPHICEVCNKGFSDGYTLKRHIVTHLPEKPYKCLQCSKSFTQKSRLNKHVASHCIVIENNQTVWKCVQCGEVFISCDDADGHCKIHEDKITLIEELSISKLYHCEFCNSHFTEVDNLKTHQNRHVVEKPYICNICKTTYKSFAEAILHWKEHQRLFKVLIVFLCDICNKDMKELSLLYKHKQKRHDYAARLSEFGNAKFVCELCGNIFDRSKDIQDHGRDQCSKFPCDICGNLLPTANSLNAHKRRHNGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACEYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTQHNSRQDTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01354793;
90% Identity
iTF_00867636;
80% Identity
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