Mrot001871.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megachile rotundata
Gene Symbol
ush
Assembly
GCA_000220905.1
Location
NW:1019768-1157921[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.0038 0.24 11.2 0.0 3 20 261 278 259 280 0.92
2 8 2.8e-05 0.0017 17.9 1.3 1 23 310 332 310 332 0.98
3 8 0.065 4 7.3 1.6 3 20 378 395 377 397 0.93
4 8 0.0097 0.6 9.9 4.4 2 21 612 631 611 632 0.94
5 8 0.045 2.8 7.8 0.0 3 20 660 677 658 679 0.91
6 8 0.011 0.68 9.7 0.0 2 23 718 739 717 739 0.95
7 8 0.014 0.87 9.4 1.5 1 23 745 767 745 767 0.98
8 8 0.063 3.9 7.3 0.5 3 21 860 878 859 879 0.92

Sequence Information

Coding Sequence
ATGTCACGTCGCAAGCAGAGCAACCCAAAACCACTGAAACGGGAGGATGAGGAATGGAGCGACTCGGAAAGGACACCTTCGGTGAGCAGCGGTGTGGAAGGTGGTGGATCGGCGGTTTCCAGCCCGATCGCGCCAGTTGTCGAAGAAGAATCGAGCCTGCCACCACCTCCGAGACTGAATCCTCCTCCGCCATCGGTTACGACCACGAATTCGACCGCCGAAGATATCAGACTGAGGCTCAGCGTGCTTTCCGAAGACGCTCGAAAACGGCTGGCTAGTTTCACCGAAGATATCGAGGTTGCTAGAAGCTTGCGAGATCGACATGCCACCCCGAGGCCAAATCAGACGCGAGAGTCGAGTCCCAAAGACACCGACGAGGAATCCAGCATGCTGGTGGTCAAGGAAGAGGATTGCCAACCGAGGTCGTCGTCTTCTTCAACGTCTTCGATCAGAAGACGAGAATCCGTCTGCAGAAGAGACTCGGAGGACTCCCAGAGGCGGTCCAACTCTGACGACCCGCCATCCGAGAAGAAGTTGAAACTGGACGACGAAGCAGCACCAAGACTGAGACTCAATGCTAGTCTGGCGACCGATCCTGCTCTTCGGCCTGCCGCCGTAGCCGCGCTCACTGTTAAACCGGAAAATACCTCGCCGCCGAATCCTGTGCCACCTTTACCAGCTGGTCTTCAAAATGCAATAGCATCGGGACGACTGTTCGTGTTACCGACCGACGGTAAAGAAACGATCACCGTAGAGCCTGCCAGACCAGCGGCACTGATATGTCCGCCCTGCGGCATCCGCTTCAGCTCAGCGAGCACTCTCGAAGCTCATCGCACCTTCTACTGCGCCCATCGGCCCCGGCTCGAGGAAGAGACGACGAACGAGGAGGATGAGGAGAAGTCGAGCAAGTTCGAAGCGAGGAAAGCGTACGCCTGTCCTCATTGTTCGTACAGCGCGGACAAGAAGGTGTCGTTGAATAGACACATGAGGATGCACGCAGCCTCTCCAGCGCCGCCCACGGTACCGACCGCGCCGACCACCGCCACAACTCCAGGAACCGGAGCGGCANNNNNNNNNNNNGGAGCGGCAACGACCTCCAACGGTTCTCTCAACGAAGAGGCAGAGAGATATTGCAGGAACTGCGACATCCGATTCAGCTCCTTGAAAACTTACAGAGCGCACAAGACTCACTACTGTAGCACCAGGCACGTGGTCAAAGATACACCACCGGCGGCCAGCGCGAGTTCCTCTTCGGTGAAGGCGTCTCCACCCACTAGTGCTAGTCCTGGCGAATCCCCGCCACCGCAGCCCTGTCTGGCACTGCCCACGAACCCTATCCTAATCGTACCGTACTCTCTGTTCCGAGGAGCCAGTGTCCTGGCTGCTCCGACTCTGCCCGCACCGGACACAGCGTGTTTCCTGCTTCCGAATGGTCATCTTCAGCCGATGACGAGGGGTCTCGCAGCCACAGCACAAAACACCGCAGAACCACCGCCGGTTCTTCGAGCCGCGAACAAGCCGACCACGCCTGTCTCCGTGGTAGCATCTTCCACGTCGCCGCCTGGATCGGCACCTCTCGATCTAAGTGTCAGGAAGTCACCGGCACACCAAGATGAGAAAGAGAACAGGGTGTCACCGGCACCGTCTTCTCTACCTCCACCACCGGGCAGTCCAAGATCCAGAGGAAGCGGTAGTCCCAGAGCGAGGTCCATCGGTTCCACTCCAACGACTGCTGGAACTGTTGCACCTCCACCACCGACAGAACTCGCTCTAAGACTGGCAGAGCTGCCACCTCCGCCGGTTCCTGGCGTCCTCGTGAAACAGGGCGTCTCGAGGTGCAAAGAATGCAACATCGTCTTCTGTCGACACGAGAACTTCGTCGCCCATAAGAAGCATTATTGCCAAGCAAGGGAAACGACGGTCAGCAGCAGTCCTCCGCCACCTGGGACACCTTCGCCTCCTCTGGTCCAACTGATCTGCGCTGCGTGTGGCATCAAGTTCGCCTCCATGGACAATTTGGTAGCTCATCAAGCATTTTACTGTCCTAAGAGGCCAGAACCCCAGGAACATCACTCGAGGTGTTCCAAGTGCAAGGCTATAATCGAGCCTGGAAGTACGCACGCCTGCTCCAGTGGGCCCACGGGTGGCTGGAGATGTCCTGTGTGTGGCGCGGTTAGCCCCACGGCTGGAGCTGCTCAGCGTCACATGGATGCTCATCAGGGTGTCAAGGCTTTCAGGTGTACCATCTGTCGATACAAAGGAAACACGTTGCGTGGAATGAGGACGCACATCAAAATGCATTTCGAGAAACGGGGAACGGACTTACAAGAAGAAAACTACATTACGTGCGTACTCGACGATGAGACGATTCTTCCGACTCCGGAACCAGCCCCAGCCACCACGCCTGAAGAGATACCTGCGGAGGTGCAAATGAACGGTAAGACGGAGGTGCGGAAGAGCCCACAACCACCTCCTCCACCGCCACCACCAACGGTGACCAGCAAAGTGAAACAGGAACGAGAAGATACGCCACCTCCGGAAGAAAGTTTGGATCCCAACAAGAGCGGCCCTCGTTATTGCAGGTCGTGCGACATCAGCTTCAATTACCTGAGCACGTTCATTGCCCACAAGAAGTTCTACTGCTCGAGCCACGCCGGCGAGGCGagcaataacaacaacaacaacaacaataataactCGAGCAGCCACGCTACCACGCCTCCTACCGGCAGGACCGAGGCGTCCGTACTTTAA
Protein Sequence
MSRRKQSNPKPLKREDEEWSDSERTPSVSSGVEGGGSAVSSPIAPVVEEESSLPPPPRLNPPPPSVTTTNSTAEDIRLRLSVLSEDARKRLASFTEDIEVARSLRDRHATPRPNQTRESSPKDTDEESSMLVVKEEDCQPRSSSSSTSSIRRRESVCRRDSEDSQRRSNSDDPPSEKKLKLDDEAAPRLRLNASLATDPALRPAAVAALTVKPENTSPPNPVPPLPAGLQNAIASGRLFVLPTDGKETITVEPARPAALICPPCGIRFSSASTLEAHRTFYCAHRPRLEEETTNEEDEEKSSKFEARKAYACPHCSYSADKKVSLNRHMRMHAASPAPPTVPTAPTTATTPGTGAAXXXXGAATTSNGSLNEEAERYCRNCDIRFSSLKTYRAHKTHYCSTRHVVKDTPPAASASSSSVKASPPTSASPGESPPPQPCLALPTNPILIVPYSLFRGASVLAAPTLPAPDTACFLLPNGHLQPMTRGLAATAQNTAEPPPVLRAANKPTTPVSVVASSTSPPGSAPLDLSVRKSPAHQDEKENRVSPAPSSLPPPPGSPRSRGSGSPRARSIGSTPTTAGTVAPPPPTELALRLAELPPPPVPGVLVKQGVSRCKECNIVFCRHENFVAHKKHYCQARETTVSSSPPPPGTPSPPLVQLICAACGIKFASMDNLVAHQAFYCPKRPEPQEHHSRCSKCKAIIEPGSTHACSSGPTGGWRCPVCGAVSPTAGAAQRHMDAHQGVKAFRCTICRYKGNTLRGMRTHIKMHFEKRGTDLQEENYITCVLDDETILPTPEPAPATTPEEIPAEVQMNGKTEVRKSPQPPPPPPPPTVTSKVKQEREDTPPPEESLDPNKSGPRYCRSCDISFNYLSTFIAHKKFYCSSHAGEASNNNNNNNNNNSSSHATTPPTGRTEASVL