Basic Information

Insect: Megachile leachella
Gene Symbol: ush
Assembly: GCA_963576845.1
Location: OY756252.1:379562-383101[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0056 0.84 11.1 0.0 3 20 275 292 273 294 0.92

2 8 4.1e-05 0.0062 17.9 1.3 1 23 324 346 324 346 0.98

3 8 0.095 14 7.3 1.6 3 20 385 402 384 404 0.93

4 8 0.014 2.1 9.9 4.4 2 21 619 638 618 639 0.94

5 8 0.066 9.9 7.8 0.0 3 20 667 684 665 686 0.91

6 8 0.016 2.4 9.7 0.0 2 23 725 746 724 746 0.95

7 8 0.021 3.1 9.4 1.5 1 23 752 774 752 774 0.98

8 8 0.093 14 7.3 0.5 3 21 867 885 866 886 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0056	0.84	11.1	0.0	3	20	275	292	273	294	0.92
2	8	4.1e-05	0.0062	17.9	1.3	1	23	324	346	324	346	0.98
3	8	0.095	14	7.3	1.6	3	20	385	402	384	404	0.93
4	8	0.014	2.1	9.9	4.4	2	21	619	638	618	639	0.94
5	8	0.066	9.9	7.8	0.0	3	20	667	684	665	686	0.91
6	8	0.016	2.4	9.7	0.0	2	23	725	746	724	746	0.95
7	8	0.021	3.1	9.4	1.5	1	23	752	774	752	774	0.98
8	8	0.093	14	7.3	0.5	3	21	867	885	866	886	0.92

Sequence Information

Coding Sequence: ATGGGAGCAGAGGGTACGCAAAGGCTGGCGTGGCGAGCGACCATTAGGGAGCCGAACGGCCATAGGGACGCATCGTTTAAACGGGAGGATGAGGAATGGAGCGACTCGGAAAGGACACCTTCGGTGAGCAGCGGTGTGGAAGGTGGTGGATCGGCGGTTTCCAGCCCGATCGCGCCAGCTGTCGAAGAAGAATCGAGCCTGCCACCACCTCCGAGACTGAATCCTCCTCCGCCATCGGTTACGACCACGAATTCGACCGCCGAGGATATCAGACTGAGGCTCAGCGTGCTTTCCGAAGACGCTCGGAAACGGCTGGCTAGTTTCACCGAAGATATCGAGGTTGCTAGAAGCTTGCGAGATCGACATGCCACCCCGAGGCCAAATCAGACGCGAGAGTCGAGTCCCAAAGACACCGACGAGGAATCCAGCATGCTGGTGGTCAAGGAAGAGGATTGCCAACCGAGGTCGTCGTCTTCTTCAACGTCTTCGATCAGAAGACGAGAGTCCGTGTGCAGAAGAGACTCGGAGGACTCCCAGAGGCGGTCCAACTCTGACGACCCGCCGTCCGAGAAGAAGTTGAAACTGGACGACGAAGCAGCACCAAGACTGAGACTCAATGCTAGTCTGGCGACCGATCCTGCCCTTCGGCCTGCCGCCGTAGCCGCGCTCACTGTTAAACCGGAAAATACCTCGCCGCCGAATCCTGTGCCACCTTTACCAGCTGGTCTTCAAAATGCAATAGCATCGGGTCGACTGTTCGTATTACCGACCGACGGTAAAGAAACGATCACCGTGGAGCCTGCCAGACCAGCGGCACTGATATGTCCACCCTGCGGCATCCGCTTCAGCTCAGCGAGCACTCTCGAGGCTCATCGCACCTTCTACTGCGCCCATCGACCCCGACTCGAGGAAGAGACGACGAACGAGGAGGACGAGGAGAAGTCGAGCAAGTTCGAAGCGAGGAAAGCGTACGCCTGTCCTCATTGTTCGTACAGCGCGGACAAGAAAGTGTCGTTGAACAGACACATGAGGATGCACGCAGCCTCTCCAGCACCACCCACGGTACCGACAGCGCCGACCACCGCCACGACTCCAGGAACCGGAGCGGCAACGACCTCCAACGGTTCTCTCAACGAAGAGGCAGAGAGATATTGCAGGAACTGCGACATCCGATTCAGCTCCTTGAAGACTTACAGAGCGCACAAGACTCACTACTGTAGCACCAGGCACGTGGTCAAAGATACACCACCTGCGGCCAGCGCGAGTTCCTCTTCGGTGAAGGCGTCTCCACCTACTAGTGCTAGTCCTGGCGAATCCCCGCCACCGCAACCCTGCCTGGCACTACCCACGAACCCTATCCTAATCGTACCGTACTCTCTTTTCCGAGGAGCCAGTGTCCTGGCCGCTCCGACTCTGCCCGCACCGGACACCGCGTGTTTCCTGCTTCCGAATGGTCATCTTCAGCCGATGACGAGGGGTCTCGCAGCCGCGGCACAAAACACCGTAGAACCACCGCCGGTTCTTCGAGCCGCGAACAAGCCGACCACGCCTGTCTCCGTAGTAGCATCGTCCACGTCGCCGCCTGGTTCGGCACCTCTCGATCTAAGTGTCAGGAAGTCGCCGGCACACCAAGATGAGAAAGAGAACAGGGTGTCACCGGCACCGTCTTCTCTACCTCCACCACCGGGCAGTCCGAGATCCAGAGGAAGCGGTAGTCCCAGAGCGAGGTCCATCGGTTCCACTCCAACGACTGCTGGAACTGTTGCACCTCCACCACCGACAGAACTCGCTCTAAGACTGGCAGAGCTGCCGCCTCCGCCGGTTCCTGGTGTCCTCGTGAAACAGGGCGTCTCGAGGTGCAAAGAATGCAACATCGTCTTCTGTCGACACGAGAACTTCGTCGCCCATAAGAAGCATTATTGCCAAGCAAGGGAGACGACGGTAAGCAGCAGTCCTCCGCCACCTGGGACACCTTCGCCTCCTTTGGTCCAACTGATCTGTGCTGCGTGCGGCATCAAGTTCGCCTCCATGGATAATTTGGTAGCTCATCAAGCATTTTACTGTCCTAAGAGGCCAGAACCCCAAGAACATCACTCGAGGTGCTCCAAGTGCAAGGCTATAATCGAGCCTGGAAGTACGCACGCCTGCTCCAGTGGACCCACGGGGGGCTGGAGATGTCCCGTGTGTGGCGCGGTTAGCCCCACGGCTGGAGCTGCTCAGCGTCACATGGATGCTCATCAGGGTGTCAAGGCTTTCAGGTGTACCATCTGTCGGTACAAAGGAAACACGTTGCGTGGAATGAGGACGCACATAAAGATGCATTTCGAGAAACGGGGAACGGACCTACAAGAAGAAAACTACATTACGTGCGTACTCGACGACGAGACGATTCTTCCGACTCCGGAACCAGCCCCAGCCACCACGCCTGAAGAGATACCTGCGGAGGTGCAAATGAACGGTAAGACGGAGGTGCGGAAGAGCCCACAACCACCTCCTCCACCGCCGCCACCAACGGTGACCAGTAAAGTGAAACAGGAACGAGAAGACACGCCACCTCCGGAAGAAAGTTTGGATCCCAACAAGAGCGGCCCTCGTTATTGCAGGTCGTGCGACATCAGCTTCAATTACCTGAGCACGTTCATTGCCCACAAGAAGTTCTACTGCTCGAGCCACGCCGGCGAGGCGAgcaataacaacaacaacaacaacaataataactCGAGCAGCCACGCTACAACGCCTCCTACCGGCAGGACCGAGGCGTCCGTACTATAA
Protein Sequence: MGAEGTQRLAWRATIREPNGHRDASFKREDEEWSDSERTPSVSSGVEGGGSAVSSPIAPAVEEESSLPPPPRLNPPPPSVTTTNSTAEDIRLRLSVLSEDARKRLASFTEDIEVARSLRDRHATPRPNQTRESSPKDTDEESSMLVVKEEDCQPRSSSSSTSSIRRRESVCRRDSEDSQRRSNSDDPPSEKKLKLDDEAAPRLRLNASLATDPALRPAAVAALTVKPENTSPPNPVPPLPAGLQNAIASGRLFVLPTDGKETITVEPARPAALICPPCGIRFSSASTLEAHRTFYCAHRPRLEEETTNEEDEEKSSKFEARKAYACPHCSYSADKKVSLNRHMRMHAASPAPPTVPTAPTTATTPGTGAATTSNGSLNEEAERYCRNCDIRFSSLKTYRAHKTHYCSTRHVVKDTPPAASASSSSVKASPPTSASPGESPPPQPCLALPTNPILIVPYSLFRGASVLAAPTLPAPDTACFLLPNGHLQPMTRGLAAAAQNTVEPPPVLRAANKPTTPVSVVASSTSPPGSAPLDLSVRKSPAHQDEKENRVSPAPSSLPPPPGSPRSRGSGSPRARSIGSTPTTAGTVAPPPPTELALRLAELPPPPVPGVLVKQGVSRCKECNIVFCRHENFVAHKKHYCQARETTVSSSPPPPGTPSPPLVQLICAACGIKFASMDNLVAHQAFYCPKRPEPQEHHSRCSKCKAIIEPGSTHACSSGPTGGWRCPVCGAVSPTAGAAQRHMDAHQGVKAFRCTICRYKGNTLRGMRTHIKMHFEKRGTDLQEENYITCVLDDETILPTPEPAPATTPEEIPAEVQMNGKTEVRKSPQPPPPPPPPTVTSKVKQEREDTPPPEESLDPNKSGPRYCRSCDISFNYLSTFIAHKKFYCSSHAGEASNNNNNNNNNNSSSHATTPPTGRTEASVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01255959;
90% Identity: iTF_00964084;
80% Identity: -