Basic Information

Insect: Bombus sibiricus
Gene Symbol: ush
Assembly: GCA_014737505.1
Location: JACXIM010000026.1:1439492-1640094[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0058 0.65 10.9 0.1 3 20 261 278 259 280 0.92

2 8 3.6e-05 0.0041 17.9 1.3 1 23 310 332 310 332 0.98

3 8 0.083 9.3 7.3 1.6 3 20 371 388 370 390 0.93

4 8 0.012 1.4 9.9 4.4 2 21 606 625 605 626 0.94

5 8 0.058 6.5 7.8 0.0 3 20 654 671 652 673 0.91

6 8 0.014 1.6 9.7 0.0 2 23 712 733 711 733 0.95

7 8 0.018 2 9.4 1.5 1 23 739 761 739 761 0.98

8 8 0.081 9.1 7.3 0.5 3 21 856 874 855 875 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0058	0.65	10.9	0.1	3	20	261	278	259	280	0.92
2	8	3.6e-05	0.0041	17.9	1.3	1	23	310	332	310	332	0.98
3	8	0.083	9.3	7.3	1.6	3	20	371	388	370	390	0.93
4	8	0.012	1.4	9.9	4.4	2	21	606	625	605	626	0.94
5	8	0.058	6.5	7.8	0.0	3	20	654	671	652	673	0.91
6	8	0.014	1.6	9.7	0.0	2	23	712	733	711	733	0.95
7	8	0.018	2	9.4	1.5	1	23	739	761	739	761	0.98
8	8	0.081	9.1	7.3	0.5	3	21	856	874	855	875	0.92

Sequence Information

Coding Sequence: ATGTCACGCCGCAAGCAGAGCAATCCAAAACCACTGAAACGGGAGGATGAGGAATGGAGCGACTCGGAGAAGACACCATCGGTGAGCAGCGGAGTGGAAGGCGGTGGATCGGCGGTTTCCAGCCCGATCGCGCCGGTTGTCGAGGAGGAATCGAGTTTACCGCCACCACCGAGACTGAATCCCCCTTCCTCGTCCGTTGCGATCGCGAATTCGGCCGCTGAGGATATCAGATTGAGGCTCAGCGTGCTCCCTGAAGACGCTCGGAAACGACTGGCTAGTCTTACCGAAGATATCGAGGTTGCAAGAAGCTTAAGAGATCGACATGTCACCCCGAGATCCAATCAGACGCGAGAATCGAGTCCGAAAGACACGGACGAGGAGTCCAATCTGGTCATGGTCAAAGAAGAGGATTGTCAGCCGAGATCGTCGTCCTCTTCGTCGTCCTCGACAAGAAGACGGGAATCCATGTGCAGGCGAGACTCGGAGGACTCGTCGAGACGATCGAATACGGACGATCCACCGACCGAGAAAAAGTTGAAACTCGACGATGAAGCTGCACCAAGACTGAGACTCAATCCTAGTCTGGCGACGGATCCAGCTCTTCGGCCCGCCGCCGTAGTCGCGCTCACCGTCAAACCGGAAAATACCTCGCCACCGAATCCTGTGCCACCCCTTCCGGCTGGACTTCAAAATGCAATCGCCTCAGGTCGTTTGTTCGTACTTCCAACCGATGGCAAGGAGACGATCACTGTGGAGCCAGCCAGGCCAGCACCTCTCTTCTGTCCTCCATGCGGCATCCGTTTTAGCTCAGCGAGCACCCTCGAAGCGCATCGCACTTTCTACTGCGCTCATCGTCCCCGACTCGAGGAAGACACCGCCAACGAAGAGGACGAGGAAAAGTCCAACAAATTCGAAGTGAGAAAAGCGTATGCCTGCCCTCACTGCTCGTACAGCGCGGACAAGAAGGTCTCGTTGAACAGACACATGAGAATGCATGCTGCATCTCCTGCACCACCCACGATACCAACCGCTCCGACTACAGCTACTACTCCAGGAAGTGGTGCGGCAAATGCCTCGAATGGCTCCTTGAACGAAGAGGCGGAGAGATATTGCAGAAACTGCGATATTCGATTCAGCTCCCTGAAGACTTATAGAGCGCACAAGACGCATTATTGTAGTACTAGGCACGTGGTCAAAGATACGCCACCAGCAGCTACGGTAGCTTCCTCGTCGGTGAAAGCTTCGCCACCGACGAGCGCGAGTCCCGGTGAATCGCCGCCTCCGCAACCTTGTCTGGCGCTACCTACAAATCCTATTTTGATTGTACCGTACTCTTTGTTCCGAGGTGCTAGTGTCTTGGCAGCACCCACTTTGCCCGCGCCTGATACTGCGTGCTTTCTTCTTCCAAATGGTCATCTTCAACCGATGACAAGAGGTCTGGCTACCACAGCGCAGAACACCGTGGTCGAACCTTCACCGGTTCTCCGAGCAGCGAACAAACCAACGACACCAGCGTCCGTCGTGGCATCGTCGACGTCGCCATCAGGTTCAGCGCCACTCGATTTGAGCGTTAGAAAGTCACCAGCTCATCAAGATGAAAAAGAGAACAGGGTATCGCCGGCACCCTCTTCTCTACCTCCACCACCTGGTAGTCCTAGGTCAAGAGGAAGCGGAAGTCCTAGAGCAAGGTCCATTGGTTCTGCTCCTACGGCTACTGGAACCGTTGCACCTCCTCCGCCGACGGAACTCGCTCTCAGACTGGCTGAACTTCCACCACCCCCTGTTCCTGGGGTTCTTGTGAAGCAAGGTGTCTCGAGATGCAAAGAATGTAATATCGTGTTCTGTCGGCATGAAAACTTCGTCGCACATAAAAAGCATTATTGTCAGGCAAGAGAGACAACGGTCAGCAATAGTCCTCCACCACCTGGAACACCCTCGCCTCCTTTGGTGCAATTAATCTGTGCCGCGTGTGGTATCAAGTTCGCATCTATGGATAATCTGGTAGCTCATCAAGCGTTTTACTGTCCCAAAAGGCCAGAACCTCAGGAACATCATTCGCGATGCTCCAAGTGCAAAACTATAATTGAACCTGGAGGCACCCATACCTGTAGCAGCGGACCGACTGGAGGTTGGAGATGTCCCGTTTGTGGTGCGGTTAGTCCAACAGCCGGAGCAGCTCAGCGTCATATGGATGCTCATCAGGGTGTCAAGGCTTTCAGGTGTACGATCTGTCGTTACAAAGGAAATACATTACGGGGAATGAGAACGCACATCAAAATGCACTTTGAGAAACGTGGAACCGATCTACAGGAAGAAAATTACATAACGTGCGTACTCGACGACGAAACAGTTCTGCCGACTCCAGAACCGGCTCCAGCTACGACTCCTGAAGAAATCCCTGGCGAGGTGCAAGTAAATGGGAAAACCGAAGTTCGGAAGAGTCCTCAGCCACCTCCACCGCCACCACCGCCACCACCGACGGTAACCAACAAGGTGAAGCAAGAACGCGAGGACACTCCACCTCCCGAAGAAAGTTTGGATCCGAACAAAAGCGGTCCGCGTTACTGCAGGTCGTGCGACATTAGCTTCAATTACTTGAGCACGTTCATTGCTCACAAGAAGTTCTATTGCTCGAGTCATGCCGGCGAGGCGAGCAACAACAATAATAATAATAATAATAATAATTCGAGCAGTCACGCGACGACGCCTCCCAGCAACAGGACCGAGGCGTCAGTACTTTAA
Protein Sequence: MSRRKQSNPKPLKREDEEWSDSEKTPSVSSGVEGGGSAVSSPIAPVVEEESSLPPPPRLNPPSSSVAIANSAAEDIRLRLSVLPEDARKRLASLTEDIEVARSLRDRHVTPRSNQTRESSPKDTDEESNLVMVKEEDCQPRSSSSSSSSTRRRESMCRRDSEDSSRRSNTDDPPTEKKLKLDDEAAPRLRLNPSLATDPALRPAAVVALTVKPENTSPPNPVPPLPAGLQNAIASGRLFVLPTDGKETITVEPARPAPLFCPPCGIRFSSASTLEAHRTFYCAHRPRLEEDTANEEDEEKSNKFEVRKAYACPHCSYSADKKVSLNRHMRMHAASPAPPTIPTAPTTATTPGSGAANASNGSLNEEAERYCRNCDIRFSSLKTYRAHKTHYCSTRHVVKDTPPAATVASSSVKASPPTSASPGESPPPQPCLALPTNPILIVPYSLFRGASVLAAPTLPAPDTACFLLPNGHLQPMTRGLATTAQNTVVEPSPVLRAANKPTTPASVVASSTSPSGSAPLDLSVRKSPAHQDEKENRVSPAPSSLPPPPGSPRSRGSGSPRARSIGSAPTATGTVAPPPPTELALRLAELPPPPVPGVLVKQGVSRCKECNIVFCRHENFVAHKKHYCQARETTVSNSPPPPGTPSPPLVQLICAACGIKFASMDNLVAHQAFYCPKRPEPQEHHSRCSKCKTIIEPGGTHTCSSGPTGGWRCPVCGAVSPTAGAAQRHMDAHQGVKAFRCTICRYKGNTLRGMRTHIKMHFEKRGTDLQEENYITCVLDDETVLPTPEPAPATTPEEIPGEVQVNGKTEVRKSPQPPPPPPPPPPTVTNKVKQEREDTPPPEESLDPNKSGPRYCRSCDISFNYLSTFIAHKKFYCSSHAGEASNNNNNNNNNNSSSHATTPPSNRTEASVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00983220;
90% Identity: iTF_00964084;
80% Identity: iTF_00231580;