Basic Information

Insect: Megachile ligniseca
Gene Symbol: ush
Assembly: GCA_945859565.1
Location: CAMAOB010000017.1:9827-13373[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0052 0.54 11.2 0.0 3 20 269 286 267 288 0.92

2 8 3.9e-05 0.004 17.9 1.3 1 23 318 340 318 340 0.98

3 8 0.088 9.1 7.3 1.6 3 20 379 396 378 398 0.93

4 8 0.013 1.4 9.9 4.4 2 21 613 632 612 633 0.94

5 8 0.062 6.4 7.8 0.0 3 20 661 678 659 680 0.91

6 8 0.015 1.6 9.7 0.0 2 23 719 740 718 740 0.95

7 8 0.019 2 9.4 1.5 1 23 746 768 746 768 0.98

8 8 0.086 8.9 7.3 0.5 3 21 861 879 860 880 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0052	0.54	11.2	0.0	3	20	269	286	267	288	0.92
2	8	3.9e-05	0.004	17.9	1.3	1	23	318	340	318	340	0.98
3	8	0.088	9.1	7.3	1.6	3	20	379	396	378	398	0.93
4	8	0.013	1.4	9.9	4.4	2	21	613	632	612	633	0.94
5	8	0.062	6.4	7.8	0.0	3	20	661	678	659	680	0.91
6	8	0.015	1.6	9.7	0.0	2	23	719	740	718	740	0.95
7	8	0.019	2	9.4	1.5	1	23	746	768	746	768	0.98
8	8	0.086	8.9	7.3	0.5	3	21	861	879	860	880	0.92

Sequence Information

Coding Sequence: ATGGGAGCAGAGGGTACGCTGGCGTGGCGAGCGACCATTAGGGAGCCGAACGGCCATAGGGACGCATCGTTTAGACGGGAGGATGAGGAATGGAGCGACTCGGAAAGAACACCTTCGGTGAGCAGCGGAGTGGAGGGTGGTGGATCGGCGGTTTCCAGCCCGATCGCGCCAGTTGTCGAAGAAGAATCGAGCCTGCCACCACCTCCGAGACTGAATCCTCCGCCATCGAGCACGAATTCGACCGCTGACGATATCAGACTGAGGCTCAGCGTGCTTTCCGAAGACGCTCGGAAACGGCTGGCTAGTTTCACCGAAGATATCGAGGTTGCTAGAAGCTTGCGAGATCGACATGCCACCCCGAGGCCAAATCAGACGCGAGAGTCGAGTCCCAAAGACACCGACGAGGAATCCATGCTGGTGGTCAAGGAAGAGGATTGCCAACCGCGGTCGTCGTCTTCTTCAACGTCTTCGATCAGAAGGCGGGAGTCCGTGTGCAGAAGAGACTCGGAGGATTCCCAGAGGCGGTCCAACTCTGACGACCCGCCGTCCGAGAAGAAGTTGAAACTGGACGACGAAGCAGCACCAAGACTGAGACTCAATGCTAGTCTGGCGACCGATCCTGCTCTTCGGCCTGCCGCCGTAGCCGCGCTCACTGTTAAACCGGAAAATACCTCGCCGCCGAATCCTGTGCCACCTTTGCCAGCTGGTCTTCAAAATGCAATAGCATCGGGTCGACTGTTCGTATTACCGACCGACGGTAAAGAAACGATCACCGTGGAACCTGCCAGACCAGCGGCACTGATATGTCCGCCCTGCGGCATCCGCTTCAGCTCAGCGAGCACTCTCGAAGCTCATCGCACCTTCTACTGCGCCCATCGGCCCCGGCTCGAGGAAGACACGACGAACGAGGAGGACGAGGAGAAGTCGAGCAAGTTCGAAGCAAGGAAAGCGTACGCCTGTCCTCATTGTTCGTACAGCGCGGACAAGAAGGTGTCGTTGAACAGACACATGAGGATGCATGCGGCTTCTCCAGCACCGCCCACGGTACCAACCGCGCCGACCACCGCCACAACTCCAGGAACCGGAGCGGCGACGACCTCCAACGGTTCTCTGAACGAAGAGGCAGAGAGATATTGCAGGAACTGCGACATCAGATTCAGCTCCCTGAAGACTTACAGAGCGCACAAGACTCACTACTGCAGCACCAGGCACGTGGTCAAAGACACACCACCGGCGGCCAGCGCGAGTTCCTCTTCGGCGAAGGCCTCTCCACCTACTAGTGCTAGTCCTGGCGAATCCCCGCCACCGCAGCCCTGTCTGGCACTGCCCACGAACCCTATTCTGATCGTACCGTACTCTCTGTTCCGAGGAGCCAGTGTCTTGGCCGCTCCGACTCTGCCCGCACCGGACACCGCGTGTTTCCTGCTTCCGAATGGTCATCTTCAGCCGATGACGCGGGGTCTGGCAGCCGCAGCACAAAACACCGCAGAGCCACCGCCGGTTCTTCGAGCCGCGAACAAGCCGACCACGCCTGTCTCCGTGGTAGCATCGTCCACGTCGCCACCTGGTTCGGCACCGCTCGATTTAAGTGTTCGGAAATCACCGGCACACCAAGATGAGAAGGAGAACAGGGTGTCACCGGCACCGTCTTCTCTACCTCCGCCACCGGGTAGTCCGAGATCCAGAGGAAGCGGTAGTCCCAGAGCGAGGTCCATCGGTTCCACTCCAACGGCAGCTGGAACTGTTGCACCTCCACCACCGACAGAACTCGCTCTGAGACTGGCCGAGTTGCCACCTCCGCCGGTTCCTGGCGTCCTCGTGAAACAGGGCGTCTCGAGGTGCAAAGAATGCAACATCGTCTTCTGTCGACACGAGAACTTCGTCGCCCATAAGAAGCATTATTGCCAGGCAAGGGAGACGACGGTCAGCAGCAGTCCTCCGCCACCTGGGACACCTTCGCCTCCTCTGGTCCAGCTGATCTGCGCTGCGTGTGGCATCAAGTTCGCTTCCATGGATAATTTGGTAGCTCATCAAGCGTTTTACTGCCCTAAGAGGCCGGAACCCCAGGAACATCACTCGAGGTGTTCCAAGTGCAAGGCTATAATCGAGCCTGGAAGTACGCACGCCTGCTCCAGTGGACCCACGGGTGGCTGGAGATGTCCCGTGTGCGGCGCGGTTAGCCCCACGGCTGGAGCTGCTCAGCGTCACATGGATGCTCACCAGGGTGTCAAGGCTTTCAGGTGTACCATCTGTCGGTACAAAGGGAACACGTTGCGTGGAATGAGGACGCACATCAAGATGCATTTCGAGAAACGAGGAACGGACCTGCAAGAAGAAAACTACATTACGTGCGTACTCGACGACGAAACGATTCTTCCGACTCCGGAACCAGCCCCAGCCACCACACCTGAAGAGATACCTGCGGAGGTGCAAATGAACGGTAAGACGGAGGTGCGGAAGAGCCCACAACCACCTCCTCCACCTCCACCACCAACGGTGACCAGCAAAGTGAAACAGGAACGAGAAGATACGCCACCTCCGGAAGAAAGTTTGGATCCCAACAAGAGCGGCCCTCGTTATTGCAGGTCCTGCGACATCAGCTTCAATTACCTTAGTACGTTCATTGCCCACAAGAAGTTCTACTGCTCGAGCCACGCCGGCGAGGCGAGCAACAACAACAACAACAATAATAACTCGAGCAGCCACGCTACAACGCCTCCCACCGGCAGGACCGAGGCGTCCGTGCTTTAA
Protein Sequence: MGAEGTLAWRATIREPNGHRDASFRREDEEWSDSERTPSVSSGVEGGGSAVSSPIAPVVEEESSLPPPPRLNPPPSSTNSTADDIRLRLSVLSEDARKRLASFTEDIEVARSLRDRHATPRPNQTRESSPKDTDEESMLVVKEEDCQPRSSSSSTSSIRRRESVCRRDSEDSQRRSNSDDPPSEKKLKLDDEAAPRLRLNASLATDPALRPAAVAALTVKPENTSPPNPVPPLPAGLQNAIASGRLFVLPTDGKETITVEPARPAALICPPCGIRFSSASTLEAHRTFYCAHRPRLEEDTTNEEDEEKSSKFEARKAYACPHCSYSADKKVSLNRHMRMHAASPAPPTVPTAPTTATTPGTGAATTSNGSLNEEAERYCRNCDIRFSSLKTYRAHKTHYCSTRHVVKDTPPAASASSSSAKASPPTSASPGESPPPQPCLALPTNPILIVPYSLFRGASVLAAPTLPAPDTACFLLPNGHLQPMTRGLAAAAQNTAEPPPVLRAANKPTTPVSVVASSTSPPGSAPLDLSVRKSPAHQDEKENRVSPAPSSLPPPPGSPRSRGSGSPRARSIGSTPTAAGTVAPPPPTELALRLAELPPPPVPGVLVKQGVSRCKECNIVFCRHENFVAHKKHYCQARETTVSSSPPPPGTPSPPLVQLICAACGIKFASMDNLVAHQAFYCPKRPEPQEHHSRCSKCKAIIEPGSTHACSSGPTGGWRCPVCGAVSPTAGAAQRHMDAHQGVKAFRCTICRYKGNTLRGMRTHIKMHFEKRGTDLQEENYITCVLDDETILPTPEPAPATTPEEIPAEVQMNGKTEVRKSPQPPPPPPPPTVTSKVKQEREDTPPPEESLDPNKSGPRYCRSCDISFNYLSTFIAHKKFYCSSHAGEASNNNNNNNNSSSHATTPPTGRTEASVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01255959;
90% Identity: iTF_00964084;
80% Identity: -