Fvar003390.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Frieseomelitta varia
Gene Symbol
-
Assembly
GCA_011392965.1
Location
WNWW01001023.1:120689-123768[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 7.4 4.6e+02 0.8 0.2 2 19 328 345 327 347 0.83
2 16 0.0068 0.42 10.4 3.2 2 20 385 403 384 405 0.94
3 16 0.043 2.6 7.9 3.5 2 23 446 468 446 468 0.95
4 16 0.011 0.66 9.8 0.1 1 23 474 496 474 496 0.96
5 16 2.5e-06 0.00015 21.2 3.4 1 23 502 524 502 524 0.96
6 16 0.0002 0.012 15.2 2.0 1 23 533 555 533 555 0.96
7 16 1.6e-05 0.001 18.7 1.8 1 23 561 583 561 583 0.98
8 16 7.9e-06 0.00049 19.6 1.0 1 23 588 610 588 610 0.97
9 16 0.0022 0.14 11.9 7.8 1 23 617 639 617 639 0.99
10 16 0.0011 0.069 12.9 0.5 2 23 658 679 657 679 0.97
11 16 0.00049 0.031 14.0 0.3 3 23 688 709 686 709 0.96
12 16 0.0005 0.031 13.9 0.5 1 23 715 737 715 737 0.98
13 16 2.5e-07 1.6e-05 24.3 1.3 1 23 743 765 743 765 0.98
14 16 3.7e-06 0.00023 20.6 0.8 1 23 771 793 771 793 0.98
15 16 2e-06 0.00012 21.5 1.5 1 23 799 821 799 821 0.97
16 16 0.0014 0.088 12.5 0.1 2 23 827 848 826 848 0.93

Sequence Information

Coding Sequence
ATGAAGATAGTTTGTGctgcaaaaatatgtaaatactcTTTAGACAATGAAGACTCTAccaatatcaaatttattcatttcccAAACAATGATACATCAAAAATATGGGCACACCAGTGTGATAGAACAGACCTTTTAATGAAGTCTAATGAAGAATTgtatttaaactattatatatgttcTCATCATATAGAGGATCgctatttcataaataaaacaaatcctGTGATAATAGACCAACATGCTATTCCAACTTTATTTGAATCTCATactaatattgaaaaagattCGAGGAATGTCTTTGATAGAAATGAACAAACACAAATAGCTGATAATGTGTTATCATATTGTGATATGGATGTCGAAATAGATCAGTATCatgatatgaatattaaattttcaaatatatgtagaatatgCCAGGAATCATGTTTGGATggtatagaaatattttcattgaaaggGATAGACTTAAGGctgagagaaaaaataaatttacatctaCCAATTACAGTTAATATGGAAGATATAATGCCACAAAAATTGTGTATGAgctgttataataaattagaaattgcaCATTCATTAGCTGTAACATCGTTAAAAACAGAcatgaagttaaaaaaatttttgaacattaaTGTAGAACTAAATTATGATCATAGGTACAATGCAATAGTAAAGAAGTGTTCCGTAGAAATAACTGAAGAAATGTATATGAATGAAACAACTGAAGTTACATCTGTAAAGTTATCttctaacaaaattaatgaaatttctatgaatCACGAAgtcactgaaaaatttaatgactTGCAAAATACTAATATgcaaaaagataattttaaaaatataacaaaagaaGTGCAATCtgatttaaattgttttattgaatcacacaataaagaaattaaagaaaatgaatgtaCAACTAGAGTAACAAAAGATTATtcagaaaatgaaacattaaataatgCAATTCAATGCATTTATTGCAAGAATGTATTTAAAAcgcaagaaatatttgaaaatcacaAAATATTGTGTGTTGAAGAAGAAATAGTgatacagaaagaaaaaggaaccaataataatatgaataataaagaatccgataacataaaaataatgaacttcCAATTTGTAACGAaaacttgtaatatttgtcataaatattttgaaactgaaaaacaTTTCATTGAACATATCTCACACTGCAAATTTCTTCAAGAAGATTATCAAATTACTGAGCATAAAGCAATCGCAAAGACGGAACAGTGCAACAACTATAGAAATtcctataatattaataatctattGATAGAAACTAGTAGAAAATGTGGCCACTGTAATTTGatttctaatactaaaaaggaattattaaatcatattaTGGAATGTCATGAGGgccaacttttatttaaatgtattatgtGTGACAAAAGCTATGAAAAATGGGTTAGTTTAGACATACATGAAGCCACTCACAGACTAGATAAACCTTATCTATGCGATTTATGTGGAAAAAGCTTTAAACATTCCAATAATTTAAGAGGTCACAAAAGAACTCATTTAGATgattcaaaaaagaaacgacacaTTTGTGATATTTGTGGAAATGCATTTAGATCTAGATTTCATTTGGGAGAACATATGAACCAGCATAATGGAAATAAACCTTACTCTTGTGAAAAATGCGGCAAAGCTTTTTACAAAAGGATACAATTAAGACAGCATAAACTTTCCCATggtttaaataaacatatttgtcCAATTTGTGGGTCAGCTTTCAATCGTAAGGGAAATATGAATACACATCTTAAACGTCATAATAACAGAAAcgatatgtatacatgtagtATATGTAAACATAAATGTAAATCAATGAGTGAGTTGAAATCACATAGAAAAACTCATACAGAACAAGACATAGAAAATATAAGCAAACGGTGCATCGATAAAACTATATGGAAATGTAAGAGTTGTagtcgaatattttcaactcGAGCGGTATTATTGAATCATGAACGTATACATAAAAAAGACAGAATAAGTATCGACTGCAATATTTGTGGGAAGAAATTAGCgagtaaaaattctttaatatatcataaaaagtCTATTCATTCTTCGGAGAGACCGTACATATGTCAGTATTGCAAAGAATCGTTTGTTTCCAAAGAGTCGCGTCTTATACACGAAAGAATACATACCGGAGAACGTCCTTACGTctgcaaaatatgtaaaatggaATACAGACGTTCAAGCAATCTTAATCAACacatgaaaattcattctgaTATTAAGccttataaatgtatatactgtaataaaagtttcacaCGAAAAGGAGCGTTAAATGTACATGAGAGAGTTCACACTGGAGAGAAACCATTTGCCTGCCAAATATGCGATagaacattttctcaaaaaaatgaCATGATCAAGCACACTAAAACGCACGATGCCAAATCGTTGTCTTGCGAACAATGCGGTGAAGTGTtcataaagaagaaagatatcCTGAAACATATTGGTTTACATGAAGAAAATCCAATAATTCAGGAATATGTAGAGGTACAACAAGAAATGGAATCTTATAATGTAGATATAGTATGCTCTGAATTTGAGtga
Protein Sequence
MKIVCAAKICKYSLDNEDSTNIKFIHFPNNDTSKIWAHQCDRTDLLMKSNEELYLNYYICSHHIEDRYFINKTNPVIIDQHAIPTLFESHTNIEKDSRNVFDRNEQTQIADNVLSYCDMDVEIDQYHDMNIKFSNICRICQESCLDGIEIFSLKGIDLRLREKINLHLPITVNMEDIMPQKLCMSCYNKLEIAHSLAVTSLKTDMKLKKFLNINVELNYDHRYNAIVKKCSVEITEEMYMNETTEVTSVKLSSNKINEISMNHEVTEKFNDLQNTNMQKDNFKNITKEVQSDLNCFIESHNKEIKENECTTRVTKDYSENETLNNAIQCIYCKNVFKTQEIFENHKILCVEEEIVIQKEKGTNNNMNNKESDNIKIMNFQFVTKTCNICHKYFETEKHFIEHISHCKFLQEDYQITEHKAIAKTEQCNNYRNSYNINNLLIETSRKCGHCNLISNTKKELLNHIMECHEGQLLFKCIMCDKSYEKWVSLDIHEATHRLDKPYLCDLCGKSFKHSNNLRGHKRTHLDDSKKKRHICDICGNAFRSRFHLGEHMNQHNGNKPYSCEKCGKAFYKRIQLRQHKLSHGLNKHICPICGSAFNRKGNMNTHLKRHNNRNDMYTCSICKHKCKSMSELKSHRKTHTEQDIENISKRCIDKTIWKCKSCSRIFSTRAVLLNHERIHKKDRISIDCNICGKKLASKNSLIYHKKSIHSSERPYICQYCKESFVSKESRLIHERIHTGERPYVCKICKMEYRRSSNLNQHMKIHSDIKPYKCIYCNKSFTRKGALNVHERVHTGEKPFACQICDRTFSQKNDMIKHTKTHDAKSLSCEQCGEVFIKKKDILKHIGLHEENPIIQEYVEVQQEMESYNVDIVCSEFE