Basic Information

Gene Symbol
-
Assembly
GCA_014737525.1
Location
JACXIT010000131.1:1623467-1626568[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.012 1.1 10.0 0.5 2 21 330 349 329 350 0.93
2 16 0.16 15 6.4 1.6 2 20 387 405 386 407 0.92
3 16 0.0018 0.17 12.5 2.3 2 23 449 471 448 471 0.94
4 16 0.0049 0.46 11.2 0.2 1 23 477 499 477 499 0.96
5 16 3.2e-06 0.0003 21.2 3.4 1 23 505 527 505 527 0.96
6 16 0.00026 0.025 15.2 2.0 1 23 536 558 536 558 0.96
7 16 1.2e-05 0.0011 19.4 1.1 1 23 564 586 564 586 0.98
8 16 7.9e-07 7.4e-05 23.1 1.0 1 23 591 613 591 613 0.97
9 16 0.0047 0.44 11.3 7.1 1 23 620 642 620 642 0.99
10 16 0.0032 0.3 11.8 0.4 2 23 662 683 661 683 0.97
11 16 0.0011 0.1 13.2 0.3 3 23 692 713 690 713 0.95
12 16 0.00075 0.07 13.8 0.4 1 23 719 741 719 741 0.98
13 16 0.00051 0.048 14.3 2.7 1 23 747 769 747 769 0.98
14 16 2.4e-05 0.0023 18.5 0.7 1 23 775 797 775 797 0.95
15 16 2.5e-06 0.00024 21.6 1.4 1 23 803 825 803 825 0.97
16 16 0.00056 0.053 14.2 0.1 2 23 831 852 830 852 0.95

Sequence Information

Coding Sequence
ATGAAGATAGTTTGCGCTGCCAAAACTTGTAAATACTCTTTGGATAATGAAGACTCGACAAATGTCAAATTCATTCACTTTCCGAACAGTGATACTTCAAAAATATGGGCGCATCAGTGTGATAGAACGGATCTTTTAATGAAATCTAATGAAGAATTGTATTCAAATTATTATATATGTTCTCATCATATAGAAGATCGTTATTTCATAAATAAGACAGATCCTGTGATAATAGATCAACATGCTATTCCAACATTATTTGAATCTGATATTATTGCTGGAAAGGATTCAAAAAATGTCTTTGATAAAAATGAACAAACAGAAATAACTGATAATGTTATGTTATCATATTGTGATATGGATGTTGAAATGGATCAGTATCATGAAATCAGTATTAAATTTTCAAATTTATGTAGAATATGTGAAGAACCATGTTTCGATGGTATAGAAATATTTTCACTGAAAGGAATAGATCTAAGGCTAAGAGAAAAAATAAGTTTACATTTACCAATTATGGTTGATATGGAAGATATAATGCCACAGAAATTGTGCATGAATTGCTATAATAAATTAGAAGTTGCACATTCGTTAGTTATAACATCTTTAAGAACAGACATGAGGTTGAAAAAATTTTTGAATATTAATGCAGAACTAAATTATGATCATAAGTATAGTGCCATAGCAAAAAAGTGTTCCTTAGAAATAGATGAAGAAATGTCTATGAATGAAACAACTGATGTTACACCTGTAGAATTATCTTCTAACAAAATGAATGAAATTTCTATGAATCAGGAAGTCCCTAAAGAATTTAGTGACTTGGAAAATACCAATGTGCAAAAAGATAGTTTTCAAAATAGTATAAGAAAGGAAGTGCAATCTGAATTAAATAGCTTTATTGCATCACATAATGAGGAAATTAAAGAAGATGAATGTACAGATAGACTAACAAAAGATTATTCAGATAATGAAATATTAAATAATGAAATTCAATGCTTGTATTGTAAAAATATGTTTAAAACACAAGAGATGTTTGAAAATCACAAAATGTTGTGTGATGGAGGAGAAATAGTTGTACAGAAGGAAAAAGAAGCTAATAATAATATGAATGATAAAGAATCCAATAATGTAAAGATAATGAATTTTCAATTTATAACAAAAACTTGTAATGTTTGTCATGCAAATTTTGAAACTGAGAAACACTTTGTTGAACATAAACTTTCGTATTGTAAATTTCTTCAAGTAAAAGATTATCAAATTACTGATAAAATAATTATGAACAAAGAACAGTGCAATAATCATAAAGATTCCTACAATACCAATAATCTATCAATGGAAACCAATAAAAAATGTGGCCATTGTGGTTTGATTTATATTACTAAAAAGGAATTATTAAATCATATTATGGACTGTCATGAAGGTCAACTTCTATTTAAATGTATCATGTGTGATAGAAGCTATGAAAAGTGGTCTAGTTTAGATGTGCATGAAGCCACTCACAGGATAGATAAACCTTATTTATGTGATTTATGTGGAAAGAGTTTTAAACATTCCAATAATTTAAGAGGTCATAAGAGAACTCATTTGGATGATTCAAAAAAGAAACGACACATTTGTGACATTTGTGGAAATGCATTTAGATCTAGGTTTCATTTGGGAGAACATATGAATCAACATAATGGAAATAAACCTTACTCCTGTGAAGAGTGTGGCAAAGCTTTTTACAAAAGAATACAACTAAGACAGCATAAACTTTCTCATGGTTTGAATAAACATGTCTGTCCAATTTGTGGCACAGCTTTCAATCGTAAAGGAAACATGAATACACATCTTAAACGTCATAACAGTGGAGATGGTATATATACATGTAGCATATGTACACACACATGTAAATCAATGAGTGAACTAAAGTTACATAGAAAAAAACATACAGAACAAGACACTACAGAAAACATAGAAAAAAAACATATCGATAAACCTACATGGAAATGTAAGAGTTGTGACCGAATATTTTCAACTCGAGCGATATTATTAAATCATGAACGTATACATAAAGAAGATAAAATAAGTATCGATTGTAATATTTGTGGAAAAAAATTAGCAAGCAAAAATTCTCTGGTGTATCATAAAAAATCCATTCATTCTTCGGAGAGACCGTATATGTGTCAATATTGTGAAGAATCGTTTGTTTCCAAAGAATCACGTCTTATACACGAAAGAATACATACCGGAGAACGTCCTTACGTTTGCAAAATATGTAAAATGGAATACAAATGTTCAAGCAATCTTAATCAACACATAAAAATTCATTCTGGGATTAAGCCTTATATATGTATATATTGTAATAAAAGTTTCACGCGTAGAGGAACGTTAAATGTGCATGAGAGAATACATACTGGAGAGAAACCATTTGCTTGCGAAACGTGTGGTAGAACATTTTCTCAGAAAAATGACATGATCAAGCACACTAAAACACATAATGCCAAATCGTTGTCTTGTGAACAATGCAATGAAGTTTTCGCAAGGAAGAAAGATATCCTAAAGCATATTGCTTTGCACGAACAAAATAGTCCTATAATTCAGGAGTATGTAGAGATACAACAAGAAATAGAACCTTACAGTGTGGATATAGCATGCTCTGAATTTGAATAA
Protein Sequence
MKIVCAAKTCKYSLDNEDSTNVKFIHFPNSDTSKIWAHQCDRTDLLMKSNEELYSNYYICSHHIEDRYFINKTDPVIIDQHAIPTLFESDIIAGKDSKNVFDKNEQTEITDNVMLSYCDMDVEMDQYHEISIKFSNLCRICEEPCFDGIEIFSLKGIDLRLREKISLHLPIMVDMEDIMPQKLCMNCYNKLEVAHSLVITSLRTDMRLKKFLNINAELNYDHKYSAIAKKCSLEIDEEMSMNETTDVTPVELSSNKMNEISMNQEVPKEFSDLENTNVQKDSFQNSIRKEVQSELNSFIASHNEEIKEDECTDRLTKDYSDNEILNNEIQCLYCKNMFKTQEMFENHKMLCDGGEIVVQKEKEANNNMNDKESNNVKIMNFQFITKTCNVCHANFETEKHFVEHKLSYCKFLQVKDYQITDKIIMNKEQCNNHKDSYNTNNLSMETNKKCGHCGLIYITKKELLNHIMDCHEGQLLFKCIMCDRSYEKWSSLDVHEATHRIDKPYLCDLCGKSFKHSNNLRGHKRTHLDDSKKKRHICDICGNAFRSRFHLGEHMNQHNGNKPYSCEECGKAFYKRIQLRQHKLSHGLNKHVCPICGTAFNRKGNMNTHLKRHNSGDGIYTCSICTHTCKSMSELKLHRKKHTEQDTTENIEKKHIDKPTWKCKSCDRIFSTRAILLNHERIHKEDKISIDCNICGKKLASKNSLVYHKKSIHSSERPYMCQYCEESFVSKESRLIHERIHTGERPYVCKICKMEYKCSSNLNQHIKIHSGIKPYICIYCNKSFTRRGTLNVHERIHTGEKPFACETCGRTFSQKNDMIKHTKTHNAKSLSCEQCNEVFARKKDILKHIALHEQNSPIIQEYVEIQQEIEPYSVDIACSEFE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00734082;
90% Identity
iTF_00215855;
80% Identity
-