Dtru011505.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila truncata
Gene Symbol
su(Hw)
Assembly
GCA_008042515.1
Location
VNJQ01001065.1:47368-50533[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00056 0.049 14.2 1.9 1 20 226 245 226 247 0.94
2 11 2.2e-06 0.00019 21.8 0.4 3 23 298 319 296 319 0.93
3 11 0.06 5.2 7.8 0.1 1 23 325 347 325 347 0.94
4 11 4.3e-07 3.7e-05 24.0 2.4 1 21 354 374 354 375 0.95
5 11 4.9e-06 0.00042 20.7 1.0 2 23 387 408 386 408 0.96
6 11 0.4 35 5.2 2.5 1 17 419 435 419 435 0.92
7 11 7.9e-05 0.0069 16.9 0.1 2 23 435 456 434 456 0.96
8 11 1.2e-06 0.0001 22.6 2.5 1 23 462 484 462 484 0.98
9 11 2e-05 0.0017 18.7 1.4 1 23 488 510 488 510 0.97
10 11 5.1e-05 0.0044 17.5 0.4 1 22 518 539 518 542 0.91
11 11 4.1e-05 0.0036 17.7 0.9 3 23 563 584 561 584 0.95

Sequence Information

Coding Sequence
ATGAGCGCGTCCAAGGAGGCCAAGGACAAGAAGGGCGGCATCAAGATTCTGGGAGTGGAGAACATTTCGCCACCGAAGGAATCATCACGCCCCGCCACACGCATGAAGCTGCTAAACGAGGCCgcaggagctgctgctcctccgtcTGTTTCCTCGACCAAGACGGAAAAGCGcaacagcggcggcggcgggggaTCCCGCATTAAAATTCTCAATGACGACGCACTGGGCCTGCCAAAGAGCGAGAAACGAGGCTCCCTGTCGAAGACCAGTCCTCGGAACACTAGCACCTCCACTTCCACCTCTGTAAAGATCTTAAATGTAAAGCGATCTGCCCCCGCCACCGCCATTACAGCCCTGGAAACCAAGATCCGTCCCTCGGCCAGCAGGAAGCAGAATATGGATCACTACGTGCTCCAAGCAGTGAAGACGGAGAATAGCAAGCAGCAGGCAGTCACAACGGCGCGACGTTCGACGGTGTCGGATAACGCGGAGACCGAAACCATGGCTTTCATACTGGCGGACGACGACGAGGTGGTGCCCGGTACTTTGGAACGGACGAATGGGCAGGAGGAGATCGTTGTCACCGAaaacgacgaggaggaggaggaagaggaagacgGCGAGGCAAACAAGGACGAGGCTGGCAAGAGCGGAATGAAGGAGATTGTGGAACATGTGTGCGGCAAGTGCTACAAGACCTTCCGGCGCATCAAGAGCTTGACAAAGCACTTGGAGTTCTGTCGCTACGACAGCGGCTACCATCTGCGTAAGGCGGACATGCTCAAGAACCTAGAAAAGATCGAGAAAGATGCCGTGGTGATGGAAAAGAAGGAtatctgcttctgctgcagcGAAAGCTACGACACCTTCCATTTGGGCCACATCAACTGTCCGGACTGCCCGAAGTCGTTCAAGACGCAGACCAGCTACGAGCGACACATCTTCATCACGCACTCGGAGTTCTGTGACTTTCCCTGCTCCATCTGCAATGCCAATCTGCGTAGCGAGGCGTTGCTTAAGCTGCACGAGGAACAGCACAAGTCGCGGGGAAAGCCGTACGCCTGCAAGATCTGTGGTAAGGATTTTACGCGCTCCTATCATTTGAAGCGCCATCAGAAGTACTCTGCTTGCTCGGCCAACGAGACCGATACCATGAGCTGCAAGGTGTGCGATCGTGTCTTTTATCGTTTGGACAACCTGCGATCGCACTTAAAGCAGCATTTGGGCACGCAGGTGATGAAGAAGCCGGAGTACATGTGTCACGTTTGCAAGAATTGCTTTTACAGCTTGTCCACACTTAACTGCACTGTGTGCAATCAAGCCTTTGCTGTGAAGGAGGTGCTCAATCGACACATGAAACGGCACACGGGCGAGCGTCCGCACAAGTGTGAGGAGTGTGGCAAGAGCTTCATCCAGGCCACACAGCTGCGCACGCATTCCAAGACCCACGTCCGGCCCTTTAGCTGTGATCAGTGCGAGGAGAAGTTCAAGACCCAGAAGCAACTCGAGCGTCATGCGAAGGAGCACTCCTCCCAGAAGCGCCCCGTCTTCTCTTGCACCGAATGCAAGCGTAATTTCCgcagcacagcacagctcAAGGAGCACATGGATGTGGGCGTTCACACACCCAAGCCCACGCGTGCCACCAAGCGCTCACCCGCAAAGGTTTTGGAGCGCACGGATTGCGCCATTTGTGACAAGAACTTCGACAGCTGCGAAACTCTTCGCCGGCACATTCGCGCCGTTCACGAATGTGATCCGGATGACATCTTTGGCGTCGATCCGCTAGCATCAAAGCGTAGCAAGAGAACTAAATTGGTAACGGTGAAGGAGcaggatcaggatcaggatcaggaGCATGAGGAGATTGTACCAGTGGCGCTGAACACTTCAGCGGGTTCGTTGATTTCCAGCCAAACGGATGGCAATGGCGTTGTGGTGCGTGAGTATCTGGTGGACGAGACCGATGAGACGGCGGCTCAGACCATTACGCTGGAGAACGAGACATATACGATTCTCCCGCTGGACATTGAGGCCGAGCAGCTGACAGATGAGGTTTCGGTGGAAGTGAAGCCCGAAGGCAAAAAGGAAGAAGTCTCGCCGGTGGTCAAGAAAGAGAAGCGAAAGTCGTTGGCTGCCAGCTTGGCGGCTGCCATCGCTGATAATCTGGAGGAGGAGCCATCCAGCGAGGACGATCCAGGCGGCGAAGTCCTAACCGAAGAGGACCTCAAGCTTAAGGAAAACATTGGTAAACTCATCGACATGCTGGTGGATCCGCCCATCTTGAAGAAGTATGGCTGGCCCAATGCCCCCGAGGAGACGGTGCTATGCAAGGTAATCGAGAACTGCGGCCACGATCTGACCAAAGGTAGTGAGAACTACGCGGAGTTGGATTACGGCAGCCGAATGCGCGAATACTGCAAGCTGCTCTTTACCGTGGTCATACACAACGACTCCATCAAGTCGCTGCTCAATAATTTTCCCATTGACGATGTCATCGAGTATGTTTTGGGCGATGAGGATCAGGAGGAAGGCGGTGGCTTGGGAGGTATAGGTGAGGACGACGAAGAAGGGGAGTCGGGGGAGAAGGAAGATAAAAGGACAgcaaagaaacagaaaaagtcCGAAACCGAAATAGAAGAGATAATCACAGGTGATCTGGATtctgaggaggaggaggagaaggaggaggaaactGTCGAAAAAGTAAAACGAGGAAAAAAGGCTTGA
Protein Sequence
MSASKEAKDKKGGIKILGVENISPPKESSRPATRMKLLNEAAGAAAPPSVSSTKTEKRNSGGGGGSRIKILNDDALGLPKSEKRGSLSKTSPRNTSTSTSTSVKILNVKRSAPATAITALETKIRPSASRKQNMDHYVLQAVKTENSKQQAVTTARRSTVSDNAETETMAFILADDDEVVPGTLERTNGQEEIVVTENDEEEEEEEDGEANKDEAGKSGMKEIVEHVCGKCYKTFRRIKSLTKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFCDFPCSICNANLRSEALLKLHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSACSANETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVMKKPEYMCHVCKNCFYSLSTLNCTVCNQAFAVKEVLNRHMKRHTGERPHKCEECGKSFIQATQLRTHSKTHVRPFSCDQCEEKFKTQKQLERHAKEHSSQKRPVFSCTECKRNFRSTAQLKEHMDVGVHTPKPTRATKRSPAKVLERTDCAICDKNFDSCETLRRHIRAVHECDPDDIFGVDPLASKRSKRTKLVTVKEQDQDQDQEHEEIVPVALNTSAGSLISSQTDGNGVVVREYLVDETDETAAQTITLENETYTILPLDIEAEQLTDEVSVEVKPEGKKEEVSPVVKKEKRKSLAASLAAAIADNLEEEPSSEDDPGGEVLTEEDLKLKENIGKLIDMLVDPPILKKYGWPNAPEETVLCKVIENCGHDLTKGSENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEEGGGLGGIGEDDEEGESGEKEDKRTAKKQKKSETEIEEIITGDLDSEEEEEKEEETVEKVKRGKKA