Djam007678.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila jambulina
Gene Symbol
su(Hw)
Assembly
GCA_018152175.1
Location
JAECXH010000012.1:31260363-31263548[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00063 0.045 14.1 1.9 1 20 227 246 227 248 0.94
2 12 2.5e-06 0.00018 21.7 0.4 3 23 299 320 297 320 0.93
3 12 0.067 4.9 7.7 0.1 1 23 326 348 326 348 0.94
4 12 4.8e-07 3.5e-05 23.9 2.4 1 21 355 375 355 376 0.95
5 12 5.5e-06 0.0004 20.6 1.0 2 23 388 409 387 409 0.96
6 12 9.2e-05 0.0067 16.7 5.3 1 23 420 442 420 442 0.99
7 12 0.00025 0.018 15.4 0.8 1 23 448 470 448 470 0.97
8 12 1.7e-05 0.0012 19.1 0.4 1 23 476 498 476 498 0.98
9 12 1.3e-06 9.8e-05 22.5 2.5 1 23 504 526 504 526 0.98
10 12 1.3e-05 0.00093 19.4 1.6 1 23 530 552 530 552 0.97
11 12 5.7e-05 0.0042 17.4 0.4 1 22 560 581 560 584 0.91
12 12 1e-05 0.00076 19.7 1.4 3 23 605 626 603 626 0.97

Sequence Information

Coding Sequence
ATGAGCGCGTCCAAAGAGGGCAAGGACAAGAAGGGCGGAATCAAGATACTGGGAGTGGAGAACATCTCGCCGCCGAAGGAAACGTCGCGCCCCGCCACACGCATGAAGCTGCTGAACGAAGCCGCAGCAGCAGGAGCCTCTGCTCCGTCTCCGTCTGTTTCCCCAACCAAGTCGGAAAAGCGCAACAGCGGCGGCGGTGGGGGATCCCGCATCAAAATACTCAATGACGAGGCACTGGGGCTGCCAAAGGCCGAGAAACGTGGCTCAACATCTAAGACCAGTCCGCGCAACGCCAGCGCCACCTCCACCTCTGTGAAGATCTTAAACGTGAAGCGCCCTGCCTCCACTTCCGTTACAGCCGTGGAAACCAAGAACCGTGCCTCTCCCAGCAAGAAGCAGAAGATGGATCACTACGTGCTCCAAGCGGTCAAATTGGAAAACACCAAGCAGCAAGCAGTCACCACGGCGCACCGTGCGGCGACGTCGGAAAACGAGGAGACCGAGACCATTGCCTTCATACTGGCGGACGACGACGAGGTGGTGCCAGGAACGTTGGAACGGACGAACGGCCAGGAGGAGATCGTCGTGACTGAAAACGATGATGAGGAGGAGGAGGAGGAAGGCGGCGAGGCGGATAAGGACGAGGCTGGCAAGGGCGGGATGAAGGAGATTGTGGAACATGTGTGCGGCAAGTGTTACAAGACCTTCCGGCGCATCAAGAGCCTGACAAAGCACTTGGAGTTCTGCCGTTACGACAGCGGCTACCACCTGCGCAAGGCGGATATGCTCAAGAACCTGGAGAAGATCGAAAAGGATGCGGTGGTGATGGAAAAGAAGGATATCTGTTTCTGCTGCAGCGAAAGCTACGACACCTTCCATTTGGGCCACATCAACTGTCCGGACTGCCCAAAGTCGTTTAAGACCCAAACCAGCTACGAGCGCCACATCTTCATCACGCACTCGGAATTTTGTGACTTTCCCTGCTCCATTTGCAATGCCAATCTGCGCAGCGAGGCGTTGCTGAAGCTTCACGAGGAACAGCACAAGTCAAGGGGCAAGCCGTACGCCTGCAAGATATGCGGCAAGGATTTCACGCGCTCCTATCACCTGAAGCGCCATCAGAAATACTCGGCCTGCTCGGCCAATGAGACCGATACCATGAGCTGCAAGGTTTGCGATCGCGTCTTTTATCGTTTGGACAACCTGCGATCGCACTTGAAGCAGCATTTGGGCACGCAGGTGATGAAGAAGCCGGAGTACATGTGTCACGTTTGCAAGAATTGCTTTTACAGCTTGTCCACGCTCAACATTCACATACGCACGCATACGGGTGAGAAGCCTTTTGATTGCGATCTATGTGAGAAGAAGTTCTCAGCTTTGGTGGCCCTTAAGAAGCATCGTCGCTATCACACGGGCGAGAAACCCTACAGCTGCACTGTGTGTAATCAAGCCTTTGCTGTGAAGGAGGTCCTAAATCGCCACATGAAACGGCACACGGGCGAGCGTCCGCACAAGTGTGAGGAGTGTGGCAAGAGCTTTATCCAGGCTACACAGCTCCGCACGCATTCCAAAACACACATTCGGCCCTTTAGTTGTGATCAGTGCGAAGAGAAGTTCAAGACGCAAAAGCAACTTGAGCGACATGTGAAGGAGCACAATACCCAGAAGCGCCCCGTCTTCTCCTGCACCGAATGCAAGCGCAACTTCCGCAGCACAGCTCAGCTTAAGGAGCACATGGATGTGGGCGTTCACACACCCAAGCCCACGCGTGCCACCAAGCGCTCGCCCGCCAAGGTTATGGAGCGCACGGACTGCGCCATTTGTGACAAGAACTTCGACAGTTGCGAAACTCTGCGCCGGCACATTCGCACTGTCCACGAATGTGATCCGGATGACATCTTTGGCGTGGATCCGCTAATAGCGAAACGGGGCAAGAGAGCCAAATTGGCGACGGTGGAGGAGCAGGAACAGGATCATGAGGAGATTGTACCAGTGGCGCTGAACACATCAGCGGGTTCGTTGATTTCCAGCCAAACGGATGGAAATGGCGTTGTGGTGCGTGAGTATCTGGTGGACGAGACCGATGAGACGGCGGCCCAGACCATTACGCTTGAGAACGAGACATATACGATTCTCCCGCTGGACATGGAGGGCGAGCAGCTGACGGATGAGACGTCTGTCGCAGTCAAGCCCGAGAGCAAAAAGGAAGAAGGAGGACCGAAGGTCTCGCCGGTGGTCAAGAAGGAGAAGCGCAAGTCCTTGGCTGCCAGCTTGGCGGCTGCTATCGCTGATAATTTGGAGGAGGAGCCATCTAGCGAGGACGATGGCAGCGGCGAAGTCCTAACCGAGGAGGACCTCAAGCTTAAGGAAAACATTGGCAAGTTGATCGACATGCTGGTGGATCCGCCTATCTTAAAGAAGTATGGCTGGCCCAATGCCCCCGAAGAGTCAGTGCTCTGCAAGGTGATCGAGAATTGCGGCCACGATCTGACCAAAGGTAGTGAGAACTACGCGGAGTTGGACTACGGTAGCCGGATGCGTGAGTACTGCAAGCTGCTCTTCACCGTGGTCATACACAACGACTCCATCAAATCGCTGCTCAACAACTTTCCTATTGACGATGTCATCGAGTATGTACTAGGCGATGAGGATCAGGAGGAAGGCGGTGGCTTGGGAGGCATAGGTAAGGACGACGAAGAAGGGGAGCCGGAAGAAGAAGAAATAAGTACAGCGAAGAAACAGAAAAAATCGGAAACGCAAATAGGAGAGACAATCACAGGTGATCTGGATTCCGAGGGGGAGAACGAGGAAGCGGTCGAAAAGGAAAAGGACACAGCTGAAAAAAAAGGGAAAAAGGCTTGA
Protein Sequence
MSASKEGKDKKGGIKILGVENISPPKETSRPATRMKLLNEAAAAGASAPSPSVSPTKSEKRNSGGGGGSRIKILNDEALGLPKAEKRGSTSKTSPRNASATSTSVKILNVKRPASTSVTAVETKNRASPSKKQKMDHYVLQAVKLENTKQQAVTTAHRAATSENEETETIAFILADDDEVVPGTLERTNGQEEIVVTENDDEEEEEEGGEADKDEAGKGGMKEIVEHVCGKCYKTFRRIKSLTKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFCDFPCSICNANLRSEALLKLHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSACSANETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVMKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCEKKFSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGERPHKCEECGKSFIQATQLRTHSKTHIRPFSCDQCEEKFKTQKQLERHVKEHNTQKRPVFSCTECKRNFRSTAQLKEHMDVGVHTPKPTRATKRSPAKVMERTDCAICDKNFDSCETLRRHIRTVHECDPDDIFGVDPLIAKRGKRAKLATVEEQEQDHEEIVPVALNTSAGSLISSQTDGNGVVVREYLVDETDETAAQTITLENETYTILPLDMEGEQLTDETSVAVKPESKKEEGGPKVSPVVKKEKRKSLAASLAAAIADNLEEEPSSEDDGSGEVLTEEDLKLKENIGKLIDMLVDPPILKKYGWPNAPEESVLCKVIENCGHDLTKGSENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEEGGGLGGIGKDDEEGEPEEEEISTAKKQKKSETQIGETITGDLDSEGENEEAVEKEKDTAEKKGKKA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00612944;
90% Identity
iTF_00492363;
80% Identity
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