Dtan012428.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila tani
Gene Symbol
su(Hw)
Assembly
GCA_008042535.1
Location
VNJO01003466.1:156047-159440[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00068 0.059 14.1 1.9 1 20 230 249 230 251 0.94
2 11 2.6e-06 0.00023 21.7 0.4 3 23 302 323 300 323 0.93
3 11 0.073 6.3 7.7 0.1 1 23 329 351 329 351 0.94
4 11 5.2e-07 4.5e-05 23.9 2.4 1 21 358 378 358 379 0.95
5 11 5.9e-06 0.00051 20.6 1.0 2 23 391 412 390 412 0.96
6 11 0.00027 0.023 15.4 0.8 1 23 434 456 434 456 0.97
7 11 1.8e-05 0.0016 19.1 0.4 1 23 462 484 462 484 0.98
8 11 1.5e-06 0.00013 22.5 2.5 1 23 490 512 490 512 0.98
9 11 7.8e-05 0.0068 17.1 0.9 3 23 518 538 516 538 0.97
10 11 6.2e-05 0.0054 17.4 0.4 1 22 546 567 546 570 0.91
11 11 7.4e-06 0.00064 20.3 1.5 3 23 591 612 589 612 0.97

Sequence Information

Coding Sequence
ATGAGCGCCGCCAAGGAGGGCAAGGACAAGAAGGGCGGCGTCAAGATACTGGGCGTGGAGAATGTCTCGCCGCCGAAGGACACGTCGCGCCCCGCCACGCGCATGAAGCTGCTGAACGAGGCCGCAGCAGCGGGAGCCGCTTCGTCGCCGTCTGTTTCCCCCACCAAGACGGAGAAGGgcaacagcggcggcggcggaggcgggggATCCCGCATCAAAATACTGAATGACGAGGCCCTGGGCCTGCCAAAGACGGAGAAGCGAGGCTCCACATCCAAGACCAGTCCGCGCaataccaccaccaccacgaccTCCACCTCCGTGAAGATCCTCAATGTAAAGCGccctgccaccgccaccgccgtgACGCCCCTGGAGACCAAGATCCGAGCCTCGCCCGGCAAGAAGCAGAAGATGGATCACTATGTGCTCCAGGCGGTCAAGTTGGAGAACAGCAAGCAGCAAGCGGTCACCACGGCGCACCGCGCGGCGGCGTCGGAGAACGATGAGACCGAGACCATTGCCTTTATACTGGCCGAAGACGATGAGGTGGTGCCGGGCACGTTGGAACGAACGAATGGCCAGGAAATCGTCGTCACCGAAGGCgacgaggaggaagaggacgacgacggcgTCGAGGCGGACAAGAGCGAGGGCGGCAAGGGCGGAATCAAGGAGATTGTGGAGCATGTGTGCGGCAAGTGCTACAAGACGTTCCGGCGCATCAAGAGCCTGACAAAGCACCTGGAGTTCTGTCGCTACGACAGCGGCTACCATCTGCGCAAGGCGGACATGCTCAAGAACCTGGAGAAGATCGAGAAGGATGCGGTGGTGATGGAGAAGAAGGATATCTGTTTCTGCTGCAGCGAAAGCTACGACACCTTCCATTTGGGCCACATCAACTGCCCCGACTGCCCCAAGTCGTTCAAGACGCAGACCAGCTACGAGCGCCACATCTTCATCACGCACTCGGAGTTCTGTGACTTTCCCTGCTCCATCTGCAATGCCAATCTGCGCAGCGAGGCGCTGCTGAAGCTGCACGAGGAGCAGCACAAGTCGCGGGGCAAGCCGTATGCCTGCAAGATCTGCGGCAAGGACTTTACGCGCTCGTACCACTTGAAGCGCCATCAGAAGTACTCGGCATGCTCGGCCAACGAGACCGATACCATGAGCTGCAAGGTCTGCGATCGCGTCTTTTATCGCCTGGACAACCTGCGCTCGCACCTGAAGCAGCATCTGGGCACGCAGGTGATGAAGAAGCCCGACATTCACATACGCACGCACACGGGCGAGAAACCCTTCGATTGCGATCTCTGCGAGAAGAAGTTCTCCGCCTTGGTGGCCCTCAAGAAGCATCGTCGCTATCACACGGGCGAGAAGCCCTACAGTTGCACTGTGTGCAACCAAGCCTTTGCCGTCAAGGAGGTGCTCAATCGCCACATGAAGCGGCACACGGGCGAGCGTCCGCACAAGTGCGAGGAGTGTGGCAAAAGCTTCATCCAGGCCACACAGCTGCGCACCCATTCCAAGACCCATGTGCGGCCCTTTGGCTGTGATCAGTGCGAGGAGAAGTTCAAAACGCAGAAGCAACTCGAGCGCCATGTCAAGGAGCACTCTTCCCAGAAGCGTCCCGTCTTCTCCTGCACCGAATGTAAGCGCAACTTCCGTAGCACAGCACAGCTCAAGGAGCACATGGATGTGGGCGTACACACACCCAAGCCCACGCGCGCCGTCAAGCGCTCGCCCACCAAGGTTATGGAGCGAACGGATTGCGCCATTTGTGACAAGAACTTCGACAGCTGCGACACTCTCCGCCGCCACATCCGCACCGTGCACGAATGCGATCCGGATGACATCTTTGGCGTGGATCCTCAAACTGCGAAGCGTGGCAAGAGGGCCAAGCTGGCGACAGcagaggagctgcaggagcaggagccggaggagaTTGTACCAGTGGCGCTGAACACTTCAGCGGGTTCGCTGATCTCCAGCCAAACGGATGGCAACGGCGTGGTGGTGCGTGAGTATCTGGTGGACGAAACCGATGACACGGCGGCCCAGACCATTACGCTGGAGAACGAGACGTACACGATTCTCCCACTGGACATTGAGGGCGAGCAGCTGGCCGATGAGACGGCGGCGGTGGGAGTCAAGCCCGAGGGCAAAAAGGAGGAAGGCGTGAAGGTCTCGCCGGTGGTCAAGAAGGAGAAGCGCAAATCGTTGGCCGCCAGCCTGGCGGCTGCCATTGCTGATAatctggaggaggagccgtCGAGCGAGGACGATGCCAGCGGCGGCGAAGTCCTTACCGAGGAGGACCTCAAGCTCAAGGAGAACATTGGCAAGTTGATCGACATGCTGGTGGATCCGCCCATCCTAAAGAAATATGGCTGGCCCAACGCCCCCGAGGAGACGGTGCTCTGCAAGGTGATCGAGAACTGCGGCTACGACCTGGTCAAGGGTGGCGAGAACTACGCTGAGCTGGACTATGGCAGCCGGATGCGCGAGTACTGCAAGCTGCTCTTCACCGTCGTCATACACAACGACTCCATCAAGTCGCTGCTCAACAACTTTCCCATCGACGATGTCATCGAGTATGTGCTGGGCGATGAGGATCAGGaggatggcggcggcgggctgGGATGCAAGGGCAAGGACGCTGACGAAGAGGAGCAGGAAGAAGGGGAAAGCAGTCCGAAGAAGTCGGGAGCCGGAGAAGGGGAGACCATCACAGGCGATCCGGAGTCCGAGGACGAGGAAACGGTCGGTAAGGAAAAGGACACAGCTGAAATCGATGGAAAAAAGGCTTAG
Protein Sequence
MSAAKEGKDKKGGVKILGVENVSPPKDTSRPATRMKLLNEAAAAGAASSPSVSPTKTEKGNSGGGGGGGSRIKILNDEALGLPKTEKRGSTSKTSPRNTTTTTTSTSVKILNVKRPATATAVTPLETKIRASPGKKQKMDHYVLQAVKLENSKQQAVTTAHRAAASENDETETIAFILAEDDEVVPGTLERTNGQEIVVTEGDEEEEDDDGVEADKSEGGKGGIKEIVEHVCGKCYKTFRRIKSLTKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFCDFPCSICNANLRSEALLKLHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSACSANETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVMKKPDIHIRTHTGEKPFDCDLCEKKFSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGERPHKCEECGKSFIQATQLRTHSKTHVRPFGCDQCEEKFKTQKQLERHVKEHSSQKRPVFSCTECKRNFRSTAQLKEHMDVGVHTPKPTRAVKRSPTKVMERTDCAICDKNFDSCDTLRRHIRTVHECDPDDIFGVDPQTAKRGKRAKLATAEELQEQEPEEIVPVALNTSAGSLISSQTDGNGVVVREYLVDETDDTAAQTITLENETYTILPLDIEGEQLADETAAVGVKPEGKKEEGVKVSPVVKKEKRKSLAASLAAAIADNLEEEPSSEDDASGGEVLTEEDLKLKENIGKLIDMLVDPPILKKYGWPNAPEETVLCKVIENCGYDLVKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEDGGGGLGCKGKDADEEEQEEGESSPKKSGAGEGETITGDPESEDEETVGKEKDTAEIDGKKA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00612944;
90% Identity
iTF_00483105;
80% Identity
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