Basic Information

Insect: Drosophila kanapiae
Gene Symbol: su(Hw)
Assembly: GCA_008042475.1
Location: VNJM01000637.1:216687-219824[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00063 0.05 14.1 1.9 1 20 222 241 222 243 0.94

2 12 2.5e-06 0.0002 21.7 0.4 3 23 294 315 292 315 0.93

3 12 0.068 5.4 7.7 0.1 1 23 321 343 321 343 0.94

4 12 4.8e-07 3.9e-05 23.9 2.4 1 21 350 370 350 371 0.95

5 12 5.5e-06 0.00044 20.6 1.0 2 23 383 404 382 404 0.96

6 12 9.3e-05 0.0074 16.7 5.3 1 23 415 437 415 437 0.99

7 12 0.00025 0.02 15.4 0.8 1 23 443 465 443 465 0.97

8 12 1.7e-05 0.0013 19.1 0.4 1 23 471 493 471 493 0.98

9 12 1.4e-06 0.00011 22.5 2.5 1 23 499 521 499 521 0.98

10 12 0.0002 0.016 15.7 1.2 1 23 525 547 525 547 0.97

11 12 4.3e-05 0.0034 17.8 0.4 1 22 555 576 555 579 0.91

12 12 6.9e-06 0.00055 20.3 1.5 3 23 600 621 598 621 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00063	0.05	14.1	1.9	1	20	222	241	222	243	0.94
2	12	2.5e-06	0.0002	21.7	0.4	3	23	294	315	292	315	0.93
3	12	0.068	5.4	7.7	0.1	1	23	321	343	321	343	0.94
4	12	4.8e-07	3.9e-05	23.9	2.4	1	21	350	370	350	371	0.95
5	12	5.5e-06	0.00044	20.6	1.0	2	23	383	404	382	404	0.96
6	12	9.3e-05	0.0074	16.7	5.3	1	23	415	437	415	437	0.99
7	12	0.00025	0.02	15.4	0.8	1	23	443	465	443	465	0.97
8	12	1.7e-05	0.0013	19.1	0.4	1	23	471	493	471	493	0.98
9	12	1.4e-06	0.00011	22.5	2.5	1	23	499	521	499	521	0.98
10	12	0.0002	0.016	15.7	1.2	1	23	525	547	525	547	0.97
11	12	4.3e-05	0.0034	17.8	0.4	1	22	555	576	555	579	0.91
12	12	6.9e-06	0.00055	20.3	1.5	3	23	600	621	598	621	0.97

Sequence Information

Coding Sequence: ATGAGCGCCTCCAAGGAGGGCAAGGACAAGAAGGGCGGCATCAAGATTTTGGGCGTGGAAAACATCTCGCCGCCGAAGGACACGTCGCGCCCCGCCACGCGCATGAAGCTGCTGAACGAGGCCGCAGCCGCAGGAGCCGCTGCGTCGCCGTCTGTTTCCCCGACTAAGACGGAAAAGCgcaacagcggcggcggggGATCCCGCATCAAAATACTCAATGACGAGGCACTGGGCCTGCCAAAGACCGAGAAACGTGGCGCCACATCCAAGACCAATCCGCGCACCTCCACATCCGTGAAGATCCTGAATGTAAAGCGCCCTGCCTCCGCCACCGCTATTACCGCCATGCAAACCAAGATCCGGGCCATGCCCAGCAAGAAGCAGAAGATGGATCACTATGTGCTCCAAGCGGTCAAGACGGAgaacagcaagcagcaagcGGTCACCACAGCACACCGTGCGGCGACGACGGAGAACGAGGAGACCGAGACCATTGCCTTCATACTGGCCGACGATGACGAGGTGGTGCCGGGAACTTTGGAACGGACGAATGGCCAGGAGGAGATCGTGGTCACCGAAaacgatgatgaggaggaggaggaagagggcGGCGAGGCGGATAAGGACGAGGCCGGCAAGGGCGGAATCAAGGAGATTGTGGAGCATGTGTGCGGCAAGTGCTACAAGACGTTCCGGCGCATCAAAAGCCTGACAAAGCATTTGGAGTTCTGTCGCTACGACAGCGGCTACCATCTGCGCAAGGCGGACATGCTGAAGAACCTGGAGAAGATCGAAAAGGATGCGGTGGTGATGGAGAAGAAGGACATCTGTTTCTGCTGCAGCGAAAGCTACGACACCTTTCATTTGGGCCACATCAACTGTCCCGACTGCCCCAAGTCGTTCAAGACGCAGACCAGCTACGAGCGCCACATCTTTATCACGCACTCGGAGTTCTGTGACTTTCCCTGCTCCATCTGCAATGCCAATCTGCGCAGCGAGGCGTTGCTGAAGCTGCACGAGGAGCAGCACAAGTCGCGTGGCAAGCCGTACGCCTGCAAGATCTGCGGCAAGGATTTCACGCGCTCCTACCACCTGAAGCGGCATCAGAAGTATTCGGCCTGCTCGGCCAACGAGACCGATACCATGAGCTGCAAGGTGTGCGATCGCGTCTTCTATCGTCTGGACAACCTGCGGTCCCACTTGAAGCAGCATTTGGGCACTCAGGTGATGAAGAAACCGGAGTACATGTGTCACGTTTGCAAGAACTGCTTCTACAGCTTGTCCACGCTCAACATTCATATACGCACGCATACGGGCGAGAAACCCTTTGATTGCGATCTTTGTGAGAAGAAGTTTTCCGCTTTGGTGGCCCTCAAGAAGCACCGTCGGTATCACACGGGCGAGAAGCCCTACAGCTGCACTGTTTGCAATCAAGCCTTTGCCGTCAAGGAGGTGCTCAATCGCCACATGAAGCGGCACACGGGCGAGCGACCGCACAAGTGCGAGGAGTGTGGCAAGAGCTTCATCCAGGCCACTCAGCTGCGGACCCATTCCAAGACCCACGTTCGCCCCTTTCCATGTGATCAGTGCGAGGATAAGTTCAAGACGCAGAAGCAaCTCGAGCGCCATCTGAAGGAGCACTCTTCCCAGAAACGTGCCGTCTTCTCTTGCACCGAATGCAAGCGCAACTTCCGCAGCACAGCTCAGCTCAAGGAACACATGGAGGTCGGCGTTCACACACCCAAGCCCCAACGGGTCTCCAAGCGCACACCCGCCAAGGTAATGGAGCGCACGGATTGCGCAATTTGCGATAAGAACTTCGACAGCTGCGACACTCTGCGTCGACACATTCGCACCGTCCACGAATGCGATCCTGATGACATCTTCGGTGTGGATCCTCAAACCGCGAAGCGTGGAAAGCGAGCCAAATTGGCCACGGTGGCCGAGCAGGATCAGGATGAGGCGCACGAGGAGATTGTACCAGTGGCGCTGAACACTTCAGCGGGATCGTTAATCTCCAGCCAAACGGATGGTAATGGCGTTGTGGTGCGTGAGTATCTGGTGGACGAGACCGACAGCACGGCGGCTCAGACCATTACGCTGGAGAACGAGACATACACGATCCTTCCGCTGGACATCGAGGGCGAGCAGCTGGCCGACGAGTCGGCGGTGGGAGTCAAGCCCGAGGGCAAGAAGGAAGAAGGAGGAACGAAGGTCTCACCAGTGGTCAAGAAGGAGAAGCGCAAGTCCTTGGCCGCCAGCCTGGCGGCTGCCATTGCTGATAatctggaggaggagccgTCGAGCGAGGACGATGCCAGCGGCGAAGTCCTAACCGAGGAGGACGTCAAGCTTAAGGAGAACATTGGCAAGCTGATCGACATGCTGGTTGATCCGCCCATCTTGAAGAAATATGGCTGGCCCAATGCCCCCGAGGAGACGGTGCTCTGCAAGGTGATTGAGAACTGCGGCCACGACTTGACCAAAGCAGGCGAGAACTACGCTGAGCTGGACTACGGCAGTCGGATGCGCGAGTACTGCAAGCTACTCTTCACCGTCGTCATTCACAACGACTCCATCAAGTCGCTGCTCAACAACTTTCCCATCGACGATGTCATCGAGTATGTGCTGGGCGACGAGGATCAGGaggatggcggcggcggcttgggGACCAAAGGTAAGGATGCCGAAGAAGGAGAAGCAAGTACAGCGAAGAAACAGAGGAAGTCGAAAGCCGGAGAAGGGGAGACAATCACAGGTGACCCAGactccgaggaggaggatgaggaggaaaccgtcgaaaaagaaaagggcgcAGCTGAAATCGAAAGAAAGAAGGCTGTTTAG
Protein Sequence: MSASKEGKDKKGGIKILGVENISPPKDTSRPATRMKLLNEAAAAGAAASPSVSPTKTEKRNSGGGGSRIKILNDEALGLPKTEKRGATSKTNPRTSTSVKILNVKRPASATAITAMQTKIRAMPSKKQKMDHYVLQAVKTENSKQQAVTTAHRAATTENEETETIAFILADDDEVVPGTLERTNGQEEIVVTENDDEEEEEEGGEADKDEAGKGGIKEIVEHVCGKCYKTFRRIKSLTKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFCDFPCSICNANLRSEALLKLHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSACSANETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVMKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCEKKFSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGERPHKCEECGKSFIQATQLRTHSKTHVRPFPCDQCEDKFKTQKQLERHLKEHSSQKRAVFSCTECKRNFRSTAQLKEHMEVGVHTPKPQRVSKRTPAKVMERTDCAICDKNFDSCDTLRRHIRTVHECDPDDIFGVDPQTAKRGKRAKLATVAEQDQDEAHEEIVPVALNTSAGSLISSQTDGNGVVVREYLVDETDSTAAQTITLENETYTILPLDIEGEQLADESAVGVKPEGKKEEGGTKVSPVVKKEKRKSLAASLAAAIADNLEEEPSSEDDASGEVLTEEDVKLKENIGKLIDMLVDPPILKKYGWPNAPEETVLCKVIENCGHDLTKAGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEDGGGGLGTKGKDAEEGEASTAKKQRKSKAGEGETITGDPDSEEEDEEETVEKEKGAAEIERKKAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00612944;
90% Identity: iTF_00483105;
80% Identity: -