Basic Information

Insect: Drosophila bocqueti
Gene Symbol: su(Hw)
Assembly: GCA_018151655.1
Location: JAECXF010000001.1:10354345-10357551[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00063 0.048 14.1 1.9 1 20 233 252 233 254 0.94

2 12 2.5e-06 0.00019 21.7 0.4 3 23 305 326 303 326 0.93

3 12 0.068 5.2 7.7 0.1 1 23 332 354 332 354 0.94

4 12 4.9e-07 3.7e-05 23.9 2.4 1 21 361 381 361 382 0.95

5 12 5.5e-06 0.00042 20.6 1.0 2 23 394 415 393 415 0.96

6 12 9.3e-05 0.0071 16.7 5.3 1 23 426 448 426 448 0.99

7 12 0.00025 0.019 15.3 0.8 1 23 454 476 454 476 0.97

8 12 1.7e-05 0.0013 19.1 0.4 1 23 482 504 482 504 0.98

9 12 1.4e-06 0.0001 22.5 2.5 1 23 510 532 510 532 0.98

10 12 5.7e-06 0.00044 20.5 1.6 1 23 536 558 536 558 0.98

11 12 5.8e-05 0.0044 17.4 0.4 1 22 566 587 566 590 0.91

12 12 1.1e-05 0.00081 19.7 1.4 3 23 611 632 609 632 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00063	0.048	14.1	1.9	1	20	233	252	233	254	0.94
2	12	2.5e-06	0.00019	21.7	0.4	3	23	305	326	303	326	0.93
3	12	0.068	5.2	7.7	0.1	1	23	332	354	332	354	0.94
4	12	4.9e-07	3.7e-05	23.9	2.4	1	21	361	381	361	382	0.95
5	12	5.5e-06	0.00042	20.6	1.0	2	23	394	415	393	415	0.96
6	12	9.3e-05	0.0071	16.7	5.3	1	23	426	448	426	448	0.99
7	12	0.00025	0.019	15.3	0.8	1	23	454	476	454	476	0.97
8	12	1.7e-05	0.0013	19.1	0.4	1	23	482	504	482	504	0.98
9	12	1.4e-06	0.0001	22.5	2.5	1	23	510	532	510	532	0.98
10	12	5.7e-06	0.00044	20.5	1.6	1	23	536	558	536	558	0.98
11	12	5.8e-05	0.0044	17.4	0.4	1	22	566	587	566	590	0.91
12	12	1.1e-05	0.00081	19.7	1.4	3	23	611	632	609	632	0.97

Sequence Information

Coding Sequence: ATGAGCGCGTCCAAGGAGGGCAAGGACAGGAAGGGCGGAATCAAGATTCTGGGAATGGAGAACATCTCGCCGCCGAAGGAAACGTCGCGCCCCGCCACACGCATGAAGCTGCTGAACGAGGCCGCAGCAGCAGCAGGAGCCTCTGCTCCATCTTCGTCTCTTTCCCCAACCAAGACGGAAAAGCGCAACAGCGGCGGCGGCGGTGGGGGATCCCGCATCAAAATACTCAATGACGAGGCACTGGGACTGCCGAAGAACGAGAAACGTGGCTCAACATCTAAGACCAGTCCTCGCAACACCACCGCCGCCACCACCTCCACCTCAGTGAAGATCTTAAATGTAAAGCGCCCTGCCTCCACCACCACCTCCAGTACAGCCCTGGAAACCAAGAACCGTGCCTCCCCCGGCAAGAACAAGAAGATGGATCACTACGTGCTCCAAGCTGTCAAGTTGGAGAACACCAAGCAGCAAGCAGTCACCACGGCGCACCGTGCGGCCGCGTCTGAAAGCGAGGAGACCGAGACCATTGCCTTCATACTGGCGGACGACGACGAGGTGGTGCCAGGAACGTTGGAACGGACGAACGGCCAGGAGGAGATCGTCGTGACCGAAAACGATGAGGAGGAGGAGGAGGAGGAAGGCGGCGAGGCGGAAAAGGACGAGGTTGGCAAGGGCGGGATGAAGGAGATTGTGGAACATGTGTGCGGCAAGTGCTACAAGACCTTCCGGCGCATCAAGAGCCTGACGAAGCATTTGGAGTTCTGTCGCTACGACAGCGGCTACCACCTGCGCAAGGCGGACATGCTCAAGAACCTGGAGAAGATCGAGAAGGATGCGGTGGTGATGGAGAAGAAGGATATATGTTTCTGCTGCAGCGAAAGCTACGACACCTTCCATTTGGGCCACATCAACTGTCCGGACTGCCCAAAGTCGTTCAAGACGCAAACCAGCTACGAGCGTCACATCTTTATCACGCACTCGGAGTTTTGTGACTTTCCCTGCTCCATTTGCAATGCCAATCTGCGCAGCGAGGCGTTGCTGAAGCTCCACGAGGAGCAGCACAAGTCAAGGGGCAAGCCGTACGCCTGCAAGATCTGCGGCAAGGATTTCACGCGCTCCTATCACCTGAAGCGCCATCAGAAATACTCGGCCTGCTCGGCCAATGAGACCGATACGATGAGCTGCAAGGTTTGCGATCGCGTCTTTTATCGTTTGGACAACCTGCGATCGCACTTGAAGCAGCATTTGGGCACGCAGGTGATGAAGAAGCCGGAGTACATGTGTCACGTTTGCAAGAATTGCTTCTACAGCTTGTCCACGCTCAACATTCACATACGCACGCATACGGGCGAGAAGCCTTTCGATTGCGATCTATGTGAGAAGAAGTTCTCAGCTCTGGTGGCCCTGAAGAAGCATCGTCGCTATCACACGGGCGAGAAACCTTACAGCTGCACTGTGTGCAATCAAGCCTTTGCTGTGAAGGAGGTCCTCAATCGCCACATGAAACGGCACACGGGCGAGCGTCCGCACAAGTGTGAGGAGTGTGGCAAGAGCTTCATCCAGGCAACACAGCTGCGCACGCATTCCAAGACCCACGTTCGGCCCTTTCAATGCGATCAATGCGAGGAGAAGTTCAAGACGCAGAAGCAACTTGAGCGTCATGTGAAGGAGCACAATTCACAGAAGCGCCCCGTCTTCTCCTGCACCGAATGCAAGCGCAATTTCCGCAGCACAGCTCAGCTCAAGGAACACATGGATGTGGGCGTTCACACACCCAAGCCGACGCGTGCCACCAAGCGCTCGCCCGCCAAGGTTATGGAGCGCACGGATTGCGCCATTTGTGACAAGAACTTCGACAGCTGCGAAACCCTTCGCCGGCACATTCGCACCGTCCACGAATGCGATCCGGATGACATCTTTGGCGTGGATCCGCTAATAGCGAAACGTGGCAAGAGAGCCAAATTGGCGACGGTGGAGGAGCAGGATCAGGATCAGGAGGAGATTGTACCAGTGGCGCTGAACACTTCAGCGGGTTCGTTGATTTCCAGCCAAACGGATGGCAATGGCGTTGTGGTGCGCGAGTATTTGGTGGACGAGACCGACGAGACGGCGGCCCAGACCATTACGCTTGAGAACGAAACATATACGATTCTCCCGCTGGACATCGAGGGCGAGCAGCTAACGGATGAGACGCCGCCGCCTGTGGCAGTCAAGCCCGAGGGCAAAAAGGAAGAAGGAGGCGGAGGCGGCCTGAAGGTCTCGCCGGTGGTCAAGAAGGAGAAGCGCAAGTCGTTGGCTGCCAGCTTGGCGGCTGCTATCGCTGATAATTTGGAGGAGGAGCCATCCAGCGAGGACGATGGCAGCGGCGAAGTCTTAACCGCGGAGGACCTTAAGCTCAAGGAGAACATTGGCAAACTGATCGACATGCTGGTGGATCCGCCCATCCTGAAGAAGTATGGCTGGCCCAATGCCCCCGAAGAGTCGGTGCTCTGCAAGGTGATCGAGAACTGCGGCCACGACCTGACCAAAGGTAGTGAGAACTACGCGGAGCTGGACTACGGCAGCCGGATGCGCGAGTACTGCAAGCTGCTCTTCACCGTGGTCATACACAACGACTCCATCAAGTCGCTGCTCAACAACTTTCCCATCGACGATGTCATCGAGTATGTCTTGGGTGATGAGGATCAGGAGGAAGGCGGCGGTGGCTTGGGCGGTGGCATAGGTAAGGCCGACGAGGAGCCGGACGAAGAAGAACTAAGTACAGCGAAGAAGCGTAAAAGGTCGGAAACCGAGATAGGAGAGACAATCACCGGTGATTTGGATTCCGAGGGGGAGAACGAGGAAGCAGCGGTCGAAAAGGAAAAGGAGACACCTGAAAAAGTAGGAAAAAAGGTTTGA
Protein Sequence: MSASKEGKDRKGGIKILGMENISPPKETSRPATRMKLLNEAAAAAGASAPSSSLSPTKTEKRNSGGGGGGSRIKILNDEALGLPKNEKRGSTSKTSPRNTTAATTSTSVKILNVKRPASTTTSSTALETKNRASPGKNKKMDHYVLQAVKLENTKQQAVTTAHRAAASESEETETIAFILADDDEVVPGTLERTNGQEEIVVTENDEEEEEEEGGEAEKDEVGKGGMKEIVEHVCGKCYKTFRRIKSLTKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFCDFPCSICNANLRSEALLKLHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSACSANETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVMKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCEKKFSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGERPHKCEECGKSFIQATQLRTHSKTHVRPFQCDQCEEKFKTQKQLERHVKEHNSQKRPVFSCTECKRNFRSTAQLKEHMDVGVHTPKPTRATKRSPAKVMERTDCAICDKNFDSCETLRRHIRTVHECDPDDIFGVDPLIAKRGKRAKLATVEEQDQDQEEIVPVALNTSAGSLISSQTDGNGVVVREYLVDETDETAAQTITLENETYTILPLDIEGEQLTDETPPPVAVKPEGKKEEGGGGGLKVSPVVKKEKRKSLAASLAAAIADNLEEEPSSEDDGSGEVLTAEDLKLKENIGKLIDMLVDPPILKKYGWPNAPEESVLCKVIENCGHDLTKGSENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEEGGGGLGGGIGKADEEPDEEELSTAKKRKRSETEIGETITGDLDSEGENEEAAVEKEKETPEKVGKKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00612944;
90% Identity: iTF_00492363;
80% Identity: -