Dasa008833.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila asahinai
Gene Symbol
su(Hw)
Assembly
GCA_008042795.1
Location
VNJZ01002188.1:24145-27402[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00063 0.057 14.1 1.9 1 20 229 248 229 250 0.94
2 12 2.5e-06 0.00022 21.7 0.4 3 23 301 322 299 322 0.93
3 12 0.068 6.2 7.7 0.1 1 23 328 350 328 350 0.94
4 12 4.9e-07 4.4e-05 23.9 2.4 1 21 357 377 357 378 0.95
5 12 5.5e-06 0.0005 20.6 1.0 2 23 390 411 389 411 0.96
6 12 0.00025 0.023 15.4 6.3 1 23 422 444 422 444 0.99
7 12 0.00025 0.023 15.4 0.8 1 23 450 472 450 472 0.97
8 12 1.7e-05 0.0015 19.1 0.4 1 23 478 500 478 500 0.98
9 12 1.4e-06 0.00012 22.5 2.5 1 23 506 528 506 528 0.98
10 12 7.3e-05 0.0067 17.1 0.9 3 23 534 554 532 554 0.97
11 12 5.8e-05 0.0052 17.4 0.4 1 22 562 583 562 586 0.91
12 12 6.9e-06 0.00062 20.3 1.5 3 23 607 628 605 628 0.97

Sequence Information

Coding Sequence
ATGAGCGCCGCCAAGGAGGGCAAGGACAAGAAGGGCGGCGTCAAGATACTGGGCGTGGAGAACGTCTCGCCGCCGAAGGACACGTCGCGCCCCGCCACGCGCATGAAGCTGCTGAACGAGGCCGCAGCAGCGGGAGCCGCTTCGTCGCCGTCTGTTTCCCCCACCAAGACGGAGAAGCgcaacagcggcggcggcggcgggggatCCCGCATCAAAATACTCAATGACGAGGCCCTGGGCCTGCCAAAGACCGAGAAGCGGGGCTCCTTATCCAAGACCAGTCCGCGGaacaacaccaccaccaccacctccacctccgTGAAGATCCTCAATGTAAAGCGccctgccaccgccaccgccgtgACGCCCCTGGAGACCAAGATCCGAGCCTCGCCCGGCAAGAAGCAGAAGATGGATCACTATGTTCTCCAAGCGGTCAAGTTGGAGAACAGCAAGCAGCAAGCGGTCACCACGGCGCACCGCGCGGCGGCGTCGGAGCACGATGAGACCGAGACTATTGCCTTTATACTGGCCGAAGACGATGAGGTGGTGCCGGGCACGTTGGAACGGACGAATGGCCAGGAAATCGTCGTCACCGAaggcgacgaggaggaggacgacgacgacggcgtcGAGGCGGACAAGAGCGAGGGCGGCAAGGGGGGGATCAAGGAGATTGTGGAGCATGTGTGCGGCAAGTGCTACAAGACGTTCCGGCGCATCAAGAGCCTGACGAAGCACTTAGAGTTCTGCCGCTACGACAGCGGCTACCATCTGCGCAAGGCGGACATGCTCAAGAACCTGGAGAAGATCGAGAAGGATGCGGTGGTGATGGAGAAGAAGGATATCTGTTTCTGCTGCAGCGAAAGCTACGACACCTTCCATTTGGGCCACATCAACTGTCCCGACTGCCCCAAGTCGTTCAAGACACAGACCAGCTACGAGCGCCACATCTTCATCACACACTCGGAGTTCTGCGACTTTCCCTGCTCCATCTGCAATGCCAATCTGCGCAGCGAGGCGCTGCTGAAGCTGCACGAGGAGCAGCACAAGTCGCGGGGCAAGCCGTATGCCTGCAAGATCTGCGGCAAGGACTTTACGCGCTCGTACCATTTGAAGCGCCATCAGAAGTACTCGGCGTGCTCGGCCAATGAGACCGATACCATGAGCTGCAAGGTCTGCGACCGCGTCTTTTATCGCCTGGACAACCTGCGCTCGCACCTGAAGCAGCACCTGGGCACGCAGGTGATGAAGAAGCCCGAGTACATGTGTCACACGTGCAAGAACTGCTTCTACAGCTTGTCCACGCTCAACATTCACATACGCACGCACACGGGCGAGAAGCCCTTCGATTGCGATCTCTGCGAGAAGAAGTTCTCCGCCTTGGTGGCCCTCAAGAAGCATCGTCGCTATCACACGGGCGAGAAGCCCTACAGCTGCACTGTGTGCAACCAAGCCTTTGCCGTCAAGGAGGTGCTCAATCGGCACATGAAGCGGCACACGGGCGAGCGGCCGCACAAGTGCGAGGAGTGTGGCAAGAGCTTCATCCAGGCCACGCAGCTGCGCACCCATTCCAAGACCCACGTGCGGCCCTTTGGCTGTGATCAGTGCGAGGAGAAGTTCAAAACGCAGAAGCAACTCGAGCGCCATGTCAAGGAGCACTCTTCCCAGAAGCGTCCCGTCTTCTCCTGCACCGAATGCAAGCGCAACTTCCGCAGCACAGCCCAGCTCAAGGAACACATGGATGTCGGTGTACACACACCCAAGCCCACGCGCGCCGTCAAGCGCTCGCCCACCAAGGTTATGGAGCGCACGGATTGCGCCATTTGTGACAAGAACTTCGACAGCTGCGACACTCTCCGCCGGCACATCCGCACCGTGCACGAATGCGATCCGGATGACATCTTTGGCGTGGATCCTCAAACTGCGAAGCGTAGCAAGAGGGCCAAGCTGGCAACAgcggaggagctgcaggagcaggagcaggagccggaggagaTTGTACCAGTGGCACTGAACACTTCAGCGGGATCACTGATCTCCAGCCAAACCGATGGCAACGGCGTGGTGGTGCGTGAGTATCTGGTGGACGAGACCGATGACACGGCGGCCCAGACCATTACGCTGGAGAACGAGACGTACACGATTCTCCCGCTGGACATTGAGGGCGAGCAGCTGGCGGATGAGACGGCGGCGGTGGGAGTCAAGCCCGAGGGGAAGAAGGAGGAAGGCGTGAAGGTCTCGCCGGTGGTCAAGAAGGAGAAGCGCAAATCGTTGGCCGCCAGCCTGGCGGCTGCCATTGCTGATAatctggaggaggagccgtCGAGCGAGGACGATGCTAGCGGCGGCGAAGTCCTGACCGAGGAGGACCTCAAGCTCAAGGAGAACATTGGCAAGCTGATCGACATGCTGGTGGATCCGCCCATCCTAAAGAAATATGGCTGGCCCAACGCCCCCGAGGAGACGGTGCTCTGCAAGGTGATCGAGAACTGCGGCTACGACCTGGTTAAGGGTGGCGAGAACTACGCGGAGCTGGACTATGGCAGCCGGATGCGCGAGTACTGCAAGCTGCTCTTCACCGTCGTCATACACAACGACTCCATCAAGTCGCTGCTGAACAACTTTCCCATCGACGACGTCATCGAGTATGTGCTGGGCGATGAGGATCAGGAGGATGGCGGCGGGCTGGGATGCAAGGGCAAGGACGCCGACGAAGAAGAGCCGGAAGAGGGGGAAAACAGTCCAACGAAGAAAGCCGAAAAAGCAGAGACAATCACAGGCGATCCGGAGTCCGAGGAGGAAACGGTCGGTAAGGAAAAGGACAAAGCTGAAATCGAAGGAAAGAAGGCGACTGTTTAG
Protein Sequence
MSAAKEGKDKKGGVKILGVENVSPPKDTSRPATRMKLLNEAAAAGAASSPSVSPTKTEKRNSGGGGGGSRIKILNDEALGLPKTEKRGSLSKTSPRNNTTTTTSTSVKILNVKRPATATAVTPLETKIRASPGKKQKMDHYVLQAVKLENSKQQAVTTAHRAAASEHDETETIAFILAEDDEVVPGTLERTNGQEIVVTEGDEEEDDDDGVEADKSEGGKGGIKEIVEHVCGKCYKTFRRIKSLTKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFCDFPCSICNANLRSEALLKLHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSACSANETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVMKKPEYMCHTCKNCFYSLSTLNIHIRTHTGEKPFDCDLCEKKFSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGERPHKCEECGKSFIQATQLRTHSKTHVRPFGCDQCEEKFKTQKQLERHVKEHSSQKRPVFSCTECKRNFRSTAQLKEHMDVGVHTPKPTRAVKRSPTKVMERTDCAICDKNFDSCDTLRRHIRTVHECDPDDIFGVDPQTAKRSKRAKLATAEELQEQEQEPEEIVPVALNTSAGSLISSQTDGNGVVVREYLVDETDDTAAQTITLENETYTILPLDIEGEQLADETAAVGVKPEGKKEEGVKVSPVVKKEKRKSLAASLAAAIADNLEEEPSSEDDASGGEVLTEEDLKLKENIGKLIDMLVDPPILKKYGWPNAPEETVLCKVIENCGYDLVKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEDGGGLGCKGKDADEEEPEEGENSPTKKAEKAETITGDPESEEETVGKEKDKAEIEGKKATV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00612944;
90% Identity
iTF_00483105;
80% Identity
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