Basic Information

Insect: Drosophila seguyi
Gene Symbol: su(Hw)
Assembly: GCA_008042675.1
Location: VNJU01005497.1:3228-6399[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00063 0.046 14.1 1.9 1 20 230 249 230 251 0.94

2 12 2.5e-06 0.00018 21.7 0.4 3 23 302 323 300 323 0.93

3 12 0.068 4.9 7.7 0.1 1 23 329 351 329 351 0.94

4 12 4.8e-07 3.5e-05 23.9 2.4 1 21 358 378 358 379 0.95

5 12 5.5e-06 0.0004 20.6 1.0 2 23 391 412 390 412 0.96

6 12 9.3e-05 0.0068 16.7 5.3 1 23 423 445 423 445 0.99

7 12 0.00025 0.018 15.4 0.8 1 23 451 473 451 473 0.97

8 12 1.7e-05 0.0012 19.1 0.4 1 23 479 501 479 501 0.98

9 12 1.4e-06 9.9e-05 22.5 2.5 1 23 507 529 507 529 0.98

10 12 2.2e-06 0.00016 21.9 2.0 1 23 533 555 533 555 0.98

11 12 5.8e-05 0.0042 17.4 0.4 1 22 563 584 563 587 0.91

12 12 1.1e-05 0.00077 19.7 1.4 3 23 608 629 606 629 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00063	0.046	14.1	1.9	1	20	230	249	230	251	0.94
2	12	2.5e-06	0.00018	21.7	0.4	3	23	302	323	300	323	0.93
3	12	0.068	4.9	7.7	0.1	1	23	329	351	329	351	0.94
4	12	4.8e-07	3.5e-05	23.9	2.4	1	21	358	378	358	379	0.95
5	12	5.5e-06	0.0004	20.6	1.0	2	23	391	412	390	412	0.96
6	12	9.3e-05	0.0068	16.7	5.3	1	23	423	445	423	445	0.99
7	12	0.00025	0.018	15.4	0.8	1	23	451	473	451	473	0.97
8	12	1.7e-05	0.0012	19.1	0.4	1	23	479	501	479	501	0.98
9	12	1.4e-06	9.9e-05	22.5	2.5	1	23	507	529	507	529	0.98
10	12	2.2e-06	0.00016	21.9	2.0	1	23	533	555	533	555	0.98
11	12	5.8e-05	0.0042	17.4	0.4	1	22	563	584	563	587	0.91
12	12	1.1e-05	0.00077	19.7	1.4	3	23	608	629	606	629	0.97

Sequence Information

Coding Sequence: ATGAGCGCGTCCAAGGAGGGCAAGGACAAGAAGGGCGGACTCAAGATTCTGGGAGTGGAAAACATCTCGCCGCCGAAGGAAACGTCGCGCCCCGCCACACGCATGAAGCTGCTGAACGAggccgcagcagcaggcgccTCAGCTGCGTCTCCGTCTGTTTCACCAACCAAGACGGAAAAGCgcaacagcggcggcggtgggggATCCCGCATTAAAATACTCAATGACGAGGCACTGGGCCTGCCAAAGACCGAGAAACGTGGCTCAACATCTAAAACCAGTCCACGCAACACCACCGCCACCTCCACCTCTGTAAAGATCTTAAATGTAAAGCGCCCAGCCTCCGCCACCTCCATTACAGCCCTGGAAACCAAGAACCGCGCCTCACCCAGCAAGAAGCAGAAGATGGATCACTACGTGCTCCAAGCGGTCAAGGTGGAGAACACCAAGCAGCAAGCAGTCACCACGGCGCACCGTGCGGCGACTTCGGAAAACGAGGAGACCGAAACCATTGCCTTCATACTGGCGGACGACGACGAGGTGGTGCCAGGAACGTTGGAACGGACGAATGGCCAGGAGGAGATCGTCGTGACCGAAaacgatgaggaggaggaggaggaagaagagGAAGGCGGCGAGGCGGGTAAGAACGAAGCTGGCAAAGGCGGGATGAAGGAGATTGTGGAACATGTGTGCGGCAAATGCTACAAGACCTTCCGGCGGATCAAGAGCCTGACGAAGCATTTGGAGTTCTGTCGTTACGACAGCGGCTACCACCTTCGCAAGGCAGACATGCTAAAGAACCTGGAGAAGATCGAGAAGGATGCGGTGGTGATGGAAAAGAAGGATATCTGTTTCTGCTGCAGCGAGAGCTACGACACCTTTCATTTGGGCCACATCAACTGTCCGGACTGCCCAAAGTCGTTTAAGACTCAAACCAGCTACGAGCGCCACATCTTCATCACGCACTCTGAATTTTGTGACTTTCCCTGCTCCATCTGCAATGCCAATCTGCGCAGCGAGGCGTTGCTGAAGCTCCACGAGGAACAGCACAAGTCTAGGGGCAAGCCGTACGCCTGCAAGATCTGCGGCAAGGATTTCACGCGCTCCTATCACCTGAAGCGCCATCAGAAATACTCGGCCTGCTCGGCCAATGAGACCGATACCATGAGTTGCAAAGTTTGCGATCGTGTCTTTTATCGCTTGGACAACCTGCGATCGCACTTGAAGCAGCATTTGGGCACGCAGGTGATGAAGAAGCCGGAGTACATGTGTCACGTTTGCAAGAATTGCTTCTACAGCTTGTCCACGCTCAACATTCACATACGCACGCATACGGGCGAGAAGCCTTTCGATTGCGATCTATGCGAAAAGAAGTTCTCAGCTTTGGTGGCCCTTAAGAAGCATCGTCGCTATCACACGGGCGAGAAACCCTACAGCTGCACTGTGTGTAATCAAGCCTTTGCTGTGAAGGAGGTCCTCAATCGCCACATGAAACGGCACACAGGCGAGCGTCCGCACAAGTGTGAGGAGTGTGGCAAAAGTTTTATCCAGGCTACACAGTTGCGCACGCATTCCAAGACGCACGTTCGACCCTTCAGCTGTGATCAGTGCGAGGAGAAGTTCAAGACGCAGAAGCAACTTGAACGTCATATGAAGGAGCACAATTCCCAGAAGCGCCCCGTTTTCTCGTGCACTGAATGTAAGCGCAATTTCCGCAGCACAGCTCAGCTTAAGGAGCACATGGATGTGGGCGTACACACACCCAAGCCCACGCGTGCCACCAAGCGCTCGCCCGCCAAGGTTATGGAGCGCACGGATTGCGCCATTTGTGACAAAAACTTCGACAGCTGCGAAACTCTTCGCCGGCACATCCGCACCGTCCACGAATGTGATCCGGATGATATCTTTGGCGTGGATCCGCTAGTAGCGAAGCGTGGCAAGAGAGCCAAATTGGCGACGgtggaggagcaggaacaggatcATGAGGAGGTTGTACCAGTGGCGCTGAACACTTCAGCGGGTTCGTTAATCTCCAGCCAAACGGATGGCAATGGCGTTGTGGTGCGTGAATATCTTGTGGACGAGACCGATGAGACGGCGGCCCAGACCATTACGCTTGAGAACGAGACCTATACCATTCTCCCGCTGGACATGGAGGGCGAGCAGCTGACGGATGAGACGTCTGTGGCAGTCAAGCCCGAGAGCAAAAAGGAAGAGGGAGGCCTGAAGGTCTCGCCGGTGGTCAAGAAGGAGAAGCGCAAGTCGTTGGCTGCCAGCTTGGCGGCTGCTATCGCTGATAATTTGGAGGAAGAGCCATCCAGCGAGGAAGATGGCAGCGGCGAAGTCTTAACCGAGGAGGACCTCAAGCTTAAGGAAAACATTGGCAAACTGATCGACATGCTGGTGGATCCGCCCATCTTGAAGAAGTATGGCTGGCCCAATGCTCCCGAAGAGTCGGTGCTCTGCAAGGTGATCGAGAACTGCGGCCACGATCTGACCAAAGGTAGTGAGAACTACGCGGAGTTGGACTATGGCAGCCGGATGCGCGAGTACTGCAAGCTGCTCTTCACCGTGGTCATACACAACGACTCCATCAAATCGCTGCTAAACAACTTTCCCATTGACGATGTCATCGAGTATGTACTGGGCGATGAGGATCAGGAGGAAGGCGGTGGCTTGGGCGGCTTAGATAAGGACGACGAAGAAGGGGAACCGGAAGAAGAAGTAAGTGCGACAAAGAAACGGAAAAAGTCGGAAACCGAGATAGGAGAGACAATCACAGGGGATCTGGattccgaggaggaggacgaggaaaAGGtcgaaaaggaaaagaacacagctgaaaaaaaaggaaaaaggactTGA
Protein Sequence: MSASKEGKDKKGGLKILGVENISPPKETSRPATRMKLLNEAAAAGASAASPSVSPTKTEKRNSGGGGGSRIKILNDEALGLPKTEKRGSTSKTSPRNTTATSTSVKILNVKRPASATSITALETKNRASPSKKQKMDHYVLQAVKVENTKQQAVTTAHRAATSENEETETIAFILADDDEVVPGTLERTNGQEEIVVTENDEEEEEEEEEGGEAGKNEAGKGGMKEIVEHVCGKCYKTFRRIKSLTKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFCDFPCSICNANLRSEALLKLHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSACSANETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVMKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCEKKFSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGERPHKCEECGKSFIQATQLRTHSKTHVRPFSCDQCEEKFKTQKQLERHMKEHNSQKRPVFSCTECKRNFRSTAQLKEHMDVGVHTPKPTRATKRSPAKVMERTDCAICDKNFDSCETLRRHIRTVHECDPDDIFGVDPLVAKRGKRAKLATVEEQEQDHEEVVPVALNTSAGSLISSQTDGNGVVVREYLVDETDETAAQTITLENETYTILPLDMEGEQLTDETSVAVKPESKKEEGGLKVSPVVKKEKRKSLAASLAAAIADNLEEEPSSEEDGSGEVLTEEDLKLKENIGKLIDMLVDPPILKKYGWPNAPEESVLCKVIENCGHDLTKGSENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEEGGGLGGLDKDDEEGEPEEEVSATKKRKKSETEIGETITGDLDSEEEDEEKVEKEKNTAEKKGKRT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00612944;
90% Identity: iTF_00492363;
80% Identity: -