Dtri002048.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila triauraria
Gene Symbol
-
Assembly
GCA_014170255.2
Location
CM024333.1:15739099-15740973[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.2 15 6.2 0.5 6 23 256 273 256 273 0.99
2 9 0.0069 0.53 10.8 1.0 1 23 279 302 279 302 0.97
3 9 4.8e-05 0.0037 17.6 1.8 1 23 310 332 310 332 0.97
4 9 7.2e-07 5.5e-05 23.4 3.3 2 23 339 361 339 361 0.98
5 9 1.2e-05 0.0009 19.5 0.7 1 23 368 391 368 391 0.97
6 9 0.06 4.6 7.9 0.2 2 23 401 422 400 422 0.95
7 9 0.091 7 7.3 0.3 2 23 432 453 431 454 0.93
8 9 9e-06 0.00069 19.9 3.7 1 23 459 481 459 481 0.98
9 9 0.00011 0.0083 16.5 3.7 1 23 487 510 487 510 0.97

Sequence Information

Coding Sequence
ATGATTTGCCGACTCTGTCTGGACGACGCGGTGCACAGCATCCCGATCTTCGACCAGGAGGAGGCCGACGACCAGCCGCCGCCCTCCAACCTGGCAGAGCTGATTGAGAAGCACCTGCAGTTGGTCCTGCTGCCCAACGATGCTGTCTCCCGGTGCCTGTGCACCCAGTGCTGGCAGCAATTGGCCGACTTTGAACAATTCTGCACCATGGTGATGAAGAAGCAGCTGGACCTGCAGCAGCTCAAGCTGGAGCCCTTCTCCGACGAGGAAGAGGACGCGGACACGAAGGCGCACATCTTGTGCGAGCCCGAGATCGATGTCAGTCCCTCGGCGGCGGAAAACGAGGAGTACAACGAGATCGATGTGGATGCCACCAGCAGTAGCAGCACCACACACGCTGCAGGGGCGGCGGCGGCGGCACCTGGTGGACGGACGACAACGCGGCGCTCTAGGGTGCGTCTGCCGTCGCCCATTAGACGCAGCATGCGTCCCAGAGCGCTTCCAAAGGCCAGGGCCGTGAAGGCCACCAAGGCCAAGACGAAGCGCCAGCTGGAGGAGGCGGACGAGGATGAGGACGCAGAAGGCGATGGCGACGGGGATCCCGAGAGCCGGAGTAGCCACAGCCGCGAAATGGACACTTACATAGCGCTACATGGCCGCCTGGAGTGTTGCTTGTGCGGCGGCGACGACGACCAATTTCAGAACTTTGCCGAGATGAAGCGACACTTCCGCAATCATCATCAGTCCGCCGGCTACGTGGTGTGCTGCCAGCGACGCTACAAGAAGCGGGCGCTCTACGTCGACCACCTGCGCATGCACAACGATCCGGATTACTTTAGGTGCAAGATCTGCTCAAAGCAGCTTGTCAGCCGGATCAGCTACGACGTCCACATGCTGCGCTTCCACTCGAACGAGGACGAGCTGAGCTTTGCCTGCGACAAGTGCTCCAAGCGGTTCTCCAAGCAATTCCTGCTCACCATCCATTCGCGAGTCCACCAGCAGGAGCGGAAGGAGCAGTGCAAGCACTGCGACAGATCCTTCCGCACTGCCGTGGACCTGCGACTCCATATGCGACGCACCCACGATCCCGCATTCGTGCCCTTCATCTGCGACTCGTGCGGAGCCAAGTTCAAGACGAAACAGAACCTGCTTGTCCACAAGCGCACCGTACACCGCGAGGGCTCCCAGCTGCCGGAGGTGCAGTGCCAGGAGTGCCAGGTGTGGTTATCCGACGAGAACAGCCTGCGCAAGCACATGTACATGCACCTGGACGCCGCCTCGCTGCGCCAGTGGAAGTGCGAGCAGTGCGGCCTGGAGAAGGGCTCGCGAGCGAAGCTGGCCGCCCACATCCGCTACCACCATCCAAAGGAATATCACAAGTGCACGCACTGCGGCAAGGAGTTCAAGAGCAGCCGGGGCCTCGAGGAGCACACGGCCACGCACACCGGCCAGGATCTGTACGAGTGCGCCTTTTGCGAGCGCACCTTCAAGAATTCGGGCAACATGCACAAGCACCGCCGCCAGATGCACGCCGCCCAGGTGGCCGCCCTCCAGCAGCAGAAGAAGGTGCGTCCCAGCAAGCGTAAGGACAAGGGCGAACTGATGCTCGGTGTCCTGGCTGCCGGCGGAAAGGACATAATGAACCATGCGATGGGCAACGCCGGCGACTTAAACATGAATATGAACATGAACGACTGA
Protein Sequence
MICRLCLDDAVHSIPIFDQEEADDQPPPSNLAELIEKHLQLVLLPNDAVSRCLCTQCWQQLADFEQFCTMVMKKQLDLQQLKLEPFSDEEEDADTKAHILCEPEIDVSPSAAENEEYNEIDVDATSSSSTTHAAGAAAAAPGGRTTTRRSRVRLPSPIRRSMRPRALPKARAVKATKAKTKRQLEEADEDEDAEGDGDGDPESRSSHSREMDTYIALHGRLECCLCGGDDDQFQNFAEMKRHFRNHHQSAGYVVCCQRRYKKRALYVDHLRMHNDPDYFRCKICSKQLVSRISYDVHMLRFHSNEDELSFACDKCSKRFSKQFLLTIHSRVHQQERKEQCKHCDRSFRTAVDLRLHMRRTHDPAFVPFICDSCGAKFKTKQNLLVHKRTVHREGSQLPEVQCQECQVWLSDENSLRKHMYMHLDAASLRQWKCEQCGLEKGSRAKLAAHIRYHHPKEYHKCTHCGKEFKSSRGLEEHTATHTGQDLYECAFCERTFKNSGNMHKHRRQMHAAQVAALQQQKKVRPSKRKDKGELMLGVLAAGGKDIMNHAMGNAGDLNMNMNMND